Clinical Nephrology is a specialty of medicine that concerns itself with the study of normal kidney function, kidney problems, the treatment of kidney problems and renal replacement therapy including dialysis and kidney transplantation.

The Journal of Clinical Nephrology is an initiative of Heighten Science Publication to publish distinctive and scholarly manuscripts that can play astounding role in enhancing the excellence and confidence of the doctors, scientists and researchers associated in the studies related to renal medicine, hypertension and other related fields of Clinical Nephrology.

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Recent Articles

2020-09-11 Research Article

Acute kidney injury in colombian patients with COVID-19 who received kidney support therapy with genius® 90 technology

Emilio Rey-Vela, Jesús Muñoz, Jorge Rico-Fontalvo, Rodrigo Daza-Arnedo, Katherin Portela-Buelvas, Nehomar Pájaro-Galvis, Víctor Leal-Martínez, Emilio Abuabara-Franco, José Cabrales-Juan, Leonardo Marín, Lucas Daza, Samuel Cuadro, Emir Ortiz, María Raad-Sarabia, Cesar Ferrer, Alejandra Prada, Greisy González, Elkin Mendoza, Klearly Tinoco, Jorge Camacho, Joel Ortega, Carlos Tobón, Juan Montes, Jorge Coronado, Luis Salgado-Montiel, José Correa, Fabio Salas, Amilkar Almanza-Hurtado and Miguel Aguilar-Schorborg


Introduction: Acute kidney injury (AKI) is one of the complications associated with severe COVID-19 infection, and it can present in up to 20% to 40% of the cases; of these, approximately 20% will require renal replacement therapy (RRT).


Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001059 Cite this Article

2020-08-21 Review Article

SGLT2 Inhibitors and nephroprotection in diabetic kidney disease: From mechanisms of action to the latest evidence in the literature

Jorge Rico-Fontalvo, Rodrigo Daza-Arnedo, Maria Ximena Cardona-Blanco, Victor Leal-Martínez, Emilio Abuabara-Franco, Nehomar Pajaro-Galvis, Jose Cabrales, José Correa, Manuel Cueto, Amable Duran, Alejandro Castellanos, Javier Enamorado, José Bohórquez, Isabella Uparella, Julio Zuñiga, Abraham Chagui, Alfonso Ramos and Luis Lara


Type 2 Diabetes Mellitus constitutes a major problem in public health worldwide. The disease poses a high risk of severe microvascular and macrovascular complications. Diabetic kidney disease is the most common cause of end-stage chronic kidney disease and contributes to the i...

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001058 Cite this Article

2020-07-28 Research Article

Correlation between interdialytic weight gain, left ventricular hypertrophy and FGF- 23 in prevalent hemodialysis patients

Sahar Mahmoud Shawky, Maha Mohamed Mohamed Khalifa*, Kholoud Mahmoud Amin and Mohamed Saeed Hassan


Background: Patients with end-stage renal disease are suspected to have significant volume shifts and thereby cardiovascular strain as a result to interdialytic weight gain, chronic fluid overload and fluid removal during dialysis. In long-term hemodialysis p...

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001057 Cite this Article

2020-07-20 Review Article

Biomarkers in acute kidney injury

Nehomar Pajaro Galvis*, Jorge Rico-Fontalvo, Rodrigo Daza-Arnedo, Maria Ximena Cardona-Blanco, Emilio Abuabara-Franco, Victor Leal-Martínez, Jose Cabrales-Juan, José Correa-Guerrero, José Bohórquez-Rivero, José Sáenz-López, José Restom-Arrieta, Milton Rivera-Moreno, Estefany Rivera-Moreno, Maria Monterrosa-Robles, Alonso Pomares-Lara, Dayana Ayola-Rosales and Ana Alonso-Henriquez


Acute kidney injury is a common condition associated with high morbidity and short-term mortality. Its pathophysiology varies according to the numerous conditions associated with its genesis. Biomarkers allow detecting changes at the level of kidney function; therefore, they ...

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001056 Cite this Article

2020-06-17 Case Report

Specific meningoencephalitis in patients with transplanted kidney

Mithat Tabakovic*, Senaid Trnacevic and Maida Dugonjic Taletovic


We described a case of specific (tuberculous) encephalitis in a patient after kidney transplantation. Immunosuppressive therapy, continuously required in post-tranplant period, may cause various complications, such as infections. Specific meningoencephalitis is an infection t...

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001055 Cite this Article

2020-06-05 Review Article

How does urine pH effect the tooth decay?

Muhammad Imran Qadir and Yasmeen Mureed*


The basic aim of the present study was to relate tooth decay with the pH of the urine. pH is very important aspect which affects and depends upon the urine specificity .The glomerulus is a necessary part in the structure of kidney .The glomerulus is involved in the filtration...

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001054 Cite this Article

2020-04-13 Research Article

Persistent hydronephrosis after pyeloplasty: Is it a true obstruction? The role of endourology

Ermelinda Mele, Michele Innocenzi, Laura Del Prete and Nicola Capozza*


Introduction: Anderson-Hynes pyeloplasty remains the gold standard in the treatment of ureteropelvic junction obstruction. The diagnostic criteria for defining the failure of pyeloplasty are not well-defined or even arbitrary. Likewise, the ideal treatment of...

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001052 Cite this Article

2020-04-13 Letter to the Editor

Meanings of microalbuminuria in idiopathic nephrotic syndrome in children

Richard Loumingou*


We investigated the existence of microalbuminuria in children with corticosteroid-sensitive idiopathic nephrotic syndrome in complete remission. In the study of a series of 18 cases, we noted a clearly different evolution depending on the existence or absence of pathological ...

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001051 Cite this Article

2020-02-26 Case Report

A remote cause of anuria in a child

Mehtap Çelakıl*, Zelal Ekinci and Kürşat Demir Yıldız


Acute renal injury is a rare complication of idiopathic nephrotic syndrome with mesPGN. Here we present a 2-year-old male patient with 4 days history of anuria, generalized edema and hypervolemia. Any evidence other than proteinuria and renal failure could not be identified w...

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001050 Cite this Article