02/25/2021
Research Article

A comparative study of single or dual treatment of theranostic 188Re-Liposome on microRNA expressive profiles of orthotopic human head and neck tumor model

Shan-Ying Wang, Liang-Ting Lin, Bing-Ze Linchih, Chih-Hsien Chang, Chun-Yuan Chang, Min-Ying Lin and Yi-Jang Lee*

Abstract

Background: 188Re-liposome has been used for evaluating the theranostic efficacy on human head and neck squamous cell carcinoma (HNSCC) at preclinical stages. Here we furthercompared the microRNA expressive profile in orthtopic HNSCC tumor model exposed to 188Re-liposome.

...

02/23/2021
Case Report

Ipratropium induced bronchoconstriction in a young Asthmatic: A case report

H Aleshaa*, J Collindridge and RK Singh

Acute severe Asthma is a common paediatric emergency managed according to the BTS and SIGN guidelines. They recommend that if initial β2 agonist treatment bears no response, frequent Ipratropium Bromide doses can be given every 20-30 minutes [1]. We present a case of paradoxical bronchospasm...

02/19/2021
Research Article

Fluorinated nematicides: Novel classes in the way

Mohamed S Khalil* and Rasha E Selim

Abstract

The demand on non- fumigant nematicides was strongly increased in the last few years, and this interesting in nematicides are due to farmers are needed for safer pesticides and increasing of the regulatory pressure on many of the traditional nematicides. The control of plant ...

02/18/2021
Research Article

Psychotropic drugs prescription block the positive effects of the doctor-patient communication and relationship

Jose Luis Turabian*

Abstract

The fact that general practitioner (GP) or psychiatrist understands the psychosocial effects of prescribing on the doctor-patient relationship is as important, if not more so, than knowing pharmacology. Any prescription of drugs modifies the doctor-patient relationship. Drugs...

02/16/2021
Case Report

Papillary thyroid cancer and cervical lymph mode metastases – optimal preoperative evaluation

George H Sakorafas*

Papillary thyroid cancer (PTC) is the most common subtype of thyroid cancer and a highly curable malignancy [1]. However, despite its excellent prognosis, cervical lymph node metastases (CLNMs) are present in a significant percentage of patients with papillary thyroid cancer (PTC) (upto 50% &ndas...

02/17/2021
Research Article

A retrospective cohort study to evaluate the relationship of airway hyperresponsiveness to type 2 biomarkers in persistent asthma

Rory Chan, Chris RuiWen Kuo and Brian Lipworth*

Abstract

Airway hyperresponsiveness (AHR) is a hallmark of persistent asthma measured using direct or indirect airway bronchial challenge testing. The purpose of this study is to investigate the putative relationships between type 2 inflammatory biomarkers, airway geometry (FEV1 and F...

02/16/2021
Research Article

COVID-19 New variant and air pollution relationship: how airborne mutagens agent can act on genoma viruses expression: Hypothesis of work

Luisetto M, Naseer Almukthar, Gamal Abdul Hamid, Tarro G, Khaled Edbey, Nili BA, Ghulam Rasool Mashori, Ahmed Yesvi Rafa and Latyshev O Yu

Abstract

Before actual COVID-19 pandemia coronavirus was not so dangerous like now.
In December 2019 - January 2020 in Wuhan first and then in other places this coronavirus was responsible of a first wave of severe pulmonitis responsible of many deaths.

Wuhan and othe...

02/16/2021
Review Article

Living with ‘Long COVID-19’: The long-term complications and sequelae

Vinod Nikhra*

Abstract

Introduction - the perennial pandemic: It is being increasingly realised that the COVID-19 may have become the new reality associated with human existence world over and the mankind may have to live with it for years or even decades. Further, the grievous nature of the diseas...

02/15/2021
Research Article

FITT-CORRECT: Updated dynamic and evidence-based principle of exercise prescription

Shambhu P Adhikari*, Jarugool Tretriluxana, Rubee Dev, Emily Eglitis, Nistha Shrestha and Cheryl Kerfeld

Abstract

Objective: The FITT (Frequency, Intensity, Time, and Type) principle is an effective foundation in EP. However, the CORRECT components; C–Combination of interventions, O–Order of the Interventions, R–Repetitions, R–Rest period between sets and between ...

