Elaine Teng-Ting LIM | Editor
Affilation: Boston Children’s Hospital, USA
My training was focused on statistical genetics, where I initially developed a novel recessive test
for discovering rare variants in complex diseases (using whole-exome sequencing and
genotyping arrays), and applied the method to uncovering novel variants associated with Type 2
diabetes and autism. In addition, I explored the population genetics of rare and low-frequency
variants in a founder population (Finns), and performed GWAS on quantitative traits obtained
from the Finnish biobanks to discover the association of novel variants with various complex
diseases such as cardiovascular diseases.
I am motivated to understand the genetics of complex and Mendelian disorders in humans, especially for neuro-developmental disorders such as autism, with the purpose of contributing genetic and molecular insights for therapeutics development. I am excited with developing novel techniques and methodologies for discovering and pursuing human genetics in diseases.