09/20/2019
Research Article

Addition of Simvastatin to Carvedilol and Endoscopic Variceal Ligation improves rebleeding and survival in patients with Child-Pugh A and B class but not in Child Pugh C class

Sanjeev Kumar Jha*, Kuldeep Saharawat, Ravi Keshari, Praveen Jha, Shubham Purkayastha and Ravish Ranjan

Background: Even with current standard treatment after variceal bleeding which includes combination of nonselective b-blockers and repeated endoscopic variceal ligation, the risk of rebleeding and mortality are high. Statins exhibit an antifibrotic effect and improves HVPG. We...

09/26/2019
Research Article

Haemostasis with suture-tourniquet technique following removal of large-bore venous sheaths for endovascular recanalization of acute thrombosis in native arteriovenous fistula

Omur Balli*

Purpose: To investigate the suture-tourniquet technique for haemostasis in patients with acute thrombosis of native arteriovenous fistula (AVF) whom underwent manual aspiration thrombectomy using large-bore venous sheaths and high dose heparin.

Methods:

09/30/2019
Case Report

Automatic heartbeat monitoring system

Franchini Roberto*

The proliferation and popularity of open source hardware and software, such as Arduino and Raspberry PI, together with IoT and Embedded System, has brought the health industry to rapid evolution, creating portable and low-cost medical devices for monitoring vital signals. Electrocardiographic ...

09/24/2019
Case Report

A rare case of recurrent urinary tract infection due to Trichosporon species in an immune-competent diabetic female patient

Saroj Adhikari, Bhuvan Saud*, Govinda Paudel and Sunita Wagle

Trichosporonosis is a disease caused by Trichosporon spp. which are ubiquitous anamorphic yeast that commonly inhabit the soil. In human they are found in the skin, gastrointestinal tract and respiratory tract. Globally, Trichosporon spp. infection is rare and remain...

09/27/2019
Research Article

Screening of antibiotic residue in poultry in Kathmandu valley of Nepal: A cross-sectional study

Rajiv Sapkota*, Ramila Raut, Sujan Khanal, Muna Gyawali and Dipesh Sahi

This cross-sectional study was conducted to screen the presence of antibiotic residue in poultry. A total of 60 samples (30 Muscle and 30 Liver) were taken from local meat shops from different parts of Kathmandu valley. Disc assay method was used. Escherichia coli (ATCC 25922) and Staphylococc...

09/20/2019
Research Article

The association between hypoxia, chronic ischemia and alters prostate structure and progress of chronic prostatic disease

Mauro Luisetto*, Behzad Nili Ahmadabadi, Ghulam Rasool Mashori, Gamal Abdul Hamid

Chronic prostatitis today show high level of relapses and recurrent pathological events even if using the best pharmacological therapy. A better understanding of physiopathological effect of ischemic hypoxic condition (pelvic, prostate tissue) and the lymphatic congestion in same body region c...

09/19/2019
Research Article

Prevalence of disabling hearing loss in the elderly

Letícia Raquel Baraky Vasconcelos, Paula Ferraz Rodrigues, Paula Liziero Tavares and Audryo Oliveira Nogueira*

Abstract

Introduction: Disabling hearing loss refers to hearing thresholds superior than 40 dB in the better ear in the adults. The main cause of hearing loss in the elderly is the age-related hearing loss, also called presbycusis. This type of hearing impairment occu...

09/19/2019
Case Report

Occipital lobe ependymal cyst with unusual presentation

Okacha Naama*, Abdelilah Idir and Omar Boulahroud

Intraparenchymal cysts without communication to the ventricles or the subarachnoid space are named ependymal or epithelial cysts. The estimated ratio of their incidence compared with arachnoid cysts is 1:10. Neurologic deficit can occur when the cyst exerts mass effect on its surroundings. We ...

09/13/2019
Review Article

Avermectins: The promising solution to control plant parasitic nematodes

Mohamed S Khalil* and Dalia M Darwesh

Abamectin and emamectin are members of avermectin family which categorized as very effective but in the same time are toxic naturally. Most of products in this family are utilized as pharmaceuticals in both humans & animals and for crop protection.Despite avermectins are having complex chemica...

09/18/2019
Research Article

Low back pain induces disability of women in primary uncomplicated pregnancy

Panagiotis Korovessis*, Rania Antonaki, Spyridon Zacharatos and Vasileios Syrimpeis

Abstract

Study design: A consecutive case series study

Purpose: To investigate whether Low Back Pain (LBP) in women with primary singleton pregnancy induces disability.

Background: LBP is reported to be increased i...

