Introduction

Stem cell therapy and transplantation, also known as regenerative medicinal process of peripheral blood stem cell transplant, promotes the reparative response of diseased, dysfunctional or injured tissue using stem cells or their derivatives. The ultimate goal of stem cell therapy is to replace unhealthy cells with h... Readmore

Aim of the Journal

The Journal of Stem Cell Therapy and Transplantation aims facilitating and offering stem cell therapy and transplantation practitioners across the globe, a unique environment for integrated group initiatives on the main issues limiting better progress in stem ce... Readmore

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Articles

We publish a wide range of article types in the Clinical, Medical, Biology, Engineering, Chemistry and Pharma.

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Recent Articles

Research Article

Application of autologous adipose-derived stem cells for thin endometrium treatment in patients with failed ART programs

One of the factors of assisted reproduction technology (ART) success is an adequate growth and development of endometrium. At the end of follicular phase of menstrual cycle endometrium reaches its greatest thickness. It is believed that there is a critical limit of endometrial thickness beyond...

Read Full Article HTML DOI: 10.29328/journal.jsctt.1001013 Citation

Research Article

Preliminary Report on the Effect of Mesenchymal Stem Cell Therapy in Patients with Chronic Lung Allograft Dysfunction

Background: Mesenchymal stem cell (MSC) effects can shift immune responses toward anti-inflammatory and tolerogenic phenotypes, potentially helping patients with bronchiolitis obliterans syndrome (BOS).

Read Full Article HTML DOI: 10.29328/journal.jsctt.1001012 Citation

Procedure

A flow perfusion bioreactor with controlled mechanical stimulation: Application in cartilage tissue engineering and beyond

To repair articular cartilage (AC) defects in osteoarthritic patients, one approach is to engineer threedimensional grafts with physicochemical properties similar to endogenous AC. Such grafts can be grown
in bioreactors that provide environmental conditions favoring chondrogenesis.

Read Full Article HTML DOI: 10.29328/journal.jsctt.1001011 Citation

Research Article

Stem cells in patients with heart failure experience

Between 2003 and 2011, 17 patients with heart failure were treated with stem cells as part of our Foundation’s Regenerative Medicine program. In several centers and countries 4 with ischemic cardiomyopathy of which 3 were surgically implanted with autologous bone marrow stem cells (ABMSC...

Read Full Article HTML DOI: 10.29328/journal.jsctt.1001010 Citation Views: 4809

Short Communication

Stem cells in heart failure some considerations

Stem cell treatments depend not only on the type of cell to be used but also on the different implantation techniques. Intravascular cell injections are known to rapidly separate from the vessels On the other hand, it is also well known that direct injection into the myocardium provides better...

Read Full Article HTML DOI: 10.29328/journal.jsctt.1001009 Citation Views: 1911

Editorial

Stemness of Mesenchymal Stem Cells

Mesenchymal stem cells (MSCs) are multipotent adult stem cells that can
self-renew and differentiate into a variety of cell types including chondrocytes, osteocytes and adipocytes.

Read Full Article HTML DOI: 10.29328/journal.jsctt.1001008 Citation Views: 2770

Research Article

Intraepidermal Injections of Autologous Epidermal Cell Suspension: A new promising approach to Dermatological Disorders. Preliminary Study

Regenerative medicine is a modern approach of dermatological treatment, using Epidermal Cells of the interfollicular epidermis (ESCs) for their effect in skin regeneration in chronic ulcers and burns, melanoma, vitiligo, junctional epidermolysis bullosa.

Read Full Article HTML DOI: 10.29328/journal.jsctt.1001007 Citation Views: 4913

Case Report

Nicotinamide as a treatment option of Age-Related Macular Degeneration

Age related macular degeneration is a severe disease of mainly elderly people and leads to central vision loss because of the degeneration of the retinal pigment epithelium [1]. Genetic and environmental factors are responsible for the accumulation of extracellular material and deposit formati...

Read Full Article HTML DOI: 10.29328/journal.jsctt.1001006 Citation Views: 4508

Research Article

Arid3a regulates mesoderm differentiation in mouse embryonic stem cells

Research into regulation of the differentiation of stem cells is critical to understanding early developmental decisions and later development growth. The transcription factor ARID3A previously was shown to be critical for trophectoderm and hematopoetic development.

Read Full Article HTML DOI: 10.29328/journal.jsctt.1001005 Citation Views: 4895

Research Article

Enhancing adipose stem cell chondrogenesis: A study on the roles of dexamethasone, transforming growth factor β3 and ascorbate supplements and their combination

Varied exogenous chondrogenic factors (CFs) are implicated in promoting differentiation of stem cells along a chondrocyte lineage in the field of regenerative tissue engineering for articular cartilage repair. The effects of dexamethasone, transforming growth factor β3 (TGF-β3), asco...

Read Full Article HTML DOI: 10.29328/journal.jsctt.1001004 Citation Views: 4944