SARS-CoV-2 Infection, COVID-19, and long covid: Saga of erratic immune response, waning immunity, and immune system failure

Vinod Nikhra*

Abstract

Introduction - evolution of SARS-CoV-2 variants: With the unrestrained pandemic for over last one-and-half year, SARS-CoV-2 seems to have adapted to its habitat, the human host, through mutations that facilitate its replication and transmission. The G variant incorporating D6...

The SARS CoV-2 spike domain, RGD and integrin binding effect-relationship for vaccine design strategy

Luisetto M*, Tarro G, Khaled Edbey, Almukthar N, Cabianca L, Mashori GR, Ahnaf Ilman, Yesvi AR and Latyschev OY

Abstract

Related the need to search new strategy in vaccine design in order to reduce also some rare effect like trombosys for some registered products it is interesting the role played by the SPIKE RGD domain.

The binding with molecules like Fibronectin is a process that mu...

Myxedema coma in COVID-19

Yuichi Takashi* and Daiji Kawanami*

Abstract

SARS-CoV-2 infection is associated with thyroid disorders. It has been reported that myxedema coma (MC) can be complicated with COVID-19. COVID-19-related thyroid disorders consist of a broad spectrum of thyroid dysfunction, from thyrotoxicosis to decompensated hypothyroidism...

COVID-19 Associated acute limb ischemia

Yogendra Mishra*, Satish Kumar and Meghna K

A 78-year-old man, known case of, diabetes mellitus, and hypertension presented with fever, dry cough and dyspnea of five-day duration.

Novel Coronavirus Disease (COVID-19): An extensive study on evolution, global health, drug targets and vaccines

Abdul Ashik Khan, Tanmoy Dutta, Palas Mondal, Manab Mandal, Swapan Kumar Chowdhury, Minhajuddin Ahmed, Nabajyoti Baildya, Sourav Mazumdar and Narendra Nath Ghosh*

Abstract

The Coronavirus disease-2019 (COVID-19), has become a worldwide pandemic and the scientific communities are struggling to find out the ultimate treatment strategies against this lethal virus, Severe Acute Respiratory Syndrome Coronavirus–2 (SARS-CoV-2). Presently, there...

OPEN and CLOSED state of SPIKE SARS-COV-2: relationship with some integrin binding. A biological molecular approach to better understand the coagulant effect

Luisetto M, Khaled Edbey, Mashori GR, Ahnaf Ilman, Yesvi AR and Latyschev OY

Abstract

Related the physio-pathological process of COVID-19 disease it is interesting to focus to the aspect.

Played by interaction of Sars-Cov-2 protein with integrins of human epithelial pulmonary cell.

A bio molecular approach help in to deeply verify the invol...

Impact of COVID-19 outbreak on urology practice in India

Mahendra Singh*, Himanshu Pandey, Prateek Gupta, Gautam Ram Choudhary, Vipin Tyagi, Vijay Kumar Sarma Madduri and Nikita Shrivastava

Abstract

Background: The rapid spread of “Coronavirus Disease 2019’ (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus-type 2 (SARS-CoV-2) significantly impacted health care facilities all across the globe. To assess impact on urology practice in our countr...

Pulmonary Involvement in COVID-19 and ‘Long Covid’: The Morbidity, Complications and Sequelae

Vinod Nikhra*

Abstract

Introduction: the perennial pandemic: There are serious challenges posed by the SARS-CoV-2 virus and COVID-19 as the disease. With the persistence of the pandemic over one and half year, it is being feared that the COVID-19 may have become the new reality associated with huma...

Suicide in teenagers during the COVID-19 pandemic in Cuba: actions for its prevention

Claudia Elvira Casamayor Leiza, Julio César Pérez Yero, Maydell Pérez Inerárity* and Brayan Chávez Miguel

Abstract

Introduction: Suicidal behavior in teenagers constitutes a health problem that, given the necessary measures of social isolation taken by the global emergency of the COVID-19 pandemic, must generate timely actions for its prevention and control from the public health services...

