Research Article
Ethical Dimensions of Population Genetic Research in the Caucasus
Ramaz Shengelia* and Theodore G Schurr
Published: 01/20/2017 | Volume 1 - Issue 1 | Pages: 009-015
ABSTRACT
The emergence and establishment of anthropological genetics as an interdisciplinary science is primarily, associated with the development of new genomic technologies. Precision genetic testing on the one hand, and the rapidly increasing number of genetic investigations on the other, have created a set of bioethical dilemmas for genetic and epidemiology research. Such research deals with persons who have the right to the protection of their personal information and confidentiality, and also concerns collective (village, region, ethnic group, state) consciousness, ethnic identity, and traditional culture, i.e., so called “ethnic pride”. In this regard, taking into consideration the results of ongoing field research, we make some recommendations for better management of relationships with individuals and communities and the preparation of questionnaires and informed consent forms that will facilitate similar research projects, especially in such an ethnically, linguistically and culturally diverse region such as the Caucasus.
Read Full Article HTML DOI: 10.29328/journal.hjbm.1001002 Cite this Article
REFERENCES
- Tbilisi. Georgian Soviet Encyclopaedia (GSE). Vol. V; VIII. 1975-1987.
- Народы Мира. Народы Кавказа т. World Nations. Caucasian Nations. Vol. II. pp. 37. 1962.
- Javakhishvili I. Tbilisi. Txzulebani. Works.Vol. I. Tbilisi. 1982.
- Didebulidze, Z.M. Культурная Взаимосвязь народов Грузии и Центрального Кавкааз в 10 -12 веках [Cultural Interconnections of the Peoples of Georgia and Central Caucasus in the 10th- 12th Centuries]. Tbilisi. 1983.
- Ithonishvili V, Caucasus and Caucasians (Historical and Ethnographical Manual), Tb, pp. 30-34; 47-48. 2007.
- Ethnicities in Georgia, Tb. pp. 129-132. 2008.
- Materials for the Ethnography of Georgia. (MEG), Vol’s. 1-24. 1939-90. Tbilisi. masalebisaqarTveloseTnografiisTvis (mse)t. 1-24 1939-1990.
- Qartlis Cxovreba, Vol. I, Tb, pp. 126. 1955.
- Latyshev VV. Data of the Ancient Writers about Scythia and Caucasus, v. СПБ. pp. 239. 1890
- Tbilisi. Issues on History of Georgia (IHG). saqarTvelos istoriis narkvevebi (sin), Vol. II-III-VII. 1977-1982.
- Chahin, M. The Kingdom of Armenia. Reprint: Dorset Press, New York. 1987
- Бурнашев С. Д. Описание горских народов, Курск. 1794.
- Barbujani G, Nasidze I, Whitehead GN. Genetic Diversity in the Caucasus. Human Biology. 1994; 66: 639-668. Ref.: https://goo.gl/8pLhoc
- Nasidze I, Salamatina NM. Genetic characteristics of the Georgian population. Gene Geography. 1996; 10: 105-112.Ref.: https://goo.gl/wqhgeD
- Bulayeva KB, Jorde LB, Ostler C, Watkins S. Genetics and population history of Caucasus populations. Human Biology. 2003; 75: 837-853. Ref.: https://goo.gl/fyU4JL
- Rootsi S, Myres NM, Lin AA, Järve M, King RJ, et al. Distinguishing the co-Ancestries of Haplogroup G Y-chromosomes in the Populations of Europe and the Caucasus. European Journal of Human Genetics. 2012; 20: 1275-1282. Ref.: https://goo.gl/F9J1sz
- Balanovsky O, Dibirova K, Dybo A, Mudrak O, Frolova S. et al. Parallel Evolution of Genes and Languages in the Caucasus region. Molecular Biological Evolution. 2011; 28: 2905-2920. Ref.: https://goo.gl/kv4nOH
- Yunusbaev B, Metspalu M, Järve M, Kutuev I, Rootsi S, et al. The Caucasus as an asymmetric semipermeable barrier to ancient human migrations. Molecular Biology and Evolution. 2012; 29 : 359-365.Ref.: https://goo.gl/QxhfZI
- Comas D, Francesc Calafell, Eva Mateu, Anna Pérez-Lezaun, Elena Bosch, et al. “Trading genes along the Silk Road: mtDNA sequences and the origins of Central Asian populations. American Journal of Human Genetics. 1998; 63:1824-1838. Ref.: https://goo.gl/Wt6LZg
- Di Benedetto G, Ergüven A, Stenico M, Castrì L, Bertorelle G, et al. “DNA Diversity and Population Admixture in Anatolia”. Am J Phys Anthropol. 2001; 115: 144-156. Ref.: https://goo.gl/sPQWsO
- Nasidze I, Ling EY, Quinque D, Dupanloup I, Cordaux R, et al. Mitochondrial DNA and Y-chromosome Variation in the Caucasus. Annals of Human Genetics. 2004; 68:205-221. Ref.: https://goo.gl/EjXBVz
- Perez-Lezaun R, Calafell F, Comas D, Mateu E, Bosch E, et al. Sex-Specific Migration Patterns in Central Asian Populations, Revealed by the Analysis of Y-Chromosome Short Tandem Repeats and mtDNA. American Journal of Human Genetics. 1999; 65: 208-219. Ref.: https://goo.gl/3a5RZU
- Adler DS, Bar‐Oz G, Belfer‐Cohen A, Bar‐Yosef O. Ahead of the game: Middle and Upper Palaeolithic Hunting Behaviors in the Southern Caucasus. Current Anthropology. 2006; 47: 89-118. Ref.: https://goo.gl/Pwi4H5
- Bruch AA. Temporal Corridors of Migration in the Southern Caucasus During the Late Early Pleistocene. Quaternary International. 2012; 279-280: 72-73.
- Algaze G. The Uruk Expansion: The Dynamics of Expansion of Early Mesopotamian Civilization. Chicago: University of Chicago Press. 1993.
- Schurr TG, YardumianA, Shengelia R, Bitadze L, Chitanava D, et al. GeneticDiversity and PopulationHistory in Svaneti, Northwestern Georgia. “CaucasianCivilization: Interdisciplinaryresearch”, Mestia-Tbilisi, Georgia. 2015.
- Beauchamp TL, Childress J. Principles of Biomedical Ethics: New York: Oxford University Press. 2006.
- Mamulashvili B. Bioethics in Cultural Values. Tbilisi.mamulaSvili b. bioeTikakulturulRirebulebebSi. Tbilisi. 2006.
- Javashvili G, Kiknadze G, Barkalaia A. GeorgianLegislation on Human rights in the Sphere of Biomedicine, Tbilisi. 2001.
- Shengelia R. Sanikidze E. Biomedical Ethics. Tbilisi. 2011.
- Sengelia R, sanikiZe E, Tbilisi. Ethical Problems of Clinical Practice and Biomedical Research. klinikuri praqtikisa da biosamedicino kvlevebis eTikuri problemebi. 2013.
- Klyosov AA, Penzev KA. The Aryan Peoples in the Vastness of Eurasia. 2015.
- L.Melikishvili. Ethnical Aspects of Social Security in Multiethnical Society. 2011; 46, 47, 58.