HSPC Articles

Articles Library

03/31/2020
Editorial

Palliative care approach to oncological patient – Main points

Muhammed Emin Göktepe, Onur Öztürk* and Mustafa Ünal

Dear Editor

According to the World Health Organization definition, palliative care is an approach aimed at increasing the quality of life of patients and their relatives by addressing physical, psychosocial and spiritual needs and treating conditions early, such as pain while they are...

04/30/2020
Research Article

Development of ELISA based detection system against C. botulinum type B

Arti Sharma* and S Ponmariappan

Abstract

Botulism is the disease caused by botulinum neurotoxins. It is produced by an obligate anaerobic bacteria called Clostridium botulinum. There is no immuno-detection system available in the world for the detection of C. botulinum. Secretory proteins of cooked meat media grown ...

03/27/2020
Opinion

Hypothesis about pathogenic action of Sars-COV-2

Marasco Daniela, Del Prete Salvatore* and Sabetta Rosalaura

Abstract

The Hypothesis born on a simple clinical data noted by some Chinese Reserchers during the starting point of epidemic began in the dicember of the 2019, for the novel member of human coronavirus, officially named as SARS‐CoV‐2 (severe acute respiratory syndrome coronavirus...

03/26/2020
Research Article

Neuroanatomical profile of hemineglect in patient’s body image modification

Maurizio Falso* and Eleonora Cattaneo Psy

Abstract

Background: NSU is generally caused by right cerebral hemisphere lesions with a preeminent localization on the frontoparietal lobe.

Aim: To assess the correlation between the typology and the brain lesion site and the consensual con...

03/19/2020
Research Article

Educational strategy to increase knowledge and risk perception about sexually transmitted infection in polytechnic students

Alba Cortes Alfaro* and Damarys Chacón O’farrill

Summary

Introduction: The incidence of STI-HIV/AIDS is on the rise, making adolescents a vulnerable group at risk.

Objective: To increase the knowledge and perception of risk about STI-HIV/AIDS, through Educational Intervention in students o...

03/17/2020
Research Article

A comparative study between ultrasound guided and landmarks guided intraarticular sacroiliac injections in spondyloarthritis patients

Plamen Todorov* and Anastas Batalov

Abstract

Purpose: Sacroiliac joints (SIJ) inflammation and pain is particularly common in patients with Spondyloarthritis. Intraarticular SIJs injections represent a valuable therapeutic option in this condition. In the rheumatological outpatient clinics this procedur...

03/17/2020
Review Article

Fetal Alcohol Spectrum Disorders – What does it mean?

Rajeev Gupta*

Prenatal alcohol exposure is one of the most important causes of preventable cognitive impairment in the world. The developing neurological system is exquisitely sensitive to harm from alcohol and there is now also substantial evidence that alcohol-related harm can extend...

03/18/2020
Short Communication

Trends in Teledentistry

Rudrakshi C*

Abstract

Socioeconomic barriers appears to be the greatest threat to dental care apart from considering the geographic location of the population. Access to need of care becomes primary consideration and through teleconsultation it is possible to overcome these barriers. As oral cavit...

03/13/2020
Mini Review

Progress of chemical components and biological activities of Fructus Amomi

Yuchen Xiao, Olagoke Zacchaeus Olatunde, Jianping Yong* and Canzhong Lu*

Abstract

Fructus Amomi is “one of the top four south authentic Traditional Chinese Plant Medicines”, widely distributed in tropical and subtropical districts of China, such as Fujian, Guangdong, Guangxi, Hainan, etc., which has ever been used in clinical for treatment of t...

03/11/2020
Research Article

Mesoscopic irreversible thermodynamics of morphological evolution kinetics of helical conformation in bioproteins ‘DNA’ under the isothermal isobaric conditions

Tarik Omer Ogurtani* and Ersin Emre Oren

Abstract

The morphological evolution kinetics and instabilities of alpha helical peptide 3.613, which involves large amount of stored torsional elastic deformation energy (3-40 eV/molecule), is formulated by the variational method based on the connection between the rates of internal ...

03/10/2020
Short Review

“Syndrome of Contractures and Deformities” according Prof. Hans Mau. Symptoms, diagnosis, treatment: Recommendations for parents

Tomasz Karski* and Jacek Karski

Abstract

In development of movement apparatus in small children, youth and – if not cured – in adults play the role two factors. First is connected with small disorders in brain – and in Pediatrics Orthopedic Departments we see very often children with the symptoms o...

03/25/2020
Review Article

Dapt Review

Ujuanbi AS*, Onyeka CA, Yeibake WS, Oremodu T, Kunle-Olowu OE and Otaigbe BE

Abstract

Dual antiplatelet therapy (DAPT) combining aspirin and a P2Y12 receptor inhibitor has been consistently shown to reduce recurrent major adverse cardiovascular events (MACE) in patients with acute coronary syndrome (ACS) or undergoing percutaneous coronary intervention (PCI) f...

03/25/2020
Research Article

A study on pacemaker pocket infection

Goutam Datta*

Abstract

Dual antiplatelet therapy (DAPT) combining aspirin and a P2Y12 receptor inhibitor has been consistently shown to reduce recurrent major adverse cardiovascular events (MACE) in patients with acute coronary syndrome (ACS) or undergoing percutaneous coronary intervention (PCI) f...

03/06/2020
Research Article

Clinical relevance linked to echocardiography diagnosis in Bland, White and Garland syndrome

Mariela Céspedes Almira*, Adel Eladio González Morejón, Giselle Serrano Ricardo and Tania Rosa González Rodríguez

Abstract

Introduction: Bland, White and Garland syndrome is a coronary anomaly with high mortality without treatment. Its clinical presentation is varied which makes epidemiological documentation difficult. Echocardiography is a useful non-invasive tool for diagnosis.

03/03/2020
Case Report

Pathological left ventricular hypertrophy and outflow tract obstruction in an infant of a diabetic mother: A case report

Ujuanbi AS*, Onyeka CA, Yeibake WS, Oremodu T, Kunle-Olowu OE and Otaigbe BE

Abstract

Background: Infants of diabetic mothers (IDMs) are at increased risk of developing congenital anomalies including cardiac defects. Pathological left ventricular hypertrophy, asymmetrical septal hypertrophy and outflow tract obstruction is a rare but known cardi...

03/03/2020
Review Article

His bundle pacing in heart failure: A review of current literature

Rahul Chaudhary* and Jalaj Garg

Abstract

Biventricular (BiV) pacing revolutionized the heart failure management in patients with sinus rhythm and left bundle branch block; however, left ventricular-lead placement is not always technically possible. Also, BiV pacing does not fully normalize ventricular activation and...

03/10/2020
Research Article

Therapeutic application of herbal essential oil and its bioactive compounds as complementary and alternative medicine in cardiovascular-associated diseases

Ahmad Firdaus B Lajis* and Noor Hanis Ismail

Abstract

Background: Herbal essential oil contains pharmacological benefits for intervention treatment of various diseases. Studies have demonstrated its antimicrobial, antioxidant, and anti-inflammatory effect involving in vitro cell culture and preclinical animal mode...

03/27/2020
Research Article

ECHO…for a change!!

Manish Motwani*, Rajeev Palvia, Bhavesh Nanda, Mahek Motwani, Bhakti Chaubal, Jyoti Kesarkar, Bhakti Mange and Sneha Shukla

Introduction

The childhood obesity is increased more than three folds in last two decades in developed world. There is nutritional transition seen in the developing world including India. The westernization in diet of the Indian population along with prosperity brings the brunt of ove...

03/18/2020
Case Report

Epstein-Barr infection causing toxic epidermal necrolysis, hemophagocytic lymphohistiocytosis and cerebritis in a pediatric patient

Aikaterini Solomou, Vasileios Patriarcheas, Pantelis Kraniotis and Andreas Eliades

Abstract

Toxic epidermal necrolysis -the most serious variant of Steven Johnson Syndrome -arises as the result of cell-mediated cytotoxic reaction against keratinocytes. Most common inciting factors include drugs, and infections. On the other hand, Hemophagocytic lymphohistiocytosis (...

03/16/2020
Case Report

Giant prolactinoma case with side effects due to cabergoline

Semiha Çalkaya*, Fahri Bayram, Ali Kurtsoy and Hüseyin Dursun

Abstract

Dopamine agonists should usually be the first treatment for patients with prolactinomas of all sizes, because these drugs decrease serum prolactin concentrations and decrease the size of most lactotroph adenomas. Cabergoline is preferred first. When cabergoline develops side ...

03/04/2020
Case Report

Zoon’s Vulvitis: A case report

S Murphy and A Das

Background

Zoon’s vulvitis or plasma cell vulvitis (PCV) is a rare, benign inflammatory condition of the vulvar mucosa [1].  PCV can present with an asymptomatic lesion, or can cause discomfort, dyspareunia and pruritus [2]. In this way, PCV can mimic other lesions of the v...

03/20/2020
Review Article

Artificial Intelligence in the healthcare of older people

Elizabeta B Mukaetova-Ladinska*, Tracy Harwood and John Maltby

Abstract

Clinical applications of Artificial Intelligence (AI) in healthcare are relatively rare. The high expectations in relation to data analysis influencing general healthcare have not materialized, with few exceptions, and then predominantly in the field of rare diseases, oncolog...

03/10/2020
Review Article

Bioactive components of tea

Gargi Sen*, Nilanjan Sarkar, Moutusi Nath and Subhasis Maity

Abstract

Tea (Black tea and Green tea) are one of the most widely consumed beverages in the world. However, with the increasing interest in the health properties of tea and a significant rise in scientific investigation, this review covers some of the recent findings on the health ben...

03/19/2020
Review Article

Vegetables associated with reduced risk of cancer

Robert Skopec*

Abstract

The present study aimed to investigate and identify the association between the intake of allium vegetables and colorectal cancer (CRC) in population. A hospital‐based matched case‐control study was conducted between June 2009 and November 2011 in three hospitals. Eight h...

03/09/2020
Research Article

A quantum mechanical model for hole transport through DNA: predicting conditions for oscillatory/non-oscillatory behavior

ATM Golam Sarwar, M Rezwan Khan and Arshad Khan*

Abstract

A quantum mechanical model that considers tunneling and inelastic scattering has been applied to explain the hole transfer reaction from a G (Guanine) base to a GGG base cluster through a barrier of Adenine bases, (A)n (n = 1-16). For n = 1, the ratio of tun...

03/05/2020
Review Article

Do genes matter in sleep?-A comprehensive update

Rajib Dutta*

Abstract

Sleep is considered as a complex process in human beings and is least understood mechanism. Role of sleep in synaptic plasticity remains a debatable topic till date. Sleep is influenced by genetic background of the individual. EEG done in human sleep showed strong influence o...

03/09/2020
Research Article

Non-force electromagnetic fields

VV Aksenov*

Introduction

The non-force magnetic fields were first predicted by Chandrasekhar in 1956 in his well-known published work [1]. Since then there have appeared a large number of theoretical studies [5,6,15,17] with the research into various aspects of physical manifestations of non-forc...

03/12/2020
Research Article

Using correlative microscopy for studying and treatment of Mycoplasma infections of the ophtalmic mucosa

Del Prete Salvatore*, Marasco Daniela, De Gennaro Roberto and Del Prete Antonio

Abstract

Purpose: We have studied in 18-month 21 patients showing kerato-conjunctivitis and/or dermato-blefaritis, where we will find a constant presence of mycoplasma in SEM optical cytology samples. The 21 patients were divided as follows: 7 allergic, 7 alleged alle...

03/12/2020
Research Article

Prevalence of premarital sexual practice and associated factors among Goba town high school students, South East-Ethiopia

Shemsu Nuriye Hagisso* and Tilahun Beyene Handiso

Abstract

Background: Premarital sexual practice significantly attributes for increase adolescent’s risk of unintended pregnancy, early marriage, abortion and STIs. In Ethiopia adolescents were intended to engage at early initiation to sexual intercourse without ...

03/10/2020
Review Article

So-called idiopathic scoliosis – disfiguring deformity in children, pain problems in adults. Information about biomechanical etiology, classification and therapy

Tomasz Karski*

Abstract

In the article presented the etiology of the so-called idiopathic scoliosis (Adolescent Idiopathic Scoliosis [AIS]), new classification, there are given rules of therapy and causal prophylaxis. This knowledge is based on observations from 1984, but essentially from the years ...