Precision and personalized vaccines needed to face COVID-19 pandemic

Dahmani Fathallah M*

Among the abounding lessons we learned from the SARS-C0V-2 pandemic is the uttermost determinant that people are not equal before the severity of COVID-19. Indeed, the disease course differs with age, gender, ethnicity, underlying clinical conditions and virus variants. O...

Total aortic occlusion associated with SARS-CoV-2 (COVID-19) infection: Video Image

Yasin Kilic, Hakan Usta, Izatullah Jalalzai, Ferhat Borulu and Bilgehan Erkut*

Abstract

Acute pulmonary damage and vascular coagulopathy appear to be frequent in patients with SARS-CoV-2 infection relation to corona-virus. The inflammatory process accompanying the infection and excessive coagulation state is one of the most important causes of patient loss.

Burden and depressive symptoms in health care residents at COVID-19: A preliminary report

Daniela Betinassi Parro-Pires*, Sérgio Henrique de C Matias Barros, Fernanda Sabina HD Araújo, Daniel Zandoná Santos, Luiz Antônio Nogueira-Martins and Vanessa de Albuquerque Citero

Abstract

This paper focuses on the mental health burden on medical and healthcare residents during the 1st wave of COVID-19 pandemic crisis in 2020 describing the activities of a mental health service for residents (NAPREME) in a public university, UNIFESP, Sao Paulo, Brazil; and a pr...

Autoimmune hemolytic anemia in COVID-19 patients, the « transmissible » direct Coombs test

Alice Brochier*, Julien Cabo, Claudine Guerrieri, Leïla Belkhir, Pierre-François Laterre and Véronique Deneys*

Abstract

Background: Like other viruses, the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) appears to be responsible for several autoimmune complications. The occurrence of autoimmune hemolytic anemia has been described in several case reports. This AIHA was also notice...

Phytochemicals candidates as promising preventives and/or curatives for COVID-19 Infection: A brief review

Selma Hamimed*, Nejib Jebli, Rayene Hamimed, Ahmed Landoulsi and Abdelwaheb Chatti

Abstract

The outbreak of new coronavirus acute respiratory disease (SARS-CoV-2) has been a major global challenge for the scientific community to save humanity. While, the unviability of the vaccine keeps most classes of society, especially African countries, suffer from the healthcar...

Evidence-based primary care approach to treating people with COVID-19 infection to prevent life-threatening complications: A review of the evidence for practical application in a clinical setting

Thomas A Sharon*

Abstract

The NIH has published treatment guidelines for treating COVID-19 patients in the hospital. However, as of this writing, there are no established protocols for treating COVID-19 positive patients in primary care. Accordingly, this investigator has taken on the task of reviewin...

Impact of COVID-19 pandemic on anti-microbial resistance and secondary microbial infections

KP Mishra*, Priyanka Mishra, AK Singh and SB Singh

Abstract

Corona Virus Disease-2019 (COVID-19) has become one of the most serious diseases in the history of mankind. It has captured the entire world and solutions are yet to be discovered to fight this global crisis. The outcomes of COVID-19 are influenced by a variety of pre-existin...

COVID-19 New variant and air pollution relationship: how airborne mutagens agent can act on genoma viruses expression: Hypothesis of work

Luisetto M, Naseer Almukthar, Gamal Abdul Hamid, Tarro G, Khaled Edbey, Nili BA, Ghulam Rasool Mashori, Ahmed Yesvi Rafa and Latyshev O Yu

Abstract

Before actual COVID-19 pandemia coronavirus was not so dangerous like now.
In December 2019 - January 2020 in Wuhan first and then in other places this coronavirus was responsible of a first wave of severe pulmonitis responsible of many deaths.

Wuhan and othe...

Living with ‘Long COVID-19’: The long-term complications and sequelae

Vinod Nikhra*

Abstract

Introduction - the perennial pandemic: It is being increasingly realised that the COVID-19 may have become the new reality associated with human existence world over and the mankind may have to live with it for years or even decades. Further, the grievous nature of the diseas...

