HSPC Articles

Articles Library

08/24/2021
Review Article

Flow cytometry potential applications in characterizing solid tumors main phenotype, heterogeneity and circulating cells

Louis WAECKEL, Guorong LI, Anne-Emmanuelle BERGER and Claude LAMBERT*

Abstract

Flow cytometry (FCM) is a unique technique that allows rapid quantitative measurement of multiple parameters on a large number of cells at the individual level. FCM is based on immunolabelling with fluorochrome-conjugated antibodies, leading to high sensitivity and precision ...

08/17/2021
Mini Review

Non-alcoholic fatty liver disease: Update on treatment options and translational implications of sleep disruption

Steve M D’Souza, Byung S Yoo, Kevin V Houston, Ankit J Patel, Parth J Parekh and David A Johnson*

Abstract

Non-alcoholic fatty liver disease (NAFLD) is a condition that is associated with cirrhosis and hepatocellular carcinoma, and is increasing in prevalence worldwide. Sleep disruptions are commonly seen in NAFLD, and the disease process is associated with sleep disorders, includ...

08/25/2021
Review Article

Victim of violent death: what is the role of alcoholemia?

Ivan Dieb Miziara* and Carmen Silvia Molleis Galego Miziara

Abstract

Introduction: The tendency to impulsive behaviors and/or violence is exacerbated after alcohol consumption. Still, the relation between alcohol/violent deaths reported in the literature is not accurate, and in general, alcohol is only seen as a trigger to aggressive actions. ...

08/17/2021
Research Article

Evaluation of the effectiveness of transcranial electrostimulation in treatment of neuropsychiatric disorders

Gagik Hakobyan*, Eduard Sekoyan, Karyna Shoman and Krasnopeeva Ekaterina

Abstract

Objectives: Evaluation of the effectiveness the method of transcranial electrostimulation in treatment of neuropsychiatric disorders with the use of a patches by the company “Aganyan”.

Materials and methods: The study was a double-blind, randomized, plac...

08/17/2021
Case Report

An incidental case report of Disc Battery Ingestion in a child with congenital hearing loss

Betsy Mathew* and Ananta Jois

Foreign body ingestion in children is a serious problem encountered among children. Approximately 80% of cases of foreign body ingestions occur in children between the ages of six months and three years [1]. Button battery ingestion occurs at an estimate rate of ten in one million people per year...

08/17/2021
Research Article

Immunocompromised patients with SARS-CoV-2 infection in intensive care units, outcome and mortality

Cynthia DENIS*, Hamid MERDJI, Mathieu BALDACINI, Maleka SCHENCK, Thierry ARTZNER, Yoann GRIMAUD, Thierry LAVIGNE, Ferhat MEZIANI, Vincent CASTELAIN, Raphaël CLERE-JEHL, Francis SCHNEIDER and Guillaume MOREL

Abstract

Background: The new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak severely hit Northeastern France from March to May 2020. The massive arrival of SARS-CoV-2 positive patients in the intensive care units (ICU) raised the question of how immunocompromise...

08/23/2021
Research Article

Evaluation of microbial contamination in a surgical department of a Romanian military emergency hospital - A case study

Bogdan-Ioan Coculescu* and Elena Claudia Coculescu

Abstract

Assessment of the microbial load of the operating environment during daily pre-, intra-, and post-operative procedures in a surgical department of a military emergency hospital in Bucharest showed the bacterial contamination of intra-operative air by increasing the number of ...

08/11/2021
Research Article

An algorithm to safely manage oral food challenge in an office-based setting for children with multiple food allergies

Nathalie Cottel, Aïcha Dieme, Véronique Orcel, Yannick Chantran, Mélisande Bourgoin-Heck and Jocelyne Just*

Abstract

Background: In France, from 30% to 35% of children suffer from multiple food allergies (MFA). The gold standard to diagnosis a food allergy is the oral food challenge (OFC) which is conducted in a hospital setting due to risk of anaphylaxis.

The aim of this study wa...

08/23/2021
Review Article

Application and utility of alternative methods in isolation of pure cells from forensic biological mixtures in modern-day: a review

Suneel Prajapati*, Poonam Rajmane, P Jayakrishna, Maya S Nair, Priyanka Kshirsagar and Mukul Meshram

Summary

Development of genetic profiles from the biological mixtures has remained challenging, although modern-day technologies may help forensic scientists to attain a reliable genetic profile in the identification of the accused.

In the case of rape, vaginal swab exhibits ...

08/10/2021
Review Article

Difference between conventional and modern methods for examination of fingerprints

Ambati Ramesh Babu*

Abstract

The impression of frictional ridges of the finger is known as fingerprints. Owing to this uniqueness, the fingerprints have long been used to identify a person since Ancient times. In any crime scene the presence of fingerprint makes the identification of the Culprit very easy....

08/10/2021
Mini Review

Strobilurins: New group of fungicides

Rasha E Selim* and Mohamed S Khalil

Abstract

Strobilurin is a group of natural products and their synthetic analogs have been widely used to control and prevent fungal diseases. Strobilurins were firstly isolated in 1977 from the mycelium of Strobilurus tenacellus, a saprobic Basidiomycete fungus causing wood-rotting on...

08/06/2021
Short Communication

MALDI-MSI method for the detection of large biomolecules in plant leaf tissue

Lilian ST Carmo, Daiane G Ribeiro, Eder A Barbosa, Luciano P Silva and Angela Mehta*

Abstract

In this study we describe a method for the detection of biomolecules (in the polypeptide m/z range) directly from the surface of plant leaves by using Mass Spectrometry Imaging. The plant-pathogen interaction between Arabidopsis thaliana and the bacterium Xanthomonas campestr...

08/10/2021
Review Article

An educational strategy for the implementation of a delirium assessment tool

Beatriz Bonaga*, Elena Ruiz-Escribano Taravilla, Carmen Carrilero-López, María Dolores Castillo-Lag, Leanne M Boehm, Ángela Prado Mira, María Joaquina Piqueras Diaz and E Wesley Ely

Abstract

Background: Delirium is an acute syndrome of organ dysfunction with long-term consequences which commonly occurs in the Intensive Care Unit (ICU). The incidence of delirium ranges from 30% - 50% in low severity ICU patients and up to 80% in mechanically ventilated patients. T...

08/20/2021
Research Article

Factors influencing referral delay of cancer patients to an oncology unit in the Southern Region of Saudi Arabia

Ali M Al Zahrani*, Hatim M Ali, Shaza A Ahmed, Ahmed M Abdelakher, Asma A Al Zahrani and Hatoon Bakhribah

Abstract

Introduction: Cancer treatment and prognosis depend heavily on early detection. Survival in the early stages is excellent for almost all types of cancer. Unfortunately, in Saudi Arabia, a large number of cancer patients present with advanced disease, resulting in a poor progn...

08/16/2021
Case Report

Leiomyosarcoma in pregnancy: Incidental fi nding during routine caesarean section

Toon Wen Tang* and Phoon Wai Leng Jessie

Abstract

Uterine leiomyosarcoma (LMS) is uncommon tumour arising from the female reproductive tract. Incidence of LMS in pregnancy is extremely rare, with only 10 cases reported thus far in medical literature.

We present a case of myomectomy performed during elective caesare...

08/10/2021
Research Article

A rare presentation of orbital dermoid: A case study

Sheetal V Girimallanavar*, Seema Channabasappa, Balasubrahmanyam Aluri, Divya Rose Cyriac and Aiswarya Ann Jose

Summary

Introduction: A dermoid cyst is a developmental choristoma lined with epithelium and filled with keratinized material arising from ectodermal rests pinched off at suture lines. These are the most common orbital tumors in childhood. They are categorized into superficial and dee...

08/05/2021
Research Article

A comparative study of post-operative astigmatism in superior versus superotemporal scleral incisions in manual small incision cataract surgery in a tertiary care hospital

Soumyadeep Hazra* and Tapes Kanti Saha

Abstract

Background: In developing countries, manual small incision cataract surgery is a better alternative and less expensive in comparison to phacoemulsification and thus the incision is an important factor causing high rates of postoperative astigmatism resulting into poor visual ou...

08/09/2021
Review Article

SARS-CoV-2 Infection, COVID-19, and long covid: Saga of erratic immune response, waning immunity, and immune system failure

Vinod Nikhra*

Abstract

Introduction - evolution of SARS-CoV-2 variants: With the unrestrained pandemic for over last one-and-half year, SARS-CoV-2 seems to have adapted to its habitat, the human host, through mutations that facilitate its replication and transmission. The G variant incorporating D6...

08/05/2021
Case Report

“Fatty Lungs”: An uncommon case of Autoimmune Pulmonary Alveolar Proteinosis

Arnaldo A Nieves-Ortiz*, Kyomara Hernandez-Moya, Juan Garcia-Puebla, Kimberly Padilla-Rodriguez, Neshma Roman-Velez, Giovanni Veloz-Irizarry, Keren Mendez-Ramirez, Hector Collazo-Santiago, Jose Adorno-Fontanez and Ricardo Fernandez-Gonzalez

Pulmonary Alveolar Proteinosis (PAP) is a rare lung disease characterized by excessive accumulation of surfactant lipids and proteins in alveoli and terminal airways. It is caused by impaired GM-CSF signaling [1]

08/04/2021
Case Report

“Vanishing” breast implant – when a breast prosthesis is moving into the pleural cavity

Thomas Grieser*, Daniel Popp, Stephan Raab and Thomas Berghaus

A 57-year-old woman has been referred to our hospital in April 2020 because of suffering necrotizing pneumonia in the right upper lung lobe secondary to preceding pulmonary embolism half a year ago (Figure 1A,B).

08/04/2021
Case Report

Non-smoking woman with adenocarcinoma of the lung, IV stage with ROS1 mutation and acquired thrombophilia

Immanuels Taivans*, Natalja Senterjakova, Viktors Kozirovskis, Gunta Strazda, Jurijs Nazarovs and Valentina Gordjusina

Abstract

Despite the fact, that lung cancer is more common among older smoking men, however it may also develop among young women without a smoking anamnesis. We report here a history of a non-smoking woman, 40 years old, with a diagnosis of lung adenocarcinoma at IV stage. Despite th...

07/30/2021
Case Report

Pulmonary mucormycosis in post-pulmonary tuberculosis as an emerging risk factor: A rare case report

Divya Khanduja* and Naveen Pandhi

Abstract

Pulmonary mucormycosis is an uncommon pulmonary fungal disease, which is commonly seen in immunocompromised individuals. It is caused by fungi of class Zygomycetes. It constitutes the third most common invasive fungal infection following aspergillosis and candidiasis. Risk fa...

07/30/2021
Case Report

A Case series on Asthma-COPD overlap (ACO) is independent from other chronic obstructive diseases (COPD and Asthma)

Divya Khanduja* and Naveen Pandhi

Abstract

As we know that, Asthma and chronic obstructive pulmonary diseases are well characterized diseases, they can co-exist as asthma-COPD overlap (ACO). The co-existence of asthma-chronic obstructive pulmonary disease overlap (ACO) in chronic obstructive pulmonary disease (COPD) p...

08/02/2021
Research Article

Associations of adverse social determinants of health with missed well-child visits and the role of caregiver social support

William Roberts, Eun Ji Kim*, Johanna Martinez and Omolara Thomas Uwemedimo

Abstract

Objective: To examine the association between adverse social determinants of health (SDH) and missed well-child visits and the interaction with the level of caregiver social support.

Methods: This is a secondary data analysis of data collected from a SDH screening p...

07/30/2021
Review Article

A retrospective review of the factors that negatively influenced the eradication of polio in South-South, Nigeria

Peters Grace E*, Assi Victor, Oko Nnabuike E and Peters Etete J

Abstract

Background: The endemic nature of poliomyelitis in Nigeria was a source of concern to many given the global efforts aimed at eradicating the scourge. In this study, the factors that influenced the eradication of this malady in South-South Nigeria (Akwa Ibom and Cross River St...

