Rene Javier Hernandez Bautista

Rene Javier Hernandez Bautista | Editor

Affilation: Universidad de Santiago de Compostela, Spain

I'll finish soonmy postdoctoral fellow (two years) in the Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), under supervision of Dr. Rubén Nogueiras Pozo and Prof. Carlos Diéguez from University of Santiago de Compostela, Spain. So I´m looking for another place to continue my preparation. I have an academic background in biological sciences combined with a strong practical work experience in basic research, especially in obesity and metabolic disorders fields. I studied Bio-pharmaceutical Chemistry in “Benemérita Universidad Autónoma de Puebla” (BUAP-Mexico) and a specialty of Clinical Biochemistry. After completed my degree in 2005, I enrolled in the Clinical Chemistry Research group leading by Prof. Eduardo Miguel Brambila Colombres (BUAP-Mexico) where I focus in the study of inflammatory profile after surgery process and their relationship with acute phase proteins, specifically with Metallothioneins. After two years in this laboratory I obtained the Master Degree (year 2007) necessary step to continue with the thesis project, however at that time I got a grant from the “Consejo Nacional de Ciencia y Tecnología” (abbreviated CONACYT). I defended my PhD thesis entitle “Attenuation of metabolic, inflammatory and oxidative stress parameters throughout the life of MSG obese mice (male and female)” on February 20th 2015 under the supervision of Prof. Mina Konigsberg, Dr. Norma Edith Lopéz Díaz Guerrero, and Dr. Francisco Javier Alarcón Aguilar (Bioenergetics and Cellular Again Laboratory and Pharmacology Laboratory, Health Sciences Department, Universidad Autónoma Metropolitana, Mexico D.F, Mexico). This work presents a suitable model for studying obesity behavior and their relations with other disorders associated like diabetes and insulin resistance, that leads to several publications (Lopez DG, NE., et al. 2013. Gaceta Médica de México. Vol. 149: 438-47; Merino-Aguilar, H., et al. 2014. Nutrients. 29;6(2):591-604; Hernández-Bautista R. J., et al. 2014. Int J Mol Sci. 15(7):11473-94).Independently during my PhD, I had carried out other experimental research lines like the study of damage oxidative by obesity as Low-grade inflammatory process in aging. During the PhD period, I handle several physiological and molecular techniques includingwestern blot, RT-PCR, ELISA, electrochemical and enzymatic technics for study of oxidative damage. After that in July 2015, I moved to the laboratory of Prof. Rubén Nogueiras Pozo in Santiago de Compostela (Spain) for a period of two years (currently until June 2017) where I do a training in different techniques related to energy metabolism and that fall into some publications also (Eva Tudurí., et al. J. Mol. Endocrinol.  Submitted, 2016.; O Al-Massadi*., et al. Cell Rep. Submitted. 2016.; M Quiñones*., 2017. In preparation.) Specifically, I acquire a deep training in animal models manipulation, metabolic phenotyping, knock down or overexpress of several proteins or factors in hypothalamus by Stereotaxic Surgery (virogenetics), measurement of respiratory quotient, energy expenditure or locomotor activity by indirect calorimetric system, measurement of brown adipose tissue temperature in vivo by thermography, study of the glucose homeostasis and insulin sensitivity by GTT or ITT) together with extensive use of molecular techniques for the study of different proteins in relevant metabolic tissues such as white adipose tissue, brown adipose tissue, liver or specific hypothalamic nucleus (western blot or RT-PCR).

I am a person that I consider myself with the following capacities indispensable for the science carrier: enthusiastic, energetic, autonomous and with own initiative. Highly motivated, creative and imaginative, inspired and innovative. With established goals and hardworking, being persistent and constant. I like to work as a team and I think I have the potential to lead a team work. I also consider myself a rigorous, responsible and valued person (ethical behavior). I am also a resolute person, capable of taking decisions and taking risks. Within my personal skills it is worth noting: I am able to use technology efficiently. I have the ability to learn new concepts and analytical sense and with a high development potential. I believe that I possess the technical knowledge applicable to the sector and the products of the company or institution where I am required. For my future career, I see aEditorial Board Member as the ideal way to broaden my knowledge and scientific activity. The quality and interest of the data published are really amazing, and projects have a direct relationship with my scientific background, so I completely sure that your research is the best option for me. In addition toscientific knowledge,thepostdoc will allow me to continue growing as a person.

Research Interest

Hypothalamic study of intracellular pathways of involved peptides on food intake. Metabolic characterization and phenotyping of KO mice. Metabolic study and target search involved in obesity (Sirt3 and p53). Study of low-grade inflammatory and their impact on energy balance.