Comparison of clinical, chest CT and laboratory findings of suspected COVID-19 inpatients with positive and negative RT-PCR

Gokhan Perincek, Canver Onal and Sema Avci*

Abstract

Introduction: COVID-19 is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 and it was first reported in China. The aim of this study was to compare clinical features, chest CT findings and laboratory examinations of suspected COVID-19 inpati...

COVID-19: A unique opportunity for population health to align with nursing schools to help vulnerable populations at risk of adverse outcomes

Eileen Haley, MSN, RN., Victoria Harris, MPH., Parag Agnihotri, MD., Jamie Kwak and Ming Tai-Seale, PhD, MPH*

COVID-19 created a public health crisis shutting down many normal day-to-day activities and adversely affecting life, as we know it.

Exploring COVID-19: Relating the spike protein to infectivity, pathogenicity and Immunogenicity

Vinod Nikhra*

Abstract

Introduction: SARS-CoV-2 life cycle: The disease which reportedly began in Chinese city Wuhan in November-December 2019 manifesting as severe respiratory illness, soon spread to various parts of the world, and was named COVID-19, and declared a pandemic by WHO. The life cycle...

Physical activity can change the physiological and psychological circumstances during COVID-19 pandemic: A narrative review

Khashayar Maroufi*

Abstract

Background: With the outbreak of Coronavirus disease 2019 (COVID-19), many studies’ attention to this world’s complexity increased dramatically. Different views on sports and physical activities have been presented, which have addressed the advantages and disadvan...

PET/MRI, aiming to improve the target for Fractionated Stereotactic Radiotherapy (FSRT) in recurrence of resected skull base meningioma after 2 years: Case report

Sebastião Corrêa*

Abstract

The increasing use of highly conformal radiation deliberates a higher accurate targeting. Contouring and clinical judgment are presumably the crucial point, thus positron emission tomography/magnetic resonance imaging PET/MRI with somatostatin analogs appears to be useful in ...

Seasonal change and COVID-19: Will the harmattan season lead to an increase in COVID-19 cases in Nigeria?

Prince Chiagozie Ekoh*

Abstract

The harmattan season, which is a period characterized by low temperature, dry air and increased air pollution leads to widespread airborne disease and exacerbation of pre-existing conditions, should be recognized as a period of potential risk of high COVID-19 infection rates....

Facing biological risk in child and adolescence neuropsychiatric services during COVID-19 outbreak: Management of protection levels for the direct access

Teresa Sebastiani, Carlo Di Brina, Maria L Tossali*, Morena Tafuro and Marco Marcelli

COVID-19 emergency requests a new definition of security procedures adopted in Child and Adolescence Neuropsychiatric Services (CANS).

Hypertension and sex related differences in mortality of COVID-19 infection: A systematic review and Meta-analysis

Probir Kumar Ghosh*, Mohammad Manir Hossain Mollah, ABM Alauddin Chowdhury, Nazmul Alam and Golam Dostogir Harun

Abstract

Background: Hypertension is the leading cause of cardiovascular diseases and premature deaths. Hypertension plays a striking role in mortality and morbidity in case of Coronavirus Disease 2019 (COVID-19) infection; however, numerous studies have reported contradictory finding...

Ivabradine versus carvedilol in the management of palpitation with sinus tachycardia among recovered COVID-19 patients

Kartik Pandurang Jadhav* and Pankaj V Jariwala

Abstract

Introduction: One of the major complications among COVID-19 patients include cardiac arrhythmias. Commonest arrhythmia is sinus tachycardia which is usually associated with palpitation causing discomfort to patients. In this study, we present a comparative st...

Stages in COVID-19 vaccine development: The Nemesis, the Hubris and the Elpis

Vinod Nikhra*

Abstract

The nemesis: SARS-CoV-2 pandemic: Leaving in its wake millions of infections, accompanied by an immense magnitude of morbidity and multitude of mortality, and an unfathomable economic toll, the COVID-19 pandemic has led to a global calamity. An effective and safe COVID-19 vac...