03/09/2020
Research Article

Impact of Christian meditation and biofeedback on the mental health of graduate students in seminary: A pilot study

Paul Ratanasiripong* and Sun Tsai

Abstract

With increasing awareness of the mental health issues among the clergy and seminary students, it is important to explore possible interventions to help address their mental health concerns. This pilot study examined the impact of Christian meditation and biofeedback on levels...

03/05/2020
Research Article

The different levels of depression and anxiety among Pakistani professionals

Sehrish Hassan* and Waqar Husain

Abstract

The present study was conducted to examine the relationship between work-stress, depression and anxiety among six major professionals (doctors, engineers, bankers, nurses, teachers, and lawyers). The inquiry included 260 professionals from different private and governmental s...

03/05/2020
Research Article

Dairy cattle producers’ perception on Oestrus Synchronization and mass artificial insemination services in Waliso and Ilu Districts of South West Shoa Zone of Oromia, Ethiopia

Abera Fekata*, Ulfina Galmessa, Lemma Fita, Chala Merera and Amanuel Bekuma

Abstract

The study was conducted in Ilu and Waliso districs of South West Shoa Zone to investigate the perception of dairy cattle producers on oestrus synchronization and mass artificial insemination services. A total of 122 respondents (38 from Ilu and 84 from Waliso districts) ownin...

03/04/2020
Research Article

Anatomical changes of the development of red Sokoto goat stomach

Bello A*, Joseph OA, Onua JE, Onyeanusib BI, Umaru MA and Bodinga HA

03/03/2020
Research Article

Common reproductive problem associated with one humped camel (Camelus dromedarius) in West Africa

Bello A* and Bodinga HA

03/02/2020
Mini Review

Depression as a civilization-deformed adaptation and defence mechanism

Bohdan Wasilewski*, Olha Yourtsenyuk and Eugene Egan

Abstract

Depression is currently one of the main barriers to further civilizational development. Despite intensive efforts, it is a growing health, social and economic problem. We still lack clarity regarding the ethology of depression and treatment is still mainly symptomatic. The au...

02/28/2020
Review Article

Transference and countertransference are linked to placebo-nocebo effects and they are an auxiliary resource of unparalleled value in general medicine: Recommendations for general practitioners

Jose Luis Turabian*

Abstract

Psychological phenomena of the doctor-patient relationship influence the therapeutic process. Among these phenomena are the transference (the emotions of the patient towards the doctor), and the countertransference (the emotional reactions of the doctor towards the patient). ...

02/28/2020
Research Article

Analysis of factors influencing participation of farm households in watermelon production in some selected local government areas of Sokoto State, Nigeria

Salihu Abdullahi Abubakar*, Binta Muhammed Manga, Maryam Bello Ali, Abdullahi Muazu and Dalha Magaji

Abstract

The study analyzed the factors influencing participation of farm households’ in watermelon production in the study areas. Three local government areas out of Sokoto state were purposively selected. Questionnaire was used to collect data. Multistage of sampling technique...

02/28/2020
Review Article

Pseudoephedrine protects mice from infection of H1N1 virus

Li Deng, Chengzhi Chu, Xiaoyin Chen* and Zhongping Wu*

Abstract

Ephedra, an ancient herb, is applied to treat common cold and influenza for such a long time in China. Pseudoephedrine is a main active ingredient from Ephedra which is used for relieving nasal congestion clinically. We previously reported that pseudoephedrine showed a potent...

02/28/2020
Case Report

A case of Pulmonary Tuberculosis complicated by Pulmonary Thromboembolism

Jiawen Wang, Changwu Wan, Yuanhe Wang, Mingjie Li, Le Chen and Wang Jie*

Abstract

We report a case of pulmonary embolism complicated with pulmonary tuberculosis. A 48-year-old woman suffered from pulmonary tuberculosis more than 6 years without formal treatment. Recently, she went to hospital because of “chest tightness and dyspnea”, and died i...

02/27/2020
Editorial

Autologous hematopoietic stem cell transplantation in systemic sclerosis patients

Eleftherios Pelechas* and Panagiota Karagianni

Editorial

Systemic sclerosis (SScl) is an autoimmune disorder of unknown aetiology, characterised by fibrosis and microvascular injury of the affected organs. The hallmark of the disease is thickening and tightness of the skin and the subcutaneous tissue. SScl can affect virtually any...

02/28/2020
Review Article

Type 2 diabetes and cancer

Snobia Munir* and Samreen Riaz

Abstract

Diabetes mellitus increases the possibility of different cancers. Scientists have substantiated the link of diabetes with increased prevalence, augmented progression and improved cancer aggression. Research has strengthened link of diabetes with the colorectal cancer risk amo...

02/27/2020
Research Article

Production and evaluation of enzyme-modified lighvan cheese using different levels of commercial enzymes

Mohammad B Habibi Najafi* and Mohammad Amin Miri

Abstract

Enzyme-modified cheeses are concentrated cheese flavors produced enzymatically from dairy substrates in order to provide an intense source of cheese flavor with broad applications. Lighvan cheese is an Iranian traditional cheese with a pleasant taste and flavor generated afte...

02/26/2020
Research Article

In silico discovery of potential inhibitors against Dipeptidyl Peptidase-4: A major biological target of Type-2 diabetes mellitus

Andleeb Subhani, Nadia Arif, Waqar Hussain and Nouman Rasool*

Abstract

Objectives: Type-2 diabetes mellitus, caused by impaired secretion of insulin, is becoming one of the health hazardous threats to human lives across the world. Its prevalence is rising with time. In this study, 2750 phytochemicals, that are considered to have...

02/27/2020
Case Report

Management of temporomandibudar joint ankylosis with costo-chondral graft application: Case report and review of literature

Nikolaos Kolomvos*, Agamemnon Chliaoutakis and Nikolaos Papadogeorgakis

Abstract

Introduction: Temporomandibular joint (TMJ) ankylosis is one of the most disruptive anomaly that affects the masticatory system and is referred as permanent movement disfunction of the mandible caused by bilateral or unilateral fibrous or bony adhesions and c...

02/27/2020
Case Report

Symptomatic cluster-like headache in Normal-Pressure Hydrocephalus (NPH) and possible arteritis: Case report and an overview of the literature on secondary cluster-like headaches

Stefania Peruzzo and Carlo Lovati*

Background

Cluster headache (CH) is a primary headache belonging to the group of trigeminal-autonomic cephalalgias, characterized by short attacks of very severe headache, always involving the same side of the head, more frequently localized to the periorbital and temporal area, assoc...

02/25/2020
Research Article

Translation, adaptation and validation of Depression, Anxiety and Stress Scale in Urdu

Waqar Husain* and Amir Gulzar

Abstract

The current study was carried out to translate, adapt and validate Depression, Anxiety and Stress Scale in Urdu language and in Pakistani culture. The current translation was aimed to produce a more user friendly and clinically applied version of DASS. The systematic procedur...

02/26/2020
Case Report

Acrometastasis as first sign of adenocarcinoma of the lung

Zuhat URAKCI*, Senar EBİNC, Mehmet KUCUKONER, Suat MORKUZU, Ozge YAMAN COSKUN, Zeynep ORUC, Yasin SEZGİN, Erkan BİLEN, Ogur KARHAN, Nadiye AKDENİZ, Muhammet Ali KAPLAN and Abdurrahman ISIKDOGAN

Abstract

Lung cancer is a major cause of morbidity and mortality worldwide. Metastasis can be seen in many organs in advanced-stage disease. Acral metastasis rate in cancer is quite low. However, because of the direct opening of the arterial circulation, the risk of acral metastasis s...

02/25/2020
Editorial

Convalescent plasma: a valid option in the treatment of COVID-19?

Genjiao Liu and Shuang Li*

In the late of 2019, there is an outbreak of novel coronavirus disease (COVID-19) in Wuhan, China. The patients appear respiratory symptoms, fever, and cough, shortness of breath and breathing difficulties. In more severe cases, infection can cause pneumonia, severe acute respiratory syndrome, ki...

02/21/2020
Research Article

Leprosy persistence in the health district of Kenieba despite its elimination as a public health problem at the national level in Mali

Yaya Ibrahim Coulibaly, Ilo Dicko*, Modibo Keita, Housseini Dolo, Modibo Sangaré, Abdoulaye Fomba, Mamoudou Kodio, Nouhou Diarra, Mamadou Sidibé, Oumar Maiga, Moussa Brema Sangaré, Siaka Yamoussa Coulibaly, Michel Emmanuel Coulibaly, Mamadou Dolo, Sory Ibrahima Fomba, Abdallah Amadou Diallo, Floribert Fossuo Thotchum, Ousmane Faye and Samba Ousmane Sow

Abstract

WHO defined leprosy elimination as reaching a prevalence < 1 case of leprosy per 10,000 inhabitants. Mali eliminated the disease since 2001 but in 2011, it recorded 226 new cases. This has a serious involvement in term of disease spreading. Therefore, we undertook a cross ...

02/19/2020
Short Communication

Raw materials criticalities in material selection & design

Paolo Ferro*

Abstract

Circular Economy, Sustainability, Design for Environment are some of the keywords that identify new formidable challenges to be faced in the next years. Raw materials have a dominant role in reaching that goal. Green energy, electric vehicles, communication, etc. depends on r...

02/25/2020
Research Article

Two different patterns and outcome of neodymium YAG capsulotomy

Sudeep Navule Siddappa*, Darshan Shivaura Mahalingu, Rakesha Anjenappa and Tintu Susan Joy

Introduction

Visual impairment is a global health problem. Cataract is responsible for 50% of blindness worldwide [1].

Posterior capsular opacification is the most common late complication of cataract surgery as a result of proliferation of residual lens epithelial cells ove...

02/19/2020
Research Article

Retinopathy of prematurity - Intersibling divergence of risk factors among twins

Sudeep Navule Siddappa*, Kavitha Chikknayakanahalli Venugopal, Pavana Acharya and Tintu Susan Joy

Introduction

Retinopathy of prematurity (ROP) is a consequence of an arrest in normal retinal neural and vascular development, which determines the aberrant retinal regeneration [1,2].

ROP is a disease process mostly reported in preterm neonates ranging from mild, transient ...

02/19/2020
Review Article

The Importance of Potato virus Y Potyvirus

Mahmoud Hamdy Abd El-Aziz*

Abstract

Potato virus Y potyvirus (PVY) is one of the most important aphid transmitted viral pathogen of potato worldwide. PVY affects potato plant (Solanum tuberosum L.), which is an important economic crop. PVY infection with potato viruses usually causing severe economic damage aff...

02/25/2020
Research Article

A retrospective study for Colorectal Cancer in Vlore, Albania-suggestions for further implications

Fatjona Kamberi* and Jerina Jaho

Abstract

Objective: Colorectal cancer is one of the most commonly occurring cancers in men and women worldwide as well as one of the most common causes of death from cancer. It has a higher prevalence in men than women. The treatment of colorectal cancer (surgically o...

02/18/2020
Review Article

ECG interpretation and commentary

Samir Rafla*, Ahmed Mokhtar and Amr Kamal

Abstract

This is demonstration of selected ECGs for learning or for exams; guided by lessons from great teachers as Prof. Hein Wellens MD. Here we provide advanced examples with comment and analysis.

02/18/2020
Review Article

Localization of the occluded vessel in acute myocardial infarction

Samir Rafla* and Amr Kamal

Abstract

This is a review of features in ECG to diagnose the culprit artery responsible for the infarction. Localization of the occluded vessel in acute myocardial infarction is important for many reasons: to know which artery is to dilate and stent; to assess the severity of the lesi...

02/18/2020
Clinical Image

An unusual case of a maxillary sinonasal neuroendocrine carcinoma

Touimi SH*, Daoudi S, Mbarki I, Adrif I, Elkacemi H, Elmajjaoui S, Kebdani T, Errihani H and Benjaafar N

Abstract

It’s a 24 years old female patient who presented with rhinological burning pain evolving since 1 year. She didn’t consult until a blistering lesion filled half of the oral cavity. The initial biopsy of the tumor was interpreted as a round cell tumor process.

02/14/2020
Research Article

Peptide-based antifouling aptasensor for cardiac troponin I detection by surface plasmon resonance applied in medium sized Myocardial Infarction

Jia Xin Che, Yi Wu, Shwu Jen Chang, Ching-Jung Chen* and Jen-Tsai Liu*

Abstract

Highly selective and sensitive detection of cardiac troponin I (cTnI) is a powerful complement to clinical diagnosis of acute myocardial infarction (AMI). In this study, a strategy for cTnI detection was developed by constructing a universal biosensing interface composed of z...

