Volume 1 Issue 1

Research Article

Association between bh4/bh2 ratio and Albuminuria in Hypertensive Type -2 Diabetic patients

Endothelial dysfunction and inflammation play a key role in the pathophysiology of diabetic nephropathy; Tetrahydrobiopterin (BH4) is an essential cofactor for nitric oxide synthase, when BH4 is reduced to dihydrobiopterin (BH2), endothelial dysfunction is induced.

Read Full Article HTML DOI: 10.29328/journal.jcn.1001009 Citation Views: 3440


Short term effect of Intravenous Intermittent Iron Infusion versus Bolus Iron Infusion on Iron parameters in Hemodialysis patients

Intravenous iron is used in combination with erythropoi esis-stimulating agents to treat the anemia of hemodialysis patients, however, there is variety in the dose and the frequency.

Read Full Article HTML DOI: 10.29328/journal.jcn.1001008 Citation Views: 1052

Research Article

The outcome of Acute Kidney Injury in patients with severe Malaria

Background: Acute kidney injury (AKI) is a frequent and serious clinical complication in patients with severe malaria.

Read Full Article HTML DOI: 10.29328/journal.jcn.1001007 Citation Views: 4422

Research Article

Anemia response to Methoxy Polyethylene Glycol-Epoetin Beta (Mircera) versus Epoetin Alfa (Eprex) in patients with chronic Kidney disease on Hemodialysis

Objective: Anemia, a common complication of chronic kidney disease, usually develops because of erythropoietin defi ciency. Maintaining target hemoglobin (Hb) with minimal variability is a challenge in hemodialysis (HD) patients. The aim of this study is to compare the long- a...

Read Full Article HTML DOI: 10.29328/journal.jcn.1001006 Citation Views: 4011

Research Article

Profile of vitamin D receptor polymorphism Bsm I and FokI in end stage renal disease Egyptian patients on maintenance hemodialysis

Objective: In end stage renal disease, the synthesis of vitamin D is disturbed. Hyperparathyroidism is one of the key factors in the pathogenesis of many of the complications of dialysis mainly bone and cardiovascular complications

Read Full Article HTML DOI: 10.29328/journal.jcn.1001005 Citation Views: 4423

Case Report

Acute Tubulointerstitial Nephritis due to Phenytoin: Case Report

Introduction: Acute tubulointerstitial nephritis (ATIN) is an acute kidney injury (AKI) resulting from damage to the tubulointerstitial tissue due to infection, trauma, or use of medication. It is clinically non-specific.

Read Full Article HTML DOI: 10.29328/journal.jcn.1001004 Citation Views: 4825

Research Article

Intraperitoneal and Subsequent Intravenous Vancomycin: An Effective Treatment Option for Gram-Positive Peritonitis in Peritoneal Dialysis

Intraperitoneal vancomycin absorption is higher when there is peritoneal infl ammation, but the absorption decreases with recovery from peritonitis. Consequently, intraperitoneal maintenance doses are ineffective, reducing the rate of cure.

Read Full Article HTML DOI: 10.29328/journal.jcn.1001003 Citation Views: 4941

Short Communication

Cardiac Manifestations on Anti- Phospholipid Syndrome

Antiphospholipid syndrome may present in various ways from cutaneous manifestation, obstetric complications, neurological manifestation, and cardiac manifestation to renal involvement. There are many cardiac complication of anti-phospholipid syndrome, among them are valvular dysfunction, pulmo...

Read Full Article HTML DOI: 10.29328/journal.jcn.1001002 Citation Views: 2328

Case Report

The Risk-Adjusted Impact of Intraoperative Hemofi ltration on Real-World Outcomes of Patients Undergoing Cardiac Surgery

Objectives: The role of perioperative hemofiltration (HF) in adult patients with impaired renal function undergoing cardiac surgery ...

Read Full Article HTML DOI: 10.29328/journal.jcn.1001001 Citation Views: 4521