Respiratory diseases affect the air passages together with the nasal passages, the bronchi and the lungs. They comprise infections, such as allergies and bronchitis; as well as chronic conditions such as asthma and chronic obstructive respiratory diseases. Allergies are hypersensitive immune responses to substances or allergen that either enter or come in contact with the body. Asthma is a long-term lung condition. People with asthma have subtle airways in their lungs which causes a flare-up making it harder to breathe.

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Recent Articles

2021-04-08 Research Article

Immunological background for treatments with biologicals in CRSwNP

L Klimek*, J Hagemann, I Casper, T Huppertz, A Bedbrook and J Bousquet


Background: Chronic rhinosinusitis (CRS) is a heterogeneous and multifactorial inflammatory disease of the nasal and paranasal mucosa. To date, no internationally standardized uniform classification has been developed for this disease.
Usually, a phenotype classificati...

Abstract Read Full Article HTML DOI: 10.29328/journal.aaai.1001026 Cite this Article

2021-03-19 Research Article

Higher venom-specific IgE levels differentiate children with previous local large reactions from children with previous systemic reactions of different severity

Pastorello Elide Anna*, Borgonovo Linda, Piantanida Marta, Schroeder Jan Walter, Pravettoni Valerio, Pastori Stefano, Bilo’ Maria Beatrice, Toniato Andrea, Nichelatti Michele, Preziosi Donatella, Aversano Maria Gloria and Farioli Laura


Introduction: Risk factors for systemic reactions (SRs) from hymenoptera venom (HV) allergy are well known in the adult population but they have been little studied in the pediatric one.

Method: The aim of our study was to identify risk factors for SRs in a populati...

Abstract Read Full Article HTML DOI: 10.29328/journal.aaai.1001025 Cite this Article

2021-02-26 Short Communication

Cyn d 1 airborne allergen in a Southern Brazilian city

Cinthya Covessi Thom de Souza, Nelson Augusto Rosario Filho, Ernesto Akio Taketomi, Juliana Silva Miranda and Ricardo Henrique Moreton Godoi

By researching the factors related to exposure to indoor and outdoor allergens, such seasons, climate changes and particulate matter, allergists can screen the sensitization profile of individuals according to their exposures and conduct preventive treatment and individualized immunotherapy.

Abstract Read Full Article HTML DOI: 10.29328/journal.aaai.1001024 Cite this Article

2021-02-17 Research Article

A retrospective cohort study to evaluate the relationship of airway hyperresponsiveness to type 2 biomarkers in persistent asthma

Rory Chan, Chris RuiWen Kuo and Brian Lipworth*


Airway hyperresponsiveness (AHR) is a hallmark of persistent asthma measured using direct or indirect airway bronchial challenge testing. The purpose of this study is to investigate the putative relationships between type 2 inflammatory biomarkers, airway geometry (FEV1 and F...

Abstract Read Full Article HTML DOI: 10.29328/journal.aaai.1001023 Cite this Article

2021-02-05 Research Article

Helping asthmatic children through bonding therapy

Antonio Madrid* and Nicholas Bennett


Disruptions in Maternal-infant Bonding are shown to be the mediating variable between maternal distress and the subsequent expression of childhood asthma. When the mothers’ bonding is repaired, their children’s asthmatic symptoms diminish or remit. This study eval...

Abstract Read Full Article HTML DOI: 10.29328/journal.aaai.1001026 Cite this Article

2020-10-20 Case Report

Cystic fibrosis and congenital adrenal hyperplasia: A rare occurrence with diagnostic dilemmas, similarities and contradictions

Mohammad Nabavi, Parisa Rezaeifar, Morteza Fallahpour, Saba Arshi, Mohammad Hassan Bemanian, Sima Shokri and Afshin Rezaeifar*


Cystic fibrosis (CF) is a hereditary syndrome composed of exocrine gland dysfunction   involving multiple systems which if untreated may result in chronic respiratory infections, pancreatic enzyme deficiency and failure to thrive. The association between CF and othe...

Abstract Read Full Article HTML DOI: 10.29328/journal.aaai.1001021 Cite this Article

2020-10-06 Research Article

Short-term responses to high-dose inhaled corticosteroid treatment in patients with chronic obstructive pulmonary disease with a fractional nitric oxide concentration over 35 parts per billion: A single-centre pre–post study

Akihiro Shiroshita*, Yu Tanaka, Kei Nakashima, Atsushi Shiraishi, Hiroki Matsui and Masahiro Aoshima


Introduction: There is currently no strategy for identifying chronic obstructive pulmonary disease (COPD) patients whose pulmonary function could benefit from inhaled corticosteroids. We investigated whether a 28-day regime of inhaled corticosteroids improved pulmonary functi...

Abstract Read Full Article HTML DOI: 10.29328/journal.aaai.1001020 Cite this Article

2020-04-30 Research Article

Immune system and quality of life following aerobic exercise versus resistance exercise training among Alzheimer’s

Fadwah M Al-Sharif*


Background: Globally, Alzheimer’s disease (AD) affects millions of elderly individuals are affected with AD who suffer from decline in cognitive ability. However, immune system dysfunction has a role in AD pathogenesis. However, pharmacological therapeu...

Abstract Read Full Article HTML DOI: 10.29328/journal.aaai.1001018 Cite this Article

2020-01-10 Editorial

Retrosternal goiter mimicking asthma: A diagnostic challenge

Yiannakopoulou Eugenia*


Asthma is a chronic respiratory disease characterized by chronic airway inflammation. Common manifestations of asthma include wheezing, chest tightness, cough, shortness of breath. Diagnosis of asthma requires clinical documentation of respiratory symptoms, exacerbation of s...

Abstract Read Full Article HTML DOI: 10.29328/journal.aaai.1001017 Cite this Article