Assessment of knowledge, practice and associated factors towards prevention of novel corona virus among clients attending at Debre Tabor General Hospital, Debre Tabor Town, North West Ethiopia, 2020: Institutional based cross-sectional study

Tigabu Desie Emiru*, Tekalign Amera Birlie, Sheganew Fetene Tasew, Abraham Tsedalu Amare, Nigusie Selomon Tibebu and Chalie Marew Tiruneh

Abstract

Background: Corona virus disease is a highly infectious disease caused by the newly innovated corona virus. An emerging respiratory disease was abbreviated as COVID-19, after it has been first reported in December 2019 in Wuhan city of China. Ethiopia Ministry of health initi...

How the COVID-19 outbreak affected physician-patient relationship

Ali Fakhari, Roya Dolatkhah and Keivan Fakhari Dehkharghani

Abstract

Physician-patient communication is the most basic element and vital skill of physicians in the diagnosis, treatment, and establishing diagnostic protocols. As the risks of contagion and viral infection are higher in physicians and health workers, front line soldiers inpatient...

Spontaneous pneumomediastinum associated with COVID-19: Rare complication of 2020 pandemic

Arnaldo A Nieves-Ortiz*, Vanessa Fonseca-Ferrer, Kyomara Hernández-Moya, Keren Mendez Ramirez, Jose Ayala-Rivera, Marangely Delgado, Juan Garcia-Puebla, Rosangela Fernández-Medero and Ricardo Fernandez-Gonzalez

Abstract

Spontaneous pneumomediastinum (SPM) is a rare condition, more commonly seen in patients with history of asthma, chronic obstructive pulmonary disease, infections, or drug users. Today, we face one novel virus that has cause an outbreak of acute respiratory illness, affecting ...

Galenic hospital laboratory during COVID-19 emergency: A practical experience in an advanced country

Fiazza C, Ferraiuolo A, Luisetto M* and Ram Sahu

Abstract

In the actual COVID-19 emergency, as pandemic disease, in many countries at the same time there was the rapid need to use preventive and therapeutic measures to control the diffusion of infection.

In PC AREA (Italy north) in the period between March and May 2020, in...

Reactive Oxygen spray as prophylaxis for COVID-19 infection

Matthew Dryden*, Stephen Kidd, Nathan Moore and Afroze Khan

Viral transmission of SARS-CoV-2, the virus causing COVID-19 is very high within households despite self isolation [1,2]. Transmission of the virus is thought to be similar to that of influenza.

Packaging challenge for COVID-19 drug

Anupam Chand*

At present Corona virus is the most burning topic across the world. At present there is no drug available to cure 100%. So many companies are trying to make it possible as soon as they can.

SARS-CoV-2 infection and phylogenetic analysis with the risk factors in human body alongside the pulmonary effects and medication

Ahnaf Ilman*, Mauro Luisetto, Ahmed Yesvi Rafa, Naeem Musa, Md. Abu Syed, Sabit Ibtisam Anan and Tazwan Haque

Abstract

Related the extremely transmittable abilities of SARS-CoV-2,a harmonious virus to the bat CoV, gets transmitted by three principal processes-- the inhalation of droplets from the SARS-CoV-2 infected person, contacting to the person, and by the surfaces and materials defiled w...

COVID-19 related rhabdomyolysis

Alejandro Munoz-Martinez, Maham Akbar Waheed, Kenar D Jhaveri and Geurys Rojas-Marte*

A novel coronavirus known as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) with a high rate of human-to-human transmission has emerged, resulting in a worldwide public health crisis of catastrophic proportions. Common initial symptoms of Coronavirus Disease 2019 (COVID-19) include ...

Liver disease in the Era of Coronavirus Disease 19 (COVID-19) pandemic

Siddesh Besur*, Rehana Begum, Vikraman Gunabushanam and Herbert L Bonkovsky

Coronavirus infections have caused outbreaks in humans: SARS-COV ((Severe Acute Respiratory Syndrome) and MERS-CoV (Middle East Respiratory Syndrome) resulting in significant mortality and morbidity.

COVID-19 and taking care and protection of patients with intellectual disabilities, need special care and equity

Faheem Anwar, Muhammad Tayyab*, Jawad Khan and Ihteshamul Haq

Since December 2019, entire world is facing problem of corona-virus pandemics and its impact on the people and their social life has been phenomenal.