02/18/2020
Research Article

Molecular profiles of hepatotoxicity and nephrotoxicity markers in dysmenorrheic (on treatment or not) students

Ongbayokolak N Sylvie, Djeudong Geraldo, Bilim B Joseph and Telefo Phelix Bruno*

Abstract

Background: Dysmenorrhea is menstrual disorder that affects about 40% - 90% of women worldwide, it is associated with oxidative stress. The current treatment of this condition is administration of non-steroidal anti-inflammatory drugs, which when frequently u...

02/13/2020
Research Article

Anal cytology in immunocompetent patients with high-grade intraepithelial neoplasia (CIN II and CIN III)

Marcio Erik Franco Ribeiro*, Lyliana Coutinho Resende Barbosa and Taylor Brandão Schnaider

Abstract

Introduction: Anal cancer is directly related to the presence of high-grade HPV. Immunocompromised patients have defined conducts, something which is not observed in immunocompetent patients.

Objective: To study the anal cytology of...

02/12/2020
Research Article

Sensitivity and Intertextile variance of amylase paper for saliva detection

Alexander Lotozynski*

Summary

Contemporary forensic science hinges on DNA analysis to link an individual to a crime scene. Sources of DNA include bodily fluids, including saliva. Amylase is a primary enzyme in human saliva and thus, if detected, indicates possible presence of human saliva. Amylase paper ca...

02/11/2020
Research Article

Improving cancer diseases classification using a hybrid filter and wrapper feature subset selection

Noor Muhammed Noori* and Omar Saber Qasim

Abstract

In the classification of cancer data sets, we note that they contain a number of additional features that influence the classification accuracy. There are many evolutionary algorithms that are used to define the feature and reduce dimensional patterns such as the gray wolf al...

02/20/2020
Research Article

Sexual addiction, self-esteem and personality dimensions

Badii Amamou*, Cyrine Missaoui, Amjed Ben Haouala, Ahmad Mhalla, Ferid Zaafrane and Lotfi Gaha

Abstract

Sexual addiction is a growing reality. The acknowledgment of this disorder requires to identify vulnerability factors. Besides, it would improve the management and treatment of these people. We used a cross-sectional study with a sample of voluntary subjects recruited online ...

02/11/2020
Research Article

Assessment of physicians’ knowledge, attitudes, and practices regarding smoking cessation management in the Gaza Strip

Khaled Hani Alkhodari*, Bakr Khadr Abo Jarad, Ahmed Ismail Al-Bahbhani, Sadi Yehia Nkhala, Ali Naim Al-Buhisi and Khamis Abdelkarim Elessi

Abstract

Background: Despite its negative effects, approximately 23% of Palestinians (≥ 18 years) smoke cigarettes. Studies have shown physicians to be an important channel for smoking cessation intervention. This investigation examines physicians’ smoking-re...

02/24/2020
Research Article

Benign Paroxysmal Positional Vertigo (BPPV) and microvasculitis: A comparative study between nasal cytology and pathology

Armone Caruso Arturo*, Del Prete Salvatore*, Marasco Daniela, Veronica Viola, Sabato Leo, Andrea Fulgione, Daniele Naviglio and Monica Gallo

Abstract

Purpose: Benign paroxysmal positional vertigo (BPPV) is the most frequent peripheral vertigo syndrome in otoneurological clinical practice and is characterized by short and paroxysmal objective vertigo crises caused by changes in the position of the head on s...

02/18/2020
Short Review

Chlorhexidine and oral cancer: A short review

Shrivardhan R Kalghatgi*, Mahesh R Khairnar and Tanushri Dalvi

Owing to the ever westernizing lifestyles in developing countries like India, the escalation of oral cancer patients are in need of urgent plan of action. With tobacco being the commonest cause for causation of oral cancer, Global Adult Tobacco Survey, 2016-17 revealed that almost 28% of whole po...

02/17/2020
Mini Review

Angiotensin II type 1 receptor and the activation of Myosin Light-Chain Kinase and Protein Kinase C-βII: Mini Review

Gerry A Smith*

Summary

The involvement of the angiotensin II type 1 receptor in the Frank-Starling Law of the Heart, where the various activations are very limited, allows simple analysis of the kinase systems involved and thence extrapolation of the mechanism to that of angiotensin control of activ...

02/06/2020
Case Report

Delayed penile prosthesis implantation in the delayed presentation of ischemic priapism

IRZI Mohamed*, MHANNA Tarik, EL HOUMAIDI Amine, Mohammed Aynaou, Mehdi Chennoufi, OURAGHI Abdelghani, ALAOUI MHAMMEDI Wassim and Ali Barki

Abstract

Priapism is currently defined as a prolonged painful erection without sexual stimuli, if priapism persists > 36 hours, conservative treatment does not lead to detumescence.
The most common etiologies are: medications into corpora cavernosa, anti-psychotics, anti-hyp...

02/06/2020
Research Article

In vitro and preventative field evaluations of potential biological control agents and synthetic fungicides for control of Clarireedia jacksonii sp. nov.

Jeffery W Marvin, Robert A Kerr*, Lambert B McCarty, William C Bridges, S Bruce Martin and Christina E Wells

Abstract

Clarireedia jacksonii sp. nov. Formerly Sclerotinia homoeocarpa F.T. Bennett, the causal agent of dollar spot (DS), is the most destructive pathogen in turfgrass. Symptoms appear as circular patches 10-40 mm in diameter with small tan lesions surrounded by a darker band, some...

02/05/2020
Research Article

Heterotopic Gastric Mucosa of the Proximal Esophagus: An Under recognized Entity

Sarhani Asmae*, Paupard Thierry, Ghani Sara, Salihoun Mouna and Kabbaj Nawal

Abstract

Heterotopic gastric mucosa (HGM) is an islet of gastric mucosa within the esophageal mucosa. These lesions can sit throughout the digestive tract and rarely in the upper third of the esophagus. The pathophysiology of HGM remains poorly understood.

Our study aims to ...

02/04/2020
Review Article

Rubella infection: Advances and challenges in the diagnosis and prevention of Congenital Rubella Syndrome

Amelia Nkutxi Vueba* and Maria do Ceu Sousa

Abstract

Rubella remains an important pathogen worldwide, with many cases of congenital rubella syndrome per year. Rubella vaccination is included in the vaccination program of many countries. WHO has set goals for the elimination of measles and rubella and prevention of congenital ru...

02/04/2020
Research Article

Medicinal plant extract associated with bacterial cellulose membrane: Antibacterial activity and physicochemical properties

Fernando Batain, Kessi Crescencio, Thais Alves, Juliana Ferreira Souza, Venâncio Amaral, Juliana Castro, Carolina Santos, Angela Jozala, Luciane Lopes* and Marco Chaud*

Abstract

Burns injuries induce a state of immunodepression that predisposes to a bacterial infectious complication that leads to several comorbid diseases and high mortality rate. Previous studies about anti-inflammatory, antimicrobial and antioxidant properties of Aloe vera (L.) Burm...

02/05/2020
Research Article

Case-based education to improve learning and faculty teaching of residents and students in a clinical setting

Elizabeth A Wetzel and Diane E Lorant*

Abstract

Introduction: Current pediatric residents spend less time in the neonatal intensive care unit (NICU) and as a result, resident exposure to neonatal pathophysiology has decreased. Engaging learners efficiently while balancing clinical demands is challenging. P...

01/31/2020
Research Article

Gender-specific associations of anthropometric measures of adiposity with blood pressure and hypertension in young Chinese Medical College Students

Navin Kumar Sah†, Qing-Tao Zhang†, Yong-Gang Li, Xue-Yan Yin and Li-Hua Li*

Abstract

Purpose: There are uncertainties about whether general or central obesity is the more important determinant for blood pressure and hypertension in young Chinese. We aim to investigate the association between adiposity measures and blood pressure and hypertens...

01/30/2020
Research Article

Low sensitivity of the careHPV™ Assay for detection of Oncogenic Human Papillomavirus in cervical samples from HIV-infected and HIV-uninfected Kenyan women

Titus M, Ermel A, Moormann A, Cu-Uvin S, Orang’o O, Tonui P, Chelimo K, Rosen B, Itsura P, Muthoka K, Loehrer P, Ong’echa JM and Brown DR*

Abstract

Background: Human papillomavirus (HPV) infection causes cervical cancer (CC), a common malignancy among Kenyan women. New CC screening methods rely on oncogenic HPV (“high-risk”, or HR-HPV) detection, but most have not been evaluated in swabs from...

01/29/2020
Research Article

Demographic pattern of refractive anomalies in Niger Delta presbyopes - Implications for preventive eye care practice

Ireju Onyinye Chukwuka* and Chinyere Nnenne Pedro-Egbe

Abstract

Background/Aim: In spite of global initiatives to provide sight for all by the year 2020, many middle-aged to elderly people in the Niger Delta still have significant visual impairment due to uncorrected refractive errors. The aim of this study is to assess t...

01/31/2020
Research Article

Aripiprazole-induced seizures in children with autism spectrum disorder and epilepsy

Mohammed MS Jan*

Abstract

Purpose: Children with autism spectrum disorder are at an increased risk for developing seizures, which can be triggered by classical antipsychotics. Aripiprazole is an atypical antipsychotic that has a safer drug profile. The objective is to present the expe...

01/29/2020
Research Article

Current childhood cancer survivor long-term follow-up practices in South Africa

Anel van Zyl*, Paul C Rogers and Mariana Kruger

Summary

Background: The number of childhood cancer survivors (CCSs) is increasing due to improved survival. Most suffer at least one treatment-related late effect, even decades after treatment, thus lifelong long-term follow-up (LTFU) care is a necessity. Currently no...

01/28/2020
Research Article

Lateral Pancreato-Jejunostomy in Chronic Pancreatitis: An appraisal of 32 cases

Sardar Rezaul Islam*, Shafiqur Rahman, Shaurav Talukdar, Shah Alam Sarkar, Shah Poran and Mushfiqur Rahman

Abstract

Background: Lateral Pancreaticojejunostomy (LPJ) has recognized applications in the management of Chronic Pancreatitis (CP). It is done for patients with severe pain, obstructed and dilated pancreatic duct. Ductal obstruction by stone or stricture causes rise...

01/30/2020
Review Article

Classification of diseases using a hybrid fuzzy mutual information technique with binary bat algorithm

Firas Ahmed Yonis AL-Taie* and Omar Saber Qasim

Abstract

Genetic datasets have a large number of features that may significantly affect the disease classification process, especially datasets related to cancer diseases. Evolutionary algorithms (EA) are used to find the fastest and best way to perform these calculations, such as the...

01/24/2020
Review Article

Brain washing systems and other circulating factors in some neurological condition like Parkinson (Pd) and vascular and diabetic dementia: How dynamics- saturation of clearance can act on toxic molecule?

Mauro Luisetto*, Farhan Ahmad Khan, Akram Muhamad, Ghulam Rasool Mashori, Behzad Nili Ahmadabadi and Oleg Yurevich Latiyshev

Abstract

Observing the epidemiology of some neurodegenerative disease is interesting to verify some similarity and also related advanced or non-advanced countries and related diet habits. There are relationship between this conditions and diet habits? Some neurological condition relat...

01/31/2020
Editorial

Biological markers of oxidative stress in exhaled air

Chrsitian Sarbach and Eric Postaire*

Editorial

Oxidation reactions produce, through complex intermediate steps, small energy packages that are more easily stored than a sudden combustion oxidation. The slow and controlled production of energy in a nuclear power plant allows its use, a massive explosion produces the resul...

01/22/2020
Research Article

Antiuropathogenic and antioxidant activities of Hypoxis hemerocallidea Lam. extracts, and compounds from its taxonomically related species

Kokoette Bassey* and Sekelwa Cosa

Abstract

Hypoxis hemerocallidea Lam is one of the 43 Hypoxis species in South Africa, marketed extensively as over the counter herbal product for the management of several diseases. The plant commercial products link efficacy to hypoxoside 4, its aglycone (rooperol), or β-sitoste...

01/20/2020
Case Report

Granulomatosis with polyangiitis (GPA) in a 76-year old woman presenting with pulmonary nodule and accelerating acute kidney injury

Noor Sameh Darwich, Melissa Schnell and L. Nicholas Cossey

Abstract

Granulomatosis with polyangiitis (GPA), a form of ANCA-associated vasculitis (AAV), is a rare disease with an often-occult presentation. It is more common in 4th and 5th decades of life but can be seen in all ages.

This case report details a 76-year-old female prese...

