Neuroscience is also known as Neural Science. It is the study of how the nervous system develops, its structure, and what it does. Neuroscience concerned with not only the normal functioning of the nervous system, but also with what happens to the nervous system when people have neurological, psychiatric and neurodevelopmental disorders. Neurological disorders are diseases of the brain, spine and the nerves that co... Readmore

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Zuoxin Wang

Zuoxin Wang | Editor-in-Chief

Department of Psychology & Program in Neuroscience, Florida State University, USA, Email:, Tel: (850) 644-5057


Jang-Yen Wu

Jang-Yen Wu | Editor-in-Chief

Department of Biomedical Science, Florida Atlantic University, USA, Email:, Tel: (561) 297-0167


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Recent Articles

2021-07-15 Review Article

Multimodal treatment strategies in Huntington’s disease

Rajib Dutta*


Huntington’s disease (HD) is an incurable neurodegenerative disease that causes involuntary movements, emotional lability, and cognitive dysfunction. HD symptoms usually develop between ages 30 and 50, but can appear as early as 2 or as late as 80 years. Currently no ne...

Abstract Read Full Article HTML DOI: 10.29328/journal.jnnd.1001054 Cite this Article

2021-07-15 Case Report

Facial-onset sensory-motor neuronopathy, a rare variant of Huntington’s disease or chance association?

Raul Juntas-Morales, Elisa De La Cruz, Florence Esselin, Nicolas Pageot, Guillaume Taieb and William Camu*


Objectives: To describe a patient with facial-onset sensory-motor neuronopathy (FOSMN) that later developed Huntington’s disease (HD).

Case report: A 62-year-old woman complained of progressive dysphagia 8 years before referral. At initial evaluation, there wa...

Abstract Read Full Article HTML DOI: 10.29328/journal.jnnd.1001053 Cite this Article

2021-07-06 Review Article

Role of neuron specific enolase as a biomarker in Parkinson’s disease

Rajib Dutta*


Parkinson’s disease (PD) is thought to be the most common neurodegenerative disease with movement disorder. The key motor symptoms are rigidity, tremor, akinesis/hypokinesia/bradykinesia, and postural instability. However, in our day-to-day clinical practice we tend to ...

Abstract Read Full Article HTML DOI: 10.29328/journal.jnnd.1001052 Cite this Article

2021-06-29 Research Article

Endovascular management of tandem occlusions in stroke: Treatment strategies in a real-world scenario

Juan J Cirio*, Celina Ciardi, Matias Lopez, Esteban V Scrivano, Javier Lundquist, Ivan Lylyk, Nicolas Perez and Pedro Lylyk

The association between intracranial large vessel occlusion (LVO) and concurrent steno-occlusive lesion of an ipsilateral extracranial internal carotid artery (ICA) is considered a tandem occlusion (TO) [1].

Abstract Read Full Article HTML DOI: 10.29328/journal.jnnd.1001051 Cite this Article

2021-06-09 Review Article

Differential diagnosis of POLG related disorders: What to keep in mind when multiorgan system is involved?

Rajib Dutta*


Mitochondrial and lysosomal dysfunction accounts for a large group of inherited metabolic disorders most of which are due to a dysfunctional mitochondrial respiratory chain (MRC) leading to deficient energy production and defects in phagocytosis in endosomal-lysosomal pathway...

Abstract Read Full Article HTML DOI: 10.29328/journal.jnnd.1001050 Cite this Article

2021-06-03 Review Article

Endocannabinoidome and its role in neurological disorders-A comprehensive update of existing literature

Rajib Dutta*


Medical benefits of cannabis and related compounds is widely known. Discovery of psychotropic plant cannabinoid Δ9-tetrahydrocannabinol have urged researchers to study more about the cannabinoid system and related therapeutics in the field of neurology and medicine. Whe...

Abstract Read Full Article HTML DOI: 10.29328/journal.jnnd.1001049 Cite this Article

2021-05-11 Research Article

Factors associated with mortality after decompressive craniectomy in large basal ganglia bleeds

Amit Kumar Thotakura*, Nageswara Rao Marabathina, Rama Krishnareddy Mareddy and Sivaramanjaneyulu Yeddanapudi


Aim: To assess the efficacy of decompressive craniectomy in patients with large basal ganglia (BG) bleed. To establish predictive criteria of mortality after surgery in patients with BG bleed.

Materials: This prospective study includes all patients of large spontane...

Abstract Read Full Article HTML

2021-04-26 Research Article

Endovascular treatment experience in acute ischemic stroke

Hacı Ali Erdoğan, İbrahim Acır* and Vildan Yayla


Background and Objective: Thrombolytic and mechanical thrombectomy therapies are proven treatment methods in patients with acute stroke. Aim is to share our experience in acute stroke therapy with colleagues.

Material and methods: In this study we evaluated the pati...

Abstract Read Full Article HTML DOI: 10.29328/journal.jnnd.1001047 Cite this Article

2021-04-20 Research Article

Characterization of the immune response in neuroimmune disorders in children

Nicolas Chiriboga, Jennifer Muñoz-Pareja and Jose Irazuzta*


Background: A misguided auto-reactive injury is responsible for several types of central nervous system (CNS) conditions in pediatrics. We propose that, in some of these conditions, the adaptive immune system has a common cellular immune pathogenesis, driven predominantly by ...

Abstract Read Full Article HTML DOI: 10.29328/journal.jnnd.1001046 Cite this Article

2021-03-23 Review Article

Cortical spreading depolarizations in the context of subarachnoid hemorrhage and the role of ketamine

Leandro Custódio do Amaral*


Delayed cerebral ischemia (DCI) is one of the main complications of spontaneous subarachnoid haemorrhage and one of its causes is the cortical spreading depolarizations (CSDs). Cortical spreading depolarizations are waves of neuronal and glial depolarizations in which there i...

Abstract Read Full Article HTML DOI: 10.29328/journal.jnnd.1001045 Cite this Article