July 2021

Pulmonary mucormycosis in post-pulmonary tuberculosis as an emerging risk factor: A rare case report

Divya Khanduja* and Naveen Pandhi

Abstract

Pulmonary mucormycosis is an uncommon pulmonary fungal disease, which is commonly seen in immunocompromised individuals. It is caused by fungi of class Zygomycetes. It constitutes the third most common invasive fungal infection following aspergillosis and candidiasis. Risk fa...

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A Case series on Asthma-COPD overlap (ACO) is independent from other chronic obstructive diseases (COPD and Asthma)

Divya Khanduja* and Naveen Pandhi

Abstract

As we know that, Asthma and chronic obstructive pulmonary diseases are well characterized diseases, they can co-exist as asthma-COPD overlap (ACO). The co-existence of asthma-chronic obstructive pulmonary disease overlap (ACO) in chronic obstructive pulmonary disease (COPD) p...

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A retrospective review of the factors that negatively influenced the eradication of polio in South-South, Nigeria

Peters Grace E*, Assi Victor, Oko Nnabuike E and Peters Etete J

Abstract

Background: The endemic nature of poliomyelitis in Nigeria was a source of concern to many given the global efforts aimed at eradicating the scourge. In this study, the factors that influenced the eradication of this malady in South-South Nigeria (Akwa Ibom and Cross River St...

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Cannabinoids as a yield modifier in physical activit: A systematic review characters

Leonardo Tibiriçá Corrêa, Juliana Weckx Peña Muñoz6, Beatriz do Prado Pacca Faria, Jeferson Santana, Leandro Yanase Rocha, EstherLopes Ricci, Lorena de Paula Pantaleon, Leonardo Ribeiro de Paula, Guilherme Mendes Ribeiro, Vinicius Barroso Hirota and André Rinaldi Fukushima*

Abstract

Marijuana is considered illicit in much of the world, and is classified as a drug for recreational use, in recent decades the medicinal use of Cannabis sativa L. has grown and diversified, being considered the only therapeutic alternative in the control of serious and incurab...

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Current challenges in plant breeding to achieve zero hunger and overcome biotic and abiotic stresses induced by the global climate changes: A review

Gniech Karasawa Marines Marli*

Abstract

According Sustainable Development goals until 2030 we should have zero hunger and undernourished people in the world. But to achieve this goal plant breeders must improve plants in order to produce at least the double than is produced now. This is not a easy pathway because w...

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The continued relevance of Deep Brain Stimulation for chronic pain

Sarah Marie Farrell and Tipu Aziz*

Abstract

For the millions of patients experiencing chronic pain despite pharmacotherapy, deep brain stimulation (DBS) provides a beacon of hope. Over the past decade the field has shifted away from DBS towards other forms of neuromodulation, particularly spinal cord stimulation (SCS)....

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Five-year follow up on the single level corpectomy

Frank Phillip Castro*

Single-level Anterior Cervical Decompression and Fusion (ACDF) was initially performed using Iliac Crest Bone Graft (ICBG) [1].

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The SARS CoV-2 spike domain, RGD and integrin binding effect-relationship for vaccine design strategy

Luisetto M*, Tarro G, Khaled Edbey, Almukthar N, Cabianca L, Mashori GR, Ahnaf Ilman, Yesvi AR and Latyschev OY

Abstract

Related the need to search new strategy in vaccine design in order to reduce also some rare effect like trombosys for some registered products it is interesting the role played by the SPIKE RGD domain.

The binding with molecules like Fibronectin is a process that mu...

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Sleep quality and associated factors among patients with chronic illness at South Wollo Zone Public Hospitals, Northeast Ethiopia

Afework Edmealem*, Sewunet Ademe and Atsedemariam Andualem

Abstract

Background: Pathological and nighttime sleep deprivations have substantial adverse effects on regulation of weight, sugar and blood pressure because of endothelial dysfunction, sympathetic nervous system stimulation, regulation and activation of systemic inflammation. Thus, thi...

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Malignancy induced haemophagocytosis by erthroid cells and its transformation into a multinucleated giant cells – A unique clinical image

Prachi*, Gaurav Sharma and Suparno Chakrabarti

Haemophagocytosis is a dysregulated immune condition characterised by both inflammation and uncontrolled activation of macrophages and T-cells, which causes aberrant cytokine release, leading to cytokine storm [1] it can be primary or secondary, depending upon the etiology.

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Atypical cutaneous relapse of multiple myeloma

Jean-Baptiste Rieu*, Francois Vergez, Jill Corre, Aurore Perrot and Pierre-Luc Mouchel

A 66-year-old patient, diagnosed κ light chains MM with t(11;14), presented before second cycle with bendamustine-dexamethasone.

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Myxedema coma in COVID-19

Yuichi Takashi* and Daiji Kawanami*

Abstract

SARS-CoV-2 infection is associated with thyroid disorders. It has been reported that myxedema coma (MC) can be complicated with COVID-19. COVID-19-related thyroid disorders consist of a broad spectrum of thyroid dysfunction, from thyrotoxicosis to decompensated hypothyroidism...

