Letter to the Editor

Serum MicroRNA-155 in Acute Graft-Versus-Host-Disease (aGVHD)

Allogeneic hematopoietic stem cell transplant (alloHSCT) is a curative treatment for many hematologic malignancies. Unfortunately, about  30-50% of all recipients undergoing alloHSCT develop acute graft-versus-host-disease (aGVHD), which is associated with high morbidity and mortality [1,...

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Research Article

The effects of a clinical ladder program on professional development and job satisfaction of acute care nurses

Nurses play a vital role in acute care hospitals and health care delivery. The purpose of this research study is to identify the nurse’s perception of the Clinical Ladder Program at their hospital and the correlation it has on the nurse’s job satisfaction and their professional dev...

Read Full Article HTML DOI: 10.29328/journal.cjncp.1001016 Citation

Research Article

Longitudinal and transverse dimensions of Hypertrophied Cardiomyocytes in human Left Ventricle (LV) at autopsy; Heart failure might result from changes in chamber geometry without contractile weakening

The shapes and sizes of human cardiomyocytes are accessible to systematic observation under most circumstances only at autopsy. This constraint has seriously curbed the study of these topics, thereby leaving a crippling gap in our understanding of heart failure. In recent years the only publis...

Read Full Article HTML DOI: 10.29328/journal.apcr.1001013 Citation

Review Article

Update on Phenobarbital for Alcohol Withdrawal Syndrome in Intensive Care

Alcohol abuse is a global health problem. Alcohol withdrawal syndrome (AWS) ranges from mild to severe symptoms that can lead to fatal delirium tremens requiring ICU admission and incurring high health care cost as high as $20,000 a month.

Read Full Article HTML DOI: 10.29328/journal.jcicm.1001023 Citation

Review Article

Long-term clinical outcome of minimally invasive versus open single-level transforaminal lumbar interbody fusion for degenerative lumbar diseases with a minimum follow-up of 2 years: A meta-analysis protocol

Introduction: Minimally invasive surgical transforaminal lumbar interbody fusion (MIS-TLIF) is a relatively new approach for fusion of the lumbar spine. It was developed in addition to traditional open transforaminal interbody fusion (OTLIF) to minimize iatrogenic soft tissue ...

Read Full Article HTML DOI: 10.29328/journal.jnnd.1001021 Citation

Research Article

High water intake in preventing the risk of Uric Acid Nephrolithiasis: A systematic review and meta-analysis

Background: Hyperuricosuria, persistently low urinary pH, and low urinary volume are the main risk factors of uric acid nephrolithiasis. Epidemiologic studies suggest that high water intake is protective against the occurrence of symptomatic kidney stone events of all types. T...

Read Full Article HTML DOI: 10.29328/journal.jcn.1001038 Citation


Proposal for the elimination of allergies

A man I knew had an extreme allergy to poison ivy when he was a child. When he was about four-teen, he was hanging out with a group of his friends who dared him to eat some poison ivy. He did, and never got poison ivy again. Presumably, the ingestion of the allergen led to the development of i...

Read Full Article HTML DOI: 10.29328/journal.icci.1001010 Citation

Research Article

A forensic treatment-monitoring study of an adult with attentiondefi cit disorder with hyperactivity and substance use disorder

Background: The patient in this study experienced a childhood marked by confl icts within the family, physical abuse, frequent changes of school settings, truancy, and unspecifi ed learning disabilities. After leaving school at age 17, she was chronically depressed, had anger ...

Read Full Article HTML DOI: 10.29328/journal.jatr.1001009 Citation

Research Article

Non-chemical control of Armillaria mellea infection of Prunus persica

Peaches, Prunus persica were planted as grafted saplings in an avocado orchard previously infested with Armillaria mellea (Vahl) P.Kumm. Trees were planted in large or small holes with or without fresh yardwaste chips added as an amendment and with or without a Trichoderma bi...

Read Full Article HTML DOI: 10.29328/journal.jpsp.1001031 Citation

Case Report

Glomus Tumor of the Scrotum: A Case Report

Glomus tumors are rare, usually benign, lesions that arise most often in the
extremities. They are derived from the glomus body and have a propensity to be found in the fingers and toes, and often in the subungual area [1]. They typically demonstrate pinprick sensitivity, cold hypersen...

