01/30/2021
Research Article

Maximal stability limits in adolescents with Tourette syndrome

Mariève Blanchet*, François Prince, Martin Lemay, Sylvain Chouinard and Julie Messier

Abstract

We explored if adolescents with Gilles de la Tourette syndrome (GTS) had functional postural control impairments and how these deficits are linked to a disturbance in the processing and integration of sensory information. We evaluated the displacements of the center of pressu...

01/29/2021
Review Article

Illness of great dictators - mosaic psychopatia

Dmitrieva Elena Germanovna*

Abstract

Psychopatia is a borderline between mental diseases and good health. One of its versions is mosaic psychopatia. For certain everyone knows, that the mosaic represents. These are the parts of diverse elements collected together. And so this disease is named after the patient s...

01/29/2021
Short Communication

Differences between anorexia patients and participants of the Minnesota hunger experiment: Consequences for treatment

Greta Noordenbos*

The hunger experiment was carried out in 1944 by Anselm Keys and others in the American city of Minnesota. The aim was to investigate the consequences of starvation in order to be able to restore the health of hunger victims of the Second World War. How could they be treated in the best possible ...

01/28/2021
Research Article

Induction therapy with Erlotinib (E) and Gemcitabine/Platinum (GP) in stage III NSCLC

Tobias R Overbeck*, Stefan HP Wenleder*, Bernhard C Danner, Wolfgang Körber, Karin Toepelt, Bernhard Hemmerlein, Christina Perske, Markus Falk, Markus Tiemann, Claudia Tomala, Elke Stitz and Frank Griesinger

Abstract

Background: In 2004 we started a phase II trial in non-small lung cancer (NSCLC), stage III, with erlotinib followed by a combination with a platinum-based doublet in unselected patients to identify molecular subgroups benefitting from an EGFR targeting approach.

Pa...

01/27/2021
Review Article

Exploring COVID-19: Relating the spike protein to infectivity, pathogenicity and Immunogenicity

Vinod Nikhra*

Abstract

Introduction: SARS-CoV-2 life cycle: The disease which reportedly began in Chinese city Wuhan in November-December 2019 manifesting as severe respiratory illness, soon spread to various parts of the world, and was named COVID-19, and declared a pandemic by WHO. The life cycle...

01/26/2021
Mini Review

Physical activity can change the physiological and psychological circumstances during COVID-19 pandemic: A narrative review

Khashayar Maroufi*

Abstract

Background: With the outbreak of Coronavirus disease 2019 (COVID-19), many studies’ attention to this world’s complexity increased dramatically. Different views on sports and physical activities have been presented, which have addressed the advantages and disadvan...

01/29/2021
Research Article

Suicidal behaviors as a risk factor among heroin addicts with comorbid depression: A comparative study

Nazia Mustafa* and Fahad Haleem

Abstract

The main purpose of the present study was to find out the differences on suicidal ideation, hostility, hopelessness and negative self-evaluation among heroin addicts with comorbid depression. After reviewing the literature, it was hypothesized that heroin addicts with high de...

01/25/2021
Thesis

After human: The world of brain-net on earth

Sadique Shaikh*

“The mind of man is capable of anything….because everything in in it, all the past as well as all the future [Joseph Conrad]”. Why I am using above quote and what is the relation to what point I am coining you will understand its relevant your own as you moving line by line of ...

01/21/2021
Mini Review

Climate and garbage

Khalidullin Oleg*

Review

Humanity has destroyed 70% of the land by arable land, reservoirs, asphalt, concrete, garbage and ore landfills.

01/20/2021
Clinical Image

Hyperacute fatal course in a hypercalcemic crisis

Sara Turco*, Alice Chiara Manetti, Aniello Maiese, Matteo Scopetti and Marco Di Paolo

Clinical Image

A 39-year-old woman, with a not significant past medical history, entered the Emergency Department complaining about nausea, vomiting, constipation, anorexia, deep asthenia, and diffuse muscle aches with cramps. She referred sporadic diarrhea (one episode) the day befor...

01/20/2021
Research Article

Chemical constituents and biological activities of Artocarpus heterophyllus lam (Jackfruit): A review

Pranay Raja Bhad, Meeneri Vilas Bobde and Sibi G*

Abstract

Artocarpus (Moraceae) is a deciduous tree with appreciable importance as a source of edible fruit and is widely used in folk medicines. The extracts and metabolites of Artocarpus heterophyllus particularly those from leaves, bark, stem and fruit possess several useful bioacti...

01/19/2021
Research Article

Association between obesity profile and non-alcoholic fatty liver by race/ethnicity

Martin Galindo, Katrina M Schrode and Magda Shaheen*

Abstract

NAFLD is characterized by accumulation of fat in the liver that can lead to health complications. Previous studies have found the obesity phenotype and its components to be risk factors for the development of NAFLD. This study aims to examine the relationship between the obes...

