Pathology is a scientific clinical knowledge fundamental to modern medical practice and health care. It is a medical specialty that is concerned with the diagnosis of disease based on the laboratory analysis of bodily fluids, such as blood, urine and tissue homogenates or extracts using the knowledge of chemistry, microbiology, hematology and molecular pathology.

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Roger V. Lebo

Roger V. Lebo | Editor-in-Chief

Department of Pathology, Northeast Ohio Medical University, USA,Email:
Tel: (440) 289-7981Department of Pathology, 
Northeast Ohio Medical University, USA
Tel: (440) 289-7981


Francesco Loria

Francesco Loria | Editor-in-Chief

University of Messina, Italy,Tel: 39 0966 22937; Email:

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We publish a wide range of article types in the Clinical, Medical, Biology, Engineering, Chemistry and Pharma.

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Recent Articles

2020-04-24 Research Article

Molecular analysis of immunoglobulins related to salmonella typhi in pediatric patients

Farah Qudsia, Muhammad Rehan and Samreen Riaz*


Typhoid fever is a systemic infection caused by Salmonella enterica serotype typhi. It is of major concern in tropical regions of the world. Highest episodes of typhoid fever occur in Asia i.e.93%. Early diagnosis of the disease is mandatory to lower the mortality rate associ...

Abstract Read Full Article HTML DOI: 10.29328/journal.apcr.1001017 Cite this Article

2020-01-14 Research Article

Uterine precursor lesions in patients with incidental nodal lymphangioleiomyomatosis: A report of 4 cases

Charles M Lombard*


Uterine sections from 6 patients with incidental nodal lymphangioleiomyomatosis (LAM) were examined for LAM lesions by screening these sections with cathepsin K immunohistochemistry (IHC) stains. The hysterectomy specimens were all concurrent with the lymph node dissections i...

Abstract Read Full Article HTML DOI: 10.29328/journal.apcr.1001016 Cite this Article

2019-12-24 Research Article

Pregnancy and childbirth in women aged 40 and over at befelatanana maternity, Madagascar

Rakotomalala Nivoarimelina Zoly*, Rakotozanany Besaina, Razafindraibe Andriatompoina Felanarivo, Ramarokoto Malalafinaritra Patrick Marco, Rafamatanantsoa Jean Florent, Kapche Wato Edith and Randriambololona Domoina Malala Aurelia


Objective: Pregnancy after age 40 remains a concern as it exposes to particular obstetrical complications. Our study aims to determine the risks of complications related to pregnancy and childbirth of women aged 40 and over.

Study design:

Abstract Read Full Article HTML DOI: 10.29328/journal.apcr.1001015 Cite this Article

2019-12-03 Letter to the Editor

Effect evaluation of vitamin D level amongst patients with chronic hepatitis B

Freshteh Osmani*


Vitamin D has immunomodulatory and antifibrotic properties, and therefore used for treatment of many of chronic liver disease [1]. Although there are many reports on the relationship between serum 25-hydroxyvitamin D3 levels and chronic liver diseases, but the relationship betwee...

Abstract Read Full Article HTML DOI: 10.29328/journal.apcr.1001014 Cite this Article

2019-07-23 Research Article

Longitudinal and transverse dimensions of Hypertrophied Cardiomyocytes in human Left Ventricle (LV) at autopsy; Heart failure might result from changes in chamber geometry without contractile weakening

Richard E Tracy*


The shapes and sizes of human cardiomyocytes are accessible to systematic observation under most circumstances only at autopsy. This constraint has seriously curbed the study of these topics, thereby leaving a crippling gap in our understanding of heart failure. In recent yea...

Abstract Read Full Article HTML DOI: 10.29328/journal.apcr.1001013 Cite this Article

2019-03-18 Case Report

Rosai-Dorfman disease presenting as a breast mass

Ding Dai*#, Qi Cai#, Nasreen A. Vohra, Jan Wong, Zsuzsanna P. Therien, Karlene Hewan-Lowe and Ann Sutton


Rosai-Dorfman disease (RDD) is an idiopathic, benign proliferation of histiocytes that can be present in multiple organs such as lymph node, skin, soft tissue, orbit, central nerve system and bone; however, it rarely occurs in the breast. In general, RDD is a painless, firm a...

Abstract Read Full Article HTML DOI: 10.29328/journal.apcr.1001012 Cite this Article

2019-01-29 Case Report

Prostatic inflammatory myofibroblastic tumor: 2-case report with literature review

Ding Dai*, Qi Cai and Ann Sutton


Inflammatory myofibroblastic tumor is rarely seen in the prostate. Most of prostatic tumors are benign. However, local aggressively invading the adjacent organs and recurrence are frequent. Rarely, the malignant transformation and metastasis occurs, especially in elderly pati...

Abstract Read Full Article HTML DOI: 10.29328/journal.apcr.1001011 Cite this Article

2018-12-14 Research Article

Receptor pharmacology and other relevant factors in lower urinary tract pathology under a functional and toxicological approach: Instrument to better manage antimicrobials therapy

Mauro Luisetto*, Naseer Almukhtar, Behzad Nili-Ahmadabadi, Ghulam Rasool Mashori, Kausar Rehman Khan, Ram Kumar Sahu, Farhan Ahmad Khan, Gamal Abdul Hamid and Luca Cabianca


In various patients conditions involved in lower urinary tract disease LUT (like overactive bladder, bladder neck sclerosis, dis –synergy (with our synenrgic contraction between bladder detrusor and bladder neck, BPH, recurrent cysytitis, interstitial cystitis, chronic ...

Abstract Read Full Article HTML DOI: 10.29328/journal.apcr.1001010 Cite this Article

2018-10-05 Research Article

Amyotropyc Lateral Sclerosis and Endogenous -Esogenous Toxicological Movens: New model to verify other Pharmacological Strategies

Mauro Luisetto*, Behzad Nili-Ahmadabadi, Nilesh M Meghani, Ghulam Rasool Mashori, Ram Kumar Sahu, Kausar Rehman Khan, Ahmed Yesvi Rafa, Luca Cabianca, Gamal Abdul Hamid and Farhan Ahmad Khan


In 1874 J.M. Charcot was the first to describe ALS amyotrophic lateral sclerosis, a disease with an high non response therapy rate also to the actual therapy.

ALS is not clearly associate to only single etio-patogenetic movens but many process seem involved.


Abstract Read Full Article HTML DOI: 10.29328/journal.apcr.1001009 Cite this Article

2018-08-28 Research Article

Histological clonal change - A feature for dysplasia diagnosis

Lewei Zhang*, Tarinee Lubpairee, Denise M Laronde, Martial Guillaud, Calum E MacAulay and Miriam P Rosin


Aims: Histological diagnostic criteria are used for the assessment of the degree of dysplasia and hence the risk of cancer progression for premalignant lesions. Clonal changes in the form of hyperorthokeratosis and hyperchromasia that are sharply demarcated f...

Abstract Read Full Article HTML DOI: 10.29328/journal.apcr.1001008 Cite this Article