Respiratory diseases affect the air passages together with the nasal passages, the bronchi and the lungs. They comprise infections, such as allergies and bronchitis; as well as chronic conditions such as asthma and chronic obstructive respiratory diseases. Allergies are hypersensitive immune responses to substances or allergen that either enter or come in contact with the body. Asthma is a long-term lung condition. People with asthma have subtle airways in their lungs which causes a flare-up making it harder to breathe.
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2021-04-08 Research Article
L Klimek*, J Hagemann, I Casper, T Huppertz, A Bedbrook and J Bousquet
Background: Chronic rhinosinusitis (CRS) is a heterogeneous and multifactorial inflammatory disease of the nasal and paranasal mucosa. To date, no internationally standardized uniform classification has been developed for this disease.
Usually, a phenotype classificati...
2021-03-19 Research Article
Pastorello Elide Anna*, Borgonovo Linda, Piantanida Marta, Schroeder Jan Walter, Pravettoni Valerio, Pastori Stefano, Bilo’ Maria Beatrice, Toniato Andrea, Nichelatti Michele, Preziosi Donatella, Aversano Maria Gloria and Farioli Laura
Introduction: Risk factors for systemic reactions (SRs) from hymenoptera venom (HV) allergy are well known in the adult population but they have been little studied in the pediatric one.
Method: The aim of our study was to identify risk factors for SRs in a populati...
2021-02-26 Short Communication
Cinthya Covessi Thom de Souza, Nelson Augusto Rosario Filho, Ernesto Akio Taketomi, Juliana Silva Miranda and Ricardo Henrique Moreton Godoi
By researching the factors related to exposure to indoor and outdoor allergens, such seasons, climate changes and particulate matter, allergists can screen the sensitization profile of individuals according to their exposures and conduct preventive treatment and individualized immunotherapy.
2021-02-17 Research Article
Rory Chan, Chris RuiWen Kuo and Brian Lipworth*
Airway hyperresponsiveness (AHR) is a hallmark of persistent asthma measured using direct or indirect airway bronchial challenge testing. The purpose of this study is to investigate the putative relationships between type 2 inflammatory biomarkers, airway geometry (FEV1 and F...
2021-02-05 Research Article
Antonio Madrid* and Nicholas Bennett
Disruptions in Maternal-infant Bonding are shown to be the mediating variable between maternal distress and the subsequent expression of childhood asthma. When the mothers’ bonding is repaired, their children’s asthmatic symptoms diminish or remit. This study eval...
2020-10-20 Case Report
Mohammad Nabavi, Parisa Rezaeifar, Morteza Fallahpour, Saba Arshi, Mohammad Hassan Bemanian, Sima Shokri and Afshin Rezaeifar*
Cystic fibrosis (CF) is a hereditary syndrome composed of exocrine gland dysfunction involving multiple systems which if untreated may result in chronic respiratory infections, pancreatic enzyme deficiency and failure to thrive. The association between CF and othe...
2020-10-06 Research Article
Akihiro Shiroshita*, Yu Tanaka, Kei Nakashima, Atsushi Shiraishi, Hiroki Matsui and Masahiro Aoshima
Introduction: There is currently no strategy for identifying chronic obstructive pulmonary disease (COPD) patients whose pulmonary function could benefit from inhaled corticosteroids. We investigated whether a 28-day regime of inhaled corticosteroids improved pulmonary functi...
2020-08-11 Case Report
Francesco Arcoleo, Carmelo Fabiano, Stefania Leto Barone and Enrico Cillari*
Familial Mediterranean fever (FMF) is an autosomal recessive autoinflammatory disease caused by mutation(s) in the Mediterranean fever (MEFV, pyrinmarenostrin) gene [1,2].
2020-04-30 Research Article
Fadwah M Al-Sharif*
Background: Globally, Alzheimer’s disease (AD) affects millions of elderly individuals are affected with AD who suffer from decline in cognitive ability. However, immune system dysfunction has a role in AD pathogenesis. However, pharmacological therapeu...
Asthma is a chronic respiratory disease characterized by chronic airway inflammation. Common manifestations of asthma include wheezing, chest tightness, cough, shortness of breath. Diagnosis of asthma requires clinical documentation of respiratory symptoms, exacerbation of s...