Read Full Article HTML DOI: 10.29328/journal.jro.1001028 Citation

Review Article

Connected Health Apps and Devices: Implications for Healthcare Delivery

Healthcare is realizing the importance of health information technology - its applications and devices in play today. Advancing healthcare best practices will rely on up to date data and analysis to provide the most effective forms of therapy. Healthcare is becoming more reliant on patients wh...

Read Full Article HTML DOI: 10.29328/journal.cjncp.1001014 Citation

Review Article

Utilizing Pulsed Electromagnetic Field (PEMF) Therapy (Diapulse®) for Drug- Free Pain Management to Eliminate Reliance on Opioids for Non-Malignant Chronic Pain: A literature Review and Proposal for Pilot Study

The Federal and State governments have declared the presence of an opioid addiction pandemic in the United States claiming the lives of more than 55,000 in 2015 (Rudd RA, Seth P, David F and Scholl L. 2016). The pharmaceutical manufacturers of the numerous FDA-approved opioid
drugs are...

Read Full Article HTML DOI: 10.29328/journal.cjncp.1001013 Citation

Research Article

Assessing the stand size of bay trees (Persea spp.) after exposure to laurel wilt disease in a North Florida Preserve

Although laurel wilt disease was first reported in the United States in 2002 from redbay trees (Persea borbonia) around Savannah, Georgia it has rapidly spread throughout the southeastern coastal plain including Georgia and Florida. In the current study, transects were used to assess the sprea...

Read Full Article HTML DOI: 10.29328/journal.jpsp.1001030 Citation

Mini Review

Handwashing in healthcare today: Why haven’t we gotten better?

In 2010, a study identified that only about 40 percent of doctors and other health care providers comply with proper hand hygiene techniques in hospitals and other healthcare facilities. These statistics are alarming as healthcare professionals are the ones who set the gold standard for hygien...

Read Full Article HTML DOI: 10.29328/journal.cjncp.1001011 Citation

Letter to the Editor

Do you really want to improve the results of treatment for acute pneumonia?

The question raised in the title of this letter is a natural consequence of the findings and conclusions that have been growing steadily in recent years regarding the results of treatment for acute pneumonia (АР). If you look at the publications of recent years in this field of medicine, it ...

Read Full Article HTML DOI: 10.29328/journal.jcicm.1001021 Citation

Case Report

Rosai-Dorfman disease presenting as a breast mass

Rosai-Dorfman disease (RDD) is an idiopathic, benign proliferation of histiocytes that can be present in multiple organs such as lymph node, skin, soft tissue, orbit, central nerve system and bone; however, it rarely occurs in the breast. In general, RDD is a painless, firm and poorly defined ...

Read Full Article HTML DOI: 10.29328/journal.apcr.1001012 Citation

Research Article

Are S-Klotho’s Maximal concentrations dependent on Exercise Intensity and Time in young adult males?

The purpose of the present study was to define the period of time in which aerobic training does not increase further serum S-Klotho levels in untrained young adult males, and to examine the relation between plasma S-Klotho concentration and maximal oxygen uptake (VO2max).

Read Full Article HTML DOI: 10.29328/journal.jccm.1001033 Citation

Case Report

Hypocomplementemic interstitial nephritis with long-term follow-up

Prednisone-sensitive hypocomplementemia, renal insuffi ciency, and kidney biopsy demonstrating severe tubulointerstitial nephritis (TIN), storiform fi brosis, and tubulointerstitial immune deposits are typical of IgG4-related tubulointerstitial nephritis and hypocomplementemic interstitial nep...

Read Full Article HTML DOI: 10.29328/journal.jcn.1001024 Citation

Research Article

Angioarchitectonics of acute pneumonia

The article presents the results of x-ray anatomical studies of 56 whole lung preparations, which were carried out immediately after the autopsy of children who died from АP. In 47 cases it was carried out the contrast of the vessels and in 9 cases the bronchial tree. The results allowed

Read Full Article HTML DOI: 10.29328/journal.jcicm.1001020 Citation

Research Article

Acute pneumonia: Facts and realities against etiological hypotheses and beliefs

Modern AP concepts are focused exclusively on the infectious nature of the disease and the presence of certain pathogens. This belief determines the principles of treatment, the lack of effectiveness of which remains a concern of health professionals. The article presents a fragment of the stu...

