Genes are those entities that determine our unique personalities. Genes do not only determine the way we look but also the way our body functions. Genetic medicine facilitates the development of genetic knowledge and its medical applications, while improving society understanding of genetics. Gene therapy is considered as an experimental technique that uses genes in treatment or prevention of diseases. Genetic medi... Readmore

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Wei Wu

Wei Wu | Editor-in-Chief

Associate Department Chair, Department of Toxicology, Nanjing Medical University,  China, Email:

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Recent Articles

2019-02-22 Review Article

The role of genetic mutations in genes LMNA, PPARG, PLIN1, AKT2, CIDEC in Kobberling–Dunnigan Syndrome

Shahin Asadi* and Mahsa Jamali

Köbberling-Dunnigan syndrome, also known as partial familial lipodystrophy, is a rare genetic disorder characterized by abnormal distribution of adipose tissues. Many people with Köbberling-Dunnigan syndrome develop insulin resistance, a condition in which body tissues cannot adequat...

Read Full Article HTML DOI: 10.29328/journal.jgmgt.1001004 Citation

2017-07-25 Review Article

The advances and challenges of Gene Therapy for Duchenne Muscular Dystrophy

Jean-Paul Iyombe-Engembe and Jacques P Tremblay*

Since the discovery of the dystrophin gene (DMD gene) thirty years ago, several therapeutic approaches have been investigated to treat Duchenne muscular dystrophy (DMD). This includes cell therapy, exon jumping, exonic knockout, and the CinDel method. In this article, we present the challenges...

Read Full Article HTML DOI: 10.29328/journal.jgmgt.1001003 Citation

2017-07-24 Mini Review

Progress in the development of Lipoplex and Polyplex modifi ed with Anionic Polymer for effi cient Gene Delivery

Yoshiyuki Hattori*

Nucleic acid-based therapy has become an increasingly important strategy for treating a variety of human diseases. In systemic therapy, a therapeutic gene must be delivered efficiently to its target tissues without side effects. To deliver a therapeutic gene such as plasmid DNA (pDNA) or small...

Read Full Article HTML DOI: 10.29328/journal.jgmgt.1001002 Citation

2017-06-23 Editorial

CRISPR genome editing: A general view

Ram Mohan Ram Kumar*

CRISPR technology has presented a path forward for genomic engineering and gene modification. The framework for the use of CRISPR technology to manipulate the human genome is of great interest and the form of its development and application has excited the researchers and biotech communities a...

Read Full Article HTML DOI: 10.29328/journal.jgmgt.1001001 Citation