01/14/2020
Research Article

Uterine precursor lesions in patients with incidental nodal lymphangioleiomyomatosis: A report of 4 cases

Charles M Lombard*

Abstract

Uterine sections from 6 patients with incidental nodal lymphangioleiomyomatosis (LAM) were examined for LAM lesions by screening these sections with cathepsin K immunohistochemistry (IHC) stains. The hysterectomy specimens were all concurrent with the lymph node dissections i...

01/13/2020
Review Article

The Neppe-Close triadic dimensional vortical paradigm: An invited summary

Vernon M Neppe* and Edward R Close

Abstract

Physicists are generally trained in the Standard Model of Physics (SMP). This implies that they perceive and account for only 3 dimensions of space in a moment in time (3S-1t) (a 4-dimensional [4D] model). However, applying the SMP, more than fifty significant conundrums have...

01/13/2020
Case Report

Occluded superior vena cava and failed epicardial pacing: An unorthodox solution

Ranjit K Nath* and Satyam Rajvanshi

Abstract

Permanent pacemaker implantation is conventionally done via upper limb veins. But in 1% - 6% cases, usual sub clavicular approach is either not possible or contraindicated due to complete occlusion of superior vena cava (SVC) or bilateral subclavian vein and/or bilateral impl...

01/13/2020
Case Report

Coronary-intercostal steal syndrome, a rare connection between the left circumflex coronary artery and intercostal arteries: A case report

Mohammed H Habib and Khaled H Alkhodari*

Abstract

A 60-year-old female patient presented with typical anginal pain on exertion and relieved by rest for about one month. Percutaneous coronary angiography was done and showed an abnormal left circumflex coronary artery connecting to intercostal artery. Embolization of that abno...

01/10/2020
Editorial

Retrosternal goiter mimicking asthma: A diagnostic challenge

Yiannakopoulou Eugenia*

Editorial

Asthma is a chronic respiratory disease characterized by chronic airway inflammation. Common manifestations of asthma include wheezing, chest tightness, cough, shortness of breath. Diagnosis of asthma requires clinical documentation of respiratory symptoms, exacerbation of s...

01/10/2020
Research Article

Oral Clindamycin and Metronidazole in the treatment of bacterial vaginosis in pregnant black women: Comparison of efficacy and pregnancy outcome

Ijeoma CC*, Nyengidiki TK, Bassey G, Ogu RN, Alegbeleye JO and Wariso KT

Abstract

Bacterial vaginosis (BV) is associated with adverse pregnancy outcomes with various treatment options.

Objective: To compare the efficacy and effect on pregnancy outcome of Metronidazole and Clindamycin in women with bacterial vaginosis in Port Harc...

12/31/2019
Opinion

Obesity-Treatment by drugs

Sahithi G*

Opinion

The main disturbing situation faced by any individual is obesity nowadays. Obesity occurs because of overweight and this has several reasons to gain weight like hereditary, diabetes, diet, aging, PCOS in women, stress, and tiredness. It is a major, sustaining, worsening condit...

01/09/2020
Research Article

An evaluation of hardness of commercially available provisional restorative materials: An in vitro study

Nimra Mehraj, Samarth Kumar Agarwal*, Romil Singhal and Kanesha Abrol

Abstract

Statement of problem: Provisional restorations play a critical role in the success of restorative treatment so they must maintain their integrity in the oral environment throughout the diagnostic and restorative phases.

Purpose: The...

01/09/2020
Research Article

Effect of hemodialysis session on acute changes in inflammatory and cardiovascular risk biomarkers

Bernardo-Alio Lavin Gomez*, Maria-Teresa García Unzueta, Armando-Raul Guerra Ruiz, Sonia Perez San-Martin, Ana Berja, Natalia Fananas Rodriguez, Sara Diez Espejo and Domingo Gonzalez-Lamuno Leguina

Abstract

Background: Inflammation is associated with enhanced cardiovascular risk profile and increased cardiovascular mortality in end-stage kidney disease patients undergoing hemodialysis. Mechanisms of activated acute phase reaction in patients on chronic hemodialy...

01/08/2020
Review Article

A proposed mechanism to explain increases in intracranial pressure: The concept of cerebral artery wedge pressure

DR Hamilton*, A Mitha, MG Hamilton and JV Tyberg

Abstract

We hypothesize that, with elevated cerebral spinal fluid (CSF) pressure, cerebral micro-vascular obstruction and congestion may occur despite (subdural) large-vein pressures being normal. Smaller veins emptying into these larger, dura-enveloped veins are not immune to the com...

12/31/2019
Research Article

The importance of gestational age in first trimester, maternal urine MALDI-Tof MS screening tests for Down Syndrome

Ray K Iles*, Nicolaides K, Pais RJ, Zmuidinaite R, Keshavarz S, Poon LCY and Butler SA

Abstract

Background: The proposal that MALDI-ToF mass spectrometry could be used as a direct, rapid and affordable diagnostic tool in clinical laboratory medicine has moved from a theoretical possibility to a reality for Microbiology. Several studies have proposed the...

12/31/2019
Research Article

Burden of hearing loss in Subsaharan Africa: Snapshot from an ENT clinic in Nigeria

Ogunkeyede SA*, Adebola SO, Daniel A and Adeyemo AA

Summary

Background: Disabling hearing loss is a prevalent public health issue, with significant impact on patients’ communication. The disability associated with hearing loss depends on the severity of the hearing loss. There are limited rehabilitative measures ...

01/06/2020
Case Report

A case study on Erdheim ‐ Chester Disease

Jakob Erdheim and Harald Koeck*

Abstract

In this brief essay, Harald Koeck offers an introduction to Professor Jakob Erdheim, an eminent pathologist of Vienna. Koeck is an independent researcher at different Pathology Departments (Department of Pathology St. Poelten with Prof. Hans Bank MD, Department of Pathology M...

12/17/2019
Clinical Image

A rare case of abdominal pain and hematuria from retroaortic left renal vein

Perez J* and Pozo D

Clinical Image

A 62-year-old female with a history of arterial hypertension, attended the emergency department due to pain in the left flank. On physical examination no showed signs of peritoneal irritation. Urinalysis was indicated, that reported microscopic hematuria and negative ab...

12/30/2019
Research Article

Potential of Pleurotus sajor-caju compost for controlling Meloidogyne incognita and improve nutritional status of tomato plants

Doaa M Mostafa, Sherin FA Awd Allah* and Eman FA Awad-Allah

Abstract

The potential of spent compost of oyster mushroom, Pleurotus sajor-caju cultivated on rice (MCR) or wheat straws (MCW) was evaluated against the root-knot nematode, Meloidogyne incognita on tomato plants under field conditions during two successive seasons (2016 and 2017). Th...

12/30/2019
Research Article

Evaluation of the effect of coronary artery bypass grafting on the right ventricular function using speckle tracking echocardiography

Mahmoud Shawky Abdelmoneum, Neama Ali Elmeligy, Elsayed Abdelkhalek Eldarky and Mohamad Mahmoud Mohamad*

Abstract

Purpose: This was a prospective study conducted at Benha University hospital and National Heart Institute on one hundred patients undwent coronary artery bypass grafting (CABG) to evaluate the effect of CABG on the right ventricular (RV) function using speckl...

12/30/2019
Case Report

Parry-Romberg syndrome: A case report of non-invasive treatment

Anahita Dehghani Soltani, Azita Tehranchi, Shiva Safari, Zahra Tehrani and Samin Ghaffari*

Abstract

Parry-Romberg syndrome is an uncommon condition, self-limiting with slow progressive hemifacial atrophy. This syndrome can lead to several progressive congenital and developmental deformities. It can cause severe facial asymmetry and subsequently lead to esthetic and psycholo...

12/27/2019
Research Article

Nutritional analysis of Sphenostylis Stenocarpa seeds partially included with soya bean meal in Heterobranchus Bidorsalis fingerling diet

Oluwaseyi Yanmife Mogaji*, Lenient Mercy Onivie Ibiyo and Felicia Oluwatoyin Joshua

Abstract

Five experimental feeding trials were conducted to investigate the performance of Heterobranchus bidorsalis fingerlings to graded levels (0, 25, 50,75 and 100%) of Sphenostylis stenocarpa seed meal diets. Complete randomized design with triplicate groups of fingerlings was us...

12/27/2019
Research Article

Beginnings of bariatric and metabolic surgery in Spain

Aniceto Baltasar*

Overview

Bariatric Surgery (BS) from the Greek bari = weight and iatrein = cure) treats obesity and began in Spain in 1973. Its greatest development occurs after the founding of SECO (Spanish Society of Obesity Surgery) in 1997. The purpose of this work is to reflect the changes that ...

12/24/2019
Research Article

The effect of a European-based exercise program upon the health-related physical fitness of individuals with intellectual disabilities: The alive and kicking perspective

Skordilis Emmanouil*, Greenlees Iain, Chrysagis Nikolaos, Grammatopoulou Eirini, Arriaga Andres, Vaquero Fernandez Almudena, Gaillard Joel, Skordilis Antonios, Dias Joao, Papadopoulou Vassiliki and Serras Dionysios

Abstract

The present study examined the effect of the European-Based ‘Alive and Kicking’ exercise program on the health-related physical fitness of individuals with (Experimental Group: EG) and without (Control Group: CG) (Intellectual Disability: ID). The Self-Determinati...

12/24/2019
Research Article

Pregnancy and childbirth in women aged 40 and over at befelatanana maternity, Madagascar

Rakotomalala Nivoarimelina Zoly*, Rakotozanany Besaina, Razafindraibe Andriatompoina Felanarivo, Ramarokoto Malalafinaritra Patrick Marco, Rafamatanantsoa Jean Florent, Kapche Wato Edith and Randriambololona Domoina Malala Aurelia

Abstract

Objective: Pregnancy after age 40 remains a concern as it exposes to particular obstetrical complications. Our study aims to determine the risks of complications related to pregnancy and childbirth of women aged 40 and over.

Study design:

12/23/2019
Case Report

Orgasmic coitus triggered stillbirth via placental abruption: A case report

Márta Zsoldos, Márton Vezér, Henriette Pusztafalvi, Bianka Pencz, Dora Hargitai and Attila Pajor*

Summary

Sexual activity during healthy pregnancy is safe. There are little data on how coital activity affects outcome of the high-risk pregnancies. Hereby we report a case demonstrating that orgasmic coitus triggered placental abruption resulting in preterm stillbirth.

A 38...

12/31/2019
Research Article

Synthesis of Carbon Nano Fiber from Organic Waste and Activation of its Surface Area

Brijesh Gaud, Amrita Singh, Sandesh Jaybhaye and Himanshu Narayan*

Abstract

Carbon Nano fibers (CNFs) have recently attracted a lot of attention due to their widespread range of technological applications attributed to their unique physical and chemical properties, such as, small size, high strength, high adsorption linked with their large specific s...

12/18/2019
Mini Review

Could metabolic risk factors contribute to the development of cervical cancer?

Maydelín Frontela-Noda*, Eduardo Cabrera-Rode, Maite Hernández-Menéndez and Raquel Duran-Bornot

Abstract

The role of human papillomavirus infection as etiological factor for cervical squamous intraepithelial lesions and cervical cancer is well established. However, the presence of this virus is not sufficient condition for developing of cervical cancer. Currently, the contributi...

12/23/2019
Research Article

Snake envenomation during pregnancy

Denisse Martínez and Newton G Osborne*

Abstract

Background: We report our experience with management and treatment of pregnant women who were admitted at our institution for snake envenomation.

Methods: We reviewed the charts and recorded the management, treatment, and outcome of...

12/19/2019
Research Article

Theoretical study on binding interactions of laccase-enzyme from Ganoderma weberianum with multiples ligand substrates with environmental impact

Yosberto Cárdenas-Moreno*, Luis Ariel Espinosa, Julio Cesar Vieyto, Michael González-Durruthy, Alberto del Monte-Martinez, Gilda Guerra-Rivera and Maria Isabel Sánchez López

Abstract

Laccase catalyzes oxidation of lignin and aromatic compound with similar structure to this one. Their low substrate specificity results on degradation of similar phenolic compounds. In this context, Molecular Docking was performed with different ligands suggesting potential b...

12/18/2019
Review Article

A review on the occurrence of opportunistic infections after applications of stem cell techniques

Hasan Hosainzadegan*, Parviz Vahedi and Mortaza Hosainzadegan

Abstract

In recent years, stem cells technology have been used widely in basic and clinical science researches LIPUS (low-intensity pulsed ultrasound) is another technique commonly used in conjunction with stem cells that can have complications after applications. One of the important...

