Clinical Nephrology is a specialty of medicine that concerns itself with the study of normal kidney function, kidney problems, the treatment of kidney problems and renal replacement therapy including dialysis and kidney transplantation.

The Journal of Clinical Nephrology is an initiative of Heighten Science Publication to publish distinctive and scholarly manuscripts that can play astounding role in enhancing the excellence and confidence of the doctors, scientists and researchers associated in the studies related to renal medicine, hypertension and other related fields of Clinical Nephrology.

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Recent Articles

2021-01-20 Clinical Image


Hyperacute fatal course in a hypercalcemic crisis

Sara Turco*, Alice Chiara Manetti, Aniello Maiese, Matteo Scopetti and Marco Di Paolo

Clinical Image

A 39-year-old woman, with a not significant past medical history, entered the Emergency Department complaining about nausea, vomiting, constipation, anorexia, deep asthenia, and diffuse muscle aches with cramps. She referred sporadic diarrhea (one episode) the day befor…

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001066 Cite this Article

2021-01-12 Research Article


Glomerular hyperfiltration in Yemeni children with sickle cell disease

Abdul-Wahab M Al-Saqladi* and Fatima E Al-Musawa


Background: Glomerular hyperfiltration (GH) is a common feature of sickle cell nephropathy (SCN) starting at infancy and represents an early marker of incipient glomerular injury and renal dysfunction.

Methods: This study aimed to determine the prevalence and correl…

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001065 Cite this Article

2020-12-24 Case Report


Stroke vs. SIADH: A case of symptomatic hyponatremia secondary to SIADH in association with COVID-19 infection

Shadi Bagherzadeh, Siamak M Seraj and Amirhossein Afshar


A 66-year-old male with no known past medical history presented with history of two days of throbbing frontal headache associated with nausea, vomiting and left-sided facial droop. The patient also reported dizziness, subjective chills without cough, shortness of breath, or s…

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001064 Cite this Article

2020-11-04 Case Report


Unusual presentation of Oxalate nephropathy causing Acute Kidney Injury: A case report

Anas Diab*, Michelle M Neuman, Kareem Diab and Daniel Gordon


Oxalate Nephropathy due to Hyperoxaluria and elevated serum oxalate level is a well-known cause for interstitial fibrosis, and ESRD. Conditions associated with high serum Oxalate, should be considered as a possible contributing factor for a patient’s tubular injury,

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001063 Cite this Article

2020-11-02 Research Article


Modification of the Renal Angina Index for identifying the need for renal replacement therapy in critically ill pediatric patients

Erin K Stenson*, John T Brinton, Liz Beil, Danielle E Soranno4 and Katja M Gist

Severe Acute Kidney Injury (AKI) is a common, serious problem affecting critically ill children that lacks effective treatment options. Currently, there are no treatment options for AKI other than supportive care. Continuous renal replacement therapy (CRRT) is employed to reduce Fluid Overload (F…

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001062 Cite this Article

2020-10-20 Case Report


COVID-19 related rhabdomyolysis

Alejandro Munoz-Martinez, Maham Akbar Waheed, Kenar D Jhaveri and Geurys Rojas-Marte*

A novel coronavirus known as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) with a high rate of human-to-human transmission has emerged, resulting in a worldwide public health crisis of catastrophic proportions. Common initial symptoms of Coronavirus Disease 2019 (COVID-19) include …

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001061 Cite this Article

2020-10-02 Research Article


Frequency of renal tubular acidosis in children with down syndrome

Silvestre García de la Puente*, Karla Adney Flores Arizmendi, Junior Rafael Gahona Villegas, Paola Andrea Yepes Genoy and Elena Lissette Garza Guerrero


Background: Down syndrome (DS) is associated with various congenital diseases and malformations, including those of the kidneys and urinary tract. It has been thought that renal tubular acidosis (RTA) is more frequent in this population. The objective of this study was to ass…

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001060 Cite this Article

2020-09-11 Research Article


Acute kidney injury in colombian patients with COVID-19 who received kidney support therapy with genius® 90 technology

Emilio Rey-Vela, Jesús Muñoz, Jorge Rico-Fontalvo, Rodrigo Daza-Arnedo, Katherin Portela-Buelvas, Nehomar Pájaro-Galvis, Víctor Leal-Martínez, Emilio Abuabara-Franco, José Cabrales-Juan, Leonardo Marín, Lucas Daza, Samuel Cuadro, Emir Ortiz, María Raad-Sarabia, Cesar Ferrer, Alejandra Prada, Greisy González, Elkin Mendoza, Klearly Tinoco, Jorge Camacho, Joel Ortega, Carlos Tobón, Juan Montes, Jorge Coronado, Luis Salgado-Montiel, José Correa, Fabio Salas, Amilkar Almanza-Hurtado and Miguel Aguilar-Schorborg


Introduction:  Acute kidney injury (AKI) is one of the complications associated with severe COVID-19 infection, and it can present in up to 20% to 40% of the cases; of these, approximately 20% will require renal replacement therapy (RRT).

Objective: …

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001059 Cite this Article

2020-08-21 Review Article


SGLT2 Inhibitors and nephroprotection in diabetic kidney disease: From mechanisms of action to the latest evidence in the literature

Jorge Rico-Fontalvo, Rodrigo Daza-Arnedo, Maria Ximena Cardona-Blanco, Victor Leal-Martínez, Emilio Abuabara-Franco, Nehomar Pajaro-Galvis, Jose Cabrales, José Correa, Manuel Cueto, Amable Duran, Alejandro Castellanos, Javier Enamorado, José Bohórquez, Isabella Uparella, Julio Zuñiga, Abraham Chagui, Alfonso Ramos and Luis Lara


Type 2 Diabetes Mellitus constitutes a major problem in public health worldwide. The disease poses a high risk of severe microvascular and macrovascular complications. Diabetic kidney disease is the most common cause of end-stage chronic kidney disease and contributes to the i…

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001058 Cite this Article

2020-07-28 Research Article


Correlation between interdialytic weight gain, left ventricular hypertrophy and FGF- 23 in prevalent hemodialysis patients

Sahar Mahmoud Shawky, Maha Mohamed Mohamed Khalifa*, Kholoud Mahmoud Amin and Mohamed Saeed Hassan


Background: Patients with end-stage renal disease are suspected to have significant volume shifts and thereby cardiovascular strain as a result to interdialytic weight gain, chronic fluid overload and fluid removal during dialysis. In long-term hemodialysis p…

Abstract Read Full Article HTML DOI: 10.29328/journal.jcn.1001057 Cite this Article