02/15/2021
Case Report

Recurrent hydrothorax due to diaphragmatic perforation post hepatocellular carcinoma radiofrequency ablation: A case report

Laia Aceituno*, Alba Prió, Fernando L Ascanio, Xavier Serres-Créixams, Beatríz Mínguez, Joan Genescà, Lluís Castells and Ares A Villagrasa

Abstract

Radiofrequency ablation is one of the most commonly used therapies for potentially curative small hepatocellular carcinoma. Although radiofrequency is usually a safe procedure, severe and potentially fatal complications can happen. This is a case of a 72 years old woman with ...

02/18/2021
Review Article

Drug treatment and rehabilitation in China: Theoretical rationales and current situations

Gloria Yuxuan Gu* and Hua Zhong

Global drug use has reached epidemic levels, with approximately 269 million drug users worldwide [1]. Problematic drug use may lead to serious physical, social, and mental health problems.

02/15/2021
Research Article

Estimation of cotinine level among the tobacco users and nonusers: A cross-sectional study among the Indian population

Sukhvinder Singh Oberoi* and Avneet Oberoi

Abstract

Background: Epidemiological studies in smokers indicate a dose-response relationship between the number of cigarettes smoked per day and the risk of developing certain smoking related diseases. The alkaloid nicotine is the major pharmacologically active substance in tobacco.<...

02/15/2021
Research Article

Comparison of clinical, chest CT and laboratory findings of suspected COVID-19 inpatients with positive and negative RT-PCR

Gokhan Perincek, Canver Onal and Sema Avci*

Abstract

Introduction: COVID-19 is an infectious disease caused by the severe acute respiratory syndrome coronavirus 2 and it was first reported in China. The aim of this study was to compare clinical features, chest CT findings and laboratory examinations of suspected COVID-19 inpati...

02/12/2021
Clinical Image

Severe hypertriglycerdemia in pregnancy

Krithika Muralidhara* and Shashank Dhareshwar

31 year old female presented with abdominal pain and respiratory distress in the third trimester of her second pregnancy.

02/05/2021
Research Article

Helping asthmatic children through bonding therapy

Antonio Madrid* and Nicholas Bennett

Abstract

Disruptions in Maternal-infant Bonding are shown to be the mediating variable between maternal distress and the subsequent expression of childhood asthma. When the mothers’ bonding is repaired, their children’s asthmatic symptoms diminish or remit. This study eval...

02/12/2021
Case Report

An unusual presentation of atrioventricular nodal reentrant tachycardia

Florina-Adriana Ghitun, Stefan Ailoaei, Dan Ursu, Raluca Chistol, Grigore Tinica, Cristian Statescu and Mihaela Grecu

Summary

Introduction: Atrioventricular nodal reentrant tachycardia (AVNRT) is the most frequent supraventricular tachycardia, commonly manifesting as autolimited paroxysmal episodes of rapid regular palpitations that exceed 150 beats per minute (bpm), dizziness and pounding neck sensa...

02/11/2021
Research Article

The impact of the surgical mask on the relationship between patient and family nurse in primary care

Ana Raquel Braga* and Irene P Carvalho

Abstract

Objective: In primary care, during treatments, nurses may need to wear surgical masks, namely for control of infection contamination, or to minimize unpleasant odors. The goal of this study is to inspect the effect of nurses wearing the mask on patient perception of the nurse...

02/10/2021
Case Report

Limb ischemia after coil migration used for a hypogastric aneurysm embolization

Miquel Gil Olaria*, Natalia Hernandez Wiesendanger, Clàudia Riera Hernández, Carlos Esteban Gracia and Secundino Llagostera Pujol

Summary

Hypogastric artery aneurysms are an uncommon entity. When the diameter achieves > 30-35 mm, they should be treated. Endovascular repair may be considered as first line therapy. One therapeutic option for internal iliac artery aneurysm exclusion is its embolization with or w...

02/11/2021
Research Article

Circulating salusin-beta levels in the patients with age-related macular degeneration

Burak Turgut*, Kadir Mercan, Nesrin Demir, Nevin Ilhan and Onur Çatak

Abstract

Purpose: To evaluate the levels of salusin-beta (β-SAL) in the serum in patients with age-related macular degeneration (ARMD).