09/04/2019
Review Article

Advances in the use of GABAergic interneurons for the treatment of epilepsy

Federica Frisina#, Giulia Valetti#, Giulia Zuccarini#, Luciano Conti# and Giorgio R Merlo*

Forebrain GABAergic neurons, the main inhibitory type of neuron in the cortex and hippocampus, represent a highly heterogeneous cell population that has been implicated in the predisposition to epilepsy and the onset of seizure. Earlier attempts to restore inhibition and reduce seizure in anim...

09/27/2019
Research Article

Glycemic status and its effect in Neonatal Sepsis - A prospective study in a Tertiary Care Hospital in Nepal

Badri Kumar Gupta*, Binod Kumar Gupta, Amit Kumar Shrivastava, Pradeep Chetri

Abstract

Introduction: Sepsis is an important cause of morbidity and mortality among neonates. Neonatal sepsis can alter the glucose level and both hypoglycemia and hyperglycemia may occur. A high or low blood glucose level may have a significant effect on the outcome...

09/03/2019
Research Article

Does it matter what a mother consumes? An anthropological exploration of dietary practices among Churachandpur (Manipur) pregnant women and its impact on infant birth weight

Evelyn Ngaithianven, JS Sehrawat* and Reetinder Kaur

Abstract

Background: Nutritional status of expectant women is an important indicator of healthy pregnancy and an ideal birth weight of the infant. The present study is an attempt to understand food eating practices and related taboos among the Paite women and whether ...

09/26/2019
Research Article

Prevalence of congenital heart diseases among primary school children in the Niger Delta Region of Nigeria, West Africa

Ujuanbi Amenawon Susan*, Tabansi Petronilla Nnena, Otaigbe Barbara Edewele

Introduction: Congenital heart diseases (CHD) are leading causes of childhood morbidity and mortality especially in developing countries. Community-based studies are important in ascertaining the burden of the disease.

Objectives: The study was set ...

09/24/2019
Research Article

Novel paclitaxel-coated balloon angioplasty via single retrograde popliteal access for challenging superficial femoral artery and iliac artery lesions?

Erdem Cetin*, Celal Selcuk Unal, Aydın Keskin, Hakan Kartal

Objectives: We report our results regarding the use of BioPath™ paclitaxel-coated balloon catheters for superficial or distal external iliac artery revascularization via single retrograde popliteal access.

Methods: We included 105 prospective cons...

09/20/2019
Research Article

Prediction of Left Ventricular Systolic Dysfunction after 6 months of Aortic Valve Replacement in patients with Chronic Severe Aortic Regurge

Ahmed S Ammar, Mohammad Gouda*, Mohammad Hassan

The natural history of chronic severe aortic valve regurgitation (AR) is characterized by a prolonged period of preserved global left ventricular (LV) systolic function and compensated eccentric hypertrophy, which insidiously gives way to myocardial decompensation [1].In its early stages, myoc...

09/20/2019
Research Article

Arrhythmia of the heart - computer analysis

VI Kaganov*

The problem of synchronization of oscillations of various physical nature is discussed. From the standpoint of the theory of synchronism, a model of the heart is considered as a system of four connected between self-oscillating links: two atria and two ventricles. The synchronous and asynchronous...

09/27/2019
Research Article

Results of chemotherapy in the treatment of chronic lymphoid leukemia in Black Africa: Experience of Côte d’Ivoire

N’dhatz Comoe Emeraude, Packo Dieu-le-veut Saint-Cyr Sylvestre*, Nanho Danho Clotaire, Bognini Sarah, Kamara Ismael, Boidy Kouakou and Koffi Kouassi Gustave

Background: The treatment of chronic lymphoid leukemia currently uses news drugs which are more expensive in our countries. Its why, the results of chemotherapy remains a challenge in our sector.

Aims: To evaluate the place of polychemotherapy in th...

09/18/2019
Review Article

A mouse model of coronary microvacsular disease using a photochemical approach

Xinlu Wang, Fang Liu and Zhen W Zhuang*

The development of reproducible rodent models of coronary microvascular disease (MVD) is essential for the early detection, treatment, and mechanism study of the pathophysiology. We hypothesized that endothelial dysfunction and subsequent microthrombi in the coronary arterioles, two early even...

09/13/2019
Case Report

Anomalies of coronary artery origin: About two cases

Dioum M*, Sarr EM, Manga S, Mingou JS, Diack A, Diop AD, Bindia D, Diagne PA, Sarr AN and Diop IB

Anomalies of coronary artery origin are congenital malformations characterized by the abnormal birth of a coronary artery from the controlateral coronary aortic sinus (birth of the left coronary artery from the right sinus or birth of the right coronary artery from the left sinus).The artery c...

