Volume 4 Issue 1

2019-12-12 Case Report

Embolic Septic Emboli with MRSA: A different source


Septic Iliac vein thrombophlebitis with associated psoas abscess is a rare and severe entity, which diagnosis is challenging when no risk factor is clearly present. We are presenting a case of severe septic cavitary pulmonary emboli complicated with Acute Respiratory Distress Syndrome (ARDS) that evolved rapidly to respiratory distress and multi organ failure.
A 61-year-old Hispanic male, had multiple emergency department visits due to back pain, being most of them intramuscular pain medications and steroids. In the history, he had back pain that worsened accompanied by poor mobility, generalized malaise, fever and chills. Computed tomography (CT) scan showed a paravertebral psoas abscess with L5 - S1 diskitis/spondylitis inflammatory changes, which was then later evidenced by a gallium study. Further imaging studies were done, showed bilateral cavitary lung lesions, consistent with septic emboli. Subsequent blood cultures were positive for Methicillin Resistant Staphylococcus Aureus (MRSA), for which a successful combined therapeutic regimen was used. Transthoracic and transesophageal echocardiogram were not suggestive of endocarditis. Staphylococcus aureus (SA) bacteremia is one of the most common serious bacterial infections with a high risk of metastatic complications, which makes this pathogen a unique one. The combination of factors iliac vein thrombophlebitis, psoas muscle abscess, diskitis/spondylitis with ARDS makes cavitary pulmonary disease a challenging perspective. After a 6-week antimicrobial treatment, full anticoagulation, his clinical condition and image findings improved, and he was recently admitted for physical rehabilitation. Major vessels thrombophlebitis should always be considered, when primary source of septic pulmonary emboli is not clear. This case illustrates the complexity of illness and complications that may arise from a source of infection as the one in this patient. Further therapeutic strategies were tailored accordingly.

Abstract Read Full Article HTML DOI: 10.29328/journal.jcicm.1001026 Cite this Article

2019-12-09 Case Report

Brainstem Death due to hypertension induced brain hemorrhage


Brain stem death is when a person has permanently lost the potential for consciousness and the capacity to breathe. When this happens, a machine called a ventilator keeps oxygen circulating through the person’s bloodstream - a person confirmed as being dead when their brain stem function is permanently lost [1].

Abstract Read Full Article HTML DOI: 10.29328/journal.jcicm.1001025 Cite this Article

2019-08-22 Review Article

Management of Ischemic Stroke during cardiac catheterization: A case report and review of literature


Stroke following coronary interventions is a devastating and most dreaded complication with signiβicant morbidity and mortality. Various factors have been ascribed for this complication including the technical errors [1]. A small percentage of strokes are iatrogenic, including those associated with invasive cardiac procedures. According to the literature, it is a rare complication of left heart catheterization [2]. Percutaneous coronary intervention is increasingly used to treat patients with diffuse atherosclerosis, acute coronary syndromes and even high-risk patients such as low ejection fraction [1]. The authors describe a patient who underwent percutaneous coronary intervention in the context of inferior infarction, which was complicated by ischemic stroke during cardic catheterization.

Abstract Read Full Article HTML DOI: 10.29328/journal.jcicm.1001024 Cite this Article

2019-07-22 Review Article

Update on Phenobarbital for Alcohol Withdrawal Syndrome in Intensive Care


Alcohol abuse is a global health problem. Alcohol withdrawal syndrome (AWS) ranges from mild to severe symptoms that can lead to fatal delirium tremens requiring ICU admission and incurring high health care cost as high as $20,000 a month. The latest published reports suggest that phenobarbital is a promising therapeutic option for management of AWS as evidenced by less ICU admissions, length of stay in hospital, use of adjunctive agents, health care costs and attention from the nursing staff than that of patients treated with commonly used benzodiazepines such as lorazepam, diazepam, and chlordiazepoxide. Phenobarbital is beneficial for the treatment of AWS, both in the emergency and inpatient settings and both as monotherapy or in conjunction with benzodiazepines. It is safe for patients without severe hepatic impairment, has a better mechanism of action and longer half-life than benzodiazepines, and leads to less delirium and agitation. Powered randomized controlled trials with large populations are required, yet phenobarbital can be used to safely to treat AWS.