Read Full Article HTML DOI: 10.29328/journal.jcicm.1001019 Citation

Research Article

Anti-Inflammatory probiotic biomarkers in Fermented foods

We present below a mechanistic molecular approach for development of Anti-Inflammatory biomarkers of Probiotic Bacteria in Fermented Foods. Probiotics are live microorganisms that promote human health by counteracting the noxious toxic gut microfl ora in human intestine,
by modulating ...

Read Full Article HTML DOI: 10.29328/journal.jcn.1001023 Citation


Navigation in the land of Scarcity

Delivering health care is a complex task that marginalized a portion of the
population intentionally or unintentionally. Discrepancy in health care providing to the intended patients is sometimes accompanied by unintended collateral damage to the bystanders who desperately needing our ...

Read Full Article HTML DOI: 10.29328/journal.avm.1001007 Citation

Research Article

Peaceful Bridging

In our past 200 years we have seen the advancing development of Dental Arts and Science though discoveries by its practitioners. Perhaps it will do some good to review the basis upon which fixed tooth replacement has evolved—that is the prosthetic crown.

Read Full Article HTML DOI: 10.29328/journal.johcs.1001025 Citation


Is there an ideal blood pressure during cardiopulmonary bypass to prevent postoperative cerebral injury? – What does the recent evidence say?

Post cardiac surgery stroke is a devastating complication with an incidence as high as 50%1. The association between intra-operative mean arterial blood pressure (MAP- better called linear blood pressure) during cardiopulmonary bypass (CPB)
and the development of postoperative stroke-a...

Read Full Article HTML DOI: 10.29328/journal.jccm.1001031 Citation

Research Article

Effects of intraoperative epidural anesthesia during hepatectomy on intraoperative and post-operative patient outcomes

Objective: The objective of this study was to evaluate the effects of intraoperative epidural anesthesia combined with balanced general anesthesia on intraoperative hemodynamics and fl uid requirement, and
on postoperative patient outcome

Read Full Article HTML DOI: 10.29328/journal.ijcar.1001008 Citation

Case Report

Preventing Peri-implantitis with a proper Cementation Protocol and with the consideration of alternatives to Cement-Retained Implant Restorations

Successful implant restoration is depending on an adequate surgical and prosthetic protocol. In the last few years an increase in Peri-Implantitis has been attributed, in part, to the excess cement left around the implant collar and threads, leading in many cases to bone loss and even the comp...

Read Full Article HTML DOI: 10.29328/journal.jcad.1001007 Citation


Functional Electrical Stimulation (FES): Clinical successes and failures to date

Non-invasive electrical stimulation in the form of neuromuscular electrical stimulation (NMES) and functional electrical stimulation (FES) has been documented as an optional assessment and treatment technology for decades.

Read Full Article HTML DOI: 10.29328/journal.jnpr.1001022 Citation

Short Communication

Synthesis and Biological Evaluation of Fluorescein-Tagged 1-Methyl-o-carborane for Boron Neutron Capture Therapy

Fluorescein was conjugated with 1-methyl-o-carborane and the resulting bioconjugate was biologically evaluated through microscopic and flow cytometric studies in pancreatic cancer and squamous cell carcinoma cell lines.

Read Full Article HTML DOI: 10.29328/journal.aac.1001016 Citation

Research Article

Percentage of Positive Biopsy Cores Predicts Presence of a Dominant Lesion on MRI in Patients with Intermediate Risk Prostate Cancer

Background: Biopsy findings of percentage of positive biopsy cores, percentage of cancer volume, and maximum involvement of biopsy cores have been shown to have prognostic value and correlate with magnetic resonance imaging (MRI) findings of extracapsular extension and seminal...

Read Full Article HTML DOI: 10.29328/journal.jro.1001025 Citation


Knowledge or Money: Which One is More Important?

When I asked the students in my general Chemistry class whether grade is more important than knowledge, a majority of them opted for grades over knowledge and this answer did not surprise me a bit as the smart phones are available for them to think while their brains are corrupted or unused fo...