01/20/2021
Research Article

Epidemiologic aspects and risk factors associated with infertility in women undergoing assisted reproductive technology (ART) in north of Iran

Marzieh Zamaniyan, Noushin Gordani٭, Paniz Bagheri, Kaveh Jafari, Sepideh Peyvandi, Mojtaba Hajihoseini, Robabeh Taheripanah, Siavash Moradi, Salomeh Peyvandi and Arman Alborzi

Abstract

Objective: This study aimed to investigating of the epidemiological aspects of infertility and related risk factors in infertile women.

Materials and methods: This cross-sectional study, carried out on 330 infertile women referred to two infertility treatment center...

01/18/2021
Case Report

A rare case of giant ovarian serous cystadenoma presenting as psuedo-meigs syndrome

Richmond Ronald Gomes*, Sayeda Noureen and Habiba Akhter

Abstract

Meigs’ syndrome is a rare condition characterized by the presence of a benign fibroma of the ovary, ascites and pleural effusion. Other benign cysts of the ovary (such as struma ovarii, mucinous cystadenoma, serous cystadenoma and teratomas), leiomyoma of the uterus, an...

01/20/2021
Research Article

The clinicopathological correlates of Cystoisosporiasis in immunocompetent, immunocompromised and HIV-infected/AIDS patients, but neglected in SARS-COV-2/COVID-19 patients?

Chrysanthus Chukwuma Sr*

Abstract

Cystoisosporiasis (formerly isosporiasis) is caused by Cystoisospora belli (erstwhile named Isospora belli) is encountered globally, particularly in tropical and subtropical regions. Cystoisosporiasis is a human intestinal disease whose etiology is the parasite Cystoisospora ...

01/20/2021
Review Article

The coral crunch: Amyloidoma

Anubha Bajaj*

Preface

Amyloidoma is an exceptional, progressive disorder demonstrating a characteristic accumulation of significant quantities of amyloid within soft tissues. Amyloidoma is additionally nomenclated as tumoural amyloidosis, nodular amyloid or localized amyloidosis. Furthermore, insul...

01/19/2021
Review Article

The review of the relationship between UCP2 and obesity: Focusing on inflammatory-obesity

Sara Moradi, Yaser Khaje-Bishak, Maedeh Alipour, Mohamadreza Alivand* and Beitullah Alipour*

Abstract

Obesity is rising worldwide, and the inflammatory disease increased in parallel. Many studies demonstrate excess fat mass is an indicator of obesity. As much as lipid increased in the cell, ROS production increased. On the other hand, ROS could enhance lipid storage and incre...

01/15/2021
Review Article

New insights from cardiac muscle applied to skeletal muscle

Gerry A Smith*

I have recently described the origin of the second Ca2+ binding in the triggering of contractile activity in cardiac myofibrils that is the origin of the Ca2+ Hill coefficient of 2 for the ATPase. This site is not a simple protein binding site and cannot be measured by 45Ca2+ binding. The myofibr...

01/15/2021
Research Article

Pig raising practices by unprivileged, ethnic people in Bangladesh

Ausraful Islam*, Ashika Akbar Trisha, Md. Safiul Ahad Sardar, Mohammady Akbor, Abdulla Al Mamun Bhuyan, Md. Sazzad Hossain, Md. Ashraf Zaman Faruk, Sheikh Muhammad Khaled Sharif, Zannatun Nahar and Anisuzzaman

Abstract

We interviewed 207 pig raisers from seven different districts of Bangladesh to explore their practices related to their pig farming. We used structured questionnaires to interview the pig raisers and used descriptive statistics for analysis. Most of the pig raisers (54%) were...

01/13/2021
Case Report

Soliter fibrous tumor of diaphragm in a patient with larynx cancer: Case report

Bengisu Arabaci*, Kenan Can Ceylan, Sulun Ermete, Devrim Kilic and Seyda Ors Kaya

Summary

Introduction: Solitary fibrous tumor is a neoplasm of mesenchymal origin with benign and malignant forms. We aimed to present a case of solitary fibrous tumor which developed in a patient operated for laryngeal cancer and originated from diaphragm in the light of the literatur...

01/13/2021
Research Article

C3D data based on 2-dimensional images from video camera

Ali Sharifnezhad*, Mina Abdollahzadekan, Mehdi Shafieian and Iman Sahafnejad-Mohammadi

Abstract

The Human three-dimensional (3D) musculoskeletal model is based on motion analysis methods and can be obtained by particular motion capture systems that export 3D data with coordinate 3D (C3D) format. Unique cameras and specific software are essential for analyzing the data. ...

01/12/2021
Research Article

Glomerular hyperfiltration in Yemeni children with sickle cell disease

Abdul-Wahab M Al-Saqladi* and Fatima E Al-Musawa

Abstract

Background: Glomerular hyperfiltration (GH) is a common feature of sickle cell nephropathy (SCN) starting at infancy and represents an early marker of incipient glomerular injury and renal dysfunction.

Methods: This study aimed to determine the prevalence and correl...

01/12/2021
Short Communication

Hypertensive toxicity of thyrosine kinase inhibitors; Friend or Foe?

Ergün Barış Kaya and Yusuf Ziya Şener*

Abstract

Tyrosine kinase inhibitors (TKIs) are widely used in Oncology practice. Hypertension may develop during cancer treatment and TKIs are well known drugs that are associated with drug related hypertensive toxicity. TKI related hypertensive toxicity is not always the indicator of...

