The pharmaceutical sciences syndicate a comprehensive range of scientific disciplines that are critical to the innovating and improving new drugs and therapies. Pharmaceutical sciences can be largely classified into categories including drug discovery and design, drug delivery, drug action and clinical sciences.

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Kexin Liu

Kexin Liu | Editor-in-Chief

Clinical Pharmacology, Dalian Medical University, China, Tel: 13056788031; Email:

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Recent Articles

2019-12-11 Research Article

Co-extract mixture from Strophanthus hispidus (roots) and Aframomum meleguta (seeds) show phytochemical synergy in its anti-inflammatory activity

John Kenneth Mensah*, Amina Ibrahim and Yakubu Jibira


Background: Combination of extracts from multiple plants are typically used in ethnomedicine to putatively offer more potent chemotherapeutic and chemopreventive effects than that of individual extracts from single plants. Aqueous extracts from two multipurpo...

Abstract Read Full Article HTML DOI: 10.29328/journal.apps.1001019 Cite this Article

2019-12-10 Research Article

To legalize cannabis in Ghana or not to legalize? Reviewing the pharmacological evidence

Kwesi Boadu Mensah* and Paa Kofi Tawiah Adu-Gyamfi


Background: Although illegal, Ghana has a long history of cannabis use. With changing perceptions, advocacy for legalization has increased globally. This study exams pharmacological evidence on the prospects and challenges of decriminalization and /or legaliza...

Abstract Read Full Article HTML DOI: 10.29328/journal.apps.1001018 Cite this Article

2019-09-27 Research Article

Screening of antibiotic residue in poultry in Kathmandu valley of Nepal: A cross-sectional study

Rajiv Sapkota*, Ramila Raut, Sujan Khanal, Muna Gyawali and Dipesh Sahi

This cross-sectional study was conducted to screen the presence of antibiotic residue in poultry. A total of 60 samples (30 Muscle and 30 Liver) were taken from local meat shops from different parts of Kathmandu valley. Disc assay method was used. Escherichia coli (ATCC 25922) and Staphylococc...

Abstract Read Full Article HTML DOI: 10.29328/journal.apps.1001017 Cite this Article

2019-09-20 Research Article

The association between hypoxia, chronic ischemia and alters prostate structure and progress of chronic prostatic disease

Mauro Luisetto*, Behzad Nili Ahmadabadi, Ghulam Rasool Mashori, Gamal Abdul Hamid

Chronic prostatitis today show high level of relapses and recurrent pathological events even if using the best pharmacological therapy. A better understanding of physiopathological effect of ischemic hypoxic condition (pelvic, prostate tissue) and the lymphatic congestion in same body region c...

Abstract Read Full Article HTML DOI: 10.29328/journal.apps.1001016 Cite this Article

2019-08-15 Research Article

Discovering the right treatments for diabetes (2), blood’s pressure, and relating diseases

Alaa Hussein Al-Darraji*

For last decades diabetes type 2, blood’s pressure (especially hypertension) and relating diseases are most serious problems for much people over the world. These diseases are not like other different diseases then for studying them very accuracy, this research choose sample from different s...

Abstract Read Full Article HTML DOI: 10.29328/journal.apps.1001015 Cite this Article

2019-07-16 Research Article

The relationship between serum and sputum levels of azithromycin and clinical endpoints in patients with bronchiectasis using azithromycin maintenance treatment

Josje Altenburg*, Erik B Wilms and Wim G Boersma

Background: Azithromycin (AZM) is a macrolide antibiotic with distinct pharmacokinetic properties and is increasingly used as maintenance treatment in patients with bronchiectasis in order to reduce infectious exacerbations and improve pulmonary symptoms. The exact mechanism o...

Abstract Read Full Article HTML DOI: 10.29328/journal.apps.1001014 Cite this Article

2019-05-08 Review Article

Pharmacodynamics of cannabinoids

Alexandra Sulcova*

“Pharmacodynamics of cannabinoids “(i.e. a set of biological effects elicited in the living organism by interaction with its biochemical and biophysical functions up to the cellular level) is studied for a long time during both, physiological and pathological conditions.

Abstract Read Full Article HTML DOI: 10.29328/journal.apps.1001013 Cite this Article

2019-01-17 Research Article

Stepwise regression modeling on the monitoring of separation of Salvianolate through macroporous resin chromatographic column using UV spectral data

Yongsuo Liu*, Yong Wang and Guoan Luo

Aim: Study the monitoring method of separation of Salvianolate through macroporous resin chromatographic column using UV spectral data.

Method: HPLC was used to determine the concentration of Salviol B in the eluent liquid of macroporous resin chrom...

Abstract Read Full Article HTML DOI: 10.29328/journal.apps.1001012 Cite this Article

2018-10-30 Review Article

Application of the Pyphagor’s Theorem for Correction of Ki and Ka constants of enzyme inhibition and activation

VI Krupyanko* and PV Krupyanko

The analysis of dependence of the length projection of Li vectors of biparametrical inhibited and activated (La) enzymatic reactions from the length projection of vectors of monoparametrical inhibited and activated enzymatic reactions on the basic σ0 plane in three-dimensional coordinate syst...

Abstract Read Full Article HTML DOI: 10.29328/journal.apps.1001011 Cite this Article

2018-10-29 Research Article

Preclinical studies for a cationic liposome formulation containing Il-2 Intended for the treatment of Human Tumors

Maria Teresa Corona-Ortega*, Arturo Valle-Mendiola, Leonor Aguilar-Santelises, Araceli Garcia del Valle, Rosalva Rangel-Corona and Benny Weiss-Steider

Human cervical cancer tumours expressing the IL-2 receptor (IL-2R) were induced in the peritoneal cavity of nude mice. The tumours were significantly reduced by the i.p. administration of either free IL-2 or liposomes containing this growth factor. No toxicity was observed in the mice even at ...

Abstract Read Full Article HTML DOI: 10.29328/journal.apps.1001010 Cite this Article