Anti COVID-19 immunity developed as assessed in a community-based oncological center

Teresa Guix, Marco Panichi, Ines Guix, Iván García, Carles Llebaría, Nicolás Achkar, Luis Quinzaños, Hamza Sentisi, Jose Luís Enríquez, Ana Galván, Cristina Pérez-Sánchez, Víctor González, Carmen León and Benjamín Guix*

Abstract

Introduction: Serology (antibody) tests for the SARS-CoV-2 have been proposed as an instrument to inform health authorities about immunization during the COVID-19 pandemic. As there is a significant part of the population that may have some degree of immunity, it is of great ...

COVID-19 pandemic, recurrent outbreaks and prospects for assimilation of hCoV-19 into the human genome

Vinod Nikhra*

Abstract

The outbreaks and resurgence: The disease which reportedly began in the Chinese city Wuhan in November-December 2019, soon spread to various parts of the world, and was named and declared a pandemic disease by WHO. While the European countries were recovering from the epidemi...

Emergency care sick palliative and problems oncology in emergency department during the COVID-19 pandemic

Basri Lenjani*, Nehat Baftiu*, Premtim Rashiti, Gani Shabani, Blerim Krasniqi, Arber Demiri, Besarta Pelaj, Fllanza Spahiu, Arban Demi and Dardan Lenjani

Abstract

Emergency medical care in palliative patients during the COVID-19 pandemic, it is important to provide a consistent treatment for stable patients that should be consistent with the goals and benefits, the perspective of these patients, but avoiding palliative patients with a ...

Coronaryvirus infection, oxidative stress in ENT

Holeček V* and Rokyta R

In COVID-19 pandemic we focused on epidemiology and somewhat we neglect the possibility of biochemical influencing of the infection. Therefore we try to find some properties of the virus, which are impressionable by drugs. Droplet infection transmission is mainly (hypochloric acid) by nose and mo...

Acute kidney injury in colombian patients with COVID-19 who received kidney support therapy with genius® 90 technology

Emilio Rey-Vela, Jesús Muñoz, Jorge Rico-Fontalvo, Rodrigo Daza-Arnedo, Katherin Portela-Buelvas, Nehomar Pájaro-Galvis, Víctor Leal-Martínez, Emilio Abuabara-Franco, José Cabrales-Juan, Leonardo Marín, Lucas Daza, Samuel Cuadro, Emir Ortiz, María Raad-Sarabia, Cesar Ferrer, Alejandra Prada, Greisy González, Elkin Mendoza, Klearly Tinoco, Jorge Camacho, Joel Ortega, Carlos Tobón, Juan Montes, Jorge Coronado, Luis Salgado-Montiel, José Correa, Fabio Salas, Amilkar Almanza-Hurtado and Miguel Aguilar-Schorborg

Abstract

Introduction: Acute kidney injury (AKI) is one of the complications associated with severe COVID-19 infection, and it can present in up to 20% to 40% of the cases; of these, approximately 20% will require renal replacement therapy (RRT).

Objective: ...

The expected second wave of COVID-19

Madiha Asghar* and Misbahud Din

The pandemic of Coronavirus Disease (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) continues to rise around the globe. As per 15th July 2020, the World Health Organization (WHO) reported 13,119,239 confirmed COVID-19 cases along with 573,752 confirmed deaths glo...

COVID-19 disease with persistently negative RT-PCR test for SARS-CoV-2

Sánchez Ríos Carla Paola*, Jiménez Cabrera Oscar Gabriel, Oropeza Lutzow Rebeca, Vázquez Rojas Hazel, Barreto Rodríguez José Omar, Guzmán-Casta Jordi, Guzmán-Huesca Jorge, Riera-Sala Rodrigo and Centeno Sáenz Gustavo Iván

Summary

Introduction: The disease outbreak of COVID-19 has had a great clinical and microbiological impact in the last few months. In the preanalytical phase, the collection a sample from of a respiratory tract at the adequate moment and from the correct anatomical si...

