11/29/2019
Clinical Image

Branchio Oculo Facial Syndrome

Maha Oudrhiri*, Toualouth L, Houda Oubejja, Fouad Ettayebi and Hicham Zerhouni

Clinical Image

A 3-month-old girl presented to the surgical consultation room with bilateral cleft lip incomplete. A girl weighing 4205 g, was born at term  after an uneventful pregnancy with a birth weight of 2500 g. There was no family history. On examination, a congenital, lin...

11/29/2019
Research Article

Patients’ satisfaction and associated factors towards nursing care in Dessie Referral Hospital, Northeast Ethiopia

Afework Edmealem*, Yabebal Asfaw, Sewunet Ademe and Belachew Tegegne

Abstract

Introduction: A patient satisfaction is considered as one of the desire outcomes of health care and it is directly related with utilization of health services. However, its level is falls at the fundamental level in developing countries including Ethiopia.

11/27/2019
Short Communication

Modeling of A.I based Inhalation for Advanced Life Support System Development

Md. Sadique Shaikh* and Tanvir Begum

Abstract

Present piece of idea exhibits to divert attention towards automated high precision Life Support System (LSS) instead of manual one using medical intelligence devices while treating and diagnosis to the patient, where Ventilator, inhaler and respiratory control is most import...

11/27/2019
Research Article

Biodegradation of gold and platinum implants in rats studied by electron microscopy

Hendrik Kosslick, Hermann Sauer, Tino Just, Ursula Vick, Gerhard Fulda and Ludwig Jonas*

Abstract

Biodegradation of implanted gold in human tissue. TEM images reveal markedly biodegradation of implanted gold and re-crystallization of dissolved gold as nanoparticle of different size, shape and crystallinity. Highly crystalline icosahedral Au nanoparticle and the correspond...

11/27/2019
Research Article

Gaucher’s disease and liver involvement: A review and our experience

Vitantonio Guglielmi*, Mario Correale and Gioacchino Leandro

Abstract

Background: This article reviews current knowledge of Gaucher’s disease (GD) and liver involvement and reports our experience: how many patients with chronic liver disease of unknown origin could be affected by Gaucher’s disease.

11/27/2019
Research Article

Innovative results in the treatment of inespecific anusitis-proctitis with the use of bergamot gel (Benebeo gel)®

Danilo Cafaro, Felipe Celedon, Alessandro Sturiale and Stefania Sinicropi*

Introduction

Inflammation is a complex biological reaction induced by the alteration of tissue homeostasis, which occurs in response to the presence of a biological, chemical or physical agent in the body [1]. The acute inflammatory response is composed of an elaborate cascade of both...

11/26/2019
Prospective

Recent approach to incorporate tellurium in metal carbonyl cluster utilizing extrusion reaction

Pradeep Mathur* and Ajeet Singh*

Abstract

The incorporation of tellurium into metal carbonyl using tellurium transfer/ extrusion reaction is presented in this work. The results bring one of the new ways to incorporate tellurium by transferring it from one molecule to another molecule, in comparison to the work so far...

11/26/2019
Research Article

Long-Term Impact of Coronary Artery Disease in Lung Transplantation

William S Ragalie, Nilto C de Oliveira, Richard Cornwell, Keith Meyer and James D Maloney*

Background: Adoption of the Lung Allocation Score (LAS) has led to increased listing of older patients and those with idiopathic pulmonary fibrosis (IPF) for lung transplantation (LTX). Older patients and those with IPF have higher prevalence of coronary artery disease (CAD), a r...

11/26/2019
Research Article

Readjustment of antithrombotic therapy in stroke-patients owing to transesophageal echocardiography findings

Toralf Bruening* and Mohamed Al-Khaled

Objectives: Cardioembolic etiology is a frequent source of ischemic stroke. Echocardiogram is the mainstay of cardioembolic source detection with regard to plan secondary stroke management, however it remains unclear how often clinically actionable findings are provided hereby. I...

