Volume 1 Issue 1

2017-07-25 Review Article

The advances and challenges of Gene Therapy for Duchenne Muscular Dystrophy

Since the discovery of the dystrophin gene (DMD gene) thirty years ago, several therapeutic approaches have been investigated to treat Duchenne muscular dystrophy (DMD). This includes cell therapy, exon jumping, exonic knockout, and the CinDel method. In this article, we present the challenges...

Read Full Article HTML DOI: 10.29328/journal.jgmgt.1001003 Citation

2017-07-24 Mini Review

Progress in the development of Lipoplex and Polyplex modifi ed with Anionic Polymer for effi cient Gene Delivery

Nucleic acid-based therapy has become an increasingly important strategy for treating a variety of human diseases. In systemic therapy, a therapeutic gene must be delivered efficiently to its target tissues without side effects. To deliver a therapeutic gene such as plasmid DNA (pDNA) or small...

Read Full Article HTML DOI: 10.29328/journal.jgmgt.1001002 Citation

2017-06-23 Editorial

CRISPR genome editing: A general view

CRISPR technology has presented a path forward for genomic engineering and gene modification. The framework for the use of CRISPR technology to manipulate the human genome is of great interest and the form of its development and application has excited the researchers and biotech communities a...

Read Full Article HTML DOI: 10.29328/journal.jgmgt.1001001 Citation

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