07/28/2021
Review Article

Cannabinoids as a yield modifier in physical activit: A systematic review characters

Leonardo Tibiriçá Corrêa, Juliana Weckx Peña Muñoz6, Beatriz do Prado Pacca Faria, Jeferson Santana, Leandro Yanase Rocha, EstherLopes Ricci, Lorena de Paula Pantaleon, Leonardo Ribeiro de Paula, Guilherme Mendes Ribeiro, Vinicius Barroso Hirota and André Rinaldi Fukushima*

Abstract

Marijuana is considered illicit in much of the world, and is classified as a drug for recreational use, in recent decades the medicinal use of Cannabis sativa L. has grown and diversified, being considered the only therapeutic alternative in the control of serious and incurab...

07/28/2021
Review Article

Current challenges in plant breeding to achieve zero hunger and overcome biotic and abiotic stresses induced by the global climate changes: A review

Gniech Karasawa Marines Marli*

Abstract

According Sustainable Development goals until 2030 we should have zero hunger and undernourished people in the world. But to achieve this goal plant breeders must improve plants in order to produce at least the double than is produced now. This is not a easy pathway because w...

07/27/2021
Review Article

The continued relevance of Deep Brain Stimulation for chronic pain

Sarah Marie Farrell and Tipu Aziz*

Abstract

For the millions of patients experiencing chronic pain despite pharmacotherapy, deep brain stimulation (DBS) provides a beacon of hope. Over the past decade the field has shifted away from DBS towards other forms of neuromodulation, particularly spinal cord stimulation (SCS)....

07/27/2021
Research Article

Five-year follow up on the single level corpectomy

Frank Phillip Castro*

Single-level Anterior Cervical Decompression and Fusion (ACDF) was initially performed using Iliac Crest Bone Graft (ICBG) [1].

07/20/2021
Research Article

The SARS CoV-2 spike domain, RGD and integrin binding effect-relationship for vaccine design strategy

Luisetto M*, Tarro G, Khaled Edbey, Almukthar N, Cabianca L, Mashori GR, Ahnaf Ilman, Yesvi AR and Latyschev OY

Abstract

Related the need to search new strategy in vaccine design in order to reduce also some rare effect like trombosys for some registered products it is interesting the role played by the SPIKE RGD domain.

The binding with molecules like Fibronectin is a process that mu...

07/20/2021
Research Article

Sleep quality and associated factors among patients with chronic illness at South Wollo Zone Public Hospitals, Northeast Ethiopia

Afework Edmealem*, Sewunet Ademe and Atsedemariam Andualem

Abstract

Background: Pathological and nighttime sleep deprivations have substantial adverse effects on regulation of weight, sugar and blood pressure because of endothelial dysfunction, sympathetic nervous system stimulation, regulation and activation of systemic inflammation. Thus, thi...

07/27/2021
Clinical Image

Malignancy induced haemophagocytosis by erthroid cells and its transformation into a multinucleated giant cells – A unique clinical image

Prachi*, Gaurav Sharma and Suparno Chakrabarti

Haemophagocytosis is a dysregulated immune condition characterised by both inflammation and uncontrolled activation of macrophages and T-cells, which causes aberrant cytokine release, leading to cytokine storm [1] it can be primary or secondary, depending upon the etiology.

07/21/2021
Clinical Image

Atypical cutaneous relapse of multiple myeloma

Jean-Baptiste Rieu*, Francois Vergez, Jill Corre, Aurore Perrot and Pierre-Luc Mouchel

A 66-year-old patient, diagnosed κ light chains MM with t(11;14), presented before second cycle with bendamustine-dexamethasone.

07/31/2021
Letter to the Editor

Myxedema coma in COVID-19

Yuichi Takashi* and Daiji Kawanami*

Abstract

SARS-CoV-2 infection is associated with thyroid disorders. It has been reported that myxedema coma (MC) can be complicated with COVID-19. COVID-19-related thyroid disorders consist of a broad spectrum of thyroid dysfunction, from thyrotoxicosis to decompensated hypothyroidism...

07/28/2021
Case Report

Blunt abdominal trauma with duodenal dissection: A case report

Basile Essola*, Jean Baptiste Boumsong Batamag, Jean Paul Engbang, Dominique Djomo, Esdras Ngaroua, Jacques Landenne and Jean Gustave Tsiagadigui

Abstract

We describe a new case of duodenal wound with complete transection in a 22-year-old patient following a motorcycle accident. He presented to the emergency room of the rural Regional Hospital of Edéa in Cameroon with a clinical picture of acute abdomen and post-trauma h...

07/23/2021
Research Article

Practice patterns and outcomes of repository corticotropin injection (Acthar® Gel) use in childhood nephrotic syndrome: A study of the North American Pediatric Renal Trials and collaborative studies and the Pediatric Nephrology Research Consortium

Mohammed K Faizan*, Courtney McCracken, Kenneth Lieberman, Traci Leong and Mark R Benfield

Summary

Objective: We set up a U.S. registry to examine prescription patterns and patient outcomes of repository corticotropin injection (Acthar® Gel) for childhood nephrotic syndrome.

Methods: 18 participating U.S. pediatric centers performed retrospective review and pr...

07/21/2021
Research Article

Multifrecuency bioimpedance phase angle as a tool to predict maturation failure of native fistulae for hemodialysis

José Lucas Daza Lopez*, John F Galindo, Mónica R Villaquiran, Emilio D Valenzuela, Andres Cardenas, Luis Jose Daza6, Maria Camila Correcha, Jonathan de Jong, Yaroslad De La Cruz Prieto, Gerardo Gutierrez and Luis Puello

Summary

Background and objectives: An arteriovenous fistula is considered to be an ideal vascular access for patients receiving hemodialysis, its main limitation is its high failure rate to achieve maturation and long-term functionality loss. Multiple strategies have attempted to iden...

07/20/2021
Research Article

Usefulness of foot-to-foot bioimpedance analysis for assessing volume status in chronic hemodialysis patients at the Aristide Le Dantec University Hospital (Senegal)

Niakhaleen Keita*, Maria Faye, Sidy Mouhamed Seck, Boucar Ndong, Moustapha Faye, Ahmed Tall Lemrabott, Bacary Ba, Seynabou Diagne1, Mansour Mbengue, Ameth Dieng, Mamadou Aw Ba, Abdou Sy, Modou Ndongo, Babacar Ndiaye and Elhadji Fary Ka

Summary

Introduction: Determination of dry weight is one of the daily goals to achieve in hemodialysis. The aim of this study was to validate the use of bioelectrical impedance analysis (BIA) in estimation of dry weight in a population of Senegalese chronic hemodialysis patients.

...

07/16/2021
Research Article

Management outcome of intestinal obstruction done by integrated emergency surgical officers and its associated factors in selected district hospitals of South Wollo Zone, North East Ethiopia in 2019 G.C

Sewunet Ademe*, Afework Edmealem, Belachew Tegegne and Zemen Mengesha

Abstract

Background: Intestinal obstruction (IO) is defined as a partial or complete blockage of the bowel that results in the failure of intestinal contents to pass through. It is a common cause of emergency surgical problems. IO has been the leading cause of acute abdomen in several...

07/16/2021
Case Report

Gallstone Ileus with associated perforated small bowel diverticulitis

Shreeja Mehrotra*, Yang Huang, Ronan Knittel and Palan Thirunavukkarasu

Gallstone ileus is a rare complication of cholelithiasis and a type of mechanical obstruction involving impaction of a gallstone within the intestinal tract [1,2]. This entity occurs in 0.15% - 1.5% of cholelithiasis cases and < 0.1% of ileus cases overall [1]. Gallstone ileus is more common i...

07/20/2021
Clinical Image

COVID-19 Associated acute limb ischemia

Yogendra Mishra*, Satish Kumar and Meghna K

A 78-year-old man, known case of, diabetes mellitus, and hypertension presented with fever, dry cough and dyspnea of five-day duration.

07/16/2021
Research Article

Comparative efficacy of inspiratory, expiratory and combined respiratory muscle training on the pulmonary functions and chest expansion in acute stroke survivors

Adeogun Abiodun A* and Umar Dolapo K

Abstract

Background: Respiratory muscle strength can be reduced in patients diagnosed with stroke, which reasonably justifies the use of respiratory muscle training in this population. This study determines the comparative efficacy of inspiratory, expiratory, and combined respiratory ...

07/14/2021
Case Report

Acute Kidney Injury due to spontaneous Atheroembolic disease, superimposed on diabetic nephropathy, with no recent vascular or cardiac intervention, presented as Rapidly Progressive Glomerulonephritis (RPGN)

Anas Diab*, Parravani Anthony, Hollie Berryman and Kareem Diab

Atheroembolic disease (AED), or Cholesterol Crystals Embolism, is a systemic disease presented as a complication of severe atherosclerosis [1], where older age, male sex, diabetes hypercholesterolemia, smoking and hypertension [2], are the main risk factors for the development of  Atheroscle...

07/14/2021
Review Article

Hypertension: A global health crisis

Pius AL Berek*, Dewi Irawati and Akhir Yani S Hamid

Abstract

Objective: This study discusses strategies to overcome hypertension patient compliance to manage self-care. The purpose of the study is to provide a summary of the importance of attention to managing hypertension.

Method: a review of literature relevant to hypertens...

07/15/2021
Review Article

Multimodal treatment strategies in Huntington’s disease

Rajib Dutta*

Abstract

Huntington’s disease (HD) is an incurable neurodegenerative disease that causes involuntary movements, emotional lability, and cognitive dysfunction. HD symptoms usually develop between ages 30 and 50, but can appear as early as 2 or as late as 80 years. Currently no ne...

07/12/2021
Review Article

Revisiting childhood pneumonia in low-recourse setting hospitals

Karimeldin MA Salih*

Abstract

Introduction: Pneumonia, defined as infection of lung parenchyma, is associated with severe complications especially in the very young and old patients. It is the world’s leading cause of childhood mortality. The World Health Organization (WHO) classification and guidel...

06/17/2021
Research Article

Predictors of mortality in neonatal sepsis in a resource-limited setting

Adonis Muganza Nyenga, Olivier Mukuku, André Kabamba Mutombo, Charles Wembonyama Mpoy, Oscar Numbi Luboya and Stanis Okitotsho Wembonyama*

Abstract

Introduction: Sepsis remains a major cause of death in neonatal period. Although significant advances in diagnosis, therapeutic and prevention strategies have been noted, sepsis remains a common concern in clinical practice especially in low-resource countries. The aim of thi...

07/09/2021
Research Article

AsdamarinTM relieves functional dyspepsia in healthy adults in only 7 days: A randomized, double-blind, placebo-controlled pilot study

David Daguet*, Sudeep Heggar Venkataramana, Justin V Thomas and Shyam Prasad Kodimule

Abstract

Functional dyspepsia (FD) is a prevalent global health concern increasing with years. Inspired by the Traditional Chinese Medicine (TCM) liver-stomach disharmony syndrome in order to find a quick natural alternative treatment, a Ferula asafoetida-Silybum marianum (Asdamarin&t...

07/15/2021
Case Report

Facial-onset sensory-motor neuronopathy, a rare variant of Huntington’s disease or chance association?

Raul Juntas-Morales, Elisa De La Cruz, Florence Esselin, Nicolas Pageot, Guillaume Taieb and William Camu*

Abstract

Objectives: To describe a patient with facial-onset sensory-motor neuronopathy (FOSMN) that later developed Huntington’s disease (HD).

Case report: A 62-year-old woman complained of progressive dysphagia 8 years before referral. At initial evaluation, there wa...

07/07/2021
Research Article

Epidemiological profile of the homeless population assisted by voluntary initiative and the social impact on access to healthcare: an investigative study in Curitiba, Brazil

Rafael Senff Gomes, Luiza Cardoso de Lima Passoni, Ricardo Sirigatti and Francelise Bridi Cavassin*

Summary

Objective: The study aimed to describe the epidemiological profile of the homeless population and report the social impact on healthcare services provided by a voluntary initiative during one-year of follow-up.

Method: This is an investigational study, carried out in...

07/09/2021
Research Article

Open heart surgery in Nigerian children the need for international and regional collaboration: The Bayelsa and Enugu experience

Ujunwa FA, Ujuanbi AS, Chinawa JM*, Allagoa DO and Onwubere B

Abstract

Background: Children with congenital heart diseases (CHD) often require palliative or definitive surgical heart interventions to restore cardiopulmonary function. Lack of early cardiac intervention contributes to large numbers of potentially preventable deaths and sufferings ...

