Research Article

Mitomycin-C Use and Complications in Ophthalmology

Tongabay Cumurcu*

Published: 06/28/2017 | Volume 1 - Issue 1 | Pages: 029-032


Mitomycin-C, First found its way into ophthalmic use in 1969, in Japan, where recurrent pterygia were successfully treated with the drug which is an antineoplastic / antibiotic agent isolated from the soil bacterium Streptomyces caespitosus [1]. It is an anti-metabolite with anti-proliferative effect on cells showing the highest rate of mitosis by inhibiting DNA synthesis and interferes with RNA transcription and protein synthesis [2].

Read Full Article HTML DOI: 10.29328/journal.hceo.1001004 Cite this Article


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