Introduction

Bone marrow is the soft spongy tissue that lies within the hollow interior of long bones. In adults, marrow in large bones produces new blood cells. Bone marrow forms around 4% of total body weight. There are two types of bone marrow: red marrow that is responsible fo... Readmore

Aim of the Journal

International Journal of Bone Marrow Research aims to publish valuable researches encompassing all aspects of bone marrow research that can assist in making bone marrow, stem cell or cord blood transplant an overwhelming experience for the patients and the doctors.

The manuscripts published in International Journal of Bone Marrow Research also seek to focus on the vital role of bone marrow in understanding blood and autoimmune diseases and in evaluating treatment options for patients.

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There is a precept- "two heads result in more fruitful thing than one head alone". Heighten Science Publication unique concept of membership is based on this precept. Readmore

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Heighten Science Publication Corporation uses Double-Blind Peer Review policy for all the journals. Under this policy both the reviewers and authors identities are concealed... Readmore

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Articles

We publish a wide range of article types in the Clinical, Medical, Biology, Engineering, Chemistry and Pharma.

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Recent Articles

2019-11-05 Review Article

Drug abuse and its ramifications on skeletal system

Das Sanjita* and Kumar Naveen

The purpose of this study is to highlight the drug abuse hazards and preventive aspects. From a public health perspective, substance abuse has long been a source of major concern, both for the individual’s health and for wider society as a whole. The UK has the highest rates of recorded ...

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2019-08-16 Letter to the Editor

Serum MicroRNA-155 in Acute Graft-Versus-Host-Disease (aGVHD)

Yvonne A Efebera*, Amy S Ruppert, Apollinaire Ngankeu, Sabrina Garman, Prasanthi Kumchala, Alan Howard, Steven M Devine, Parvathi Ranganathan and Ramiro Garzon

Allogeneic hematopoietic stem cell transplant (alloHSCT) is a curative treatment for many hematologic malignancies. Unfortunately, about  30-50% of all recipients undergoing alloHSCT develop acute graft-versus-host-disease (aGVHD), which is associated with high morbidity and mortality [1,...

Read Full Article HTML DOI: 10.29328/journal.ijbmr.1001007 Citation

2019-06-21 Research Article

Bone marrow histology in CALR mutated thrombocythemia and myelofi brosis: results from two cross sectional studies in 70 newly diagnosed JAK2/MPL wild type thrombocythemia patients

Jan Jacques Michiels, Yonggoo Kim, Myungshin Kim, Francisca Valster, Vincent Potters, Zwi Berneman, Alain Gadisseur, Wilfried Schroyens and Hendrik De Raeve

The clinical phenotypes in 268 JAK2V617F mutated MPN patients in the Seoul study were PV in 101, ET in 95 and MF in 78 and 56 CALR mutated MPN consisted of PV in none, ET in 40 and MF in 16 cases. CALR mutated MPN patients were younger than JAK2V617F mutated MPN patients (mean ages 57.5 and 66...

Read Full Article HTML DOI: 10.29328/journal.ijbmr.1001006 Citation

2019-05-13 Case Report

The forgotten player in the surgical history

Yves Cirotteau*

The research concerning a preventive treatment of an osteoporitic femoral neck fracture started in 1990 because the surgical procedure of unstable femoral neck fractures is difficult. After effects are frequent and their number will increase in the next decade. The goal is to reinforce the fem...

Read Full Article HTML DOI: 10.29328/journal.ijbmr.1001005 Citation

2019-04-17 Research Article

The PVSG/WHO versus the Rotterdam European clinical, molecular and pathological diagnostic criteria for the classification of myeloproliferative disorders and myeloproliferative neoplasms (MPD/MPN): From Dameshek to Georgii, Vainchenker and Michiels 1950-2018

Jan Jacques Michiels* and Hendrik De Raeve

The present article extends the PVSG-WHO criteria into a simplified set of Rotterdam and European Clinical, Molecular and Pathological (RCP/ECMP) criteria to diagnose and classify the myeloproliferative neoplasms (MPNs). The crude WHO criteria still miss the masked and early stages of ET and P...

Read Full Article HTML DOI: 10.29328/journal.ijbmr.1001004 Citation

2019-04-15 Research Article

Primary myelofibrosis is not primary anymore since the discovery of MPL515 and CALR mutations as driver causes of mono-linear megakaryocytic and dual megakaryocytic granulocytic myeloproliferation and secondary myelofibrosis

Jan Jacques Michiels* and Hendrik De Raeve

Primary myelofibrosis (PMF) is a distinct clinicopathological myeloproliferatve disease (MPD) not preceded by any other MPD ET, PV, CML,... Combined use of bone marrow histology and increased erythrocyte counts above 5.8x1012/L can replace increased red cell mass at time of presentation as the...

Read Full Article HTML DOI: 10.29328/journal.ijbmr.1001003 Citation

2019-03-01 Research Article

European Clinical Laboratory, Molecular and Pathological (ECMP) criteria for prefibrotic JAK2V617F-Thrombocythemia and Polycythemia Vera versus MPL515- and CALR-Thrombocythemia and Myelofibrosis: From Dameshek to Michiels 1950-2018

Jan Jacques Michiels*, Zwi Berneman, Wilfried Schroyens, Fibo W J ten Kate, King Lam and Hendrik De Raeve

The broad spectrum of heterozygous versus homozygous JAK2V617F mutated MPN consists ET, ET with early features of PV (prodromal PV), classical PV, masked PV, advanced PV and post-PV myelofibrosis. Combined use of bone marrow histology and increased erythrocyte counts above 5.8x1012/L can repla...

Read Full Article HTML DOI: 10.29328/journal.ijbmr.1001002 Citation

2017-07-11 Research Article

Pure Erythroid Leukemia: The Sole Acute Erythroid Leukemia

Fauzia Shafi Khan*, Khalid Mahmood and Alia Ahmad

Pure Erythroid Leukemia (PEL) is an aggressive and exceedingly rare form of acute leukemia. In the 2008 WHO classification PEL was one of the subtypes of acute erythroid leukemia the other subtype being erythroleukemia (erythroid/ myeloid). In the 2016 WHO classification update, erythroleukemi...

Read Full Article HTML DOI: 10.29328/journal.ijbmr.1001001 Citation