Alexander E Berezin*
Previous clinical, observation and epidemiologic studies have demonstrated strong association between serum uric acid (SUA) and cardiovascular disease (hypertension, heart failure, and asymptomatic
atherosclerosis), metabolic states (abdominal obesity, diabetes mellitus, metabolic syndrome, insulin resistance) and kidney disease.
Rabindra Nath Das*
Hypertension and blood pressure are closely related, and hypertension is directly related with stroke. There are different type of blood pressures such as basal, diastolic, maximum, mean arterial, systolic, mean central
venous. The present report examines the determinants of systolic blood pressure for two different groups of cardiac patients. One group of cardiac patients is those who underwent dobutamine stress echocardiography, and the other group is Worcester heart attack study. Many systolic blood pressure determinants, their effects, and correlations have been focused in the current report.
Roberto Carlos Burini*, Hugo Tadashi Kano, Mariana Santoro Nakagaki, Caroline das Neves Mendes Nunes and Franz Homero Paganini Burini
High blood pressure (HBP) is a strong, independent and etiologically relevant risk factor for cardiovascular and therefore, the leading cause of preventable deaths worldwide. Hypertension has high medical and social costs. Due to its many associated complications, the use of medical services create high costs with medications which represent almost half of the estimated direct expenses.
Leandro Bueno Bergantin* and Afonso Caricati-Neto
Several experimental studies performed since 1975, using smooth muscles richly innervated by sympathetic nerves to exclude the autonomic infl uence of adjusting refl ex (rodent vas deferens), showed that L-type voltageactivated Ca2+ channels (VACC) blockers completely inhibited neurogenic contractions induced by electrical fi eld
stimulation (EFS) in high concentrations (>10-6 M), but paradoxically increased these EFS-contractions in low concentrations (<10-6 M), suggesting that other mechanisms than only autonomic adjusting refl ex are involved in these paradoxical effects.
Mario Lombardi, Paolo Severi, Andrea Mazza, Maria Grazia Bendini, Elisa Caldarone, Massimo Armeni, Stefania DEmidio and Massimo Leggio*
Hypertension is a complex disorder involving multiple organ systems and the primarily modifiable risk factor for heart disease, which is the leading cause of death among both men and women in the World. Although both men and women develop hypertension, distinct gender differences in the incidence and severity of hypertension are well established where men have a higher incidence of hypertension compared with women of the same age until the sixth decade of life [1,2].