07/06/2021
Research Article

Nurses knowledge and practice in assessment and management of neonatal pain at Governmental Hospitals in Gaza Strip: A cross sectional study

Yunis KS Qasim*, Hamza Abdeljawad and Ali H Abusafia

Abstract

Objective: The study aimed to investigate neonatal nurses' knowledge and practices related to pain assessment and management that may contribute to improve the quality of pain management by nurses at Neonatal Intensive Care Units (NICUs) of governmental hospitals in Gaza ...

06/29/2021
Research Article

Comparative analysis of cesarean section using the Robsons Ten-Group Classification System (RTCGS) in private and public hospitals, Addis Ababa, Ethiopia

Endalkachew Mekonnen Assefa, Adem Janbo and Yirgu Ghiwot

Abstract

Objectives: We analyzed the indications of cesarean section (CS) using Robson Ten-Group.

Classification Systems (RTGCS) and comparison between private and public health facilities in Addis Abeba hospitals, Ethiopia, 2017.

Methods: Facility-based retrospect...

07/05/2021
Research Article

Novel Coronavirus Disease (COVID-19): An extensive study on evolution, global health, drug targets and vaccines

Abdul Ashik Khan, Tanmoy Dutta, Palas Mondal, Manab Mandal, Swapan Kumar Chowdhury, Minhajuddin Ahmed, Nabajyoti Baildya, Sourav Mazumdar and Narendra Nath Ghosh*

Abstract

The Coronavirus disease-2019 (COVID-19), has become a worldwide pandemic and the scientific communities are struggling to find out the ultimate treatment strategies against this lethal virus, Severe Acute Respiratory Syndrome Coronavirus–2 (SARS-CoV-2). Presently, there...

07/02/2021
Review Article

OPEN and CLOSED state of SPIKE SARS-COV-2: relationship with some integrin binding. A biological molecular approach to better understand the coagulant effect

Luisetto M, Khaled Edbey, Mashori GR, Ahnaf Ilman, Yesvi AR and Latyschev OY

Abstract

Related the physio-pathological process of COVID-19 disease it is interesting to focus to the aspect.

Played by interaction of Sars-Cov-2 protein with integrins of human epithelial pulmonary cell.

A bio molecular approach help in to deeply verify the invol...

07/06/2021
Review Article

Role of neuron specific enolase as a biomarker in Parkinson’s disease

Rajib Dutta*

Abstract

Parkinson’s disease (PD) is thought to be the most common neurodegenerative disease with movement disorder. The key motor symptoms are rigidity, tremor, akinesis/hypokinesia/bradykinesia, and postural instability. However, in our day-to-day clinical practice we tend to ...

06/29/2021
Research Article

Endovascular management of tandem occlusions in stroke: Treatment strategies in a real-world scenario

Juan J Cirio*, Celina Ciardi, Matias Lopez, Esteban V Scrivano, Javier Lundquist, Ivan Lylyk, Nicolas Perez and Pedro Lylyk

The association between intracranial large vessel occlusion (LVO) and concurrent steno-occlusive lesion of an ipsilateral extracranial internal carotid artery (ICA) is considered a tandem occlusion (TO) [1].

06/30/2021
Case Report

Intravascular leiomyoma misdiagnosed as deep vein thrombosis: A case report

Yiheng Zhang, Feng Wen*, Zhen Liu and Zaiming Lu

Abstract

Background: Leiomyoma itself is not a rare disease, but it is rarely found intravascularly.

Case presentation: A 54-year old female sought medical help after noticing her leg being swelling. A diagnosis of deep vein thrombosis (DVT) was made and antithrombotic treat...

03/18/2021
Research Article

Efficacy of ozonized sunflower oil as treatment of canine generalized demodicosis

Zullyt Zamora Rodriguez*, Marielys Lemus, Eduardo Fleitas González and Oscar Ernesto Ledea Lozano

Abstract

Background: The acaricidal action of Ozonized sunflower oil (OSO) has demonstrated in different clinical cases of different animal species, such as psoroptic rabbits and pig sarcoptic scabies and recently in demodesic goat.

Objectives: This study evaluated the effec...

06/25/2021
Case Report

Organizing pneumonia as the initial presentation in rheumatoid arthritis – A case report

Harveen Kaur, Dilbag Singh and Naveen Pandhi

Abstract

Organizing pneumonia (OP), can be seen in association with lung injury, infection, drug intoxication, and connective tissue diseases. Patients of rheumatoid arthritis (RA) are prone to develop interstitial lung disease (ILD), but the pulmonary involvement usually occurs sever...

06/14/2021
Review Article

Pigeonpea sterility mosaic virus a green plague-Current status of available drug and new potential targets

Nisha Singh*, Bhawna Narula, Megha Ujinwal and Sapna Langyan

Abstract

Pigeonpea is one of the important legume crops with high protein content and nutritional traits. It has enormous potency for its widespread adoption by farming communities. It is affected by various kinds of biotic and abiotic stresses. In the context, of biotic stresses Ster...

06/30/2021
Letter to the Editor

Neo communicable disease rather than ‘non’ communicable disease for the acronym “NCD”

APR Aluwihare*

It is with interest and pleasure that I see notices of meetings and symposia, and articles, devoted to the theme Noncommunicable disease. I still live in the economic and geographical ‘South’ but the concern arises from the continued use of terminology that dulls the senses to the urg...

06/28/2021
Research Article

Institutional capacity of health care institutes for diagnosis and management of common genetic diseases - A study from a north coastal district of Andhra Pradesh

Koteswara Rao Pagolu* and T Raghava Rao

Abstract

Background: In India, the genetic disease is a disregarded service element in the community health- protection system. This study aims to gauge the accessibility of services for treating genetic disorders and also to evaluate the practices on deterrence and management service...

06/24/2021
Research Article

Simulating the dispersion of poisonous organic chemical compounds in wastewater treatment process through the active sludge method using the TOXChem model

Seyyed Roohollah Masoomi, Mostafa Azizi, Reza Aghlmand, Mohammad Gheibi* and Zahra Kian

Abstract

Naturally, microorganisms decompose the organic material existing in nature, both in the presence or absence of oxygen. The majority of materials such as poisonous chemical compounds, heavy metals, would prevent the treatment process from taking place, lead to the entry of th...

06/09/2021
Review Article

Assessment and sensitive analysis of biological water risks in water resources with application of classical mass transfer computations

Farhad Mahmoudi Jalali, Mohammad Gheibi*, Reza Aghlmand, Amir Takhtravan and Zahra Kian

Abstract

Due to the urgent need for water in all parts of industrial or developing societies, water supply, and transmission facilities are suitable targets for biological risks. Given that even a short interruption in water supply and water supply operations has a great impact on dai...

06/25/2021
Research Article

On Friedman equation, quadratic laws and the geometry of our universe

S Kalimuthu*

Abstract

Einstein’s special and general relativity revolutionized physics. The predictions of general relativity are Strong Lensing, Weak Lensing, Microlensing, Black Holes, Relativistic Jets, A Gravitational Vortex, Gravitational Waves, The Sun Delaying Radio Signals, Proof fro...

06/18/2021
Research Article

Impact of COVID-19 outbreak on urology practice in India

Mahendra Singh*, Himanshu Pandey, Prateek Gupta, Gautam Ram Choudhary, Vipin Tyagi, Vijay Kumar Sarma Madduri and Nikita Shrivastava

Abstract

Background: The rapid spread of “Coronavirus Disease 2019’ (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus-type 2 (SARS-CoV-2) significantly impacted health care facilities all across the globe. To assess impact on urology practice in our countr...

06/05/2021
Research Article

Artemisia Naphta: A novel oil extract for sensitive and acne prone skin

Kan Tao, Lili Guo, Jose Fernandez, Corey Webb, Junfeng Liu, Xincheng Hu, Dan Yang and Edwardo Perez*

Abstract

Background: The plant Artemisia annua has been used in traditional Chinese medicine for many years. Rich in bioactive molecules, the A. annua plant is used to extract the anti-malaria compound artemisinin (< 1%), which results in most of the plant being unutilized. One byp...

06/18/2021
Research Article

Cystic fibrosis, the key link with airborne alpha emitting nanoparticulates

Florent Pirot*

Abstract

Cystic fibrosis is explained in this paper that suggests tackling the disease by elimination of the most significant sources of contamination.

06/11/2021
Research Article

Meclizine prescriptions in the Emergency Department and return visits in the elderly population

Samantha McGlone, Edward Castillo, Ronald Dunlay and Alicia Minns*

Abstract

Background: Meclizine is a commonly prescribed medication for patients discharged from the Emergency Department (ED) with a diagnosis of peripheral vertigo, however it is on the Beers list of medications to avoid in elderly patients.

Objectives: This study aims to d...

06/15/2021
Review Article

Pulmonary Involvement in COVID-19 and ‘Long Covid’: The Morbidity, Complications and Sequelae

Vinod Nikhra*

Abstract

Introduction: the perennial pandemic: There are serious challenges posed by the SARS-CoV-2 virus and COVID-19 as the disease. With the persistence of the pandemic over one and half year, it is being feared that the COVID-19 may have become the new reality associated with huma...

06/11/2021
Research Article

Factors associated with Female Genital Mutilation among daughters of reproductive aged women at Academic Charity Teaching Hospital (ACTH)

Danyah Shiddo* and Hilmi Nour

Abstract

Introduction: It is estimated that more than 200 million girls and women alive today have undergone female genital mutilation. Female genital mutilation still remains to be a serious problem for large proportion of women in most sub-Saharan Africa countries including Sudan, w...

06/09/2021
Research Article

Pathogen identification and control of sooty spot caused by Cladosporium ramotenellum, appearing on fresh easy peeler mandarins from Perú

Celia Murciano*, Jeniffer J Oliver-Chirito and Benito Orihuel-Iranzo

Abstract

During the 2018 season, superficial dry and firm black spots, where sometimes an aerial mycelium developed, appeared on the rind of easy peeler mandarins causing high economic losses in fresh citrus exports from Perú. In this work, we have identified the causal agent, ...

06/07/2021
Research Article

Self-care practice and associated factors among type 2 adult diabetic patients on follow up clinic of Dessie referral hospital, Northeast Ethiopia

Sisay Gedamu Addis*, Sewunet Ademe Kassahun, Samuel Anteneh Ayele, Abebe Dires Nega and Kirubel Dagnaw Tegegne

Abstract

Background: Diabetes mellitus is a common health problem in the world and Africa including Ethiopia. Its complication is the major cause of morbidity and mortality of people due to improper self-care practice.

Objective: To assess self-care practices and associated ...

06/04/2021
Research Article

Demographic profile & correlation between retinal exudates and hematological parameters in leukemic patients

FM Monjur Hasan and Richmond Ronald Gomes*

Abstract

Background: Leukemia is frequently associated with fundoscopic abnormalities. However, no organized effort has been made for analyzing leukemic retinopathy in our country. This study was done to observe the demographic profile and correlation between fundoscopic findings of r...

06/09/2021
Review Article

Differential diagnosis of POLG related disorders: What to keep in mind when multiorgan system is involved?

Rajib Dutta*

Abstract

Mitochondrial and lysosomal dysfunction accounts for a large group of inherited metabolic disorders most of which are due to a dysfunctional mitochondrial respiratory chain (MRC) leading to deficient energy production and defects in phagocytosis in endosomal-lysosomal pathway...

06/03/2021
Review Article

Endocannabinoidome and its role in neurological disorders-A comprehensive update of existing literature

Rajib Dutta*

Abstract

Medical benefits of cannabis and related compounds is widely known. Discovery of psychotropic plant cannabinoid Δ9-tetrahydrocannabinol have urged researchers to study more about the cannabinoid system and related therapeutics in the field of neurology and medicine. Whe...

05/31/2021
Short Communication

Finite element method in equine orthopedics

Anderson Fernando de Souza* and André Luis do Valle De Zoppa

The finite element method (FEM) is an engineering resource used to predict the stresses in structures that have complex geometries, specific material properties and are subject to complex loading patterns, being widely used in medical and biological research. It has the advantage of being a nonin...

05/26/2021
Case Report

Minimal treatment options with one-piece implants

Jimoh Olubanwo Agbaje, El Moheb Mohamad and Henri Diederich*

Aim

The aim of this publication is to present case reports to show what is possible with pterygoid implants for the rehabilitation of edentulous space in the jaw (maxilla) while avoiding sinus lifts and bone grafting procedures. In addition, the added value of one-piece implants for s...