12/17/2019
Research Article

Comparative effect of calcium supplementation on the incidence of pre-eclampsia and eclampsia among primigravid women

Assontsa Kafack Carole*, Essiben Felix, Tumasang Florence, Meka Esther Juliette, Tongo Sedrick Fofack and Mbu Robinson Enow

Abstract

Background: Pre-eclampsia is a frequent and serious pregnancy complication contributing for the increasing maternal morbi-mortality rates. This study was designed to evaluate the effect of calcium supplementation during pregnancy, on the incidence of pre-ecla...

12/17/2019
Clinical Image

Cytomegalovirus infection in native kidney biopsy

Raquel M Moreira, Géssica SB Barbosa*, Cristiane B Dias, Luis Yu, Viktoria Woronik and Lívia B Cavalcante

Text

A 61-year-old Brazilian black woman consulted with a nephrologist due to proteinuria identified on a routine urine test. She has a personal history of thymoma resection five years ago, followed by multiple episodes of pulmonary infections including mycobacteriosis, recurrent muco...

12/12/2019
Research Article

Nematicidal effect of abamectin, boron, chitosan, hydrogen peroxide and Bacillus thuringiensis against citrus nematode on Valencia orange trees

MAM El-Saedy, Sandy E Hammad and Sherin FA Awd Allah*

Abstract

The nematicidal efficacy of abamectin, boron, chitosan, hydrogen peroxide, Bacillus thuringiensis and oxamyl 24% SL against citrus nematode, Tylenchulus semipenetrans were examined on Valencia orange trees under field condition for two successive seasons (2017 and 2018). The ...

12/12/2019
Research Article

Dry eye syndrome: Therapeutic challenges and future trends

Irami Araújo-Neto, Amália Cinhtia Meneses Rêgo and Irami Araújo-Filho*

Abstract

Introduction: Intense Pulsed Light (IPL) is the therapeutic tool implemented in the treatment of dry eye, characterized by the emission of waves of 500-1200nm in the region of the upper and lower eyelids. Dry eye is a recurring complaint in ophthalmology offi...

12/11/2019
Letter to the Editor

Evaluation in real life of the impact of photo-protection counseling in patients with actinic keratosis

Khaled Ezzedine, Sophie Seité and Charles Taïeb*

Dear Editor

Actinic keratosis (AK) are scaly lesions caused by chronic ultraviolet-induced damage to the epidermis which are a proxy for excessive sun-exposure [1] that may evolve into squamous cell carcinoma [2-7]. Therefore,&nbs...

12/05/2019
Case Report

Localized intrapulmonary desmoplastic mesothelioma: A case report

Meng Liu, Kaifu Wu and Yongming Tan*

Abstract

Introduction: Desmoplastic Malignant Mesothelioma (DMM) is a rare histological subtype of sarcomatoid malignant mesothelioma arising most frequently in the pleura or peritoneum and less frequently in the lung parenchyma.

Patient concerns:

12/06/2019
Letter to the Editor

Achievement of cure following allogeneic HSCT with Flu-Bu regimen in a patient with severe mycosis fungoides and Sezary Syndrome

Mahmut Yeral*

Letter to Editor

Experience with allogeneic hematopoietic stem cell transplantation (HSCT) in mycosis fungoides/Sezary syndrome (MF/SS) is limited to a small number of case reports and case series [1,2]. The advantage of allogeneic HSCT has been indicated in progressive dise...

12/09/2019
Research Article

A pilot study on treatment of infantile cystinosis with mesenchymal stem cells

Faysal Gok*, Cengiz Zeybek, Ayse Balat and Olcay Y Jones

Abstract

Infantile cystinosis is a lysosomal storage disease leading to end stage kidney disease at early ages. There is no effective treatment and patients require long term dialysis or kidney transplant for survival. We present our experience on three affected children who received ...

12/05/2019
Research Article

Aggressive hydration in early resuscitation phase does not provide mortality benefit in acute pancreatitis

Abu Omar Y*, Wang Y, Agrawal R, Randhawa T, Majeed M, Attar BM, Demetria MV and Simons-Linares CR

Abstract

Introduction: Fluid management is the cornerstone of treatment for acute pancreatitis (AP), but the proper rate and volume is still controversial. We aim to evaluate the role of aggressive hydration in AP patients.

Methods: We retro...

12/05/2019
Research Article

The motivational factors and adverse events experienced by healthy volunteers donating bone marrow for research

Mirella Ejiugwo, Georgina Shaw, Frank Barry, Janusz Krawczyk and Veronica McInerney*

Abstract

Background: With the advancement of cell therapy research, there is an increasing need for healthy volunteers (HV) to donate small volumes (30 ml) of human bone marrow (BM). The BM procedure required to procure small volumes is invasive, although short-lived ...

12/16/2019
Case Report

Aortic dissection causing 2 myocardial infarctions

Sebastian Szabo and Hans Martin Hoffmeister

Abstract

A 56-year-old man was admitted to our hospital because of sudden onset of right-sided thoracic pain. The ECG showed inferior ST segment elevations. He has been treated with aspirin, clopidogrel, unfractionated heparin and tenecteplase, and his symptoms resolved after 30 minut...

12/11/2019
Research Article

Co-extract mixture from Strophanthus hispidus (roots) and Aframomum meleguta (seeds) show phytochemical synergy in its anti-inflammatory activity

John Kenneth Mensah*, Amina Ibrahim and Yakubu Jibira

Abstract

Background: Combination of extracts from multiple plants are typically used in ethnomedicine to putatively offer more potent chemotherapeutic and chemopreventive effects than that of individual extracts from single plants. Aqueous extracts from two multipurpo...

12/10/2019
Research Article

To legalize cannabis in Ghana or not to legalize? Reviewing the pharmacological evidence

Kwesi Boadu Mensah* and Paa Kofi Tawiah Adu-Gyamfi

Summary

Background: Although illegal, Ghana has a long history of cannabis use. With changing perceptions, advocacy for legalization has increased globally. This study exams pharmacological evidence on the prospects and challenges of decriminalization and /or legaliza...

12/11/2019
Review Article

Risk factor of liver metastases in breast cancer

Akram Yazdani*

Abstract

Objective: The liver is the second most common site of distant metastases from breast cancer. We investigated the risk factor liver metastasis in patients with breast cancer.

Methods: We studied Age, Menopausal status, Histologic Ty...

12/10/2019
Review Article

Different optimization strategies for the optimal control of tumor growth

Sweilam NH, Tharwat AA and Abd El Moniem NK*

Abstract

In this article different numerical techniques for solving optimal control problems is introduced, the aim of this paper is to achieve the best accuracy for the Optimal Control Problem (OCP) which has the objective of minimizing the size of tumor cells by the end of the treat...

12/12/2019
Case Report

Embolic Septic Emboli with MRSA: A different source

Christian Castillo Latorre*, Mariela Rivera Agosto, Ilean Lamboy Hernandez, Mariana Mercader Perez, Dominic Sanchez Paredes, Marisol Santiago Irizarry, Jose Gutierrez Nuñez Onix, Cantres Fonseca, Alfonso Torres Palacios and William Rodriguez Cintron

Abstract

Septic Iliac vein thrombophlebitis with associated psoas abscess is a rare and severe entity, which diagnosis is challenging when no risk factor is clearly present. We are presenting a case of severe septic cavitary pulmonary emboli complicated with Acute Respiratory Distress...

12/09/2019
Case Report

Brainstem Death due to hypertension induced brain hemorrhage

Satyajit Patra* and Sreeraj Suresh

Introduction

Brain stem death is when a person has permanently lost the potential for consciousness and the capacity to breathe. When this happens, a machine called a ventilator keeps oxygen circulating through the person’s bloodstream - a person confirmed as being dead when the...

12/12/2019
Research Article

Postgraduate students’ perception of the educational environment of a wet lab training in Neurological Surgery Division, UCH, Ibadan

Malomo Adefolarin O*, Kafayat Bolaji Aminu, Adeolu Augustine A, Adeleye Amos O, Balogun James A, Badejo Oluwakemi A, Shokunbi Mathew T and Jegede Ayodele S

Summary

Objective: The importance of understanding the perceptions of medical students to their training environment cannot be overemphasized. The study evaluated the wet lab training organized for Senior Registrars in the Neurosurgery, Division of the University Coll...

12/05/2019
Research Article

Health care workers knowledge, attitude and practice towards hospital acquired infection prevention at Dessie referral hospital, Northeast Ethiopia

Hailemariam Gezie, Emebet Leta, Fikrte Admasu, Sisay Gedamu*, Abebe Dires and Debrnesh Goshiye

Abstract

Introduction: Contact of health care workers and patient at health facility lead to the transmission of pathogenic organisms to each other. Hospital acquired infection prevention is standardized guide lines contain multitude protocols needed to be implemented...

12/03/2019
Letter to the Editor

Effect evaluation of vitamin D level amongst patients with chronic hepatitis B

Freshteh Osmani*

Text

Vitamin D has immunomodulatory and antifibrotic properties, and therefore used for treatment of many of chronic liver disease [1]. Although there are many reports on the relationship between serum 25-hydroxyvitamin D3 levels and chronic liver diseases, but the relationship betwee...

12/16/2019
Case Report

Intracerebral Hemorrhage of Brainstem in triple pregnancy after in vitro fertilization by receiving Ovum Donation: A case report and review

Andreas Suhartoyo Winarno*, Lukas Schloesser, Frederic Dietzel, Percy Balan, Thomas Hoehn, Monika Hampl and Tanja Natascha Fehm

Abstract

Deliveries prior to 28 weeks’ gestation (extreme preterm birth) pose a global health concern, according to the World Health Organization (WHO). Extreme preterm birth is associated with several complications in the newborn and management in neonatal intensive care unit w...

12/11/2019
Research Article

The influence of opioid on the microstructural organization of the Wall OT the uterus of the white laboratory rat

Mateshuk-Vatseba LR, Ivankiv Ya T and Ivankiv TM*

Introduction

Drug addiction is one of the burning problems in the modern society. Annually there is a steady increase in the level of drug abuse. United Nations Office on Drugs and Crime publishes “World Drugs Report 2018”, where it was reported that about 275 million peop...

12/04/2019
Research Article

Bio-moleculear thermal oscillator and constant heat current source

R Panahinia* and S Behnia

Abstract

The demand for materials and devices that are capable of controlling heat flux has attracted many interests due to desire to attain new sources of energy and on-chip cooling. Excellent properties of DNA make it as an interesting nanomaterial in future technologies. In this pa...

12/09/2019
Review Article

Natural killer cells in patients with hematologic malignancies, solid tumors and in recipients of hematopoietic stem cell transplantation

Al-Anazi KA*, Al-Jasser AM and Al-Anazi WK

Abstract

Natural killer cells represent the first line of defense against infections and tumors and can be derived from various sources including: bone marrow, peripheral blood, specific types of human stem cells, and certain cell lines. The functions of natural killer cells are influ...

12/06/2019
Case Report

Scraping cytology and scanning electron microscopy in diagnosis and therapy of corneal ulcer by mycobacterium infection

Del Prete Salvatore, Marasco Daniela1, Del Prete Antonio, Meloni Marisa, Capaldi Roberto, Grumetto Lucia and Russo Giacomo*

Purpose: This work is aimed at demonstrating that scraping cytology and scanning electron microscopy can successfully assist in the diagnosis of nontuberculous mycobacteria infection. For this purpose, we report the use of both these techniques in the diagnosis of cornel ulcer in...

12/06/2019
Case Report

Meckel Gruber Syndrome: A rare and lethal anomaly

Zana Zegarac*, Zeljko Duic and Katarina Bojanic

Case Report

We wish to present our case of the rare Meckel-Gruber syndrome, diagnosed prenatally at 18 weeks’ gestation. Informed consent was obtained from both parents for publishing this case and including photos.

12/03/2019
Research Article

Previous antibiotic treatment as a risk factor for recurrent vulvovaginal candidiasis

Wen Yang#, You Nie#, Shujuan Wang, Hongwei Wang, Enfeng Zhao and Na Dou*

Abstract

The incidence of recurrent vulvovaginal candidiasis (RVVC) is extremely high. RVVC is likely to have a greater impact on patients. The aim of the study was to explore the risk factors of recurrent vulvovaginal candidiasis (RVVC) in the tropical coastal area. In this case-cont...