11/25/2019
Case Report

Resolved complete atrioventricular block and left ventricular severe dysfunction in patient with Wegener’s granulomatis after cyclophosphamide and corticosteroid treatment

Duc Dang*, Lory Trevisan, Jérôme Bouet and Jérôme Taieb

Introduction

Wegener’s granulomatosis is a systemic granulomatous focus on small to medium sized vessels. It typically affects sinuses, lungs and kidneys due to necrotizing granulomatous vasculitis. Less commonly, cardiac involvement is reported up to 8%-44% of cases [1-3]. It o...

11/20/2019
Research Article

The Renin-Angiotensin System: Alamandine is reduced in patients with Idiopathic Pulmonary Fibrosis

Taís Salvi Sipriani, Robson Augusto Souza dos Santos and Katya Rigatto*

Abstract

Idiopathic Pulmonary Fibrosis (IPF) is a chronic and progressive disease without treatment that leads to death. Therefore, to control its progression to pulmonary hypertension is still a challenge. Moreover, there is no study that has investigated the Renin-Angiotensin System...

11/22/2019
Research Article

Correlation between the presence of maternal gestational or pre-gestational pathologies and hearing impairment in the puerperal period

Raphaella Costa Moreira Simen*, Alan Araújo Vieira, Maria Elisa Vieira da Cunha Ramos Miterhof and Armanda de Oliveira Pache de Faria

Abstract

Objective: To evaluate whether the occurrence of maternal pathologies, mainly Diabetes Mellitus and Hypertensive Syndromes in the gestational or pre-gestational period may be related to hearing impairment in postpartum women.

Methods:

11/21/2019
Case Report

First trimester growth delay: An early marker of triploidy

Sydney M Thayer*, Rachel A Pilliod, Emmanuelle Pare, Amber Vandehey, Hannah Raszka, Kelly Thomas and Rinathia Hachmon

Introduction

Triploidy is one the most common chromosomal abnormality in humans, complicating about 1% of all human pregnancies. Most affected conceptions undergo spontaneous abortion in the first trimester, making the prevalence of second trimester triploidy low. Viable triploidy is ...

11/25/2019
Case Report

Lateral Pedicle and Connective Tissue Graft – A combined approach for management of isolated gingival recession

Ramnath Elangovan*, Ramakrishnan Theyagarajan, Ebenezer Mani and Mejalla Muthiah Amaladhas

Abstract

Gingival recession is defined as apical migration of the gingival epithelium leading to the exposure of root surface. There are many surgical procedures for treating gingival recessions and the main goal is to cover the exposed tooth surface by soft tissue augmentation. The s...

11/21/2019
Case Report

Cranio-Facial Fibrous Dysplasia: A case report of a conservative treatment in a monostotic form associated with an orthodontic management and a bone graft of the non-lytic bone area for dental implant rehabilitation

Seban A*, Blein E, Perez S and Seban B

Abstract

Fibrous dysplasia is an osteolytic lesion in which bone is replaced by an instable fibrous osseous tissue. The aim of this case report is to highlight dental rehabilitation (bone grafts to allow dental implant) on patients suffering of this condition.

A 39-year-old ...

11/27/2019
Research Article

Perceived causes and prevention of catheter-associated urinary tract infections among spinal cord injured patients

Malomo Adefolarin O*, Aminu, Kafayat, Adeolu Augustine A, Adeleye Amos O, Balogun James A, Badejo Oluwakemi A, Shokunbi Mathew T and Jegede Ayodele S

Summary

Catheter-associated urinary tract infection (CAUTI) is among the most common nosocomial infections especially in acute care settings. Its economic and unanticipated health implications make it burdensome for the healthcare providers and patients. The paper examined the perceiv...

11/22/2019
Research Article

Effect of intradialytic physical activity on the quality of life, biological parameters and sleep in hemodialysis patients

Mélanie Gallot, Nathalie Rieth and Alexandre Ganea

Abstract

Many side effects, in addition to those of the pathology itself, have occurred with hemodialysis treatment but existing literature have shown that physical activity is beneficial to hemodialysis patients. Nevertheless, our parameters have not been studied enough with a resist...