Read Full Article HTML DOI: 10.29328/journal.aac.1001015 Citation

Research Article

What is the Cost of Measuring a Blood Pressure?

Rationale: Blood Pressure measurement has transitioned to the oscillometric method in most hospitals in the United States, however out-patient offi ces mainly use the auscultatory technique.

Read Full Article HTML DOI: 10.29328/journal.ach.1001012 Citation


Use of Rivaroxaban and Apixaban, Two Non-Vitamin K Antagonist Oral Anticoagulants (NOACs), in Renally Impaired Patients - the limits of our knowledge

Patients with chronic kidney disease are at increased risk of thromboembolic
complications and are therefore often managed with anticoagulation therapy [1]. While
these patients are traditionally treated with Vitamin K antagonists (VKAs), the Non-
Vitamin K antagonist o...

Read Full Article HTML DOI: 10.29328/journal.jccm.1001026 Citation

Review Article

Vigour of CRISPR/Cas9 Gene Editing in Alzheimer’s Disease

Ailment repairing regiments has turn out to be arduous, despite a plenty of understanding and knowledge acquired in the past relating to the molecular underpinnings of Alzheimer’s disease (AD. Umpteen clinical experiments targeting the fabrication and accumulation have been turned fruitl...

Read Full Article HTML DOI: 10.29328/journal.jnnd.1001014 Citation

Research Article

Impact of four obesity interventions on biometric measures of individuals positive and negative for food addiction

Obesity is a major contributor to ill health and numerous comorbidities globally. Recent studies suggest that addictive-like tendencies toward foods, especially highly processed foods, contribute to this epidemic.

Read Full Article HTML DOI: 10.29328/journal.apmh.1001002 Citation

Research Article

Adaptive planning and toxicities of uniform scanning proton therapy for lung Cancer patients

Purpose: Adaptive planning is often needed in lung cancer proton therapy to account for geometrical variations, such as tumor shrinkage and other anatomical changes.

Read Full Article HTML DOI: 10.29328/journal.jro.1001023 Citation

Historical Vignette

Dr. Saul Hertz Discovers the Medical Uses of Radioiodine (RAI)

Primary sources document Dr. Saul Hertz (1905 - 1950) as conceiving and developing radioiodine (RAI) as a diagnostic tool and as a therapy for thyroid diseases. Dr. Hertz was the first and foremost person to develop the experimental data on RAI and apply it to the clinical setting.

Read Full Article HTML DOI: 10.29328/journal.jro.1001022 Citation

Review Article

Anesthetic considerations for endovascular repair of ruptured abdominal aortic aneurysms

Ruptured abdominal aortic aneurysm (rAAA) carries high morbidity and mortality. Advances in endovascular techniques in the last two decades allow for minimally invasive approach for repair of these aneurysms. A
succinct but comprehensive pre-operative is essential for delivery of a saf...

Read Full Article HTML DOI: 10.29328/journal.avm.1001005 Citation

Case Report

A case report of Hypocomplementemic urticarial vasculitic syndrome presenting with Renal failure

We present a case of hypocomplementemic urticarial vasculitic syndrome (HUVS) who developed severe renal failure requiring ICU-level care. Our patient is a 66-year-old man who presented with abdominal pain, rash, confusion, oliguria, and shortness of breath. He was found to be in acute renal f...

Read Full Article HTML DOI: 10.29328/journal.jcn.1001017 Citation

Research Article

Three year outcomes following positive cross match renal transplantation despite failure to convert to Negative Flow Cross Match after Desensitization

Desensitization allows successful transplantation of patients with a positive crossmatch (PXM) against their live donor. We evaluated outcomes following PXM renal transplant despite failure to convert to negative flow cytometric crossmatch (FCXM) after desensitization.

Read Full Article HTML DOI: 10.29328/journal.jcn.1001016 Citation

Case Report

Congenital poisoning after maternal parenteral mercury administration

This is the case of a full-term baby girl, born to a mother with a history of parenteral inorganic mercury administration. Thirteen years prior, this mother injected 1mL of inorganic mercury in her right forearm, was subsequently hospitalized, but never received chelation treatment. Her first ...