Abstract Read Full Article HTML DOI: 10.29328/journal.jcicm.1001023 Cite this Article

2019-04-19 Letter to the Editor

Do you really want to improve the results of treatment for acute pneumonia?

Letter to the Editor

The question raised in the title of this letter is a natural consequence of the findings and conclusions that have been growing steadily in recent years regarding the results of treatment for acute pneumonia (АР). If you look at the publications of recent years in this field of medicine, it turns out that one of the main obstacles to progress in improving the results of treatment of this disease is the lack of appropriate methods for determining the pathogen. Thus, the lack of timely diagnostic information about the etiology of the disease excludes the possibility of targeted antibiotic therapy. In recent years, such regrets have become more and more relevant, playing the role of the main explanation for treatment failures .Continuing to narrow the unidirectional view of the problem and to pay attention only to the microbial factor as the main cause of the disease, such views are in fact another illusion, which, even in the case of its hypothetical implementation, will not make significant changes in the overall trend. This statement is easy to verify if you rely on well-known facts, and not use as arguments assumptions and guesses.

Abstract Read Full Article HTML DOI: 10.29328/journal.jcicm.1001021 Cite this Article

2019-02-07 Research Article

Angioarchitectonics of acute pneumonia


The article presents the results of x-ray anatomical studies of 56 whole lung preparations, which were carried out immediately after the autopsy of children who died from АP. In 47 cases it was carried out the contrast of the vessels and in 9 cases the bronchial tree. The results allowed to clarify some details of the pathogenesis of АP and were additional arguments in support of the new doctrine of the disease.

Abstract Read Full Article HTML DOI: 10.29328/journal.jcicm.1001020 Cite this Article

2019-02-04 Research Article

Acute pneumonia: Facts and realities against etiological hypotheses and beliefs


Modern AP concepts are focused exclusively on the infectious nature of the disease and the presence of certain pathogens. This belief determines the principles of treatment, the lack of effectiveness of which remains a concern of health professionals. The article presents a fragment of the study devoted to the etiology of АP. 994 children aged 4 months to 14 years with various forms of so-called community-acquired pneumonia were examined and treated. Bacteriological examination of the material from the inflammation zone was carried out in 542 patients. Experiments on modeling АP and its pleural complications were performed on 44 animals. The obtained results and critical analysis of the literature data and scientific facts allow us to consider bacteria only as one of the etiological elements of АP, which is not mandatory in all cases of the disease. Scientifically based revision of existing ideas about the causes and mechanisms of AP development leads to the need for a radical change in the principles of treatment and is a strategic direction in solving the problem.

Abstract Read Full Article HTML DOI: 10.29328/journal.jcicm.1001019 Cite this Article

Recent Articles

2020-05-29 Short Review

Levosimendan in sepsis  

Ugur Koca* and Burcu Tanay Demirdöven

Abstract Read Full Article HTML DOI: 10.29328/journal.jcicm.1001030 Citation

2020-05-12 Research Article

DSM algorithm to determine the decentralized bases of the SAMU natal through the use of simulation

Eric Lucas dos Santos Cabral, Wilkson Ricardo Silva Castro, Davidson Rogério de Medeiros Florentino, João Florêncio da Costa Jr., Talita Dias Chagas Frazão, Claudia Aparecida Cavalheiro Francisco, Ricardo Pires de Souza, Amália Cinthia Meneses Rêgo, Irami Araújo Filho* and Marco Antônio Leandro Cabral

Abstract Read Full Article HTML

2019-12-12 Case Report

Embolic Septic Emboli with MRSA: A different source

Christian Castillo Latorre*, Mariela Rivera Agosto, Ilean Lamboy Hernandez, Mariana Mercader Perez, Dominic Sanchez Paredes, Marisol Santiago Irizarry, Jose Gutierrez Nuñez Onix, Cantres Fonseca, Alfonso Torres Palacios and William Rodriguez Cintron

Abstract Read Full Article HTML DOI: 10.29328/journal.jcicm.1001026 Citation

2019-08-22 Review Article

Management of Ischemic Stroke during cardiac catheterization: A case report and review of literature

Naoufal Chouaib*, Said Jidane, Mounir Lekhlit, Ahmed Belkouch, Tahir Nebhani, Saad Zidouh and Lahcen Belyamani

Abstract Read Full Article HTML DOI: 10.29328/journal.jcicm.1001024 Citation