11/20/2019
Case Report

Diabetes and chronic kidney disease: a rare cause for a very common association

José Agapito Fonseca*, Sofia Jorge, Joana Gameiro, José António Lopes and José Oliveira Guerra

Abstract

The authors present the case of a 45-year-old female patient with diabetes and chronic kidney disease (CKD). She had unsatisfactory glycemic control, and showed some intellectual limitations. Her urine exam was unremarkable, and her renal ultrasound revealed single right kidn...

11/20/2019
Research Article

Acute Appendicitis: Hispanics and the Hamburger Sign

Garcia Gubern C, Colon Rolón L, Ruiz Mercado I, Oliveras Garcia C, Caban Acosta D, Muñoz Pagán J, Iriarte I, Bolaños Ávila G Peguero Rivera J, Sánchez Gaetan F, Oneill Castro J, Cordero Colón Paola N, Garcia-Colon Carlos A and Romero-Vazquez Ana M*

Abstract

Objective: To describe the presenting clinical findings of patients with acute appendicitis and compare them with those described in the medical literature. To corroborate a common medical myth among Hispanic physicians regarding the presentation of acute app...

11/20/2019
Letter to the Editor

Hot cholecystectomy

Esam Aboutaleb*

Letter to Editor

Acute cholecystitis is a common general surgery disease which may require hospital admission. Delayed or early cholecystectomy is the definitive treatment. Availability of theatre slots may postpone cholecystectomy for weeks. I am writing this letter to explain the im...

11/20/2019
Research Article

Only low intensity of aerobic exercise improves respiratory compliance in pulmonary hypertensive rats

Katya Rigatto*, Denielli Da SG Bós, Renata Fernandes, Rodrigo B Jaenisch and Pedro Dal Lago

Abstract

Objective: To investigate in an animal model of Pulmonary Hypertension (PH) by monocrotaline whether a lower exercise intensity, which has lower potential to provoke dyspnea symptoms, could prevent the increase the right ventricle pressure and the decrease in...

11/20/2019
Case Report

Foley catheter balloon tamponade as a method of controlling iatrogenic pulmonary artery bleeding in redo thoracic surgery

Marcus Taylor*, Muhammad Asghar Nawaz, Ozhin Karadakhy, Denish Apparau, Kandadai Rammohan and Paul Waterworth

Background: Pulmonary artery bleeding secondary to iatrogenic injury is a troublesome intraoperative complication. The likelihood of encountering this complication is significantly higher in redo surgery for a number of reasons, including distortion of anatomical structures, a...

11/20/2019
Case Report

Treatment of autoimmune hemolytic anemia with erythropoietin: A case report

Juan P Ovalle, Estefanía M Orozco, Laura C Pedraza, María C Barrera, Renato A Guzmán* and Dormar D Barrios M

In this article, we describe the case of a fifty-year-old patient with autoimmune hemolytic anemia (AIHA) with constitutional symptoms, jaundice, unquantified fever and progressive dyspnea. The patient had history of smoking and Hepatitis A and following a physical exam she was found in a regu...

11/19/2019
Case Report

Patellar fractures in children

Mohammed Shabeer*, Nasir Muzaffar and Sameh Abdalla

We describe a rare case of patellar fracture in a seven year old girl. The case was reviewed for various aspects such as clinical diagnosis, imaging tests and most suitable treatment.

11/11/2019
Research Article

Immunohistochemical expression of Nestin as Cancer Stem Cell Marker in gliomas

Rasha Mokhtar Abdelkareem*, Afaf T Elnashar, Khaled Nasser Fadle and Eman MS Muhammad

Abstract

Background: Gliomas represent the most frequent primary tumors of central nervous system (CNS), contributing to more than half of the incidence of brain tumors. Cancer stem cell markers (CSC) identify a group of patients at high risk for progression. Nestin i...