05/26/2021
Research Article

The epidemiology, evaluation, and assessment of lateral ankle sprains in athletes

G Javier Cavazos Jr.* and Lawrence B Harkless

Summary

Approximately 30,000 ankle injuries occur every day in the United States. With the incidence estimated at more than 3 million a year and at a rate of 2.15/1,000 in the U.S. alone, medical specialists and other healthcare providers caring for the foot and ankle must take notice...

05/24/2021
Research Article

Working process of steam turbine and establishment of start-up model

Chao Dong and Yongjian Sun*

Abstract

In the research of steam turbine rotor, start-up optimization is a very key research problem. A series of start-up optimization research can greatly improve the start-up efficiency of steam turbine and the safety performance of the unit. The start-up optimization of steam tur...

05/22/2021
Research Article

Magnetohydrodynamic (MHD) stability of wendelstein7-X reactor with resistive wall (RWMs)

Ali Pazirandeh* and Mehrnaz Sadat Shariati

Abstract

Plasma stability is the biggest challenge facing the nuclear fusion industry. One of the best methods of stability study is magnetohydrodynamic (MHD) equations, which has two linear and nonlinear states. Usually linear stability analysis is used to describe the MHD state, whi...

05/26/2021
Research Article

Ion transporters and their molecular regulation mechanism in plants

Walid Saibi and Faiçal Brini*

Abstract

With the global population predicted to grow by at least 25% by 2050, the need for sustainable production of nutritious foods is important for human and environmental health. Recent progress demonstrate that membrane transporters can be used to improve yields of staple crops,...

05/20/2021
Case Report

A rare cause of neonatal diarrhoea: Microvillositary inclusion disease: about a case report

M Akhrif*, M Sabib, L Rouas, T Meskini and N Mouane

Abstract

Microvillositary inclusion disease also known as microvillositary atrophy is a rare congenital enteropathy containing a border abnormality in the brushes of enterocytes, manifesting as severe rebellious diarrhea in newborns and infants. It was first described in 1978 by David...

05/17/2021
Case Report

Rapidly involuting congenital hemangioma associated with Kasabach-Merritt Syndrome

Rosalia Ballona*, Jean Zevallos and Jeanette Núñez

Abstract

Background: Rapidly involuting congenital hemangioma (RICH) is a rare vascular tumor that is present at birth and involutes during the first year of life. Kasabach-Merritt syndrome (KMS) is a complication of some vascular tumors such as kaposiform hemangioendothelioma and tuf...

05/19/2021
Review Article

A review article on artificial intelligence

Nagendraswamy C* and Amogh Salis

Abstract

Artificial intelligence (AI) is the emulation of human intelligence in computers that have been trained to think and behave like humans. The word may also refer to any computer that exhibits human-like characteristics like learning and problem-solving. Artificial intelligence...

05/13/2021
Research Article

Clinical picture of pulmonary plague observed in the paediatric wards of antananarivo

Rivo Lova Herilanto Rakotomalala*, Lovasoa Randriamanga, Mihary Soa Karol, Mioramalala Sedera Aurélien and Annick Lalaina Robinson

Abstract

Introduction: In Madagascar, plague is a highly contagious acute endemic infectious disease. The diagnosis of the most severe form of pneumonic plague remains difficult in children, hence the objectives of the present study; which is to identify the clinical signs of this cli...

05/12/2021
Review Article

Orofacial manifestations of COVID-19

Hariharan Ramakrishnan* and Maniamuthu Ragupathi

Abstract

Oral cavity is the gateway of the human body, and also provides vital clues of our systemic health. Here in this COVID-19 pandemic, oral manifestations such as dysgeusia, ulcers, xerostomia are noticed and are an an important predictors of this viral disease. This short revie...

05/13/2021
Research Article

Medicinal plant Potentilla fulgens and its effect in vitro against Fasciola gigantica

Pradeep Kumar*

Abstract

Fascioliasis is a one of the most important serious parasitic zoonotic disease which caused by trematode giant liver fluke Fasciola hepatica and F. gigantica among cattle’s and humans. The infection of Fasciola can be control by the use of phytochemicals as anthelmintic...

05/12/2021
Letter to the Editor

Follicular psoriasis: a poorly known presentation

Khallaayoune M*, Mansouri S, Sialiti S and Hassam B

Abstract

Follicular psoriasis is an uncommon diagnosis and probably the least well-known subtype of psoriasis. Hence, we report the clinical and histological findings of follicular psoriasis in one patient to raise awareness of this rare entity.

05/11/2021
Research Article

Factors associated with mortality after decompressive craniectomy in large basal ganglia bleeds

Amit Kumar Thotakura*, Nageswara Rao Marabathina, Rama Krishnareddy Mareddy and Sivaramanjaneyulu Yeddanapudi

Abstract

Aim: To assess the efficacy of decompressive craniectomy in patients with large basal ganglia (BG) bleed. To establish predictive criteria of mortality after surgery in patients with BG bleed.

Materials: This prospective study includes all patients of large spontane...

05/07/2021
Research Article

Suicide in teenagers during the COVID-19 pandemic in Cuba: actions for its prevention

Claudia Elvira Casamayor Leiza, Julio César Pérez Yero, Maydell Pérez Inerárity* and Brayan Chávez Miguel

Abstract

Introduction: Suicidal behavior in teenagers constitutes a health problem that, given the necessary measures of social isolation taken by the global emergency of the COVID-19 pandemic, must generate timely actions for its prevention and control from the public health services...

05/07/2021
Research Article

Mestranol moieties clicked to Zn(II)phthalocyanine for controllable photosensitized oxidation of cholesterol

Vanya Mantareva*, Meliha Syuleyman, Adriana Slavova-Kazakova, Ivan Angelov and Mahmut Durmus

Abstract

Four mestranol moieties were chemically linked to Zn(II) phthalocyanine (4) by cycloaddition “Click” reaction using a tetra-azidoethoxy substituted Zn(II)-phthalocyanine (3). The alkyl-azido coupling reaction was realized between azido groups of 3 and alkyl group of...

05/05/2021
Research Article

In vitro beneficial effects of a flax extract on papillary fibroblasts define it as an anti-aging candidate

PAGEON Hervé*, ZUCCHI Hélène, RICOIS Sylvie, BASTIEN Philippe and ASSELINEAU Daniel

Abstract

Objective: During aging, skin undergoes structural, cellular and molecular changes, which not only alter skin mechanical properties but also biological and physiological functions. Structurally the epidermis becomes thinner, the dermal epidermal junction flattens and the extr...

05/05/2021
Research Article

Impact of a multidisciplinary pre-dialysis program on renal treatment modalities choice

Luis Miguel Castro Fonseca dos Santos Oliveira*, Rui Arlindo dos Santos Alves de Castro and Teresa Margarida Ribeiro Pinto Morgado

In Portugal, around 2500 patients with end-stage chronic kidney disease (CKD stage 5) start a renal replacement therapy (RRT) for the first time each year [1]. They have four main treatment options: kidney transplantation (TX); haemodialysis (HD); peritoneal dialysis (PD) and conservative treatme...

05/05/2021
Case Report

Unusual and severe peripartum cardiomyopathy: A case report

Lamanna B, Vinciguerra M, Crupano F, Cicinelli R, Cicinelli E and Vimercati A

Abstract

Peripartum cardiomyopathy (PPCM) is a relatively rare cardiac disease that manifests in the final stage of pregnancy and in the first months after delivery in women with no preexisting heart disease. Many etiological processes have been suggested: viral myocarditis, abnormal ...

05/05/2021
Clinical Image

Vulvar lipoma: A rare tumour

Aarti Chitkara*

A 26 year nulliparous woman presented to the OPD with complaint of painless swelling in the vulva for the last 1.5 years which gradually increased in size causing difficulty in walking. Physical examination revealed a well-defined soft, non-tender ellipsoidal swelling with smooth margins in vulva...

05/05/2021
Case Report

Menstruating primary umbilicus cutaneous endometriosis: A case report and review of literature

Idowu Pius Ade-Ojo* and Oluwadare Martins Ipinnimo

Abstract

Primary umbilical cutaneous endometriosis is a rare umbilical endometrioma that affects women who are within the reproductive age group. It may be associated with infertility and severe dysmenorrhea and can be difficult to diagnosed in an asymptomatic patient.

We re...

05/05/2021
Case Report

Pneumocephalus following labour epidural analgesia, a rare case report

Shagufta Rafiq*, Ibrahim Abbasher, Sadia Anwar, Ammara Ahmad, Bushra Aziz and Branko Denona

Abstract

The lumbar epidural analgesia is commonly used for labour analgesia. The “loss of resistance to air” LORA technique is commonly used for recognition of epidural space. One of the rare complications of this technique is Pneumocephalus (PC). We want to present a cas...

05/04/2021
Research Article

Determinants of health seeking behaviour of women with obstetric fistula in south- south and south east, Nigeria: A review of the impact of availability and quality of health care services through a cross-sectional study

Peters Grace E*, Ononokpono Dorathy N, Willson Nsikanabasi U, Oko Nnabuike I and Peters EJ

Abstract

Background: Obstetric fistula is a condition that results from obstructed labour, which occurs when the baby cannot pass through the mother’s birth canal because it either does not come head first or is too large for her pelvis. Prompt medical intervention, often includ...

04/30/2021
Case Report

Oncocytic papillary cystadenoma of right laryngeal ventricle

Tomasz Ścięgosz*, Renata Kwiatek, Izabela El-Hassanieh and Piotr Ziółkowski

Abstract

A case of oncocytic papillary cystadenoma in a 72-year old woman, a rare tumor of laryngeal seromucinous glands of unclear nature is presented. The patient had a history of chronic inflammation of laryngeal mucosa and both her age and tumor location were typical. The lesion w...

04/30/2021
Research Article

Donor profile and trends of eye donation in Central India

Neha Singh Jat*

Abstract

Background: The present study was conducted to study the donor profile and to assess the trends of cornea donation.

Methodology: This was conducted as a hospital based cross sectional study at a tertiary care centre in Central India for a period of 5 years. Data was...

04/30/2021
Clinical Image

58-year-old male patient who came to the dermatology service for a clinical picture

Francisco Javier Torres-Gómez*

58-year-old male patient who came to the dermatology service for a clinical picture consisting of generalized erythematous scaly and pruritic lesions of 2 years of evolution. The clinical judgments provided were: pityriasis versicolor, drop psoriasis, pityriasis rubra pilaris and secondary syphil...

04/28/2021
Research Article

Drug Eruptions at Patients in Consultation at the Dermatology Department of the Dermatology Teaching Hospital in Bamako, Mali: Epidemiological, Clinical and Etiological Study

Yamoussa Karabinta*, Mamadou Gassama, Aboubakar Hemedi Gassama, Adama Dicko, Hawa Sanogo, Karambe Tenin, Chata Traoré, Mamourou Diakité, Chaka Koné, Sounkalo Dao, Yannick Mukendi, Moussa Savané and Faye Ousmane Faye

The administration of a drug substance is an essential step in the management of a patient. It aims either to cure the patient, to prevent a given disease or sometimes to help with the diagnosis. Unfortunately, the action of the drug can go beyond the desired effect, and cause skin-mucous acciden...

04/29/2021
Prospective

Psychoanalysis of the doctrine of acute pneumonia

Igor Klepikov*

It is difficult to predict how the founder of psychoanalysis, Sigmund Freud, would react to an attempt to link his theory and the method of treating mental disorders based on it [1], with such a purely physical disease as acute pneumonia (AP).

04/28/2021
Research Article

Incidence of hepatitis B and hepatitis C in Pediatric ward in 2ed March teaching hospital, Sebha: South of Libya

Shaban R Bagar, Marei A Altayar, Idress H Attitalla*, Abdlmanam Fakron and Hosam B Bahnosy

Abstract

Objective: to determine the incidence of HBV and HCV in pediatric ward.
Sitting: 2ed March teaching hospital, sebha Libya.

Materials and Methods: this was a prospective hospital base study of pediatric cases admitted to 2ed March teaching hospital during a pe...

