Genes are those entities that determine our unique personalities. Genes do not only determine the way we look but also the way our body functions. Genetic medicine facilitates the development of genetic knowledge and its medical applications, while improving society understanding of genetics. Gene therapy is considered as an experimental technique that uses genes in treatment or prevention of diseases. Genetic medi... Readmore

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Wei Wu

Wei Wu | Editor-in-Chief

Associate Department Chair, Department of Toxicology, Nanjing Medical University,  China, Email:


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Recent Articles

2021-03-25 Research Article

Partial SHOX duplications associated with various cases of congenital uterovaginal aplasia (MRKH syndrome): A tangible evidence but a puzzling mechanism

Daniel Guerrier* and Karine Morcel


The Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is the most severe form of congenital malformation of the inner female reproductive tract. It is diagnosed as such when the uterus, the upper vagina and optionally the Fallopian tubes are absent. It accounts for approxim...

Abstract Read Full Article HTML DOI: 10.29328/journal.jgmgt.1001006 Cite this Article

2020-04-28 Research Article

Reasons why new coronavirus, SARS-CoV-2 infections are likely to spread

Takuma Hayashi*, Takashi Ura, Kaoru Abiko, Masaki Mandan, Nobuo Yaegashi and Ikuo Konishi

The ongoing outbreak of Coronavirus Disease 2019 (COVID-19) originally emerged in China during December 2019 and had become a global pandemic by March 2020. COVID-19 is caused by a novel coronavirus, severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2). Two other coronaviruses have c...

Abstract Read Full Article HTML DOI: 10.29328/journal.jgmgt.1001005 Cite this Article

2019-02-22 Review Article

The role of genetic mutations in genes LMNA, PPARG, PLIN1, AKT2, CIDEC in Kobberling–Dunnigan Syndrome

Shahin Asadi* and Mahsa Jamali


Köbberling-Dunnigan syndrome, also known as partial familial lipodystrophy, is a rare genetic disorder characterized by abnormal distribution of adipose tissues. Many people with Köbberling-Dunnigan syndrome develop insulin resistance, a condition in which body tiss...

Abstract Read Full Article HTML DOI: 10.29328/journal.jgmgt.1001004 Cite this Article

2017-07-25 Review Article

The advances and challenges of Gene Therapy for Duchenne Muscular Dystrophy

Jean-Paul Iyombe-Engembe and Jacques P Tremblay*


Since the discovery of the dystrophin gene (DMD gene) thirty years ago, several therapeutic approaches have been investigated to treat Duchenne muscular dystrophy (DMD). This includes cell therapy, exon jumping, exonic knockout, and the CinDel method. In this article, we pres...

Abstract Read Full Article HTML DOI: 10.29328/journal.jgmgt.1001003 Cite this Article

2017-07-24 Mini Review

Progress in the development of Lipoplex and Polyplex modifi ed with Anionic Polymer for effi cient Gene Delivery

Yoshiyuki Hattori*


Nucleic acid-based therapy has become an increasingly important strategy for treating a variety of human diseases. In systemic therapy, a therapeutic gene must be delivered efficiently to its target tissues without side effects. To deliver a therapeutic gene such as plasmid D...

Abstract Read Full Article HTML DOI: 10.29328/journal.jgmgt.1001002 Cite this Article

2017-06-23 Editorial

CRISPR genome editing: A general view

Ram Mohan Ram Kumar*


CRISPR technology has presented a path forward for genomic engineering and gene modification. The framework for the use of CRISPR technology to manipulate the human genome is of great interest and the form of its development and application has excited the researchers and bi...

Abstract Read Full Article HTML DOI: 10.29328/journal.jgmgt.1001001 Cite this Article