Research Article

Synthesis of some new Schiff bases of Pharmaceutical Interest

Ajay Kumar, Shweta Verma, Arun K Mishra and Sushil Kumar*

Published: 09/26/2017 | Volume 1 - Issue 1 | Pages: 053-056


A series of Schiff bases of diphenylamine derivatives have been synthesized and evaluated in vitro for their antibacterial activity against pathogenic both Gram-positive bacteria B. subtilis and Gram-negative bacteria E. coli using ciprofloxacin as standard drug at conc. of 50 µg/ml and 100 µg/ml. The structures of these compounds were established on the basis of IR and 1H-NMR spectral analysis. The compound (3d) displayed potent antibacterial activity against Bacillus subtilis (17 and 15mm) and Escherichia coli (19 and 17mm) by disc diffusion method.

Read Full Article HTML DOI: 10.29328/journal.aac.1001006 Cite this Article


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