04/29/2021
Review Article

Pre-eminence and comparative analysis of skin and surface disinfectants: A systematic review to pave the way for SARS-CoV-2 prevention

Anupam Raja, Saifuddin PK, Nishant Shekhar, Harvinder Mann, Pholen Sarma, Ajay Prakash and Bikash Medhi*

Abstract

More than 200 countries have been devastated by the SARS-CoV-2 pandemic. The health workers exposed to SARS patients have been confirmed to be infected with coronavirus (SARS-CoV-2), regardless of the degree of their exposure. The increasing complexity of virus existence and ...

04/28/2021
Review Article

A systemic review on various pertinences and simulations of rotavirus

Sameer Sharma* and Seema Rani Padhiary

Abstract

Rotavirus induced disease are a main source of dreadful, serious and drying out gastroenteritis in kids (less than five years old). Instead of the worldwide presentation of immunizations for rotavirus longer than 10 years back, rotavirus infections still result in more than 2...

04/28/2021
Opinion

Precision and personalized vaccines needed to face COVID-19 pandemic

Dahmani Fathallah M*

Among the abounding lessons we learned from the SARS-C0V-2 pandemic is the uttermost determinant that people are not equal before the severity of COVID-19. Indeed, the disease course differs with age, gender, ethnicity, underlying clinical conditions and virus variants. O...

04/27/2021
Research Article

HRCT imaging features of systemic sclerosis-associated interstitial lung disease

Zexuan Zhou, Guangfeng Zhang, Ting Xu, Haobo Lin and Xiao Zhang*

Abstract

Background: The aim of the study was to evaluate radiographic features of systemic sclerosis-associated interstitial lung disease.

Patients and methods: 116 patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD) from 2010 to 2019 comprised o...

04/27/2021
Research Article

Nonlinear relationship between blood glucose and 30-day mortality in critical patients with acute kidney injury: A retrospective cohort study

Qilin Yang, Weichao Huang, Xiaomei Zeng, Jiezhao Zheng, Weixiao Chen and Deliang Wen*

Abstract

Background: Acute kidney injury (AKI) is a major health problem affecting millions of people worldwide. Effective preventative and therapeutic treatments remain to be produced. We aim to determine the association between blood glucose and mortality in critical patients with A...

04/27/2021
Research Article

Prognostic factors for chronic kidney disease and end-stage renal disease in patients with lupus nephritis: A retrospective cohort study

Fernanda Nogueira Holanda Ferreira Braga*, Marta Maria das Chagas Medeiros, Antônio Brazil Viana Jr., Levi Coelho Maia Barros, Marcelo Ximenes Pontes, Matheus Eugênio de Sousa Lima, Allyson Wosley de Sousa Lima and Paula Frassinetti Castelo Branco Camurça Fernandes

Abstract

Background: Lupus Nephritis (LN) occurs in approximately half of all patients with Systemic Lupus Erythematosus (SLE) and it is the most common cause of morbidity and mortality in patients with SLE. Factors associated with poor renal outcome vary among studies, and researches...

04/26/2021
Short Communication

RBD targeted COVID vaccine and full length spike-protein vaccine (mutation and glycosylation role) relationship with procoagulant effect

Luisetto M*, Tarro G, Farhan Ahmad Khan, Khaled Edbey, Mashori GR, Ahnaf Ilman, Yesvi AR and Latyschev OY

Abstract

Related COVID vaccine production many different strategies was followed by the producers.

Observing some rare event of thrombosis after some COVID-19 vaccination, it is interesting to verify if the Target used for the manufacturing can be involved in a different pro...

04/26/2021
Review Article

Could apple cider vinegar be used for health improvement and weight loss?

Alexander V Sirotkin*

Summary

This non-systematic review outlines the current knowledge concerning provenance, chemical composition and properties of apple cider vinegar, its general health effects, as well as the currently available knowledge concerning its action on fat storage, physiological mechanisms ...

04/26/2021
Case Report

A case report: Electrochemical impedance spectroscopy as an Al-ternative for cell counting chambers of yeast (Saccharomyces cerevisiae) for brewery applications

Georg Christoph Brunauer*, Alina Meindl, Bernhard Rotter, Alfred Gruber and Christoph Slouka

Abstract

Advanced technologies, such as electrochemical impedance spectroscopy (EIS), are a valuable tool which can enhance and simplify the industrial process monitoring if used correctly. State-of-the-art approaches for screening the cell growth of for example yeast during the brewi...

04/28/2021
Research Article

Predominance of fetal malformations among pregnant women: A multi-centric observational study

Sayed Mohamed Sayed, Ahmed Khedr Khalifa, Nesreen Abd El Fattah Abd Allah Shehata*, Mohamed AM Eweis and Sherwet M Shawky

Abstract

Objective: To observe the predominance of fetal anomalies in pregnant women in a multi-centric setting.

Methods: This prospective observational study included 20225 pregnant women who came for antenatal care in University Hospital and fetal medicine units from 2016 ...

04/26/2021
Case Report

A case report of uterine inversion after home delivery

Sena-Martins M*, Tadini V, Bolsonaro-Guilherme B, Mariani-Neto C, Pires ABN, Lucato LL, Soares AN, Xavier JC, Teixeira BACB, Faro SL and Silva TB

Abstract

Puerperal acute uterine inversion is a rare obstetric condition observed as a serious complication during the third stage of labor. Reported as one of the causes of postpartum haemorrhage, it commonly requires quick diagnosis and surgical treatment in order to reduce morbidit...

04/20/2021
Research Article

Venomics and antivenomics data: Current and future perspective

Soodeh Omidi, Masoumeh Mehrpouya, Morteza Oladnabi*, Abbas Azadmehr, Fatemeh Kazemi-Lomedasht and Najmeh Yardehnavi*

Abstract

Venom has a very complex and exclusive nature which has been introduced by recent advances in omics technologists. These methods have revealed a new insight into venom studies as venomics. Envenoming by venomous animals is a global concern due to the distribution of important...

04/26/2021
Research Article

Endovascular treatment experience in acute ischemic stroke

Hacı Ali Erdoğan, İbrahim Acır* and Vildan Yayla

Abstract

Background and Objective: Thrombolytic and mechanical thrombectomy therapies are proven treatment methods in patients with acute stroke. Aim is to share our experience in acute stroke therapy with colleagues.

Material and methods: In this study we evaluated the pati...

04/20/2021
Research Article

Characterization of the immune response in neuroimmune disorders in children

Nicolas Chiriboga, Jennifer Muñoz-Pareja and Jose Irazuzta*

Abstract

Background: A misguided auto-reactive injury is responsible for several types of central nervous system (CNS) conditions in pediatrics. We propose that, in some of these conditions, the adaptive immune system has a common cellular immune pathogenesis, driven predominantly by ...

04/20/2021
Research Article

Regulatory requirements and assessment of scientific research by a psychiatrist when considering the issue of assigning a qualifying doctor`s category

Shapovalova LA, Shapovalov KA* and Shapovalova PK

Abstract

Introduction: In accordance with the requirements for the preparation of a report, a physician must provide information on scientific research in the following sections to obtain a qualification category of a specialist: 6. Scientific and practical work (participation in scie...

04/23/2021
Review Article

Sildenafil citrate in healthy and diseased hearts

Seriki Samuel Adinoyi*

Abstract

Sildenafil citrate is one of the frontline drugs used to manage erectile dysfunction (ED). Chemically, it is described as 1-[[3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H –pyrazolo [4,3-d]pyrimidin-5-yl)-4 ethoxyphenyl] sulfonyl]-4-methylpiperazine citrate (C22H30N6O4...

04/16/2021
Case Report

pVAD-assisted left main DK-Crush Bifurcation PCI Post-ViV TAVR

Anshuman Das, Maria Isabel Camara Planek and Steve Attanasio*

Abstract

We describe successful percutaneous coronary intervention (PCI) of significantly diseased ostial left main (LM) and distal LM bifurcation (Medina 1,1,1) in a patient with a reduced left ventricular ejection fraction and a recent valve-in-valve balloon-expandable TAVR using th...

04/16/2021
Clinical Image

Total aortic occlusion associated with SARS-CoV-2 (COVID-19) infection: Video Image

Yasin Kilic, Hakan Usta, Izatullah Jalalzai, Ferhat Borulu and Bilgehan Erkut*

Abstract

Acute pulmonary damage and vascular coagulopathy appear to be frequent in patients with SARS-CoV-2 infection relation to corona-virus. The inflammatory process accompanying the infection and excessive coagulation state is one of the most important causes of patient loss.

04/15/2021
Review Article

Current status, complications and prospects of fecal microbiota transplantation therapy

Tadashi Ohara*

Abstract

Currently, the emergence of highly virulent mutants in Europe and the United States has caused refractory recurrent Clostridium difficile infection (RCDI) to be a problem in clinical practice. In 2013, the Netherland group demonstrated breakthrough therapeutic efficacy in fec...

04/14/2021
Research Article

Impact of amitriptyline on learning and memory

Mfem CC and Seriki SA*

Summary

Background/aim: Amitriptyline belongs to class of known as tricycline antidepresant (TCA) that is being used to treat anxiety and depressive states. It may help improve mood and feelings of well-being, relieve anxiety and tension, help to improve sleep and increase energy leve...

04/26/2021
Case Report

Transoral laser resection of a large schwannoma in the retropharyngeal space

Payman Dabirmoghaddam, Zahra Danesh* and Amirmohammad Danesh

Abstract

Introduction: The contents of the retropharyngeal space are limited to fat and retropharyngeal nodes. Primary tumors originating from the retropharyngeal space are rare, therefore, the existence of schwannoma in the retropharyngeal space is infrequent.

Method: This ...

04/13/2021
Review Article

Will the pill help defeat the coronavirus?

Igor Klepikov*

The onset of the pandemic has caused widespread concern about the rapid spread of the infection and serious concern about the lack of specific treatment for it.

04/13/2021
Case Report

Osteoclastic giant cell variant of urothelial carcinoma in a COVID- positive patient: A rare variant in an unusual circumstances

Chanchal Rana*, Divya Goel, Akanksha Singh, Suresh Babu and Vishwajeet Singh

Abstract

Bladder carcinomas have a great propensity for divergent differentiation with more that 90% being Transitional cell carcinoma.  Several histological variants have been have described so far; they are not only morphologically unique but also have significant prognostic an...

04/22/2021
Short Communication

A Time: Philosophy of Science

Berov G Lyubomir*

Abstract

Dear reader, isn’t it time to turn things around and allow TIME to take its rightful place? In a nutshell, I believe Time should be considered as the primary energy that has created the whole material world and governs the continuous changes in it. In my article “...

04/13/2021
Research Article

Coronavirus COVID-19 surface properties: Electrical charges status

Luisetto M*, Tarro G, Khaled Edbey, Farhan Ahmad Khan, Ahnaf Ilman, Yesvi AR, Nili BA, Fiazza C, Mashori GR and Latyshev OY

Abstract

Aim of this work is to analyze the coronavirus viral surface properties related the pattern of electrical features.

This chemical physical property is relevant and crucial to set profile of diffusion, severity of disease, efficacy of therapeutic strategy and in orde...

04/21/2021
Research Article

A Study of Doppler velocimetry in pre-eclampsia patients, and their perinatal outcome

Rahul Khatri*, Bhoomika Jain, Sabrina Mhapankar and Sushil Kumar

Abstract

Pre eclampsia and IUGR are important causes of maternal and perinatal morbidity and mortality. Pre eclampsia is a multisystem disorder, in normal pregnancies trophoblastic invasion transforms high resistance spiral arteries into low impedance uteroplacental circulation. This ...

04/21/2021
Research Article

Comparative study of continuous method and interrupted method of episiotomy in terms of healing of the surgical wound

Rahul Khatri*, Bhoomika Jain, Sabrina Mhapankar and Sushil Kumar

Abstract

Episiotomy is a most commonly performed minor procedure. There are various type of episiotomy suturing, in this study two most common types of episiotomy suturing techniques were compare in terms of healing rate. This study concluded that the continuous method of episiotomy s...

04/22/2021
Case Report

Diffuse alveolar hemorrhage: Unusual presentation of systemic lupus erythematosus

Zajjari Yassir*, Sobhi Aya, Aatif Taoufiq, Azizi Mounia and El Kabbaj Driss

Diffuse alveolar hemorrhage (DAH) is a rare complication of systemic lupus erythematosus (SLE) and carries a high mortality.

It was first described by Osler in 1904 as the most devastating pulmonary complication of SLE.