11/13/2019
Research Article

Evaluation of outcomes of 8-week therapy with ledipasvir/sofosbuvir or glecaprevir/pibrentasvir in veterans with hepatitis C infection

L Anri Lemoine and Marisel Segarra-Newnham*

Summary

Hepatitis C Virus (HCV) infection is usually treated with direct acting antivirals (DAAs) for 12 weeks. In treatment naive patients with genotype (GT) 1 infection without cirrhosis and baseline viral load <6 million, 8 weeks of Ledipasvir/Sofosbuvir (LDV/SOF) is an option. ...

11/15/2019
Research Article

Left ventricular ejection fraction and contrast induced acute kidney injury in patients undergoing cardiac catheterization: Results of retrospective chart review

Firas Ajam, Obiora Maludum, Nene Ugoeke, Hetavi Mahida, Anas Alrefaee, Amy Quinlan DNP, Jennifer Heck-Kanellidis NP, Dawn Calderon DO, Mohammad A Hossain* and Arif Asif

Abstract

Background: Contrast-induced acute kidney injury (CI-AKI) is an important cause of increasing the hospital stay and in-hospital mortality. By increasing intra-renal vasoconstriction, left ventricular ejection fraction (LVEF) can increase the risk of CI-AKI. W...

11/15/2019
Case Report

Hemoptysis after subclavian vein puncture for pacemaker implantation: A case report

Avishek Bagchi, Rajendra Kumar Agarwal and Kewal Kishan Talwar*

Abstract

Background: Subclavian venous access for pacemaker lead insertion is a common procedure and is normally considered safe in the hands of an expert. However, subclavian venepuncture is not without complications, starting from mild subcutaneous hematoma to pneum...

11/11/2019
Research Article

Correlation of plasma protein from MDS, young and elderly patients by SDS-page

Nathanielly de Lima Silva, Danilo Nobre, Josiel Nascimento dos Santos, Márcia Santos Rezende, Lúcio Henrique Sousa Pinheiro, Carlos Arthur Cardoso Almeida and Dulce Marta Schimieguel*

Abstract

Summary: Myelodysplastic Syndrome (MDS) is a heterogeneous group of clonal hematopoietic malignancies characterized by progressive cytopenias, ineffective hematopoiesis, bone marrow hypercellularity and transformation to acute myeloid leukemia (AML).

<...

11/12/2019
Opinion

States Care - The Cure for Patient Healthcare

Deane Waldman*

Opinion

Clinical physicians believe they are drowning . . . because they are! Between complying with an ever-changing landscape of time-wasting federal regulations, avoiding Health Insurance Portability and Accountability Act violations, plus the entire billing process, who can keep u...

11/15/2019
Review Article

Alcoholism and its implications for the dental team, an update and review of the literature

Vignesh Eswara Murthy*

Abstract

Precis: This Literature review is intended to provide dental practitioners with an update of the implications that Alcoholism poses to them.

Statement of the problem: Alcoholism raises several distinct problems for dental profession...

11/15/2019
Editorial

Pulse Synchronized Contractions (PSCs)

Katherine A Lothman* and Allen W Mangel

Editorial

A key platform underpinning the traditional understanding of the cardiovascular system, with respect to the behavior of large arterial vessels, is Otto Frank’s Windkessel Hypothesis [1]. This hypothesis posits simply that the smooth muscle walls of large arteries do no...

11/08/2019
Research Article

Incidence of hypertension in a high-risk workgroup (Police officers) - Observational study

Guillermo Padrón Arredondo*

Summary

Introduction: Hypertension is a silent pathology in a way that affects all four spheres to be considered as such; magnitude, transcendence vulnerability, and feasibility. The World Health Organization estimates that 45% of deaths from heart disease and 51% of ...

11/08/2019
Short Communication

Human mesenchymal stem cells conditioned media promotes the wound healing process - An in vitro study

Rashi K Jain*, Devashree Vakil, Corey Cunningham and Kuldip Sidhu

Abstract

Mesenchymal stem cells (MSCs) conditioned medium (CM) has a promising prospect towards skin regeneration. Therefore, human dental pulp and adipose stem cells (DPSCs and ADSCs) were isolated, propagated and evaluated for their stemness and genetic stability over time in cultur...