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Blunt abdominal trauma with duodenal dissection: A case report

Basile Essola*, Jean Baptiste Boumsong Batamag, Jean Paul Engbang, Dominique Djomo, Esdras Ngaroua, Jacques Landenne and Jean Gustave Tsiagadigui

Abstract

We describe a new case of duodenal wound with complete transection in a 22-year-old patient following a motorcycle accident. He presented to the emergency room of the rural Regional Hospital of Edéa in Cameroon with a clinical picture of acute abdomen and post-trauma h...

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Practice patterns and outcomes of repository corticotropin injection (Acthar® Gel) use in childhood nephrotic syndrome: A study of the North American Pediatric Renal Trials and collaborative studies and the Pediatric Nephrology Research Consortium

Mohammed K Faizan*, Courtney McCracken, Kenneth Lieberman, Traci Leong and Mark R Benfield

Summary

Objective: We set up a U.S. registry to examine prescription patterns and patient outcomes of repository corticotropin injection (Acthar® Gel) for childhood nephrotic syndrome.

Methods: 18 participating U.S. pediatric centers performed retrospective review and pr...

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Multifrecuency bioimpedance phase angle as a tool to predict maturation failure of native fistulae for hemodialysis

José Lucas Daza Lopez*, John F Galindo, Mónica R Villaquiran, Emilio D Valenzuela, Andres Cardenas, Luis Jose Daza6, Maria Camila Correcha, Jonathan de Jong, Yaroslad De La Cruz Prieto, Gerardo Gutierrez and Luis Puello

Summary

Background and objectives: An arteriovenous fistula is considered to be an ideal vascular access for patients receiving hemodialysis, its main limitation is its high failure rate to achieve maturation and long-term functionality loss. Multiple strategies have attempted to iden...

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Usefulness of foot-to-foot bioimpedance analysis for assessing volume status in chronic hemodialysis patients at the Aristide Le Dantec University Hospital (Senegal)

Niakhaleen Keita*, Maria Faye, Sidy Mouhamed Seck, Boucar Ndong, Moustapha Faye, Ahmed Tall Lemrabott, Bacary Ba, Seynabou Diagne1, Mansour Mbengue, Ameth Dieng, Mamadou Aw Ba, Abdou Sy, Modou Ndongo, Babacar Ndiaye and Elhadji Fary Ka

Summary

Introduction: Determination of dry weight is one of the daily goals to achieve in hemodialysis. The aim of this study was to validate the use of bioelectrical impedance analysis (BIA) in estimation of dry weight in a population of Senegalese chronic hemodialysis patients.

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Management outcome of intestinal obstruction done by integrated emergency surgical officers and its associated factors in selected district hospitals of South Wollo Zone, North East Ethiopia in 2019 G.C

Sewunet Ademe*, Afework Edmealem, Belachew Tegegne and Zemen Mengesha

Abstract

Background: Intestinal obstruction (IO) is defined as a partial or complete blockage of the bowel that results in the failure of intestinal contents to pass through. It is a common cause of emergency surgical problems. IO has been the leading cause of acute abdomen in several...

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Gallstone Ileus with associated perforated small bowel diverticulitis

Shreeja Mehrotra*, Yang Huang, Ronan Knittel and Palan Thirunavukkarasu

Gallstone ileus is a rare complication of cholelithiasis and a type of mechanical obstruction involving impaction of a gallstone within the intestinal tract [1,2]. This entity occurs in 0.15% - 1.5% of cholelithiasis cases and < 0.1% of ileus cases overall [1]. Gallstone ileus is more common i...

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COVID-19 Associated acute limb ischemia

Yogendra Mishra*, Satish Kumar and Meghna K

A 78-year-old man, known case of, diabetes mellitus, and hypertension presented with fever, dry cough and dyspnea of five-day duration.

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Comparative efficacy of inspiratory, expiratory and combined respiratory muscle training on the pulmonary functions and chest expansion in acute stroke survivors

Adeogun Abiodun A* and Umar Dolapo K

Abstract

Background: Respiratory muscle strength can be reduced in patients diagnosed with stroke, which reasonably justifies the use of respiratory muscle training in this population. This study determines the comparative efficacy of inspiratory, expiratory, and combined respiratory ...

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Acute Kidney Injury due to spontaneous Atheroembolic disease, superimposed on diabetic nephropathy, with no recent vascular or cardiac intervention, presented as Rapidly Progressive Glomerulonephritis (RPGN)

Anas Diab*, Parravani Anthony, Hollie Berryman and Kareem Diab

Atheroembolic disease (AED), or Cholesterol Crystals Embolism, is a systemic disease presented as a complication of severe atherosclerosis [1], where older age, male sex, diabetes hypercholesterolemia, smoking and hypertension [2], are the main risk factors for the development of  Atheroscle...