12/02/2019
Review Article

Microchimerism may be the cause of psychiatric disorders

Bulent Demirbek and Osman Demirhan*

Introduction

Microchimerism is a bidirectional exchange of fetal and maternal cells during pregnancy (Figure 1). Pregnancy is the most common and natural cause of chimerism, and bi-directional trafficking of hematopoietic cells occurs through the placenta. Therefore, we are all born a...

11/29/2019
Clinical Image

Branchio Oculo Facial Syndrome

Maha Oudrhiri*, Toualouth L, Houda Oubejja, Fouad Ettayebi and Hicham Zerhouni

Clinical Image

A 3-month-old girl presented to the surgical consultation room with bilateral cleft lip incomplete. A girl weighing 4205 g, was born at term  after an uneventful pregnancy with a birth weight of 2500 g. There was no family history. On examination, a congenital, lin...

11/29/2019
Research Article

Patients’ satisfaction and associated factors towards nursing care in Dessie Referral Hospital, Northeast Ethiopia

Afework Edmealem*, Yabebal Asfaw, Sewunet Ademe and Belachew Tegegne

Abstract

Introduction: A patient satisfaction is considered as one of the desire outcomes of health care and it is directly related with utilization of health services. However, its level is falls at the fundamental level in developing countries including Ethiopia.

11/27/2019
Short Communication

Modeling of A.I based Inhalation for Advanced Life Support System Development

Md. Sadique Shaikh* and Tanvir Begum

Abstract

Present piece of idea exhibits to divert attention towards automated high precision Life Support System (LSS) instead of manual one using medical intelligence devices while treating and diagnosis to the patient, where Ventilator, inhaler and respiratory control is most import...

11/27/2019
Research Article

Biodegradation of gold and platinum implants in rats studied by electron microscopy

Hendrik Kosslick, Hermann Sauer, Tino Just, Ursula Vick, Gerhard Fulda and Ludwig Jonas*

Abstract

Biodegradation of implanted gold in human tissue. TEM images reveal markedly biodegradation of implanted gold and re-crystallization of dissolved gold as nanoparticle of different size, shape and crystallinity. Highly crystalline icosahedral Au nanoparticle and the correspond...

11/27/2019
Research Article

Gaucher’s disease and liver involvement: A review and our experience

Vitantonio Guglielmi*, Mario Correale and Gioacchino Leandro

Abstract

Background: This article reviews current knowledge of Gaucher’s disease (GD) and liver involvement and reports our experience: how many patients with chronic liver disease of unknown origin could be affected by Gaucher’s disease.

11/27/2019
Research Article

Innovative results in the treatment of inespecific anusitis-proctitis with the use of bergamot gel (Benebeo gel)®

Danilo Cafaro, Felipe Celedon, Alessandro Sturiale and Stefania Sinicropi*

Introduction

Inflammation is a complex biological reaction induced by the alteration of tissue homeostasis, which occurs in response to the presence of a biological, chemical or physical agent in the body [1]. The acute inflammatory response is composed of an elaborate cascade of both...

11/26/2019
Prospective

Recent approach to incorporate tellurium in metal carbonyl cluster utilizing extrusion reaction

Pradeep Mathur* and Ajeet Singh*

Abstract

The incorporation of tellurium into metal carbonyl using tellurium transfer/ extrusion reaction is presented in this work. The results bring one of the new ways to incorporate tellurium by transferring it from one molecule to another molecule, in comparison to the work so far...

11/26/2019
Research Article

Long-Term Impact of Coronary Artery Disease in Lung Transplantation

William S Ragalie, Nilto C de Oliveira, Richard Cornwell, Keith Meyer and James D Maloney*

Background: Adoption of the Lung Allocation Score (LAS) has led to increased listing of older patients and those with idiopathic pulmonary fibrosis (IPF) for lung transplantation (LTX). Older patients and those with IPF have higher prevalence of coronary artery disease (CAD), a r...

11/26/2019
Research Article

Readjustment of antithrombotic therapy in stroke-patients owing to transesophageal echocardiography findings

Toralf Bruening* and Mohamed Al-Khaled

Objectives: Cardioembolic etiology is a frequent source of ischemic stroke. Echocardiogram is the mainstay of cardioembolic source detection with regard to plan secondary stroke management, however it remains unclear how often clinically actionable findings are provided hereby. I...

11/25/2019
Case Report

Resolved complete atrioventricular block and left ventricular severe dysfunction in patient with Wegener’s granulomatis after cyclophosphamide and corticosteroid treatment

Duc Dang*, Lory Trevisan, Jérôme Bouet and Jérôme Taieb

Introduction

Wegener’s granulomatosis is a systemic granulomatous focus on small to medium sized vessels. It typically affects sinuses, lungs and kidneys due to necrotizing granulomatous vasculitis. Less commonly, cardiac involvement is reported up to 8%-44% of cases [1-3]. It o...

11/20/2019
Research Article

The Renin-Angiotensin System: Alamandine is reduced in patients with Idiopathic Pulmonary Fibrosis

Taís Salvi Sipriani, Robson Augusto Souza dos Santos and Katya Rigatto*

Abstract

Idiopathic Pulmonary Fibrosis (IPF) is a chronic and progressive disease without treatment that leads to death. Therefore, to control its progression to pulmonary hypertension is still a challenge. Moreover, there is no study that has investigated the Renin-Angiotensin System...

11/22/2019
Research Article

Correlation between the presence of maternal gestational or pre-gestational pathologies and hearing impairment in the puerperal period

Raphaella Costa Moreira Simen*, Alan Araújo Vieira, Maria Elisa Vieira da Cunha Ramos Miterhof and Armanda de Oliveira Pache de Faria

Abstract

Objective: To evaluate whether the occurrence of maternal pathologies, mainly Diabetes Mellitus and Hypertensive Syndromes in the gestational or pre-gestational period may be related to hearing impairment in postpartum women.

Methods:

11/21/2019
Case Report

First trimester growth delay: An early marker of triploidy

Sydney M Thayer*, Rachel A Pilliod, Emmanuelle Pare, Amber Vandehey, Hannah Raszka, Kelly Thomas and Rinathia Hachmon

Introduction

Triploidy is one the most common chromosomal abnormality in humans, complicating about 1% of all human pregnancies. Most affected conceptions undergo spontaneous abortion in the first trimester, making the prevalence of second trimester triploidy low. Viable triploidy is ...

11/25/2019
Case Report

Lateral Pedicle and Connective Tissue Graft – A combined approach for management of isolated gingival recession

Ramnath Elangovan*, Ramakrishnan Theyagarajan, Ebenezer Mani and Mejalla Muthiah Amaladhas

Abstract

Gingival recession is defined as apical migration of the gingival epithelium leading to the exposure of root surface. There are many surgical procedures for treating gingival recessions and the main goal is to cover the exposed tooth surface by soft tissue augmentation. The s...

11/21/2019
Case Report

Cranio-Facial Fibrous Dysplasia: A case report of a conservative treatment in a monostotic form associated with an orthodontic management and a bone graft of the non-lytic bone area for dental implant rehabilitation

Seban A*, Blein E, Perez S and Seban B

Abstract

Fibrous dysplasia is an osteolytic lesion in which bone is replaced by an instable fibrous osseous tissue. The aim of this case report is to highlight dental rehabilitation (bone grafts to allow dental implant) on patients suffering of this condition.

A 39-year-old ...

11/27/2019
Research Article

Perceived causes and prevention of catheter-associated urinary tract infections among spinal cord injured patients

Malomo Adefolarin O*, Aminu, Kafayat, Adeolu Augustine A, Adeleye Amos O, Balogun James A, Badejo Oluwakemi A, Shokunbi Mathew T and Jegede Ayodele S

Summary

Catheter-associated urinary tract infection (CAUTI) is among the most common nosocomial infections especially in acute care settings. Its economic and unanticipated health implications make it burdensome for the healthcare providers and patients. The paper examined the perceiv...

11/22/2019
Research Article

Effect of intradialytic physical activity on the quality of life, biological parameters and sleep in hemodialysis patients

Mélanie Gallot, Nathalie Rieth and Alexandre Ganea

Abstract

Many side effects, in addition to those of the pathology itself, have occurred with hemodialysis treatment but existing literature have shown that physical activity is beneficial to hemodialysis patients. Nevertheless, our parameters have not been studied enough with a resist...

11/20/2019
Case Report

Diabetes and chronic kidney disease: a rare cause for a very common association

José Agapito Fonseca*, Sofia Jorge, Joana Gameiro, José António Lopes and José Oliveira Guerra

Abstract

The authors present the case of a 45-year-old female patient with diabetes and chronic kidney disease (CKD). She had unsatisfactory glycemic control, and showed some intellectual limitations. Her urine exam was unremarkable, and her renal ultrasound revealed single right kidn...

11/20/2019
Research Article

Acute Appendicitis: Hispanics and the Hamburger Sign

Garcia Gubern C, Colon Rolón L, Ruiz Mercado I, Oliveras Garcia C, Caban Acosta D, Muñoz Pagán J, Iriarte I, Bolaños Ávila G Peguero Rivera J, Sánchez Gaetan F, Oneill Castro J, Cordero Colón Paola N, Garcia-Colon Carlos A and Romero-Vazquez Ana M*

Abstract

Objective: To describe the presenting clinical findings of patients with acute appendicitis and compare them with those described in the medical literature. To corroborate a common medical myth among Hispanic physicians regarding the presentation of acute app...

11/20/2019
Letter to the Editor

Hot cholecystectomy

Esam Aboutaleb*

Letter to Editor

Acute cholecystitis is a common general surgery disease which may require hospital admission. Delayed or early cholecystectomy is the definitive treatment. Availability of theatre slots may postpone cholecystectomy for weeks. I am writing this letter to explain the im...

11/20/2019
Research Article

Only low intensity of aerobic exercise improves respiratory compliance in pulmonary hypertensive rats

Katya Rigatto*, Denielli Da SG Bós, Renata Fernandes, Rodrigo B Jaenisch and Pedro Dal Lago

Abstract

Objective: To investigate in an animal model of Pulmonary Hypertension (PH) by monocrotaline whether a lower exercise intensity, which has lower potential to provoke dyspnea symptoms, could prevent the increase the right ventricle pressure and the decrease in...

11/20/2019
Case Report

Foley catheter balloon tamponade as a method of controlling iatrogenic pulmonary artery bleeding in redo thoracic surgery

Marcus Taylor*, Muhammad Asghar Nawaz, Ozhin Karadakhy, Denish Apparau, Kandadai Rammohan and Paul Waterworth

Background: Pulmonary artery bleeding secondary to iatrogenic injury is a troublesome intraoperative complication. The likelihood of encountering this complication is significantly higher in redo surgery for a number of reasons, including distortion of anatomical structures, a...

11/20/2019
Case Report

Treatment of autoimmune hemolytic anemia with erythropoietin: A case report

Juan P Ovalle, Estefanía M Orozco, Laura C Pedraza, María C Barrera, Renato A Guzmán* and Dormar D Barrios M

In this article, we describe the case of a fifty-year-old patient with autoimmune hemolytic anemia (AIHA) with constitutional symptoms, jaundice, unquantified fever and progressive dyspnea. The patient had history of smoking and Hepatitis A and following a physical exam she was found in a regu...

11/19/2019
Case Report

Patellar fractures in children

Mohammed Shabeer*, Nasir Muzaffar and Sameh Abdalla

We describe a rare case of patellar fracture in a seven year old girl. The case was reviewed for various aspects such as clinical diagnosis, imaging tests and most suitable treatment.

11/11/2019
Research Article

Immunohistochemical expression of Nestin as Cancer Stem Cell Marker in gliomas

Rasha Mokhtar Abdelkareem*, Afaf T Elnashar, Khaled Nasser Fadle and Eman MS Muhammad

Abstract

Background: Gliomas represent the most frequent primary tumors of central nervous system (CNS), contributing to more than half of the incidence of brain tumors. Cancer stem cell markers (CSC) identify a group of patients at high risk for progression. Nestin i...

11/13/2019
Research Article

Evaluation of outcomes of 8-week therapy with ledipasvir/sofosbuvir or glecaprevir/pibrentasvir in veterans with hepatitis C infection

L Anri Lemoine and Marisel Segarra-Newnham*

Summary

Hepatitis C Virus (HCV) infection is usually treated with direct acting antivirals (DAAs) for 12 weeks. In treatment naive patients with genotype (GT) 1 infection without cirrhosis and baseline viral load <6 million, 8 weeks of Ledipasvir/Sofosbuvir (LDV/SOF) is an option. ...

