DNA Damage and Repair in Simulated Spaceflight-induced Bone loss; Solicitation: NASA Post-Doctoral Program (NPP); Awarded in May 2013 and started October 2013. Skeletal Responses to a Simulated ISS Environment; Solicitation: NNJ13ZSA002N-FLAGSHIP; Role Co-I; Awarded in May 2014. Free Radical Theory of Aging in Space; Solicitation: NNH14ZTT001N; role Co-I; Selected in August 2014
Responses of Cardiac Tissue to Simulated Weightlessness; Solicitation: NNJ14ZSA001N-FLAGSHIP; role co-I, Awarded in January 2016
Candidate nutritional countermeasure to mitigate adverse effects of spaceflight; Solicitation: NNJ15ZSA001N-OMNIBUS; role PI, selected in April 2016.
Andrea Piccin, Unit Bolzano Regional Hospital, Italy
"Dr Andrea Piccin is a consultant haematologist currently working at the Haematology Department & Bone Marrow Transplantation Unit of San Maurizio Regional Hospital of Bolzano, South Tirol, Italy. He also actively collaborates with the Medical University of Innsbruck in Austria on development of future research projects in Haematology. Over the last years he has been working in the main Units of Haematology in Dublin Hospitals in Ireland. In 2009 Dr Piccin obtained a PhD degree at the University of Trinity College Dublin on a study on “New insight in Sickle Cell Anaemia pathophisiology”. Other activities comprise a study on “Autologus Recovery in Aplastic Anaemia” on behalf of the EBMT Severe Aplastic Anaemia working-party. Previous experience include a MD thesis on “Tandem PBSCT for Multiple Myeloma” (Verona University, Italy) and another MD degree in Paediatric Oncohaematology “Gene Therapy in Medulloblastoma in vivo and in vitro” (Padua University, Italy). He received his Medical Degree in 1996 at Padua University and the Higher Specialist Degree in Haematology in 2002 at Verona University. Dr Piccin has been also awarded by the Italian President Giorgio Napolitano for his contribution in the assistance of patients with the medal of “Solidarity” and the honour of Sir “Cavaliere”. "
Xingbin Hu, Xijing Hospital, China
ZhongCheng Gong, Xinjiang Medical University, China
Momcilo Pavlovic, College of Vocational Studies, Serbia
Laila El fenniri, Hygiene and Public Health Engineer, Morocco
Shyam Ajay Patel, Internal Medicine Residency and Clinical Investigator Pathway, Stanford University Medical Center, Stanford, CA, USA
Biography: I attended Rutgers – New Jersey Medical School from 2006-2013 where I completed the physician-scientist training program (PSTP) program. The disciplines in which I trained were stem cell and cancer biology. My thesis focused on the mechanisms of breast cancer dormancy in the bone marrow. In brief, we found that bone marrow mesenchymal stem cells (MSCs) can favor immune subversion of breast cancer cells by inhibiting various anti-tumor responses (Patel SA et al., J. Immunol. 2010; 184:5885-5894). Mechanistically, we found that MSCs induce Tregs and thus dampen immune effector responses against cancer. We also found that a subset of breast cancer cells, characterized by the expression of the pluripotency marker Oct4, is responsible for initiating tumors (Patel SA et al., Sci. Rep. 2012; 2:906). Finally, we showed the MSCs preferentially protect the cancer stem cell population in the bone marrow (Patel SA et al., J. Cancer Stem Cell Res. 2014; 2: e1003).
Research Interest: tumor microenvironment, tumor immunology, translational cancer medicine, breast cancer biology, acute myeloid leukemia, and genomics.