Estimating global case fatality rate of coronavirus disease 2019 (COVID-19) pandemic

Manisha Mandal and Shyamapada Mandal*

Abstract

Background: There is a huge global loss of lives due to COVID-19 pandemic, the primary epicentre of which is China, where the causative agent of the disease, SARS-CoV-2 was first emerged in December 2019. This study aims to explore the severity, in terms of c...

Zn2+ Ions-Immune Virucidal activities for children and adults with preventions against 2019-nCoV and COVID-19 infection

Tsuneo Ishida*

Abstract

Zinc induced pediatric preventing respiratory 2019-nCoV is required that supplementation with zinc gluconate 20 mg in Zn deficient children resulted in a nearly twofold reduction of acute lower respiratory infections as well as the time to recovery. Zinc supplementation in ch...

Health professional stress during COVID-19 pandemic

Fatiha Bennaoui*, Nadia Ei Idrissi Slitine and Fadl Mrabih Rabou Maoulainine

Abstract

WHO declared the coronavirus disease 2019 (COVID-19) outbreak, caused by SARS-CoV-2, to be a pandemic on March 12, 2020. In Morocco, the first case was reported in March 2nd 2020. The mental health of general population, medical and nursing staff especially has been greatly c...

COVID-19 associated hyperthyroidism due to destructive thyrotoxicosis in a young female patient

Zeilberger MS*, Hasmann SE*, Auer MK and Schmidmaier R

Abstract

SARS-CoV2 can induce multiple immunological and endocrinological changes. We report the case of a COVID-19 associated hyperthyroidism in a young female.

Per definition the patient – because of having given birth six weeks previously - had a postpartum thyroidi...

A Comprehensive review on genomic diversity and epidemiology of COVID-19

Zeshan Haider Raza*, Muhammad Ahmed Ihsan, Sahrish Khan, Haroon Zafar and Tayyaba Rehman

Abstract

A respiratory outbreak of COVID-19 started from Wuhan, China and on 30 January 2020, WHO declared this infection to be epidemic, implementing public health emergency worldwide. On 11th March 2020, observing its prevalence in the whole world and WHO declared as a pandemic. Man...

Statistical and equation model analysis on COVID-19

Bin Zhao* and Jinming Cao

Abstract

Background: An infectious disease caused by a novel coronavirus called COVID-19 has raged across the world since December 2019. The novel coronavirus first appeared in Wuhan, China, and quickly spread to Asia and now many countries around the world are affect...

Uterine Fibroid Embolization in time of Covid-19

Nestor Kisilevzky* and John C Lipman

The coronavirus pandemic has caused major changes in society around the world, especially in healthcare systems. Patients with various medical ailments and conditions who were scheduled to undergo elective treatments before the pandemic arrived, wonder now if they still should follow through with...

COVID-19 in pregnancy: Our experience at a tertiary maternity unit in France

Darido Jessie*, El Haddad Cynthia, Diari Jed, Grevoul Fesquet Julie, Bouzid Nassima, Bobric Andrea, Lakhdara Nefissa, Bazzi Zeinab, Lebis Cindy, Khadam Louay and Rigonnot Luc

Abstract

Objectives: Our main objectives are to reveal the pregnancy and neonatal impacts of COVID-19 infection and to compare it to the results that are reported in the literature.
Methods and materials: The characteristics of the admitted pregnant patients CO...

Why are more otorhinolaryngology surgeons dying from Covid-19 than any other surgical specialty?

Daryll Baker*

Covid-19 infection is caused by the coronavirus SARS-CoV-2. This has resulted in the present pandemic from which thousands of people have died including many front-line health care workers. Of the surgeons who have died from covid-19 it would appear that otorhinolaryngology surgeons have made the...

The rising role of mesenchymal stem cells in the treatment of COVID-19 infections

Al-Anazi KA* and Al-Jasser AM

Infectious diseases are a leading cause of death worldwide [1,2]. The Mid-20th century witnessed most of the antimicrobial discoveries but recently there is dramatic shortage of new classes of antimicrobial agents due to failure to build a sustainable antimicrobial discovery platform [1-4]. For e...

