Research Article

Frequent, Genetic Polyps-Familial Adenomatous Polyposis

Anubha Bajaj*

Published: 05/13/2020 | Volume 4 - Issue 1 | Pages: 015-019

Familial adenomatous polyposis is an autosomal dominant syndrome of variable penetration and constitutes the second frequent inherited syndrome enunciating the emergence of a colorectal carcinoma.

Read Full Article HTML DOI: 10.29328/journal.acgh.1001017 Cite this Article


  1. Kanth P, Grimmett J, Champine M, Burt R, Samadder NJ. Hereditary Colorectal Polyposis and Cancer Syndromes: A Primer on Diagnosis and Management. Am J Gastroenterol. 2017; 112:1509-1525. PubMed:
  2. Chintalacheruvu LM, Shaw T, Buddam A, Diab O, Kassim T, et al.  Major hereditary gastrointestinal cancer syndromes: A narrative review. J Gastrointestinal Liver Dis. 2017; 26: 157-163. PubMed:
  3. Carr S, Kasi A. Familial adenomatous polyposis. StatPearls Publishing 2020. PubMed:
  4. Sammour T, Hayes IP, Hill AG, Macrae FA, Winter DC. Familial colorectal cancer syndrome: an overview of clinical management. Expert Rev Gastroenterol Hepatol. 2015; 9: 757-764. PubMed:
  5. DE Marchis ML, Tonelli F, Quaresmini D, Lovero D, Della-Morte D, et al. Desmoid tumours in familial adenomatous polyposis. Anticancer Res. 2017; 37: 3357-3366. PubMed:
  6. Syngal S, Brand RE, Church JM, Giardiello FM, Hampel HL, et al. American College of Gastroenterology ACG: clinical guidelines: genetic testing and management of hereditary gastrointestinal cancer syndromes. Am J Gastroenterol. 2015; 110: 223-262. PubMed:
  7. Chittleborough TJ, Warrier SK, Heriot AG, Kalady M, Church J. Dispelling misconceptions in the management of familial adenomatous polyposis. ANZ J Surg. 2017; 87: 441-445. PubMed:
  8. Waller A, Findeis S, Lee MJ. Familial adenomatous polyposis. J Paediatr Genet. 2016; 5: 78-83. PubMed:
  9. Dinarvand P, Davaro EP, Doan JV, Ising ME, Evans NR, et al. Familial adenomatous polyposis syndrome: an update and review of extra-intestinal manifestations. Arch Pathol Lab Med. 2019; 143: 1382-1398. PubMed: