Clinical endocrinology is the study of the endocrine system, its function and its diseases or abnormalities. The endocrine system refers to those organs in the body which release hormones that regulate many of the body’s functions such as the pancreas, the pituitary gland and the thyroid gland. Clinical endocri... Readmore

Aim of the Journal

The manuscripts published in Annals of Clinical Endocrinology and Metabolism aims to augment the understanding in basic physiological mechanisms as well as creating new therapeutic approaches towards endocrine and metabolic research.

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Recent Articles

Case Report

Endocrine abnormalities in two siblings with Rothmund Thomson Syndrome

Rothmund-Thomson syndrome is a rare autosomal recessive disorder characterized by poikiloderma (skin atrophy, telangiectasia, hyper- and hypopigmentation), congenital skeletal abnormalities, short stature, premature aging, and increased risk of malignant disease.

Read Full Article HTML DOI: 10.29328/journal.acem.1001010 Citation

Research Article

Comparison of Efficacy and Safety of Hydroxychloroquine and Teneligliptin in Type 2 Diabetes Patients who are Inadequately Controlled with Glimepiride, Metformin and Insulin therapy: A Randomized Controlled Trial with Parallel Group Design

Aim: The aim of the present study is to assess the efficacy and safety of Hydroxychloroquine in comparison with Teneligliptin in type 2 diabetes patients whose blood glucose levels were inadequately controlled with metformin, Glimepiride and insulin therapy.

Read Full Article HTML DOI: 10.29328/journal.acem.1001009 Citation

Case Report

A Pancreatic Neuroendocrine Tumor with an Unusual Flush

A 60-year-old man presented with an unusual history of lower limb flushing. A CT scan suggested a pancreatic neuroendocrine tumor. After a robotic distal pancreatectomy, his symptoms completely resolved. The tumor was positive for synaptophysin and chromogranin. This case emphasizes the import...

Read Full Article HTML DOI: 10.29328/journal.acem.1001008 Citation

Research Article

Exercise preserves pancreatic β-cell mass and function in obese OLETF rats

Although exercise has been proposed to be benefi cial to type 2 diabetes, its effects on β-cell function and mass remain unclear. In the present study, the effects of long-term swimming training on the function and mass of β-cells in diabetic OLETF rats were examined.

Read Full Article HTML DOI: 10.29328/journal.acem.1001007 Citation

Review Article

New pharmacological strategies in some metabolic endocrine disorder under a toxicological approach

In this review After Observing biomedical literature (starting from some heart disease) results that some pathological phenomena are deeply involved in some metabolic endocrine condition:

Read Full Article HTML DOI: 10.29328/journal.acem.1001006 Citation Views: 2503


Indian spices and Caffeine treatment for Obesity and Cardiovascular disease

The global obesity epidemic that was previously reported [1,2] is now to worsen with obesity to double in 73 countries around the world [3,4]. Improving the health of obese individuals by dietary restriction, anti-obese foods and increased physical activity [1] has not reduced the global obesi...

Read Full Article HTML DOI: 10.29328/journal.acem.1001005 Citation Views: 3208

Research Article

Diabetes and red blood parameters

Type 2 diabetes is a common disease in these days and day by day it is arising. The main focus of the study was to investigate association of packed cell volume (PCV), Mean Corpuscular Volume (MPV), Mean
Corpuscular Hemoglobin Concentration (MCHC),

Read Full Article HTML DOI: 10.29328/journal.acem.1001004 Citation Views: 3472

Research Article

Parathyroid Functions in Thalassemia Major Patients

Background: Hypoparathyroidism is well known to occur in thalassemia major patients, but it is thought to be uncommon and its incidence is considered to be decreasing with improvements in chelation therapy. The
objective of this study was to assess the prevalence of parathyroid dysfunc...

Read Full Article HTML DOI: 10.29328/journal.hcem.1001003 Citation Views: 5630

Research Article

Effect on Vitamin D status of Breastfeeding Infants after Vitamin D3 Supplementation during Breastfeeding Lactation: A double-blind randomized controlled trial

Background: Vitamin D deficiency in pregnancy increases several risks of breastfed mothers. To prevent these adverse events, vitamin D supplementation during pregnancy and lactation is recommended, but suggested dose ranges vary.

Read Full Article HTML DOI: 10.29328/journal.hcem.1001002 Citation Views: 5624

Case Report

Recurrent Cardiac Events Driven by Prothrombotic Burden in a Patient Undergoing Lipoprotein Apheresis for High Lp(a) Levels

Introduction: Lipoprotein (a) [Lp(a)] is a marker for cardiovascular disease, involved in pathogenesis and progression of atherosclerosis. In selected high-risk patients, lipoprotein-apheresis could optimize secondary prevention and improve prognosis.

Read Full Article HTML DOI: 10.29328/journal.hcem.1001001 Citation Views: 3929