Methods: Our study was designed as a controlled comparative clinical study. The β-SAL levels in serums of age and sex-matched 20 ...

02/10/2021
Research Article

A study of coagulation profile in patients with cancer in a tertiary care hospital

Gaurav Khichariya, Manjula K*, Subhashish Das and Kalyani R

The complicated process of cancer triggers many physiological systems like vascular endothelial functions and hemostasis, which signifies the increased risk of thrombosis, which triggers thromboembolic events resulting in increased mortality and morbidity [1-3]. Tumorigenesis contributes by activ...

02/10/2021
Research Article

Prospective study of pain and psychological symptoms of first-year university students

Airi Oksanen*, Katri Laimi, Eliisa Löyttyniemi and Kristina Kunttu

Abstract

Background: Even if pain and psychological symptoms experienced by university students are common, the prognosis of these symptoms is unknown.
Objective: To examine the incidence and the outcome of frequent musculoskeletal and psychological symptoms in a 4-year follow-...

02/09/2021
Case Report

Cholecysto-colonic fistula after xanthogranulomatous cholecystitis: Surgeon’s nightmare

Karan Agarwal and Badareesh Lakshminarayana*

Xanthogranulomatous cholecystitis is a rare benign inflammatory disease of gallbladder that may be misdiagnosed as carcinoma of the gallbladder intraoperative or in pre-operative imaging. Intramural accumulation of lipid-laden macrophages and acute and chronic inflammatory cells is the hallmark o...

02/04/2021
Review Article

Polyolefin nanocomposites based on metallocene catalysts

Walter Kaminsky*

In recent years polyolefin nanocomposites are of great interest because of their high potential as materials with novel properties [1,2].

02/03/2021
Research Article

Iodine status and thyroid parameters of pregnant women living in an iodine sufficient area

Hossein Delshad, Parvin Mirmiran, Ladan Mehran, Maryam Tohidi and Fereidoun Azizi*

Abstract

During the last few decades painstaking efforts have been made to eliminate iodine deficiency throughout the world. Todays in regions where dietary iodine intake is adequate or borderline, the main focus is increasing dietary iodine supply in the target population during preg...

02/05/2021
Research Article

Characterization and virulence determination of Colletotrichum kahawae isolates from Gidami, Western Ethiopia

Zenebe W*, Daniel T and Weyessa G

Abstract

Coffee is one of the most essential crops that generate income for Ethiopian economic growth. However, its production faced with many factors primarily biotic entities. Among these, the fungal pathogen/Colletotrichum kahawae/that induce coffee berry disease (CBD) is the main ...

02/02/2021
Research Article

Alternative method for the transformation of Capsicum species

Mate Toth, Zoltan Szabo and Zoltan Toth*

Abstract

Capsicum (pepper) species have high economic values as vegetable crops and medicinal plants. Most of the Capsicum is known to be recalcitrant to plant regeneration in vitro, and to genetic transformation with Agrobacterium tumefaciens. However, genetic improvement against pat...

02/01/2021
Case Report

COVID-19: A unique opportunity for population health to align with nursing schools to help vulnerable populations at risk of adverse outcomes

Eileen Haley, MSN, RN., Victoria Harris, MPH., Parag Agnihotri, MD., Jamie Kwak and Ming Tai-Seale, PhD, MPH*

COVID-9 created a public health crisis shutting down many normal day-to-day activities and adversely affecting life, as we know it.

02/01/2021
Review Article

Systematic review and meta-analysis of drug induced liver injury secondary to biologic medications in inflammatory bowel disease

Eyad Gadour* and Zeinab Hassan

Abstract

Introduction: Drug-induced Hepatotoxicity and biologic drugs have historically been challenging in IBD. We aim to study the prevalence of hepatotoxicity in adult patients using biologic medications.

Methodology: With the guidelines described by PRISMA-P, a detailed ...

02/01/2021
Case Report

Anal cancer - impact of interstitial brachytherapy

Kubecová M, Vránová J, Šejdová M and Regináčová K*

Summary

We evaluated a total of 115 patients diagnosed with anal cancer, who were treated at our clinic from 1995 to 2012. Their average age was 61 years, most often were diagnosed in stages II and III, in most cases it was a squamous cell carcinoma located in the anal canal. The mean...