Read Full Article HTML DOI: 10.29328/journal.japch.1001001 Citation

Research Article

Preliminary Report on the Effect of Mesenchymal Stem Cell Therapy in Patients with Chronic Lung Allograft Dysfunction

Background: Mesenchymal stem cell (MSC) effects can shift immune responses toward anti-inflammatory and tolerogenic phenotypes, potentially helping patients with bronchiolitis obliterans syndrome (BOS).

Read Full Article HTML DOI: 10.29328/journal.jsctt.1001012 Citation

Review Article

Cyberbullying: A narrative review

A literature search was conducted using PubMed and PsycINFO to locate cyberbullying research that was published during the last 4 years. In this narrative review, cyberbullying research is briefly summarized and critiqued. The review is focused on the varying definitions and characteristics of...

Read Full Article HTML DOI: 10.29328/journal.jatr.1001007 Citation

Review Article

Neurobiology of Common Sleep Disorders

Sleep disorders in human are common and detrimental to general health of all age groups. While the neurobiological mechanisms of sleep disorders are not yet fully understood, recent advances in research on the sleep-wake regulation mechanism, genetic and epigenetic factors, cognitive,..

Read Full Article HTML DOI: 10.29328/journal.jnnd.1001013 Citation

Review Article

Parental Role in Adolescent Substance Abuse Prevention

Background: There is a huge gap in the U.S. health care system when it comes to the prevention of substance abuse and addiction, specifi cally involving adolescents.

Read Full Article HTML DOI: 10.29328/journal.jatr.1001006 Citation

Review Article

Behavioral transformation through inner conflict resolution: A new Nursing Theory

The discipline of Hassidic Philosophy, which emanates from a particular movement in Orthodox Judaism called Hassidism, begins with the premise that all of creation is a dichotomous world of opposites with both sides in a perpetual conflict with one another.

Read Full Article HTML DOI: 10.29328/journal.cjncp.1001005 Citation


A flow perfusion bioreactor with controlled mechanical stimulation: Application in cartilage tissue engineering and beyond

To repair articular cartilage (AC) defects in osteoarthritic patients, one approach is to engineer threedimensional grafts with physicochemical properties similar to endogenous AC. Such grafts can be grown
in bioreactors that provide environmental conditions favoring chondrogenesis.

Read Full Article HTML DOI: 10.29328/journal.jsctt.1001011 Citation

Review Article

Discrepancy in Microglia and Peripheral Monocytic Cells - A scope in the Pathophysiology of Psychiatric maladies

Broad medleys of research have recognized the microglial activation in perilous psychiatric maladies such as schizophrenia, bipolar disorder, and major depressive disorder. There is a scenario of enlivening of peripheral monocytic cells along with the microglial interactions within the body

Read Full Article HTML DOI: 10.29328/journal.jnnd.1001011 Citation

Review Article

Metabolic Syndrome, Cardiovascular Disease and the Hair Growth Cycle: Addressing hair growth disruptions using Nourkrin® with Marilex® as a proteoglycan replacement therapy: A concise review

Alopecia is associated with an increased risk of coronary heart disease, and it appears that there is a relationship between the degree of hair loss and the risk of coronary heart disease, meaning, the greater the severity of alopecia, the greater the risk of coronary heart disease.

Read Full Article HTML DOI: 10.29328/journal.adr.1001004 Citation Views: 4819

Mini Review

Spinal muscular atrophy counteracted by Agrin biological NT-1654

Spinal muscular atrophy (SMA) is a genetic and gravely disease, portrayed by motor neuron (MN) death, thereby leading to progressive and accelerating muscle fragility, respiratory collapse, and, in the most severe cases, it even pave the way to death.

Read Full Article HTML DOI: 10.29328/journal.jnnd.1001009 Citation Views: 1337

Case Report

Predicament of classification: Multisystem small vessel vasculitis with cresentic Glomerulonephritis

The patient is a 28-year old Caucasian man with six month history of arthralgia and crampy abdominal pain who presented with acute dyspnea and cough for 6 months associated with migratory polyarthralgias involving his knees, ankles, wrists, and shoulders.

Read Full Article HTML DOI: 10.29328/journal.apcr.1001005 Citation