11/05/2019
Review Article

Drug abuse and its ramifications on skeletal system

Das Sanjita* and Kumar Naveen

Abstract

The purpose of this study is to highlight the drug abuse hazards and preventive aspects. From a public health perspective, substance abuse has long been a source of major concern, both for the individual’s health and for wider society as a whole. The UK has the highest ...

11/01/2019
Opinion

Biological membranes: The laboratory of fundamental physics

Samo Kralj* and Mitja Kralj

Opinion

Biological membranes present an essential constituent of living cells. Their main role is to separate the interior of a cell from its surrounding, however allowing the selective transfer of specific material through it. Configuration changes of membranes are often correlated w...

11/04/2019
Research Article

A Systematic review for sudden cardiac death in hypertrophic cardiomyopathy patients with Myocardial Fibrosis: A CMR LGE Study

Sahadev T Reddy, Antonio T Paladino, Nackle J Silva, Mark Doyle, Diane A Vido and Robert WW Biederman*

Abstract

Background: Hypertrophic cardiomyopathy (HCM) patients have a predisposition for malignant VT/VF and consequently, sudden cardiac death (SCD). In single center studies, late gadolinium enhancement (LGE) defined fibrosis has been linked to VT/VF. However, desp...

11/04/2019
Review Article

Do beta adrenoceptor blocking agents provide the same degree of clinically convincing morbidity and mortality benefits in patients with chronic heart failure? A literature review

Martin Mumuni Danaah Malick*

Abstract

Chronic heart failure has been extensively characterized as a disorder arising from a complex interaction between impaired ventricular performance and neurohormonal activation. Since beta adrenoceptor blocking agents are currently considered an integral component of therapy f...

11/01/2019
Research Article

Anthropometric characteristics and somatotype of professional soccer players by position

Cavia MM*, Moreno A, Fernández-Trabanco B, Carrillo C and Alonso-Torre SR

Abstract

The anthropometric characteristics are decisive for an optimal physical level and, therefore, a good level in the game; and they can be different depending on the game position.

The aim of this study was to identify the physical characteristics, body composition and...

11/04/2019
Review Article

Protection from the Pathogenesis of Neurodegenerative Disorders, including Alzheimer’s Disease, Amyotrophic Lateral Sclerosis, Huntington’s Disease, and Parkinson’s Diseases, through the Mitigation of Reactive Oxygen Species

Samskruthi Madireddy* and Sahithi Madireddy

Abstract

The biological changes caused by oxidative stress (OS) are known to be involved in the etiology of neurodegenerative disorders, including Alzheimer’s disease, amyotrophic lateral sclerosis, Huntington’s disease, and Parkinson’s disease. The brain is particul...

11/06/2019
Case Report

A unique case of metastatic spinal epidural abscess associated with liver abscess following ascending cholangitis and Escherichia coli bacteremia

Nour Karra#, Samer Ganam#, Amitai Bickel, Maxim Bez, Ibrahim Abu Shakra, Doron Fischer and Eli Kakiashvili*

Abstract

Pyogenic liver abscess (PLA) is a life-threatening infection that may develop as a result of an underlying hepatobiliary disease. A possible complication of PLA is metastatic spread, resulting in distant seeding of infection in other organs, and occasionally in the epidural s...

11/04/2019
Research Article

Diagnosis of critical congenital heart defects in Iceland 2000-2014

Hallfríður Kristinsdóttir, Þórður Þórkelsson, Hildur Harðardóttir and Gylfi Óskarsson*

Abstract

Critical congenital heart defects (CCHDs) are preferably diagnosed prenatally or soon after birth. Late diagnosis has been related to poorer prognosis. The aim of this study is to assess when CCHDs are diagnosed in Iceland and whether late diagnosis is a problem. All live bor...