Introduction

Proteomics is a rapidly growing field of molecular biology that is concerned with the methodical approach to protein expression analysis of a cell or an organism. Bioinformatics is the application of computer expertise to the management of biological information. The melding of science of Bioinformatics with proteomics provides an essential edge to the use of genomic information in understanding human diseases and ... Readmore

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We publish a wide range of article types in the Clinical, Medical, Biology, Engineering, Chemistry and Pharma.

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Recent Articles

2021-07-20 Research Article

The SARS CoV-2 spike domain, RGD and integrin binding effect-relationship for vaccine design strategy

Luisetto M*, Tarro G, Khaled Edbey, Almukthar N, Cabianca L, Mashori GR, Ahnaf Ilman, Yesvi AR and Latyschev OY

Abstract

Related the need to search new strategy in vaccine design in order to reduce also some rare effect like trombosys for some registered products it is interesting the role played by the SPIKE RGD domain.

The binding with molecules like Fibronectin is a process that mu...

Abstract Read Full Article HTML

2021-06-14 Review Article

Pigeonpea sterility mosaic virus a green plague-Current status of available drug and new potential targets

Nisha Singh*, Bhawna Narula, Megha Ujinwal and Sapna Langyan

Abstract

Pigeonpea is one of the important legume crops with high protein content and nutritional traits. It has enormous potency for its widespread adoption by farming communities. It is affected by various kinds of biotic and abiotic stresses. In the context, of biotic stresses Ster...

Abstract Read Full Article HTML DOI: 10.29328/journal.apb.1001013 Cite this Article

2021-04-08 Research Article

Role of toll-like receptors and their ligands in adipocyte secretion

A Mishra*, AV Shestopalov, AM Gaponov, IA Alexandrov and SA Roumiantsev

Abstract

Background: Adipose tissue is one of the main sites of energy homeostasis that regulates whole body metabolism with the help of adipokines. Disruption in its proper functioning results in adipose tissue remodeling (primarily hypertrophy and hyperplasia) which directly influen...

Abstract Read Full Article HTML DOI: 10.29328/journal.apb.1001012 Cite this Article

2020-07-03 Research Article

In silico comparative analysis of HIV protease inhibitors effect on 2019-nCoV coronavirus 3CLpro

Vandna Kumari and Shamsher Singh Kanwar*

Abstract

The novel coronavirus 2019-nCoV has become a bane to mankind and spread worldwide and infected many people. Thus, there is an urgent need of a cure for the severe pneumonia disease caused by this virus. In this study, in silico comparative analysis has been done for HIV prote...

Abstract Read Full Article HTML DOI: 10.29328/journal.apb.1001011 Cite this Article

2020-02-11 Research Article

Improving cancer diseases classification using a hybrid filter and wrapper feature subset selection

Noor Muhammed Noori* and Omar Saber Qasim

Abstract

In the classification of cancer data sets, we note that they contain a number of additional features that influence the classification accuracy. There are many evolutionary algorithms that are used to define the feature and reduce dimensional patterns such as the gray wolf al...

Abstract Read Full Article HTML DOI: 10.29328/journal.apb.1001010 Cite this Article

2020-01-30 Review Article

Classification of diseases using a hybrid fuzzy mutual information technique with binary bat algorithm

Firas Ahmed Yonis AL-Taie* and Omar Saber Qasim

Abstract

Genetic datasets have a large number of features that may significantly affect the disease classification process, especially datasets related to cancer diseases. Evolutionary algorithms (EA) are used to find the fastest and best way to perform these calculations, such as the...

Abstract Read Full Article HTML DOI: 10.29328/journal.apb.1001009 Cite this Article

2019-12-31 Research Article

The importance of gestational age in first trimester, maternal urine MALDI-Tof MS screening tests for Down Syndrome

Ray K Iles*, Nicolaides K, Pais RJ, Zmuidinaite R, Keshavarz S, Poon LCY and Butler SA

Abstract

Background: The proposal that MALDI-ToF mass spectrometry could be used as a direct, rapid and affordable diagnostic tool in clinical laboratory medicine has moved from a theoretical possibility to a reality for Microbiology. Several studies have proposed the...

Abstract Read Full Article HTML DOI: 10.29328/journal.apb.1001008 Cite this Article

2019-12-19 Research Article

Theoretical study on binding interactions of laccase-enzyme from Ganoderma weberianum with multiples ligand substrates with environmental impact

Yosberto Cárdenas-Moreno*, Luis Ariel Espinosa, Julio Cesar Vieyto, Michael González-Durruthy, Alberto del Monte-Martinez, Gilda Guerra-Rivera and Maria Isabel Sánchez López

Abstract

Laccase catalyzes oxidation of lignin and aromatic compound with similar structure to this one. Their low substrate specificity results on degradation of similar phenolic compounds. In this context, Molecular Docking was performed with different ligands suggesting potential b...

Abstract Read Full Article HTML DOI: 10.29328/journal.apb.1001007 Cite this Article

2018-04-09 Review Article

The properties of nonlinear excitations and verification of validity of theory of energy transport in the protein molecules

Pang Xiao-Feng*

Abstract

Based on different properties of structure of helical protein molecules some theories of bio-energy transport along the molecular chains have been proposed and established, where the energy is released by hydrolysis of adenosine triphosphate (ATP). A brief survey of past rese...

Abstract Read Full Article HTML DOI: 10.29328/journal.apb.1001006 Cite this Article

2018-03-02 Opinion

Prediction of protein Post-Translational Modifi cation sites: An overview

Md. Mehedi Hasan* and Mst. Shamima Khatun

Background

Post-translational modification (PTM) refers to the covalent and enzymatic modification of proteins during or after protein biosynthesis. In the protein biosynthesis process, the ribosomal mRNA is translated into polypeptide chains, which may further undergo PTM to form the...

Abstract Read Full Article HTML DOI: 10.29328/journal.apb.1001005 Cite this Article