11/15/2019
Research Article

Left ventricular ejection fraction and contrast induced acute kidney injury in patients undergoing cardiac catheterization: Results of retrospective chart review

Firas Ajam, Obiora Maludum, Nene Ugoeke, Hetavi Mahida, Anas Alrefaee, Amy Quinlan DNP, Jennifer Heck-Kanellidis NP, Dawn Calderon DO, Mohammad A Hossain* and Arif Asif

Abstract

Background: Contrast-induced acute kidney injury (CI-AKI) is an important cause of increasing the hospital stay and in-hospital mortality. By increasing intra-renal vasoconstriction, left ventricular ejection fraction (LVEF) can increase the risk of CI-AKI. W...

11/15/2019
Case Report

Hemoptysis after subclavian vein puncture for pacemaker implantation: A case report

Avishek Bagchi, Rajendra Kumar Agarwal and Kewal Kishan Talwar*

Abstract

Background: Subclavian venous access for pacemaker lead insertion is a common procedure and is normally considered safe in the hands of an expert. However, subclavian venepuncture is not without complications, starting from mild subcutaneous hematoma to pneum...

11/11/2019
Research Article

Correlation of plasma protein from MDS, young and elderly patients by SDS-page

Nathanielly de Lima Silva, Danilo Nobre, Josiel Nascimento dos Santos, Márcia Santos Rezende, Lúcio Henrique Sousa Pinheiro, Carlos Arthur Cardoso Almeida and Dulce Marta Schimieguel*

Abstract

Summary: Myelodysplastic Syndrome (MDS) is a heterogeneous group of clonal hematopoietic malignancies characterized by progressive cytopenias, ineffective hematopoiesis, bone marrow hypercellularity and transformation to acute myeloid leukemia (AML).

<...

11/12/2019
Opinion

States Care - The Cure for Patient Healthcare

Deane Waldman*

Opinion

Clinical physicians believe they are drowning . . . because they are! Between complying with an ever-changing landscape of time-wasting federal regulations, avoiding Health Insurance Portability and Accountability Act violations, plus the entire billing process, who can keep u...

11/15/2019
Review Article

Alcoholism and its implications for the dental team, an update and review of the literature

Vignesh Eswara Murthy*

Abstract

Precis: This Literature review is intended to provide dental practitioners with an update of the implications that Alcoholism poses to them.

Statement of the problem: Alcoholism raises several distinct problems for dental profession...

11/15/2019
Editorial

Pulse Synchronized Contractions (PSCs)

Katherine A Lothman* and Allen W Mangel

Editorial

A key platform underpinning the traditional understanding of the cardiovascular system, with respect to the behavior of large arterial vessels, is Otto Frank’s Windkessel Hypothesis [1]. This hypothesis posits simply that the smooth muscle walls of large arteries do no...

11/08/2019
Research Article

Incidence of hypertension in a high-risk workgroup (Police officers) - Observational study

Guillermo Padrón Arredondo*

Summary

Introduction: Hypertension is a silent pathology in a way that affects all four spheres to be considered as such; magnitude, transcendence vulnerability, and feasibility. The World Health Organization estimates that 45% of deaths from heart disease and 51% of ...

11/08/2019
Short Communication

Human mesenchymal stem cells conditioned media promotes the wound healing process - An in vitro study

Rashi K Jain*, Devashree Vakil, Corey Cunningham and Kuldip Sidhu

Abstract

Mesenchymal stem cells (MSCs) conditioned medium (CM) has a promising prospect towards skin regeneration. Therefore, human dental pulp and adipose stem cells (DPSCs and ADSCs) were isolated, propagated and evaluated for their stemness and genetic stability over time in cultur...

11/05/2019
Review Article

Drug abuse and its ramifications on skeletal system

Das Sanjita* and Kumar Naveen

Abstract

The purpose of this study is to highlight the drug abuse hazards and preventive aspects. From a public health perspective, substance abuse has long been a source of major concern, both for the individual’s health and for wider society as a whole. The UK has the highest ...

11/01/2019
Opinion

Biological membranes: The laboratory of fundamental physics

Samo Kralj* and Mitja Kralj

Opinion

Biological membranes present an essential constituent of living cells. Their main role is to separate the interior of a cell from its surrounding, however allowing the selective transfer of specific material through it. Configuration changes of membranes are often correlated w...

11/04/2019
Research Article

A Systematic review for sudden cardiac death in hypertrophic cardiomyopathy patients with Myocardial Fibrosis: A CMR LGE Study

Sahadev T Reddy, Antonio T Paladino, Nackle J Silva, Mark Doyle, Diane A Vido and Robert WW Biederman*

Abstract

Background: Hypertrophic cardiomyopathy (HCM) patients have a predisposition for malignant VT/VF and consequently, sudden cardiac death (SCD). In single center studies, late gadolinium enhancement (LGE) defined fibrosis has been linked to VT/VF. However, desp...

11/04/2019
Review Article

Do beta adrenoceptor blocking agents provide the same degree of clinically convincing morbidity and mortality benefits in patients with chronic heart failure? A literature review

Martin Mumuni Danaah Malick*

Abstract

Chronic heart failure has been extensively characterized as a disorder arising from a complex interaction between impaired ventricular performance and neurohormonal activation. Since beta adrenoceptor blocking agents are currently considered an integral component of therapy f...

11/01/2019
Research Article

Anthropometric characteristics and somatotype of professional soccer players by position

Cavia MM*, Moreno A, Fernández-Trabanco B, Carrillo C and Alonso-Torre SR

Abstract

The anthropometric characteristics are decisive for an optimal physical level and, therefore, a good level in the game; and they can be different depending on the game position.

The aim of this study was to identify the physical characteristics, body composition and...

10/31/2019
Research Article

Gynaecological malignancies after breast cancer diagnosis: A population-based study

Maria Pilar Barretina-Ginesta, Jaume Galceran*, Helena Pla, Cristina Meléndez, Anna Carbo Bague, Alberto Ameijide, Marià Carulla, Jordi Barretina, Angel Izquierdo and Rafael Marcos-Gragera

Abstract

Background: Breast cancer (BC) is one of the most prevalent malignancies. BC survivors have higher risk of second primary cancers than the general population. There is an increased interest in BC survivor management, including the prevention of these second c...

10/31/2019
Research Article

Renal function effects of FDS, a saponin isolated from Filicium decipiens seeds: Biochemical and Histopathological studies

Romero MP Brandao-Costa*, Juanize Matias S Batistaa, Thiago Pajeu Nascimento and Ana LF Porto

Abstract

Physicochemical and pharmacological studies indicated that Filicium decipiens seeds contained various specialized metabolites, including saponins. The aim of this work is to reveal the nephrotoxicity of FDS, a saponin isolated from Filicium decipiens seeds on male Wistar rats...

10/28/2019
Case Report

Stercoral perforation: A rare case and review

Lava Krishna Kannappa*, Muhammad Sufian Khalid, May Hnin Lwin Ko, Mohsin Hussein, Jia Hui Choong, Ameer Omar Rawal-Pangarkar, Danaradja Armugam and Yahya Salama

Abstract

We present a 54-year-old male with abdominal pain, Vomiting and weight loss since 5 months. Perforation was noted at recto-sigmoid junction and underwent Hartman’s procedure with end colostomy. Histology of sigmoid colon confirmed a Stercoral perforation without any evi...

11/04/2019
Review Article

Protection from the Pathogenesis of Neurodegenerative Disorders, including Alzheimer’s Disease, Amyotrophic Lateral Sclerosis, Huntington’s Disease, and Parkinson’s Diseases, through the Mitigation of Reactive Oxygen Species

Samskruthi Madireddy* and Sahithi Madireddy

Abstract

The biological changes caused by oxidative stress (OS) are known to be involved in the etiology of neurodegenerative disorders, including Alzheimer’s disease, amyotrophic lateral sclerosis, Huntington’s disease, and Parkinson’s disease. The brain is particul...

11/06/2019
Case Report

A unique case of metastatic spinal epidural abscess associated with liver abscess following ascending cholangitis and Escherichia coli bacteremia

Nour Karra#, Samer Ganam#, Amitai Bickel, Maxim Bez, Ibrahim Abu Shakra, Doron Fischer and Eli Kakiashvili*

Abstract

Pyogenic liver abscess (PLA) is a life-threatening infection that may develop as a result of an underlying hepatobiliary disease. A possible complication of PLA is metastatic spread, resulting in distant seeding of infection in other organs, and occasionally in the epidural s...

11/04/2019
Research Article

Diagnosis of critical congenital heart defects in Iceland 2000-2014

Hallfríður Kristinsdóttir, Þórður Þórkelsson, Hildur Harðardóttir and Gylfi Óskarsson*

Abstract

Critical congenital heart defects (CCHDs) are preferably diagnosed prenatally or soon after birth. Late diagnosis has been related to poorer prognosis. The aim of this study is to assess when CCHDs are diagnosed in Iceland and whether late diagnosis is a problem. All live bor...

10/28/2019
Research Article

Evaluation of the predictive value of CHA2DS2-VASc Score for no-reflow phenomenon in patients with ST-segment elevation myocardial infarction who underwent Primary Percutaneous Coronary Intervention

Mahmoud Shawky Abd El-Moneum*

Abstract

Objective: The aim of this study was to estimate the predictive clinical value of CHA2DS2-VASc score for no-reflow phenomena in patients having ST-segment elevation myocardial infarction (STEMI) who applied to primary percutaneous coronary intervention (PCI)....

10/25/2019
Research Article

Age Estimation Reports: Where do we stand?

Sakher Al Qahtani*

Abstract

Age estimations process is not standardized worldwide. However, there is a wide agreement about the most suitable methods currently available. Up until now, the procedure of creating expert reports and to implement quality assurance in age estimation are variable.

<...

06/05/2019
Research Article

Radiofrequency ablation for snoring and sleep apnoea

Shah Neha*

Aim

Radiofrequency proves to be a useful tool for snoring sleep apnoea cases. Its advantage includes relative precision in incision making, relative bloodless fields if used appropriately, decrease postoperative pain and excellent healing with fibrosis which aids in stiffening tissues...

09/20/2019
Research Article

Addition of Simvastatin to Carvedilol and Endoscopic Variceal Ligation improves rebleeding and survival in patients with Child-Pugh A and B class but not in Child Pugh C class

Sanjeev Kumar Jha*, Kuldeep Saharawat, Ravi Keshari, Praveen Jha, Shubham Purkayastha and Ravish Ranjan

Summary

Background: Even with current standard treatment after variceal bleeding which includes combination of nonselective b-blockers and repeated endoscopic variceal ligation, the risk of rebleeding and mortality are high. Statins exhibit an antifibrotic effect and ...

10/23/2019
Research Article

Compliance of hypertensive patients with antihypertensive drug therapy at the Renaissance Hospital of N’Djamena, Chad

Adam Ahamat Ali*, Guillaume Mahamat Abderraman*, Zeinabou Maiga Moussa Tondi and Hissein Ali Mahamat

Abstract

Introduction: High blood pressure is a major cardiovascular risk factor. In hypertension, non-compliance is frequent. The objective of this work is to evaluate the therapeutic observances and to identify the predictive factors of poor compliances in Chadian h...

10/22/2019
Commentary

We may need to reconsider when to apply sunscreen in our daily life

Win L Chiou*

Abstract

Broad-spectrum sunscreens are now widely used worldwide as an adjunct to help prevent sunburn, skin cancers and premature skin aging. In the United States, all persons older than 6 months are recommended to apply sunscreen to all sun-exposed skin from toes to head except eyes...

10/16/2019
Case Report

Intestinal malrotation presenting with midgut volvulus in an adult

Marta Alberich Prats*, Ricard Frago Montanuy and Sebastiano Biondo Aglio

A 36-year-old man without previous medical history presented to the emergency department with abdominal pain and vomiting of acute onset. His vital signs were stable and he had no fever. Abdominal exploration revealed distention with pain at palpation. Laboratory tests were normal. Abdominal X...

10/18/2019
Case Report

Anterior Abdominal Wall Abscess: An unusual presentation of Carcinoma of the Colon

Keerthana Panchagnula, Poojitha Yalla, Badareesh Lakshminarayana*, Kshama Hegde and Ramesh Singaraddi

Abstract

Background: Colorectal cancer progresses without any symptoms early on, or those clinical symptoms are very discrete and so are undetected for long periods of time. The case reported is an unusual presentation of colorectal cancer.

Case Repo...