Review on impacts of COVID-19 pandemic on life animals and dairy product processing industries of the world

Lammifyad Chimde*

Abstract

This review was conducted for the objective of assessing causes of COVID-19 pandemic impacts on life animals and dairy product processing industry of the world. Since its outbreak in Wuhan town of China, the newly emerged strains of corona virus COVID-19 causes incredible cri...

Inhaled statins to combat COVID-19 – prophylactic and treatment approach

Archana P Iyer* and Maryam A Al-Ghamdi

The coronavirus disease 19 (COVID-19) is a highly transmittable and pathogenic viral infection caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which emerged in Wuhan, China and spread around the world (WHO, 2020). The genome of the SARS-CoV-2 has been reported over 80% ide...

Can house flies mechanically carry and/or transport sars-cov-2?

Alfredo Montes*, Wilfrido Coronell and Rosa Baldiris

Abstract

The new coronavirus SARS-CoV-2 that causes different infections in humans has become a challenge for humanity because it has caused many deaths worldwide. This new virus is considered as a zoonotic infectious particle, the clear mechanisms of the pathogenicity and transmissib...

COVID-19: The possible medical strategies

Mohamed SA Mohamed*

Abstract

In late 2019, a pandemic crisis started in Wuhan, China, swept the whole world. The disease is caused by the SARS-CoV-19 virus that belongs to the corona family of viruses. The virus mainly caused failure of respiration, and led to many deaths worldwide. The main focus of res...

Effective COVID-19 prevention and control in areas of ultra-dense population: Lessons from Macau SAR

Xueni Bian, Lan Yao and Ying Bian*

Abstract

In this paper we summarise, in chronological order, all COVID-19 preventive measures undertaken by the Macau Special Administrative Region (SAR) government during the first quarter of 2020. The information and narrative contained herein may be of useful to other parts of the ...

Management of gestational diabetes during ‘COVID19 time’

Nicolina Di Biase*

Abstract

The measures put in place by many governments around the world to fight the spread of COVID-19 have drastically reduced visits to diabetes centres. To keep providing people with diabetes the professional support they need and reduce the inconvenience caused by the interruptio...

Contemporary learning or E-Learning in physiotherapy, pre and post COVID-19: Short communication

Mohammed Suhail*, Sharath C and Akhil Mathew

Since December 2019, an outbreak of novel corona virus disease was reported in Wuhan, which has subsequently affected more than 160 countries worldwide. The ongoing outbreak has been declared as a pandemic by WHO, a global public health emergency. Several countries are successfully fighting with ...

Role of nanotechnology in diagnosing and treating COVID-19 during the Pandemic

Abdul Waris, Muhammad Ali, Atta Ullah Khan, Asmat Ali and Abdul Baset*

Abstract

The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), began in December 2019 in Wuhan, China. To date, the virus has infected roughly 5,000,000 people and caused approximately 345,000 deaths worldwide, an...

Identifying patterns in COVID-19: Morbidity, recovery and the aftermath

Vinod Nikhra*

Abstract

The infectivity and pathogenesis: SARS-CoV-2, the causative agent of Covid-19, involves Angiotensin-converting enzyme 2 (ACE2) receptors on type II alveolar type 2 (AT2) cells in lungs. Apart from, the upper and lower respiratory tracts, the disease affects the...

COVID-19: Targeting the cytokine storm via cholinergic anti-inflammatory (Pyridostigmine)

Ahmed H Osman*

Abstract

Background: The development of COVID-19 having been set apart as the third presentation of an exceptionally pathogenic coronavirus into the human populace after the extreme intense SARS-COV and MERS-COV in the twenty-first century. The infection itself doesn&...

South Asia is more vulnerable to COVID-19 pandemic

Hom Nath Chalise*

Coronavirus disease 2019 (COVID-19) which originated in China spread progressively all over the world [1]. On 11th March 2020 WHO declared COVID-19 outbreaks as a pandemic [2].

