Affilation: University of Zagreb, Croatia (Hrvatska)
Journal Associated: Archives of Clinical and Experimental Orthopaedics
Lovorka Grgurevic, MD, PhD, is a Professor of Anatomy and Clinical Anatomy and Head of Department of Proteomics at the Center for Translational and Clinical Research, University of Zagreb School of Medicine. Her scientific interest includes the structure and function of bone morphogenetic proteins in biological fluids, drug formulation development and toxicology testing, and novel targets for prevention of fibrosis. She has discovered novel BMP1 circulating isoforms in the plasma of animals and patients with various diseases, followed by testing of their mechanism of action, safety and efficacy in animal models of acute and chronic renal, liver and heart injury. She discovered a new carrier for BMPs and tested its efficacy in animal models of bone defects which served as the basis of the project OSTEOGROW. The overall objective of the project OSTEOGROW related with bone regeneration is the development of a safe, effective and affordable new therapeutic solution for the enhancement of bone healing and prevention of bone non-unions in the preclinical and clinical setting. Dr. Grgurevic discovered novel biomarkers for bone repair, breast and prostate cancer prognosis. She received a new laboratory installation grant from the Croatian Science Foundation and was awarded in 2016 by the Croatian Academy of Sciences and Arts for scientific excellence. Inventor on 12 patents protected at American, European, Canadian, Australian and Japanese patent office’s. Member of Croatian Medical Association, European Calcified Tissue Society and Croatian Calcified Tissues Society. She is married and mother of three children.
Research Interest: Bone regeneration; Formulation of novel carriers for BMP molecules; Biomarkers; Proteomic research; Rare bone disease; Antifibrotic program