We describe a case of a 23-year-old girl recently diagnos...

04/15/2021
Research Article

Factors associated with diagnostic delay in children with Wilms’ tumor

Francisca Norma Gutierrez, Guilherme de Aguiar Moraes, Marilia Fornaciari Grabois, Sima Ester Ferman and Adauto Dutra Moraes Barbosa*

Abstract

Background: In Wilms’ tumor, the time elapsed between clinical diagnosis and the start of treatment is clearly associated with morbidity and mortality. As treatment delay can influence patient survival, identification of possible causes can mitigate the consequences ari...

04/14/2021
Research Article

Efficacy of intravenous immunoglobulins in the prophylaxis of neonatal sepsis

Sharif S*, Bloomer C, Al Assaf N and Khan R

Summary

Despite critical care advances, robust antibiotic therapy and improved strategies in early detection and prevention of infection, the incidence of morbidity and mortality from neonatal sepsis worldwide in preterm and low birth weight neonates remains overwhelmingly high. Neona...

04/12/2021
Research Article

Integration of GC-MS in identification of possible final metabolites from phytase production in Pichia Pastoris based on sorbitol induction optimization

Ndayambaje Jean Bernard*, Habarurema Gratien, Habinshuti Janvier, Ingabire Angelique, Ingabire Ange Sabine, Martin Patrick Ongol and S Meenakshisundaram

Abstract

The isolation of phytase using Pichia Pastoris under methanol/sorbitol co-feeding induction technique was investigated. The biological activity of extracellular phytase after optimization with co-substrates induction in 4 liters fermentor (NBS) increased to 13250 U/ml. This l...

04/12/2021
Mini Review

Targeted and non-targeted effects of radiation in mammalian cells: An overview

Rita Ghosh* and Surajit Hansda

Abstract

Radiation of different wavelengths can kill living organisms, although, the mechanism of interactions differs depending on their energies. Understanding the interaction of radiation with living cells is important to assess their harmful effects and also to identify their therap...

04/08/2021
Research Article

Immunological background for treatments with biologicals in CRSwNP

L Klimek*, J Hagemann, I Casper, T Huppertz, A Bedbrook and J Bousquet

Abstract

Background: Chronic rhinosinusitis (CRS) is a heterogeneous and multifactorial inflammatory disease of the nasal and paranasal mucosa. To date, no internationally standardized uniform classification has been developed for this disease.
Usually, a phenotype classificati...

03/17/2021
Research Article

Fecal storage condition induces variations of microbial composition and differential interpretation of metagenomic analysis

Gihyeon Kim, Kyoung Wan Yoon, Changho Park, Kyu Hyuck Kang, Sujeong Kim, Youngmin Yoon, Sang Eun Lee, Yeongmin Kim and Hansoo Park*

Abstract

Advances in metagenomics have facilitated population studies of associations between microbial compositions and host properties, but strategies to minimize biases in these population analyses are needed. However, the effects of storage conditions, including freezing and prese...

04/09/2021
Research Article

Influence of retreatment in the formation of dentinal microcracks in mandibular molars filled with a calcium silicate based sealer

Luciana da Cruz Ribeiro Jorge, Fabiola Ormiga, Aline Neves, Ricardo Tadeu Lopes and Heloisa Gusman*

Abstract

Introduction: In endodontically treated teeth, dentinal defects such as microcracks can progress to a vertical root fracture and lead to tooth loss.

Objective: The present study aimed to evaluate, by micro-computed tomography analysis, the formation of dentinal micr...

04/09/2021
Research Article

Synergistic interactions of sperm impairing bacteria: Impact on pregnancy outcome in mouse model

Isheeta Jangra, Aditi Chauhan and Vijay Prabha*

Abstract

Earlier in our laboratory, the role of various individual sperm impairing microorganisms on sperm parameters and female infertility has been elucidated at higher doses. As, multiple bacterial species tend to exert more pathogenic effect in comparison to single organism hence,...

04/08/2021
Research Article

Collecting duct PGE2 responses reduce water loss with empagliflozin in mice with type 2 diabetes mellitus

R Nasrallah, J Zimpelmann, V Cheff, JF Thibodeau, KD Burns and RL Hébert*

Abstract

Introduction: Sodium-glucose cotransporter 2 inhibitors such as empagliflozin (EMPA) protect against diabetic kidney disease. Prostaglandin E2 (PGE2) the main renal product of cyclooxygenase-2, inhibits vasopressin (AVP)-water reabsorption in the collecting duct (CD). The nov...

04/08/2021
Short Communication

Burden and depressive symptoms in health care residents at COVID-19: A preliminary report

Daniela Betinassi Parro-Pires*, Sérgio Henrique de C Matias Barros, Fernanda Sabina HD Araújo, Daniel Zandoná Santos, Luiz Antônio Nogueira-Martins and Vanessa de Albuquerque Citero

Abstract

This paper focuses on the mental health burden on medical and healthcare residents during the 1st wave of COVID-19 pandemic crisis in 2020 describing the activities of a mental health service for residents (NAPREME) in a public university, UNIFESP, Sao Paulo, Brazil; and a pr...

04/08/2021
Research Article

Role of toll-like receptors and their ligands in adipocyte secretion

A Mishra*, AV Shestopalov, AM Gaponov, IA Alexandrov and SA Roumiantsev

Abstract

Background: Adipose tissue is one of the main sites of energy homeostasis that regulates whole body metabolism with the help of adipokines. Disruption in its proper functioning results in adipose tissue remodeling (primarily hypertrophy and hyperplasia) which directly influen...

04/08/2021
Mini Review

Transcriptional profile of bovine preimplantation development selected based on G6PDH activity

Nasser Ghanem*, Romysa Samy, Eman Kh Kassab, Beshoy SF Khalil, Aya Ahmed Kordy, Marwa MH Said, Nouran S Rashed, Md Fakruzzamana and Kong IK

Abstract

The oocyte is the female gamete that contributes not only half of the genetic material but also all of the cytoplasm to the zygote, supplying the transcripts, proteins, mitochondria and other components necessary for early embryonic development. The intrinsic oocyte quality i...

04/07/2021
Research Article

Autoimmune hemolytic anemia in COVID-19 patients, the « transmissible » direct Coombs test

Alice Brochier*, Julien Cabo, Claudine Guerrieri, Leïla Belkhir, Pierre-François Laterre and Véronique Deneys*

Abstract

Background: Like other viruses, the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) appears to be responsible for several autoimmune complications. The occurrence of autoimmune hemolytic anemia has been described in several case reports. This AIHA was also notice...

04/07/2021
Research Article

Clinical and epidemiological differences in the course of psoriasis in children depending on Vitamin D levels and genotypes of the TaqI polymorphic variant of the VDR gene

Murzina Elvina*

Abstract

When grouping children with psoriasis depending on TaqI (T/C) genotypes of the VDR gene, the youngest age of disease onset and the longest duration of dermatitis (5.60 ± 0.77 years and 4.90 ± 0.68 years, respectively) showed up in case of the CC genotype. In case ...

04/07/2021
Research Article

Overview on liquid chromatography and its greener chemistry application

Adel E Ibrahim, Magda Elhenawee, Hanaa Saleh and Mahmoud M Sebaiy*

Abstract

This literature review is concerning with liquid chromatography specifically high performance liquid chromatography (HPLC), Ultra high performance liquid chromatography (UHPLC), chromatography theory, chromatographic parameters, monolithic columns, principles of green chemist...

04/07/2021
Research Article

Usefulness of salivary cortisol as a marker of secondary adrenal insufficiency in paediatric patients

Laura Capdevila, Ariadna Borràs, Eugenio Berlanga, Judith Sánchez- Manubens, Josefa Rivera and Raquel Corripio*

Abstract

Background: The main cause of adrenal insufficiency (AI) in paediatric patients is prolonged treatment with corticosteroids. Determination of plasma cortisol (PC) during ACTH test is the most used adrenal function indicator in clinical practice. However, determination of sali...

04/02/2021
Case Report

Bilateral transient osteoporosis of the hip with unilateral fracture in a 40 years old pregnant woman

Sheila Shytaj*, Vanna Bottai, Fabio Cosseddu, Roberta Cifali, Silvia De Franco and Michelangelo Scaglione

Summary

Purpose: Some physiological events in women’s life such as pregnancy and lactation can be associated to a condition known as Transient Osteoporosis of the Hip (TOH); if not promptly diagnosed it can lead to significant consequences such as femoral neck fracture. In this ...

04/09/2021
Review Article

Quantum analysis of sub harmonic generation with two-mode coherent light

Alemayehu Getahun* and Habtamu Dagnew

Abstract

In this work the statistical and squeezing properties of light-driven by sub-harmonic generation with two-mode coherent light are studied. With interaction Hamiltonian of both two-mode coherent and sub harmonic generation, we have driven master equation of system under consid...

04/07/2021
Review Article

Tunable induced transparency and Fano-resonance in double cavity optomechanical system

Anjan Samanta*, Kousik Mukherjee and Paresh Chandra Jana

Abstract

We analyze optomechanically induced Transparency and asymmetric Fano-line shape Profile in a two-mode cavity system, coupling at weak and strong coupling regimes. The model system consists of one mechanical mode and two optical modes. The transmission shows nonreciprocal beha...

04/05/2021
Research Article

Influence of high frequency rotating magnetic field on the effect of heating magnetic fluid

Andrzej Skumiel*

Abstract

The article describes the necessary conditions for the phenomenon of thermal energy release in a magnetic fluid placed in a high-frequency rotating magnetic field. The minimum amplitude of the magnetic field was calculated and the thermal power released (by the rotating spher...

04/05/2021
Research Article

Radionuclide contents in yam samples and health risks assessment in Oguta oil producing locality Imo State Nigeria

Nnamdi Norbert Jibiri and Benedict Chukwudi Eke*

Abstract

Oguta LGA is surrounded by 44 oil wells located around different communities. Preliminary investigations indicated that crude wastes were not properly managed and oil spillage occurred regularly in the LGA. Therefore, assessment of both radionuclide contents in yam matrix and...

04/02/2021
Research Article

Silicon rates and beneficial microorganism on blast suppression and productivity of upland rice

Alan Carlos Alves de Souza*, Marta Cristina Corsi de Filippi, Adriano Stephan Nascente, Anne Sitarama Prabhu and Eduardo Alves

Abstract

One of the primary constraints in upland rice cultivation is the disease blast (Magnaporthe oryzae), which can provide reduction up to 100% of the grain yield The use of silicon with beneficial microorganisms (bioagents) can be an alternative for the control of this disease a...

03/25/2021
Research Article

Partial SHOX duplications associated with various cases of congenital uterovaginal aplasia (MRKH syndrome): A tangible evidence but a puzzling mechanism

Daniel Guerrier* and Karine Morcel

Abstract

The Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome is the most severe form of congenital malformation of the inner female reproductive tract. It is diagnosed as such when the uterus, the upper vagina and optionally the Fallopian tubes are absent. It accounts for approxim...

03/24/2021
Case Report

A case report on Meigs’ syndrome and elevated serum CA-125: A rare case report

Divya Khanduja* and NC Kajal

Abstract

Meigs syndrome is an uncommon presentation, where a benign ovarian neoplasia presents along with ascites and pleural effusion. About 1% of ovarian neoplasia can present as Meigs syndrome. Patients with Meigs’ syndrome and elevated serum CA-125 are not frequently reporte...

03/17/2021
Research Article

Comparative Osteometric study of some selected bones of local domestic turkey and guinea fowl

Bello Abdulrahman* and Aisha Yusuf

Abstract

The research was conducted in the Gross section of Veterinary Anatomy laboratory with the aim of preparation and comparing some skeleton bones of local domestic turkey and guinea fowl. Samples were purchased, sacrifice, feather and excess flesh were removed and boiled using w...

04/08/2021
Review Article

The relationship between it use and aggression in Pakistani youth

Waqar Husain* and Sehrish Mobeen

Abstract

The use of Information Technology (IT) has made our live comfortable at present however, it has also generated certain health concerns. The disproportionate exercise of IT, with indication to accessible literature, has been consistently interrelated with psychopathological in...