01/12/2021
Case Report

PET/MRI, aiming to improve the target for Fractionated Stereotactic Radiotherapy (FSRT) in recurrence of resected skull base meningioma after 2 years: Case report

Sebastião Corrêa*

Abstract

The increasing use of highly conformal radiation deliberates a higher accurate targeting. Contouring and clinical judgment are presumably the crucial point, thus positron emission tomography/magnetic resonance imaging PET/MRI with somatostatin analogs appears to be useful in ...

01/11/2021
Mini Review

Stem cell therapy in children with acute liver failure: The dream could come true

Riham Rabie Issa*, Ahmad Mohamed Sira and Mostafa Mohamed Sira

Abstract

Acute liver failure (ALF) in children is a severe disease with a high mortality rate. The current treatment strategies are still defective, with many cases die when liver transplantation is unavailable. The current protocol of steroids therapy improved the survival rate of he...

01/11/2021
Case Report

Acute urinary retention and hyponatremia from central hypothyroidism

Samson Erkabu*, Zerihun Taddese, Biniam Bearega, Eyuel Daniel and Mekonen Birhanu

Abstract

A mass arising from the pituitary gland commonly damages cells of the anterior pituitary gland and affects the secretion of gonadotropins and growth hormone. However, central hypothyroidism and secondary adrenal insufficiency from such damage is a rare phenomenon. Acute urina...

01/15/2021
Research Article

Evaluation of influence of IL-6 C-572G gene polymorphism and clinical factors on positive platelet antibody test

Jeong-Shi Lin*, Li-Hsuan Lee, Hsueng-Mei Liu, Ying-Ju Chen and Tzeon-Jye Chiou*

Abstract

Background: Interleukin-6 (IL-6) promotes antibody production. The objective of this study was to investigate whether IL-6 C-572G single nucleotide polymorphisms (SNP) and clinical factors are associated with positive platelet antibody test.

Materials and methods: T...

01/11/2021
Case Report

Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): A case with adverse reaction to three drugs alternately administered

Sergio Manieri*, Maria P Mirauda, Fabiola De Gregorio, Carmela Colangelo, Maria Tagliente, Rosaria Abate, Luciana Romaniello, Rosa Lapolla and Donatello Salvatore

Abstract

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a severe multiorgan hypersensitivity reaction mostly caused by several eliciting drugs in patients with a genetic predisposition. Incidence of DRESS in children is very variable, frome 1:1000 to 1:10.00...

01/08/2021
Opinion

The use of the scientific method as dogma can be an obstacle in times of pandemic

Felipe Inserra, Walter Manucha* and León Ferder

Science is not inherently dogmatic. On the contrary, in our opinion and according to Bachelard, it often breaks with certain dogmas [1]. That is why it must have the necessary flexibility to be able to analyze and incorporate exceptional situations. In this regard, the current Coronavirus pandemi...

01/15/2021
Mini Review

Three visionaries for HRT

Joseph Loze Onwude*

When a woman consults a doctor about Hormone Replacement Therapy (HRT), the first concern is that there is an increased risk of breast cancer with HRT. And this sole reason might be the reason for refusing the offer of HRT. However, this practice has minimal basis and evidence to support it.

01/12/2021
Research Article

An audit on outpatient hysteroscopy – cervical dilatation, failure rates and patient satisfaction

Sophie Boyd* and S Lalchandani

Abstract

Aims: To audit the use of cervical dilators, local anaesthetic, and failure rates in outpatient hysteroscopy over a two-year period in University Hospital Kerry. To review the experiences of women attending the outpatient hysteroscopy clinic (OHC) over a two-year period in Un...

01/04/2021
Research Article

The effect of NLP-based approach to teaching surgical procedures to senior OBGYN residents

Mitra Ahmad Soltani, Jamileh Jahanbakhsh*, Zahra Takhty, Azarmindokht Shojai and Hengameh Sheikh

Each individual has a unique way of learning which is based on personal background [1]. Neuro Linguistic Programming is an ideology of communicating with an individual. It can be applied in social relations like teaching fields [2]. Each medical student deals with a set of new information in his ...

01/05/2021
Research Article

Evidence of woven bone formation in carotid artery plaques

Mirzaie Masoud*, Zaur Guliyev, Michael Schultz, Peter Schwartz, Johann Philipp Addicks and Sheila Fatehpur

Abstract

Objective: Plaque morphology plays an important prognostic role in the occurrence of cerebrovascular events. Echolucent and heterogeneous plaques, in particular, carry an increased risk of subsequent stroke. Depending on the quality of the plaque echogenicity based on B-mode ...

01/01/2021
Short Communication

Fears of health catastrophe as Nepal reports increasing deaths from COVID-19

Hom Nath Chalise*

Abstract

Coronavirus disease 2019 (COVID-19) had affected both developed and developing countries too. The first case in Nepal was confirmed on 23 January 2020.  It was also the first recorded case of COVID-19 in South Asia. Nepal reported its first COVID-19 death on May 16. At t...