Case reports of observed significant improvement in patients with ARDS due to COVID-19 and maximum ventilatory support after inhalation of sodium bicarbonate

Wardeh A*, Conklin J and Ko M

The emergence of COVID-19 worldwide in an unprecedented pandemic. COVID-19 has a significant mortality, mostly from acute lung injury. We reviewed the available literature from China and Europe in regard to the behavior of SARS-Cov2 and ability to adhere to the cell wall [1,2]. The evidence based...

Exploring pathophysiology of COVID-19 infection: Faux espoir and dormant therapeutic options

Vinod Nikhra*

Abstract

COVID-19 virus structural components: The 2019-nCoV, also called SARS-CoV-2, was first reported in Wuhan, China in December 2019. The disease was named Coronavirus Disease 2019 (COVID-19) and the virus responsible for it as the COVID-19 virus, respectively, b...

Yemen is free of COVID-19

Hussein O Kadi*

Among all the countries, Yemen is free of corona virus, and no single case has been recorded till today. Yemen is characterized by its mother geographical location on the Red Sea and its population is approximately 30 million people and an area of ​​555,000 square kilometers.

Neutrophils, NETs, NETosis and their paradoxical roles in COVID-19

Al-Anazi KA*, Al-Anazi WK and Al-Jasser AM

Abstract

The pandemic of COVID-19 has adversely affected the world in many aspects. The health and economic sectors suffer most of the repercussions of this disease. The search for a cure for this rapidly spreading virus which is causing massive life losses worldwide requires clear un...

8 Gy single dose radiotherapy for bone metastasis in COVID-19 pandemia period: Review

Bora Uysal*, Hakan Gamsız, Ferrat Dincoglan, Omer Sager, Selcuk Demiral and Murat Beyzadeoglu

Abstract

Bone metastases in cancer patients are highly painful and decrease the quality of life for these group of population. Covid-19 pandemia is a global challenging issue that mostly affect the patients with immune suppression or having comorbid diseases older than 65 years old. T...

Implications on mental health by the coronavirus disease 2019 (COVID-19) pandemic: The role of general practitioner

Jose Luis Turabian*

Abstract

Coronavirus disease 2019 (COVID-19) pandemic gives rise to a significant number of psychological consequences and health problems. The GP must recognize the feelings generated in their patients and address them. This task includes 4 areas: 1. Knowing and managing the epidemic...

Problems shared in psychiatry helpline of a teaching hospital in eastern Nepal during COVID-19 pandemic lockdown

Dhana Ratna Shakya*

Abstract

COVID-19 pandemic soon apparently proved to be havoc and a great stressor. During such a stressful time, mental health is in threat. Here, we intend to review the presenting problems/ symptoms as shared in psychiatry helpline of a Teaching Hospital in eastern Nepal during the...

COVID-19 situation in Nepal

Hom Nath Chalise*

Coronavirus disease 2019 (COVID-19) which first appeared in China spread gradually all over the world within three months [1]. China was the only country mainly affected by Covid-19 until February 2020, but from the beginning of March, the disease started to spread rapidly to South Korea. It reac...

The Psychology of the Common Cold and Influenza: Implications for COVID-19

Andrew P Smith*

Abstract

Research on psychological risk factors for upper respiratory tract illnesses (URTIs) has been conducted for over fifty years. Early studies failed to control for exposure and also often relied on self-report rather than clinical and virological assessment. A universal policy ...

The Trans-zoonotic Virome interface: Measures to balance, control and treat epidemics

Vinod Nikhra*

Abstract

The global virome: The viruses have a global distribution, phylogenetic diversity and host specificity. They are obligate intracellular parasites with single- or double-stranded DNA or RNA genomes, and afflict bacteria, plants, animals and human population. T...

Hypothesis about pathogenic action of Sars-COV-2

Marasco Daniela, Del Prete Salvatore* and Sabetta Rosalaura

Abstract

The Hypothesis born on a simple clinical data noted by some Chinese Reserchers during the starting point of epidemic began in the dicember of the 2019, for the novel member of human coronavirus, officially named as SARS‐CoV‐2 (severe acute respiratory syndrome coronavirus...