01/20/2020
Case Report

Granulomatosis with polyangiitis (GPA) in a 76-year old woman presenting with pulmonary nodule and accelerating acute kidney injury

Noor Sameh Darwich, Melissa Schnell and L. Nicholas Cossey

Abstract

Granulomatosis with polyangiitis (GPA), a form of ANCA-associated vasculitis (AAV), is a rare disease with an often-occult presentation. It is more common in 4th and 5th decades of life but can be seen in all ages.

This case report details a 76-year-old female prese...

01/14/2020
Research Article

Uterine precursor lesions in patients with incidental nodal lymphangioleiomyomatosis: A report of 4 cases

Charles M Lombard*

Abstract

Uterine sections from 6 patients with incidental nodal lymphangioleiomyomatosis (LAM) were examined for LAM lesions by screening these sections with cathepsin K immunohistochemistry (IHC) stains. The hysterectomy specimens were all concurrent with the lymph node dissections i...

01/13/2020
Review Article

The Neppe-Close triadic dimensional vortical paradigm: An invited summary

Vernon M Neppe* and Edward R Close

Abstract

Physicists are generally trained in the Standard Model of Physics (SMP). This implies that they perceive and account for only 3 dimensions of space in a moment in time (3S-1t) (a 4-dimensional [4D] model). However, applying the SMP, more than fifty significant conundrums have...

01/13/2020
Case Report

Occluded superior vena cava and failed epicardial pacing: An unorthodox solution

Ranjit K Nath* and Satyam Rajvanshi

Abstract

Permanent pacemaker implantation is conventionally done via upper limb veins. But in 1% - 6% cases, usual sub clavicular approach is either not possible or contraindicated due to complete occlusion of superior vena cava (SVC) or bilateral subclavian vein and/or bilateral impl...

01/13/2020
Case Report

Coronary-intercostal steal syndrome, a rare connection between the left circumflex coronary artery and intercostal arteries: A case report

Mohammed H Habib and Khaled H Alkhodari*

Abstract

A 60-year-old female patient presented with typical anginal pain on exertion and relieved by rest for about one month. Percutaneous coronary angiography was done and showed an abnormal left circumflex coronary artery connecting to intercostal artery. Embolization of that abno...

01/10/2020
Editorial

Retrosternal goiter mimicking asthma: A diagnostic challenge

Yiannakopoulou Eugenia*

Editorial

Asthma is a chronic respiratory disease characterized by chronic airway inflammation. Common manifestations of asthma include wheezing, chest tightness, cough, shortness of breath. Diagnosis of asthma requires clinical documentation of respiratory symptoms, exacerbation of s...

01/10/2020
Research Article

Oral Clindamycin and Metronidazole in the treatment of bacterial vaginosis in pregnant black women: Comparison of efficacy and pregnancy outcome

Ijeoma CC*, Nyengidiki TK, Bassey G, Ogu RN, Alegbeleye JO and Wariso KT

Abstract

Bacterial vaginosis (BV) is associated with adverse pregnancy outcomes with various treatment options.

Objective: To compare the efficacy and effect on pregnancy outcome of Metronidazole and Clindamycin in women with bacterial vaginosis in Port Harc...

01/09/2020
Research Article

An evaluation of hardness of commercially available provisional restorative materials: An in vitro study

Nimra Mehraj, Samarth Kumar Agarwal*, Romil Sinhal and Kanesha Abrol

Abstract

Statement of problem: Provisional restorations play a critical role in the success of restorative treatment so they must maintain their integrity in the oral environment throughout the diagnostic and restorative phases.

Purpose: The...

01/09/2020
Research Article

Effect of hemodialysis session on acute changes in inflammatory and cardiovascular risk biomarkers

Bernardo-Alio Lavin Gomez*, Maria-Teresa García Unzueta, Armando-Raul Guerra Ruiz, Sonia Perez San-Martin, Ana Berja, Natalia Fananas Rodriguez, Sara Diez Espejo and Domingo Gonzalez-Lamuno Leguina

Abstract

Background: Inflammation is associated with enhanced cardiovascular risk profile and increased cardiovascular mortality in end-stage kidney disease patients undergoing hemodialysis. Mechanisms of activated acute phase reaction in patients on chronic hemodialy...

01/08/2020
Review Article

A proposed mechanism to explain increases in intracranial pressure: The concept of cerebral artery wedge pressure

DR Hamilton*, A Mitha, MG Hamilton and JV Tyberg

Abstract

We hypothesize that, with elevated cerebral spinal fluid (CSF) pressure, cerebral micro-vascular obstruction and congestion may occur despite (subdural) large-vein pressures being normal. Smaller veins emptying into these larger, dura-enveloped veins are not immune to the com...

01/07/2020
Research Article

Radiofrequency vs. scalpel incision for upper blepharoplasty: A clinicopathologic and photo comparison

Juliana Senna Figueiredo Barbi*, Leonardo Diniz, Rodrigo Otavio do Espirito Santo, Icaro Perez Soares and Magda Pires

Abstract

Objective: The aim of this study is to compare scar appearance and the histopathological aspects of inflammatory response induced by the use of radiofrequency [RF] incision and a cold-blade scalpel incision in upper blepharoplasty surgery.

M...

01/06/2020
Case Report

A case study on Erdheim ‐ Chester Disease

Jakob Erdheim and Harald Koeck*

Abstract

In this brief essay, Harald Koeck offers an introduction to Professor Jakob Erdheim, an eminent pathologist of Vienna. Koeck is an independent researcher at different Pathology Departments (Department of Pathology St. Poelten with Prof. Hans Bank MD, Department of Pathology M...