10/04/2019
Research Article

Nebulization as complementary therapy for dogs with respiratory tract infections

Stopyra Artur*, Sobiech Przemyslaw, Pomianowski Andrzej, Zarczynska Katarzyna and Edyta Kaczorek

Abstract

Respiratory tract infections in dogs pose a significant problem and often require prolonged treatment. The effectiveness of pharmacological therapy can be improved through the administration of nebulized compounds to liquidize mucus and promote its evacuation from the respira...

10/21/2019
Research Article

Impact of Pacemaker Implantation on 12-Month Resource Utilization Following TAVR Hospitalization

Steven D Culler*, Aaron D Kugelmass, David J Cohen, Matthew R Reynolds, Phillip P Brown, April W Simon and Marc R Katz

Abstract

Purpose: This study reports resource utilization during a Medicare Beneficiary’s (MBs) Transcatheter Aortic Valve Replacement (TAVR) index hospitalization and all subsequent encounters for 12 months and compares data between MBs who did or did not recei...

10/17/2019
Research Article

The effect of anemia on serum hepcidin levels in patients with heart failure

Betul Borku Uysal*, Feray Akbas, Esma Altunoglu, Gulhan Ipek Denız, Duygu Uysal, Harun Uysal, Hanife Usta Atmaca, Yasin Yuksel, Hale Aral, Guven Cetın, Cem Ar M and Fusun Erdenen

Abstract

Background: Anemia is an accelerating problem among patients with heart failure (HF) and its presence is associated with more symptoms. In this study, we investigated whether anemia in heart failure was related to hepcidin concentration.

Met...

10/12/2019
Research Article

Synthesis of NaYF4:Yb,Er@SiO2@Ag core-shell nanoparticles for plasmon-enhanced upconversion luminescence in bio-applications

Grigory Arzumanyan*, Dmitriy Linnik*, Kahramon Mamatkulov, Maria Vorobyeva, Anastasia Korsun, Valentina Glasunova and Anka Jevremovic

Abstract

The present report highlights our results on synthesis of NaYF4:Yb,Er@SiO2@Ag core–shell nanoparticles (CSNPs) for plasmon-enhanced upconversion luminescence (UCL). Hydrophilic surface UCL nanoparticles (UCLNPs) as cores were obtained by precipitation of Rare Earth Elem...

09/26/2019
Research Article

Haemostasis with suture-tourniquet technique following removal of large-bore venous sheaths for endovascular recanalization of acute thrombosis in native arteriovenous fistula

Omur Balli*

Abstract

Purpose: To investigate the suture-tourniquet technique for haemostasis in patients with acute thrombosis of native arteriovenous fistula (AVF) whom underwent manual aspiration thrombectomy using large-bore venous sheaths and high dose heparin.

10/01/2019
Research Article

Tamsulosin and Dementia in old age: Is there any relationship?

Rebecca Renata Lapenda do Monte, Karina de Andrade Vidal Costa, Arnaldo Santiago Nunes Junior, Amalia Cinthia Meneses Rego and Irami Araujo-Filho*

Abstract

Tamsulosin is used to treat Benign Prostatic Hyperplasia (BPH), prescribed annually to about 12.6 million patients worldwide. It is an alpha-adrenergic antagonist that reduces the tone of the prostate smooth muscle involved in the pathophysiology of BPH. By acting on alpha 1A...

10/02/2019
Case Report

Fatal agranulocytosis associated with Metamizole treatment in a 16-year-old girl

Packo Dieu-le-veut Saint-Cyr Sylvestre*, Nanho Danho Clotaire, N’dhatz Comoe Emeraude, Boidy Kouakou, Camengo Police Serge Magloire, Diakite Mamady, Mbelesso Pascal and Koffi Kouassi Gustave

Agranulocytosis is one of the common reasons of consultation in hematology. It’s life-threatening because of an infection risk. The metamizole is a drug, known for its potential rare danger of inducing a severe agranulocytosis. However, it remains widely used because of its beneficial effect...

09/30/2019
Case Report

Automatic heartbeat monitoring system

Franchini Roberto*

The proliferation and popularity of open source hardware and software, such as Arduino and Raspberry PI, together with IoT and Embedded System, has brought the health industry to rapid evolution, creating portable and low-cost medical devices for monitoring vital signals. Electrocardiographic ...

09/24/2019
Case Report

A rare case of recurrent urinary tract infection due to Trichosporon species in an immune-competent diabetic female patient

Saroj Adhikari, Bhuvan Saud*, Govinda Paudel and Sunita Wagle

Trichosporonosis is a disease caused by Trichosporon spp. which are ubiquitous anamorphic yeast that commonly inhabit the soil. In human they are found in the skin, gastrointestinal tract and respiratory tract. Globally, Trichosporon spp. infection is rare and remain...

09/27/2019
Research Article

Screening of antibiotic residue in poultry in Kathmandu valley of Nepal: A cross-sectional study

Rajiv Sapkota*, Ramila Raut, Sujan Khanal, Muna Gyawali and Dipesh Sahi

Abstract

This cross-sectional study was conducted to screen the presence of antibiotic residue in poultry. A total of 60 samples (30 Muscle and 30 Liver) were taken from local meat shops from different parts of Kathmandu valley. Disc assay method was used. Escherichia coli (ATCC 25922...

09/20/2019
Research Article

The association between hypoxia, chronic ischemia and alters prostate structure and progress of chronic prostatic disease

Mauro Luisetto*, Behzad Nili Ahmadabadi, Ghulam Rasool Mashori, Gamal Abdul Hamid

Abstract

Chronic prostatitis today show high level of relapses and recurrent pathological events even if using the best pharmacological therapy. A better understanding of physiopathological effect of ischemic hypoxic condition (pelvic, prostate tissue) and the lymphatic congestion in ...

09/19/2019
Research Article

Prevalence of disabling hearing loss in the elderly

Letícia Raquel Baraky Vasconcelos, Paula Ferraz Rodrigues, Paula Liziero Tavares and Audryo Oliveira Nogueira*

Abstract

Introduction: Disabling hearing loss refers to hearing thresholds superior than 40 dB in the better ear in the adults. The main cause of hearing loss in the elderly is the age-related hearing loss, also called presbycusis. This type of hearing impairment occu...

09/19/2019
Case Report

Occipital lobe ependymal cyst with unusual presentation

Okacha Naama*, Abdelilah Idir and Omar Boulahroud

Abstract

Intraparenchymal cysts without communication to the ventricles or the subarachnoid space are named ependymal or epithelial cysts. The estimated ratio of their incidence compared with arachnoid cysts is 1:10. Neurologic deficit can occur when the cyst exerts mass effect on its...

10/10/2019
Review Article

Three modern serological methods to detect plant viruses

Mahmoud Hamdy Abd El-Aziz*

Abstract

The use of enzyme linked immunosorbent assay (ELISA) for the detection of plant viruses is well documented. It proved to be a very valuable detection tools for the plant viruses. The efficiency of the ELISA technique was for practical purpose independent of the ratio of antib...

10/04/2019
Research Article

Comprehensive phenotypic characterization and genetic distinction of distinct goosegrass (Eleusine indica L. Gaertn.) ecotypes

Robert A Kerr*, Tatyana Zhebentyayeva, Christopher Saski and Lambert B McCarty

Abstract

Goosegrass (Eleusine indica L. Gaertn.) is a troublesome weed in turfgrass systems throughout the world. The development of herbicide resistant ecotypes has occurred to multiple modes of action. Goosegrass is a prolific seed producer (~50,000 per plant), fast growing and dive...

10/01/2019
Research Article

Serological and molecular characterization of two seed born cowpea mosaic Comovirus isolates affecting cowpea plants (Vigna unguiculata L.) in northern Egypt

Mahmoud Hamdy Abd El-Aziz* and Hosny Aly Younes

Abstract

Cowpea plants naturally infected with cowpea mosaic comovirus (CPMV) showed different mosaic, mottle, dwarfing, and vain clearing symptoms. Diseased plants were ollected from certain locations of Alexandria and El-Beheira governorates during the growing seasons from 2011 to 2...

09/13/2019
Review Article

Avermectins: The promising solution to control plant parasitic nematodes

Mohamed S Khalil* and Dalia M Darwesh

Abstract

Abamectin and emamectin are members of avermectin family which categorized as very effective but in the same time are toxic naturally. Most of products in this family are utilized as pharmaceuticals in both humans & animals and for crop protection.Despite avermectins are ...

09/18/2019
Research Article

Low back pain induces disability of women in primary uncomplicated pregnancy

Panagiotis Korovessis*, Rania Antonaki, Spyridon Zacharatos and Vasileios Syrimpeis

Abstract

Study design: A consecutive case series study

Purpose: To investigate whether Low Back Pain (LBP) in women with primary singleton pregnancy induces disability.

Background: LBP is reported to be increased i...

10/01/2019
Editorial

The rising role of natural killer cells in patients with malignant hematological disorders and in recipients of hematopoietic stem cell transplantation

Khalid Ahmed Al-Anazi*

Introduction

Natural killer (NK) cells, the third population of lymphoid cells, comprise 5%-25% of peripheral blood (PB) lymphocytes and represent the first line of defense against infections and tumors [1-7]. They can be derived from: bone marrow, PB, cryopreserved umbilical cord blo...

09/04/2019
Review Article

Advances in the use of GABAergic interneurons for the treatment of epilepsy

Federica Frisina#, Giulia Valetti#, Giulia Zuccarini#, Luciano Conti# and Giorgio R Merlo*

Abstract

Forebrain GABAergic neurons, the main inhibitory type of neuron in the cortex and hippocampus, represent a highly heterogeneous cell population that has been implicated in the predisposition to epilepsy and the onset of seizure. Earlier attempts to restore inhibition and redu...

09/27/2019
Research Article

Glycemic status and its effect in Neonatal Sepsis - A prospective study in a Tertiary Care Hospital in Nepal

Badri Kumar Gupta*, Binod Kumar Gupta, Amit Kumar Shrivastava, Pradeep Chetri

Abstract

Introduction: Sepsis is an important cause of morbidity and mortality among neonates. Neonatal sepsis can alter the glucose level and both hypoglycemia and hyperglycemia may occur. A high or low blood glucose level may have a significant effect on the outcome...

09/03/2019
Research Article

Does it matter what a mother consumes? An anthropological exploration of dietary practices among Churachandpur (Manipur) pregnant women and its impact on infant birth weight

Evelyn Ngaithianven, JS Sehrawat* and Reetinder Kaur

Abstract

Background: Nutritional status of expectant women is an important indicator of healthy pregnancy and an ideal birth weight of the infant. The present study is an attempt to understand food eating practices and related taboos among the Paite women and whether ...

10/04/2019
Research Article

Plaque morphology in diabetic vs. non diabetic patients assessed by Multi-Slice Computed Tomography coronary angiography

Hesham Mohamed Aboul-Enein, Amr Elsayed El Naggar, Shereen Ibrahim Farag, Waleed Atef Ahmed Hassan*

Abstract

Background and Objectives: Multi-slice computed tomography (MSCT) provides high accuracy for noninvasive assessment of coronary artery disease (CAD). The introduction of the latest computed tomography technology allows comprehensive evaluation of various aspe...

10/04/2019
Case Report

Scintigraphic non-invasive diagnosis of amyloid cardiomyopathy

Laroussi Mohamed-Salem*, Tomas E Rodríguez-Locarno, Tatiana Moreno-Monsalve, Isabel Castellon-Sanchez, Jose F Contreras-Gutierrez and Antonia Claver-Valderas

Introduction

Amyloidosis encompasses a heterogeneous group of disorders, characterized by extracellular deposition of insoluble abnormal amyloid aggregates, due to a failure in protein quality control. Cardiac amyloidosis is a disorder in which proteins misfold and deposit as amyloid ...

09/26/2019
Research Article

Prevalence of congenital heart diseases among primary school children in the Niger Delta Region of Nigeria, West Africa

Ujuanbi Amenawon Susan*, Tabansi Petronilla Nnena, Otaigbe Barbara Edewele

Abstract

Introduction: Congenital heart diseases (CHD) are leading causes of childhood morbidity and mortality especially in developing countries. Community-based studies are important in ascertaining the burden of the disease.

Objectives: T...

09/24/2019
Research Article

Novel paclitaxel-coated balloon angioplasty via single retrograde popliteal access for challenging superficial femoral artery and iliac artery lesions?

Erdem Cetin*, Celal Selcuk Unal, Aydın Keskin, Hakan Kartal

Summary

Objectives: We report our results regarding the use of BioPath™ paclitaxel-coated balloon catheters for superficial or distal external iliac artery revascularization via single retrograde popliteal access.

Methods: We included ...