04/07/2021
Research Article

Suicide, the main cause of referral of patients from a general hospital for psychiatric evaluation

Elena Gómez, Marianela Guzmán and Oriol Yuguero Torres*

Abstract

Introduction: Psychiatric emergencies constitute between 1% - 10% of general emergencies in Spain, of which a quarter will end up being hospital admissions. There is little literature on patients who are referred from general to specialized hospitals.

Methods: Cross...

03/18/2021
Review Article

Explicating the presentations of Acanthamoeba keratitis with special concern in the COVID-19 pandemic ambient

Chrysanthus Chukwuma Sr*

Abstract

This article presents an overview of information regarding Acanthamoeba keratitis per epidemiology, host-pathogen interactions, clinical manifestations, risk factors, environmental implications, diagnosis, treatment and management as well as COVID-19 characteristics which may...

03/01/2021
Research Article

Evaluation of endothelial function in obese children and adolescents

Hacer Efnan Melek, Ayça Törel Ergür* and Gökçe Kaan Ataç

Abstract

Introduction: Obesity defined as increased fatty mass is progressively rising in recently, even though its affects begins to all systems in childhood and adolescence periods, the most important morbidity and mortality reason of obesity is its effects on the cardiovascular sys...

03/31/2021
Research Article

Which women uses social Internet networks during pregnancy?

Sylvie Viaux-Savelon*, Catherine Fouillet, Nicolas Bodeau and Jacky Nizard

Abstract

Internet has become an important part of our life, including during pregnancy where it is broadly used to find information (84%). The aims of this study were (1) to describe the proportion of women using Internet Social Networks (ISN) concerning their pregnancy, during pre or...

03/17/2021
Review Article

Laparoscopic staging of borderline ovarian tumours – Technique and results

Klimatsouda M, Donoudis C, Kontopoulos G and Daponte A*

Abstract

Borderline Ovarian Tumors (BOT) tend to present more frequently nowadays, especially in younger women. Furthermore fertility preservation and laparoscopic management is often desired and therefore appropriate counselling is challenging and the treatment selection must be made...

03/29/2021
Review Article

Rationality and irrationality in the use of antibiotics in the epiclatino Latin American Neonatal Units

Angela B Hoyos*

Abstract

Background: Recent years have seen chaos in the neonatology use of antibiotics with diverse opinions and recommendations in international guidelines and societies. This has created great uncertainty in which cases to use, for how long, and which tests apply to make these deci...

03/29/2021
Short Communication

Atypical presentation of congenital pneumonia: Value of lung ultrasound

Virginie Meau-Petit* and Grenville F Fox

A term neonate was transferred from a Local Neonatal Unit to our surgical Neonatal Intensive Care Unit on Day 2 due to abdominal distension with radiological appearances suggestive of intestinal obstruction. He was born by Caesarean section with no risk factors for sepsis.

03/25/2021
Research Article

Factors associated with zinc prescription practice among children with diarrhea who visited public health facilities in Addis Ababa, Ethiopia: A cross sectional study

Abenezer Woldegebriel*, Mesfin Beyero and Alemneh Kabeta Daba

Abstract

Background: Diarrhea and nutrient deficiency worsen each other, and zinc is recommended to be included in clinical management of diarrhea. Therefore, this investigation was done to assess zinc prescription practice to children with diarrhea, identify factors associated with z...

03/25/2021
Research Article

An Audit on the implementation of administering Ondansetron in children with acute gastroenteritis and its effect on admission rate

Saskia D’Sa*, Ahad Hussain, Mushtaq Hussain, Zahir Afridi, John Twomey and Irfan Ahmed

Abstract

Acute gastroenteritis (AGE) is a common presenting complaint in paediatrics. Most often, the reason for admission into hospital is to initiate intravenous rehydration in patients with severe dehydration and inability to tolerate oral intake. We found that Ondansetron acts as ...

03/23/2021
Research Article

An experimental study on effects of fluoridated water on Abelmoschus esculentus var. Soh-198 (Lady Finger)

Arshi Iram*

Abstract

An experimental study of fluoride (F) accumulation in Abelmoschus esculentus var. Soh-198 and its effect on the growth and crop yield was conducted in a pot experiment. Eight different concentrations of F in the water were used for irrigation ranging from 2 to 14 ppm with dis...

03/23/2021
Mini Review

Phytochemicals candidates as promising preventives and/or curatives for COVID-19 Infection: A brief review

Selma Hamimed*, Nejib Jebli, Rayene Hamimed, Ahmed Landoulsi and Abdelwaheb Chatti

Abstract

The outbreak of new coronavirus acute respiratory disease (SARS-CoV-2) has been a major global challenge for the scientific community to save humanity. While, the unviability of the vaccine keeps most classes of society, especially African countries, suffer from the healthcar...

03/19/2021
Short Communication

Patterns of drugs and alcohol abuse among youth

Tamar Ruth Orowitz*

Abstract

The study attempted to answer several questions: Does the cultural and social background of immigrant youth from the Former Soviet Union (FSU) affect their use of addictive substances? Do these youth show distinctive patterns of drug and alcohol abuse? Do the addictive substa...

03/19/2021
Case Report

Regeneration of deep intrabony periodontal defects with enamel matrix derivative: A case report

Lopes Otão P and Mascarenhas P*

Summary

A clinical case of treatment of two severe intrabony defects on the aesthetic zone is reported and followed for one year.

The biomaterial of choice was enamel matrix derivative (Emdogain®; Straumann™) alone with a preservation papilla flap and a minimally i...

03/23/2021
Review Article

Cortical spreading depolarizations in the context of subarachnoid hemorrhage and the role of ketamine

Leandro Custódio do Amaral*

Abstract

Delayed cerebral ischemia (DCI) is one of the main complications of spontaneous subarachnoid haemorrhage and one of its causes is the cortical spreading depolarizations (CSDs). Cortical spreading depolarizations are waves of neuronal and glial depolarizations in which there i...

03/26/2021
Research Article

Ambivalent sexist attitudes of young adolescents from the province of Jaén: Regarding the use of sexual and/or pornographic content on the internet

María José Calero*, Ana Raquel Ortega Martínez and José Luis Castillo Galán

Abstract

Knowing the possible origin of sexist attitudes in adolescents is essential when educating them to avoid gender violence derived from them. Nurses have an important role in education for the health of children and adolescents, so we must study the risk factors that lead to th...

03/23/2021
Research Article

Experiences of patients with lung cancer receiving concurrent chemo-radiotherapy

Eunsook Choi* and Sunhee Park

Abstract

Purpose: In an aspect of qualitative treatment, this research gathered lung cancer patients’ actual experiences to understand deeply, such as their expectation for treatment results, their difficulties during treatment, and their various requests to their family and med...

03/22/2021
Letter to the Editor

Why? It is the question that I ask myself every day, every hour, every second...

Francisco Javier Torres-Gómez*

It is the dart that penetrates deep into my soul, every time I see with my own eyes how the incidence of cancer has grown in recent years.

03/16/2021
Review Article

Evidence-based primary care approach to treating people with COVID-19 infection to prevent life-threatening complications: A review of the evidence for practical application in a clinical setting

Thomas A Sharon*

Abstract

The NIH has published treatment guidelines for treating COVID-19 patients in the hospital. However, as of this writing, there are no established protocols for treating COVID-19 positive patients in primary care. Accordingly, this investigator has taken on the task of reviewin...

03/26/2021
Research Article

Environmental influence on blood serum detection using ultraviolet 365

Kelly P Kearse*

Summary

The major use of alternative light sources (ALS) in the evaluation of bloodstains has been primarily focused on detection of whole blood, with relatively little attention to visualization of blood serum. Serum may become separated from blood pools during clotting, and because ...

03/16/2021
Research Article

Economic disparities and suicides: The dynamic panel data analyses of 50 states in the United States

Bruce Q Swan*

Abstract

The economic inequalities associated with suicide risks among 50 states in the United States were identified in this paper to form the dynamic panel data set from 1981 to 2016. The effects of growing income inequalities on suicides in the Unites States were estimated using th...

03/12/2021
Research Article

Sequence-independent single-primer-amplification (SISPA) as a screening technique for detecting unexpected RNA viral adventitious agents in cell cultures

Davood Bahador, Ashraf Mohammadi, Abolhasan Foroughi and Behnam Alirezaie*

Abstract

The sequence-independent, single-primer amplification (SISPA) enables the random amplification of nucleic acids, allowing the detection and genome sequencing of different viral agents. This feature of SISPA method provides evidence for application of it in monitoring the presen...

03/18/2021
Clinical Image

Aortic dissection complicating carotid dissection and myocardial infarction

Chun-Cheng Chen, Hung-Wen Tsai and Sung-Yuan Hu*

A 58-year-old hypertensive man presented to our insti-tution with acute chest pain and dizziness. Electrocardiogram revealed inferior wall myocardial infarction with suspected right ventricular involvement (Figure 1A).

03/18/2021
Clinical Image

Ketamine-related uropathy and cholangiopathy

Yi-Hsuan Chen, Shian-Shiang Wang and Sung-Yuan Hu*

A 23-year-old man had a 2-year history of ketamine abuse and presented intermittent abdominal pain, urinary urgency and dysuria for one year.

03/09/2021
Clinical Image

Millian´s ear sign: Bilateral ear erythema

Roberto Benavides Arenas* and Juan Camilo Jaramillo

A 79 years old woman presented with one-day history of pain, redness, pain and swelling without discharge in her left ear, later her right ear started with the same symptoms as in her contralateral ear spreading around the scalp and the forehead (Figure 1), she denied fever, or other constitution...

03/24/2021
Research Article

Abdominal obesity in predicting myocardial infarction risk. Waist-to-Hip Ratio: The metric that confused cardiology worldwide for a long time

Angel Martin Castellanos*

Important differences has been found in assessing the effects of obesity on cardiovascular disease (CVD) risk [1]. Interestingly, accurate estimation of the body composition (BC) is highly relevant from a public health perspective [2], and it has the importance of being essential in establishing ...

03/19/2021
Review Article

Management of hypertension in Nigeria: The barriers and challenges

Nelson I Oguanobi*

Abstract

In recent years there has been increasing concern about the growing burden of cardiovascular disease (CVD) in developing countries. Systemic hypertension remains the commonest form of CVD and is identified as a key modifiable risk factor for cardiovascular morbidity and morta...

03/26/2021
Letter to the Editor

Criteria for paediatric oral liquid form

Daniela Gavrus, Ferran Bossacoma Busquets*, Josep Maria Català, Joan Lluis Vinent Genestar and Miquel Villaronga Flaque

Paediatric hospitals frequently have to face the lack of commercially available medicines suitable or even licensed for their use in paediatrics. Thus, only one-third of all medicines approved by the European Medicines Agency over the period of 1995 to 2005 were licensed for use in children [1].<...

03/25/2021
Research Article

COVID-19 immunologic and toxicological implication: Innate immune sensor and immune escape

Luisetto M*, Ahnaf Ilman, Farhan Ahmad Khan, Khaled Edbey, Gamal Abdul Hamid, Mashori GR, Nili BA, Fiazza C, YesvI R and Latishev Yu O

Abstract

Related COVID-19 and new Variant and treatment like vaccine it is relevant to deeply verify the immunologic implication and in a special way regarding the innate immune sensor system and the evasion of the immune system.

This can be crucial to search for new strateg...

03/08/2021
Case Report

Prostate cancer-associated thrombotic microangiopathy: A case report and review of the literature

HHS Kharagjitsing*, PAW te Boekhorst and Nazik Durdu-Rayman

Abstract

Background: Thrombotic microangiopathy (TMA) is a rare and life-threatening complication of prostate carcinoma. Whether plasma exchange has a role in treatment remains a subject of debate. Here we present a case followed by a systematic review of the literature on this subjec...

03/17/2021
Case Report

Giant hepatic cystadenoma mimicking a hydatid cyst: A challenging preoperative diagnosis

Mosaab Ghannouchi, Amina Chaka*, Seifeddine Ben Hammouda, Mohamed Ben Khalifa, Asma Chaouech, Karim Nacef, Kamel Hleli and Moez Boudokhane

Abstract

Biliary cystadenoma is a rare cystic tumor of the liver. It has a high recurrence rate and malignant transformation risk in middle-aged women. Pre-operative diagnosis is difficult because of the lack of clinical, biological and radiological specificity. The confirmation of th...

