Stem cell therapy and transplantation, also known as regenerative medicinal process of peripheral blood stem cell transplant, promotes the reparative response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. The ultimate goal of stem cell therapy is to replace unhealthy cells with healthy ones and to allow proper cell functioning in the human body. The potential uses for stem cell... Readmore

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Khalid Ahmed Al-Anazi

Khalid Ahmed Al-Anazi | Editor-in-Chief

Consultant and Chairman of Department, King Fahad Specialist Hospital, Dammam, Saudi Arabia, Email:;  Tel: 00966506444738

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Recent Articles

2019-12-18 Review Article

A review on the occurrence of opportunistic infections after applications of stem cell techniques

Hasan Hosainzadegan*, Parviz Vahedi and Mortaza Hosainzadegan

<h2>Abstract</h2> <p>In recent years, stem cells technology have been used widely in basic and clinical science researches LIPUS (low-intensity pulsed ultrasound) is another technique commonly used in conjunction with stem cells that can have complications after applications. On...

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2019-12-09 Review Article

Natural killer cells in patients with hematologic malignancies, solid tumors and in recipients of hematopoietic stem cell transplantation

Al-Anazi KA*, Al-Jasser AM and Al-Anazi WK

<p>Natural killer cells represent the first line of defense against infections and tumors and can be derived from various sources including: bone marrow, peripheral blood, specific types of human stem cells, and certain cell lines. The functions of natural killer cells are influenced by: sever...

Read Full Article HTML DOI: 10.29328/journal.jsctt.1001017 Citation

2019-11-08 Short Communication

Human mesenchymal stem cells conditioned media promotes the wound healing process - An in vitro study

Rashi K Jain*, Devashree Vakil, Corey Cunningham and Kuldip Sidhu

Mesenchymal stem cells (MSCs) conditioned medium (CM) has a promising prospect towards skin regeneration. Therefore, human dental pulp and adipose stem cells (DPSCs and ADSCs) were isolated, propagated and evaluated for their stemness and genetic stability over time in culture before making CM...

Read Full Article HTML DOI: 10.29328/journal.jsctt.1001016 Citation

2019-10-01 Editorial

The rising role of natural killer cells in patients with malignant hematological disorders and in recipients of hematopoietic stem cell transplantation

Khalid Ahmed Al-Anazi*

Natural killer (NK) cells, the third population of lymphoid cells, comprise 5%-25% of peripheral blood (PB) lymphocytes and represent the first line of defense against infections and tumors [1-7]. They can be derived from: bone marrow, PB, cryopreserved umbilical cord blood (UCB), human embryo...

Read Full Article HTML DOI: 10.29328/journal.jsctt.1001015 Citation

2019-09-04 Review Article

Advances in the use of GABAergic interneurons for the treatment of epilepsy

Federica Frisina#, Giulia Valetti#, Giulia Zuccarini#, Luciano Conti# and Giorgio R Merlo*

Forebrain GABAergic neurons, the main inhibitory type of neuron in the cortex and hippocampus, represent a highly heterogeneous cell population that has been implicated in the predisposition to epilepsy and the onset of seizure. Earlier attempts to restore inhibition and reduce seizure in anim...

Read Full Article HTML DOI: 10.29328/journal.jsctt.1001014 Citation

2019-02-12 Research Article

Application of autologous adipose-derived stem cells for thin endometrium treatment in patients with failed ART programs

I Sudoma, L Pylyp, Y Kremenska and Y Goncharova*

One of the factors of assisted reproduction technology (ART) success is an adequate growth and development of endometrium. At the end of follicular phase of menstrual cycle endometrium reaches its greatest thickness. It is believed that there is a critical limit of endometrial thickness beyond...

Read Full Article HTML DOI: 10.29328/journal.jsctt.1001013 Citation

2018-08-28 Research Article

Preliminary Report on the Effect of Mesenchymal Stem Cell Therapy in Patients with Chronic Lung Allograft Dysfunction

Cesar A Keller*, Thomas A Gonwa, Athena L Russell, David O Hodge, David B Erasmus and Abba C Zubair

Background: Mesenchymal stem cell (MSC) effects can shift immune responses toward anti-inflammatory and tolerogenic phenotypes, potentially helping patients with bronchiolitis obliterans syndrome (BOS).

Methods: We evaluated the effect of infusing a...

Read Full Article HTML DOI: 10.29328/journal.jsctt.1001012 Citation

2018-06-13 Procedure

A flow perfusion bioreactor with controlled mechanical stimulation: Application in cartilage tissue engineering and beyond

Arshan Nazempour and Bernard J Van Wie*

To repair articular cartilage (AC) defects in osteoarthritic patients, one approach is to engineer threedimensional grafts with physicochemical properties similar to endogenous AC. Such grafts can be grown in bioreactors that provide environmental conditions favoring chondrogenesis.Studies sho...

Read Full Article HTML DOI: 10.29328/journal.jsctt.1001011 Citation

2018-04-20 Research Article

Stem cells in patients with heart failure experience

Benetti Federico* and Natalia Scialacomo

Between 2003 and 2011, 17 patients with heart failure were treated with stem cells as part of our Foundation’s Regenerative Medicine program. In several centers and countries 4 with ischemic cardiomyopathy of which 3 were surgically implanted with autologous bone marrow stem cells (ABMSC...

Read Full Article HTML DOI: 10.29328/journal.jsctt.1001010 Citation

2018-01-25 Short Communication

Stem cells in heart failure some considerations

Federico Benetti*, Natalia Scialacomo and Bruno Benetti

Stem cell treatments depend not only on the type of cell to be used but also on the different implantation techniques. Intravascular cell injections are known to rapidly separate from the vessels On the other hand, it is also well known that direct injection into the myocardium provides better...

Read Full Article HTML DOI: 10.29328/journal.jsctt.1001009 Citation