09/03/2019
Research Article

How often is Klippel-Feil Syndrome associated with congential heart disease presentation of five cases and a review of the literature

Ramush Bejiqi, Ragip Retkoceri, Arlinda Maloku, Rinor Bejiqi, Aferdita Mustafa, Faruk Husremovic and Samir Bejic*

Introduction: Klippel-Feil syndrome (KFS), is a bone disorder characterized by the abnormal joining (fusion) of two or more spinal bones in the neck (cervical vertebrae), which is present from birth. Three major features result from this abnormality: a short neck, a limited ra...

09/18/2019
Research Article

Effect of laparoscopic salpingectomy on subsequent ovarian response after controlled ovarian hyperstimulation

Chadi Yazbeck*, Asma Boukadida, Christian Chauvin, Anne Laure Margulies and Segolene Falcone

Abstract

Background: The effect of salpingectomy on ovarian response is a matter of debate. Due to conflicting data, alternative techniques were developed to perform salpingectomy for treatment of hydrosalpinges in infertile patients. This study aims to evaluate the e...

09/24/2019
Research Article

Novel paclitaxel-coated balloon angioplasty via single retrograde popliteal access for challenging superficial femoral artery and iliac artery lesions?

Erdem Cetin*, Celal Selcuk Unal, Aydın Keskin and Hakan Kartal

Objectives: We report our results regarding the use of BioPath™ paclitaxel-coated balloon catheters for superficial or distal external iliac artery revascularization via single retrograde popliteal access.

Methods: We included 105 prospective cons...

09/11/2019
Research Article

The validity of progesterone level on hCG injection day in the prediction of IVF/ICSI cycles’ outcome

Mostafa A Abolfotouh*, Hallah Al-Anazi and Samar Hassan

Abstract

Background: Previous studies highlighted the negative effect of premature progesterone elevation (PE) during IVF cycles on the cycle outcomes. The aim of this study was to assess the validity of progesterone level on hCG day (P4) in the prediction of IVF/ICSI...

09/09/2019
Research Article

An evaluation of visual outcome of corneal injuries in a tertiary care hospital

Aarudhra Premchander, Seema Channabasappa, Nischala Balakrishna* and Neha Nargis

Background: Corneal injuries are significant contributors to blindness. Cornea being the most anterior structure of eye is exposed to various hazards like airborne debris and blunt trauma. By understanding different types of injuries to which cornea is exposed, the practitioner m...

09/02/2019
Case Report

Weight loss counseling for dialysis patients to prepare for transplant

Karen F Factor*

Obesity has become a worldwide Epidemic affecting more than 300 million people. Overweight is defined as BMI (Body Mass Index) of 25-29.9 kg/m2. Obesity is defined as BMI greater than 30 kg/m2, and Morbid Obesity is a BMI of > than 35 kg/m2 [1].

Many Dialysis patients are overweight...

09/12/2019
Case Report

A case report of an Erdheim-Chester patient focused on pain management

Jose Osvaldo Barbosa Neto*, Joao Batista Santos Garcia, Thiago Alves Rodrigues and Camila Freitas de Andrade Rodrigues

Introduction: Erdheim-Chester disease (ECD) is a rare and diffi cult-to-treat non-Langerhans cell histiocytosis characterized by the excessive production and accumulation of histiocytes. This study reports a case of ECD, emphasizing both its diagnosis, assessment and treatment...

09/06/2019
Research Article

Outcome of laparoscopic varicocelectomy with mass ligation technique for symptomatic varicocele

Sardar Rezaul Islam*, Majedul islam, Shah Alam Sarkar and Shah Paran

Abstract

Background: Varicocele therapy is a controversial issue. No single approach is adopted as the best therapeutic option. Testes get blood supply from testicular artery, cremasteric artery and artery to the vas deference. So ligation of testicular artery in the ...

09/06/2019
Review Article

Extremely large hemangioma of the liver: Safety of the expectant management

Subhi Mansour, Sharbel Khouri, Maisa Andraous and Safi Khuri*

Hemangiomas are known as congenital vascular malformations that can affect almost any organ or tissue, with the liver being the most common intra-abdominal organ to be involved. It is well known that hemangiomas are the most common benign tumours of the liver, and develop in about 4-20% of peo...

09/02/2019
Review Article

Essential thrombocythemia: Biology, clinical features, thrombotic risk, therapeutic options and outcome

Vincenzo Accurso*, Santoro M, Contrino AD, Casimiro P, Raso S, Carlisi M, Sardo M, Perez A, Di Piazza F, Russo A and Siragusa S

Essential Thrombocythemia (ET) is currently classified as a Philadelphia negative myeloproliferative neoplasm (MPN) together with polycythemia vera (PV) and primary myelofibrosis (PMF); the latter can be further divided in pre-fibrotic primary myelofibrosis (pre-PMF) and overt myelofibrosis, a...