03/17/2021
Review Article

Prognostic significance of the Central Tumor Size (CTS) in Cervical Cancer (CC) stages IIb and IIIb: What should we do with the FIGO staging system and therapeutic strategies?

Alejandro Soderini*, Alejandro Aragona, Agustin Quintaie, Horacio Moschen and Martín Mendez

Abstract

Cervical cancer constitutes an issue in public health, becoming the leading cause of death by cancer in women between 20-40 years of age in Latin America. In Argentina 5000 new cases are diagnosed each year, where more than 56% are in advanced stages. The aim of the present c...

03/19/2021
Case Report

Cerebral arterial air embolism with anterior spinal cord syndrome after CT-guided hook-wire localization of Lung mass and pulmonary nodule

Noor Sameh Darwich*, Umran Ugur, Mark P Anstadt and Michael J Pedoto

Abstract

Systemic arterial air embolism (SAAE) is a rare but serious complication of CT-guided hook wire localization of pulmonary nodule usually with catastrophic and poor outcome. Hook wire needle localization is done pre-operatively by placing wire around or into the pulmonary nodu...

03/19/2021
Research Article

Higher venom-specific IgE levels differentiate children with previous local large reactions from children with previous systemic reactions of different severity

Pastorello Elide Anna*, Borgonovo Linda, Piantanida Marta, Schroeder Jan Walter, Pravettoni Valerio, Pastori Stefano, Bilo’ Maria Beatrice, Toniato Andrea, Nichelatti Michele, Preziosi Donatella, Aversano Maria Gloria and Farioli Laura

Abstract

Introduction: Risk factors for systemic reactions (SRs) from hymenoptera venom (HV) allergy are well known in the adult population but they have been little studied in the pediatric one.

Method: The aim of our study was to identify risk factors for SRs in a populati...

02/26/2021
Review Article

An update on outpatient competence restoration outcomes: The Washington DC Model

Reston N Bell, Philip J Candilis* and Nicole R Johnson

Abstract

This study provides an update to a previous study exploring time to restoration of adjudicative competence within an Outpatient Competence Restoration Program (OCRP). Authors examined the probability of restoration for individuals referred for outpatient competence restoratio...

03/12/2021
Review Article

Mild to moderate iodine deficiency in pregnancy: A matter of debate

Hossein Delshad and Fereidoun Azizi*

Abstract

During the last few decades painstaking efforts have been made to eliminate iodine deficiency through the world. Nowadays in regions where dietary iodine intake is adequate or borderline, the main focus is increasing dietary iodine supply in the target population during pregn...

03/08/2021
Research Article

Risk of developing eating disorders through the misperception of the body image and the adoption of bad eating habits in a sample of young volleyball athletes

Ramona Fochesato, Sara Guidotti and Carlo Pruneti*

Abstract

Objective: This preliminary study focused on the description of some dysfunctional perceptions of the body image and eating habits in a sample of young.

Methods: The results obtained by 55 amateur and professional volleyball players belonging to volleyball sports cl...

03/02/2021
Research Article

Muscle growth and control of production of sarcomere components

Gerry A Smith*

Abstract

This presentation gives a description of the muscle and sarcomere followed by the main content summarized.

 

03/04/2021
Review Article

Imaging modalities delivery of RNAi therapeutics in cancer therapy and clinical applications

Loutfy H Madkour*

Abstract

The RNA interference (RNAi) technique is a new modality for cancer therapy, and several candidates are being tested clinically. Nanotheranostics is a rapidly growing field combining disease diagnosis and therapy, which ultimately may add in the development of ‘personali...

03/03/2021
Letter to the Editor

Alone in the face of adversity

Francisco Javier Torres-Gómez*

From my desk I could be watching the wind blow or the horses running. Practicing Medicine in a rural setting has these advantages: from time to time you can take the time to admire the beauty that surrounds you in the form of an obligatory pause within a marathon working day, and rest helps refre...

03/03/2021
Case Report

The creative self in anorexics

Dalmotto M* and Fassino S

Abstract

The article describes the interaction of anorexic patients, hospitalized in the Regional Pilot Psychiatric Service for the treatment of Anorexia in the Molinette Hospital of Turin, with the reading volunteering group. On the basis of said interaction, the Creative Self is sea...

03/08/2021
Research Article

Incidence and risk factors of vancomycin-associated acute kidney injury in a single center: Retrospective study

Tanuja Yalamarti, Shahrzad Zonoozi*, Kwabena Adu Ntoso and Pooneh Alborzi

Abstract

Background: There is enough evidence to suggest that vancomycin increases the risk of acute kidney injury (AKI) but the exact mechanism is not well understood. This study aims to understand the incidence of vancomycin-associated acute kidney injury (VA-AKI) among hospitalized...

03/08/2021
Research Article

Forensic analysis of private browsing mechanisms: Tracing internet activities

Hasan Fayyad-Kazan*, Sondos Kassem-Moussa, Hussin J Hejase and Ale J Hejase

Abstract

Forensic analysts are more than ever facing challenges upon conducting their deep investigative analysis on digital devices due to the technological progression. Of these are the difficulties present upon analyzing web browser artefacts as this became more complicated when we...

02/26/2021
Research Article

Pattern of injuries in different types of victims of road traffic accident in central India: A comparative study

Vipul N Ambade*, Sirsat Kunal B and Sharma Manu

Abstract

Death due to road traffic accident (RTA) was one of the leading causes of mortality and morbidity in India. In the present cross-sectional study, only the victim using two-wheelers, four-wheelers, and pedestrians were included for comparison to determine the pattern of injuri...

03/03/2021
Mini Review

Bleeding complications at the access sites during catheter directed thrombolysis for acute limb ischaemia: Mini review

Elias Noory*, Tanja Böhme, Ulrich Beschorner and Thomas Zeller

Abstract

Acute and subacute ischemia of the lower limbs represents a major emergency with a high in-hospital mortality, complication, and leg amputation rates.

Treatment options for acute limb ischemia include systemic anticoagulation, followed by various catheter based opti...

03/02/2021
Research Article

Experimental research on the mechanism of chemical energy conversion to light energy under thermal induction

Jiping Liu*, Zhuqing Fang, Yinjie Wang and Jia Han

Abstract

Since the discovery of glare illuminators, considerable efforts have been devoted to achieving a breakthrough of high light intensity on the order of magnitude. In this paper, we prepared strong flash blinding agents for the first time by using aluminum powder, oxidant, and a...

02/26/2021
Research Article

Antimicrobial resistance of Klebsiella pneumoniae strains isolated from urine in hospital patients and outpatients

Maja Ostojic, Mahir Hubana, Marija Cvetnić, Miroslav Benić and Zeljko Cvetnić*

Abstract

Background: Klebsiella pneumoniae is a bacterial species that often causes infections in humans. Infections occur most frequently in hospitalised or immunocompromised patients and are treated with antimicrobials. In recent decades, K. pneumoniae has developed significant resi...

02/26/2021
Review Article

Chronic fatigue syndrome and epigenetics: The case for hyperbaric oxygen therapy in biomarker identification

Rajit J Shah*

Abstract

Chronic fatigue syndrome (CFS) is a poorly-understood respiratory condition that affects millions of individuals. Hyperbaric oxygen therapy (HBOT) is a treatment option being considered to address CFS as it is suggested to combat fatigue and increase oxygenation. HBOT provide...

02/26/2021
Short Communication

Cyn d 1 airborne allergen in a Southern Brazilian city

Cinthya Covessi Thom de Souza, Nelson Augusto Rosario Filho, Ernesto Akio Taketomi, Juliana Silva Miranda and Ricardo Henrique Moreton Godoi

By researching the factors related to exposure to indoor and outdoor allergens, such seasons, climate changes and particulate matter, allergists can screen the sensitization profile of individuals according to their exposures and conduct preventive treatment and individualized immunotherapy.

02/25/2021
Review Article

Impact of COVID-19 pandemic on anti-microbial resistance and secondary microbial infections

KP Mishra*, Priyanka Mishra, AK Singh and SB Singh

Abstract

Corona Virus Disease-2019 (COVID-19) has become one of the most serious diseases in the history of mankind. It has captured the entire world and solutions are yet to be discovered to fight this global crisis. The outcomes of COVID-19 are influenced by a variety of pre-existin...

02/25/2021
Research Article

A comparative study of single or dual treatment of theranostic 188Re-Liposome on microRNA expressive profiles of orthotopic human head and neck tumor model

Shan-Ying Wang, Liang-Ting Lin, Bing-Ze Linchih, Chih-Hsien Chang, Chun-Yuan Chang, Min-Ying Lin and Yi-Jang Lee*

Abstract

Background: 188Re-liposome has been used for evaluating the theranostic efficacy on human head and neck squamous cell carcinoma (HNSCC) at preclinical stages. Here we furthercompared the microRNA expressive profile in orthtopic HNSCC tumor model exposed to 188Re-liposome.

...

02/23/2021
Case Report

Ipratropium induced bronchoconstriction in a young Asthmatic: A case report

H Aleshaa*, J Collindridge and RK Singh

Acute severe Asthma is a common paediatric emergency managed according to the BTS and SIGN guidelines. They recommend that if initial β2 agonist treatment bears no response, frequent Ipratropium Bromide doses can be given every 20-30 minutes [1]. We present a case of paradoxical bronchospasm...

02/19/2021
Research Article

Fluorinated nematicides: Novel classes in the way

Mohamed S Khalil* and Rasha E Selim

Abstract

The demand on non- fumigant nematicides was strongly increased in the last few years, and this interesting in nematicides are due to farmers are needed for safer pesticides and increasing of the regulatory pressure on many of the traditional nematicides. The control of plant ...

02/18/2021
Research Article

Psychotropic drugs prescription block the positive effects of the doctor-patient communication and relationship

Jose Luis Turabian*

Abstract

The fact that general practitioner (GP) or psychiatrist understands the psychosocial effects of prescribing on the doctor-patient relationship is as important, if not more so, than knowing pharmacology. Any prescription of drugs modifies the doctor-patient relationship. Drugs...

02/16/2021
Case Report

Papillary thyroid cancer and cervical lymph mode metastases – optimal preoperative evaluation

George H Sakorafas*

Papillary thyroid cancer (PTC) is the most common subtype of thyroid cancer and a highly curable malignancy [1]. However, despite its excellent prognosis, cervical lymph node metastases (CLNMs) are present in a significant percentage of patients with papillary thyroid cancer (PTC) (upto 50% &ndas...

02/17/2021
Research Article

A retrospective cohort study to evaluate the relationship of airway hyperresponsiveness to type 2 biomarkers in persistent asthma

Rory Chan, Chris RuiWen Kuo and Brian Lipworth*

Abstract

Airway hyperresponsiveness (AHR) is a hallmark of persistent asthma measured using direct or indirect airway bronchial challenge testing. The purpose of this study is to investigate the putative relationships between type 2 inflammatory biomarkers, airway geometry (FEV1 and F...

02/16/2021
Research Article

COVID-19 New variant and air pollution relationship: how airborne mutagens agent can act on genoma viruses expression: Hypothesis of work

Luisetto M, Naseer Almukthar, Gamal Abdul Hamid, Tarro G, Khaled Edbey, Nili BA, Ghulam Rasool Mashori, Ahmed Yesvi Rafa and Latyshev O Yu

Abstract

Before actual COVID-19 pandemia coronavirus was not so dangerous like now.
In December 2019 - January 2020 in Wuhan first and then in other places this coronavirus was responsible of a first wave of severe pulmonitis responsible of many deaths.

Wuhan and othe...

02/16/2021
Review Article

Living with ‘Long COVID-19’: The long-term complications and sequelae

Vinod Nikhra*

Abstract

Introduction - the perennial pandemic: It is being increasingly realised that the COVID-19 may have become the new reality associated with human existence world over and the mankind may have to live with it for years or even decades. Further, the grievous nature of the diseas...

02/15/2021
Research Article

FITT-CORRECT: Updated dynamic and evidence-based principle of exercise prescription

Shambhu P Adhikari*, Jarugool Tretriluxana, Rubee Dev, Emily Eglitis, Nistha Shrestha and Cheryl Kerfeld

Abstract

Objective: The FITT (Frequency, Intensity, Time, and Type) principle is an effective foundation in EP. However, the CORRECT components; C–Combination of interventions, O–Order of the Interventions, R–Repetitions, R–Rest period between sets and between ...