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Hypertension: A global health crisis

Pius AL Berek*, Dewi Irawati and Akhir Yani S Hamid

Abstract

Objective: This study discusses strategies to overcome hypertension patient compliance to manage self-care. The purpose of the study is to provide a summary of the importance of attention to managing hypertension.

Method: a review of literature relevant to hypertens...

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Multimodal treatment strategies in Huntington’s disease

Rajib Dutta*

Abstract

Huntington’s disease (HD) is an incurable neurodegenerative disease that causes involuntary movements, emotional lability, and cognitive dysfunction. HD symptoms usually develop between ages 30 and 50, but can appear as early as 2 or as late as 80 years. Currently no ne...

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Revisiting childhood pneumonia in low-recourse setting hospitals

Karimeldin MA Salih*

Abstract

Introduction: Pneumonia, defined as infection of lung parenchyma, is associated with severe complications especially in the very young and old patients. It is the world’s leading cause of childhood mortality. The World Health Organization (WHO) classification and guidel...

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AsdamarinTM relieves functional dyspepsia in healthy adults in only 7 days: A randomized, double-blind, placebo-controlled pilot study

David Daguet*, Sudeep Heggar Venkataramana, Justin V Thomas and Shyam Prasad Kodimule

Abstract

Functional dyspepsia (FD) is a prevalent global health concern increasing with years. Inspired by the Traditional Chinese Medicine (TCM) liver-stomach disharmony syndrome in order to find a quick natural alternative treatment, a Ferula asafoetida-Silybum marianum (Asdamarin&t...

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Facial-onset sensory-motor neuronopathy, a rare variant of Huntington’s disease or chance association?

Raul Juntas-Morales, Elisa De La Cruz, Florence Esselin, Nicolas Pageot, Guillaume Taieb and William Camu*

Abstract

Objectives: To describe a patient with facial-onset sensory-motor neuronopathy (FOSMN) that later developed Huntington’s disease (HD).

Case report: A 62-year-old woman complained of progressive dysphagia 8 years before referral. At initial evaluation, there wa...

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Epidemiological profile of the homeless population assisted by voluntary initiative and the social impact on access to healthcare: an investigative study in Curitiba, Brazil

Rafael Senff Gomes, Luiza Cardoso de Lima Passoni, Ricardo Sirigatti and Francelise Bridi Cavassin*

Summary

Objective: The study aimed to describe the epidemiological profile of the homeless population and report the social impact on healthcare services provided by a voluntary initiative during one-year of follow-up.

Method: This is an investigational study, carried out in...

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Open heart surgery in Nigerian children the need for international and regional collaboration: The Bayelsa and Enugu experience

Ujunwa FA, Ujuanbi AS, Chinawa JM*, Allagoa DO and Onwubere B

Abstract

Background: Children with congenital heart diseases (CHD) often require palliative or definitive surgical heart interventions to restore cardiopulmonary function. Lack of early cardiac intervention contributes to large numbers of potentially preventable deaths and sufferings ...

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Nurses knowledge and practice in assessment and management of neonatal pain at Governmental Hospitals in Gaza Strip: A cross sectional study

Yunis KS Qasim*, Hamza Abdeljawad and Ali H Abusafia

Abstract

Objective: The study aimed to investigate neonatal nurses' knowledge and practices related to pain assessment and management that may contribute to improve the quality of pain management by nurses at Neonatal Intensive Care Units (NICUs) of governmental hospitals in Gaza ...

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Novel Coronavirus Disease (COVID-19): An extensive study on evolution, global health, drug targets and vaccines

Abdul Ashik Khan, Tanmoy Dutta, Palas Mondal, Manab Mandal, Swapan Kumar Chowdhury, Minhajuddin Ahmed, Nabajyoti Baildya, Sourav Mazumdar and Narendra Nath Ghosh*

Abstract

The Coronavirus disease-2019 (COVID-19), has become a worldwide pandemic and the scientific communities are struggling to find out the ultimate treatment strategies against this lethal virus, Severe Acute Respiratory Syndrome Coronavirus–2 (SARS-CoV-2). Presently, there...

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OPEN and CLOSED state of SPIKE SARS-COV-2: relationship with some integrin binding. A biological molecular approach to better understand the coagulant effect

Luisetto M, Khaled Edbey, Mashori GR, Ahnaf Ilman, Yesvi AR and Latyschev OY

Abstract

Related the physio-pathological process of COVID-19 disease it is interesting to focus to the aspect.

Played by interaction of Sars-Cov-2 protein with integrins of human epithelial pulmonary cell.

A bio molecular approach help in to deeply verify the invol...

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Role of neuron specific enolase as a biomarker in Parkinson’s disease

Rajib Dutta*

Abstract

Parkinson’s disease (PD) is thought to be the most common neurodegenerative disease with movement disorder. The key motor symptoms are rigidity, tremor, akinesis/hypokinesia/bradykinesia, and postural instability. However, in our day-to-day clinical practice we tend to ...

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