Introduction

Clinical Nephrology is a specialty of medicine that concerns itself with the study of normal kidney function, kidney problems, the treatment of kidney problems and renal replacement therapy including dialysis and kidney transplantation.

The Journal of Clinical Nephrology is an initiative of Heighten Science Publication to publish distinctive and scholarly manuscripts that can play astounding role in enhancing the excellence and confidence of the doctors, scientists and researchers associated in the studies related to renal medicine, hypertension and other related fields of Clinical Nephrology.

Reasons for Publishing

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Articles

We publish a wide range of article types in the Clinical, Medical, Biology, Engineering, Chemistry and Pharma.

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Recent Articles

2021-07-23 Research Article

Practice patterns and outcomes of repository corticotropin injection (Acthar® Gel) use in childhood nephrotic syndrome: A study of the North American Pediatric Renal Trials and collaborative studies and the Pediatric Nephrology Research Consortium

Mohammed K Faizan*, Courtney McCracken, Kenneth Lieberman, Traci Leong and Mark R Benfield

Summary

Objective: We set up a U.S. registry to examine prescription patterns and patient outcomes of repository corticotropin injection (Acthar® Gel) for childhood nephrotic syndrome.

Methods: 18 participating U.S. pediatric centers performed retrospective review and pr...

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001077 Cite this Article

2021-07-21 Research Article

Multifrecuency bioimpedance phase angle as a tool to predict maturation failure of native fistulae for hemodialysis

José Lucas Daza Lopez*, John F Galindo, Mónica R Villaquiran, Emilio D Valenzuela, Andres Cardenas, Luis Jose Daza6, Maria Camila Correcha, Jonathan de Jong, Yaroslad De La Cruz Prieto, Gerardo Gutierrez and Luis Puello

Summary

Background and objectives: An arteriovenous fistula is considered to be an ideal vascular access for patients receiving hemodialysis, its main limitation is its high failure rate to achieve maturation and long-term functionality loss. Multiple strategies have attempted to iden...

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2021-07-20 Research Article

Usefulness of foot-to-foot bioimpedance analysis for assessing volume status in chronic hemodialysis patients at the Aristide Le Dantec University Hospital (Senegal)

Niakhaleen Keita*, Maria Faye, Sidy Mouhamed Seck, Boucar Ndong, Moustapha Faye, Ahmed Tall Lemrabott, Bacary Ba, Seynabou Diagne1, Mansour Mbengue, Ameth Dieng, Mamadou Aw Ba, Abdou Sy, Modou Ndongo, Babacar Ndiaye and Elhadji Fary Ka

Summary

Introduction: Determination of dry weight is one of the daily goals to achieve in hemodialysis. The aim of this study was to validate the use of bioelectrical impedance analysis (BIA) in estimation of dry weight in a population of Senegalese chronic hemodialysis patients.

...

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2021-07-14 Case Report

Acute Kidney Injury due to spontaneous Atheroembolic disease, superimposed on diabetic nephropathy, with no recent vascular or cardiac intervention, presented as Rapidly Progressive Glomerulonephritis (RPGN)

Anas Diab*, Parravani Anthony, Hollie Berryman and Kareem Diab

Atheroembolic disease (AED), or Cholesterol Crystals Embolism, is a systemic disease presented as a complication of severe atherosclerosis [1], where older age, male sex, diabetes hypercholesterolemia, smoking and hypertension [2], are the main risk factors for the development of  Atheroscle...

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2021-05-05 Research Article

Impact of a multidisciplinary pre-dialysis program on renal treatment modalities choice

Luis Miguel Castro Fonseca dos Santos Oliveira*, Rui Arlindo dos Santos Alves de Castro and Teresa Margarida Ribeiro Pinto Morgado

In Portugal, around 2500 patients with end-stage chronic kidney disease (CKD stage 5) start a renal replacement therapy (RRT) for the first time each year [1]. They have four main treatment options: kidney transplantation (TX); haemodialysis (HD); peritoneal dialysis (PD) and conservative treatme...

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001073 Cite this Article

2021-04-27 Research Article

Nonlinear relationship between blood glucose and 30-day mortality in critical patients with acute kidney injury: A retrospective cohort study

Qilin Yang, Weichao Huang, Xiaomei Zeng, Jiezhao Zheng, Weixiao Chen and Deliang Wen*

Abstract

Background: Acute kidney injury (AKI) is a major health problem affecting millions of people worldwide. Effective preventative and therapeutic treatments remain to be produced. We aim to determine the association between blood glucose and mortality in critical patients with A...

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001072 Cite this Article

2021-04-27 Research Article

Prognostic factors for chronic kidney disease and end-stage renal disease in patients with lupus nephritis: A retrospective cohort study

Fernanda Nogueira Holanda Ferreira Braga*, Marta Maria das Chagas Medeiros, Antônio Brazil Viana Jr., Levi Coelho Maia Barros, Marcelo Ximenes Pontes, Matheus Eugênio de Sousa Lima, Allyson Wosley de Sousa Lima and Paula Frassinetti Castelo Branco Camurça Fernandes

Abstract

Background: Lupus Nephritis (LN) occurs in approximately half of all patients with Systemic Lupus Erythematosus (SLE) and it is the most common cause of morbidity and mortality in patients with SLE. Factors associated with poor renal outcome vary among studies, and researches...

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001071 Cite this Article

2021-04-22 Case Report

Diffuse alveolar hemorrhage: Unusual presentation of systemic lupus erythematosus

Zajjari Yassir*, Sobhi Aya, Aatif Taoufiq, Azizi Mounia and El Kabbaj Driss

Diffuse alveolar hemorrhage (DAH) is a rare complication of systemic lupus erythematosus (SLE) and carries a high mortality.

It was first described by Osler in 1904 as the most devastating pulmonary complication of SLE.

We describe a case of a 23-year-old girl recently diagnos...

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001070 Cite this Article

2021-04-08 Research Article

Collecting duct PGE2 responses reduce water loss with empagliflozin in mice with type 2 diabetes mellitus

R Nasrallah, J Zimpelmann, V Cheff, JF Thibodeau, KD Burns and RL Hébert*

Abstract

Introduction: Sodium-glucose cotransporter 2 inhibitors such as empagliflozin (EMPA) protect against diabetic kidney disease. Prostaglandin E2 (PGE2) the main renal product of cyclooxygenase-2, inhibits vasopressin (AVP)-water reabsorption in the collecting duct (CD). The nov...

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001069 Cite this Article

2021-03-08 Case Report

Prostate cancer-associated thrombotic microangiopathy: A case report and review of the literature

HHS Kharagjitsing*, PAW te Boekhorst and Nazik Durdu-Rayman

Abstract

Background: Thrombotic microangiopathy (TMA) is a rare and life-threatening complication of prostate carcinoma. Whether plasma exchange has a role in treatment remains a subject of debate. Here we present a case followed by a systematic review of the literature on this subjec...

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001068 Cite this Article