12/31/2019
Opinion

Obesity-Treatment by drugs

Sahithi G*

Opinion

The main disturbing situation faced by any individual is obesity nowadays. Obesity occurs because of overweight and this has several reasons to gain weight like hereditary, diabetes, diet, aging, PCOS in women, stress, and tiredness. It is a major, sustaining, worsening condit...

12/31/2019
Research Article

The importance of gestational age in first trimester, maternal urine MALDI-Tof MS screening tests for Down Syndrome

Ray K Iles*, Nicolaides K, Pais RJ, Zmuidinaite R, Keshavarz S, Poon LCY and Butler SA

Abstract

Background: The proposal that MALDI-ToF mass spectrometry could be used as a direct, rapid and affordable diagnostic tool in clinical laboratory medicine has moved from a theoretical possibility to a reality for Microbiology. Several studies have proposed the...

12/31/2019
Research Article

Burden of hearing loss in Subsaharan Africa: Snapshot from an ENT clinic in Nigeria

Ogunkeyede SA*, Adebola SO, Daniel A and Adeyemo AA

Summary

Background: Disabling hearing loss is a prevalent public health issue, with significant impact on patients’ communication. The disability associated with hearing loss depends on the severity of the hearing loss. There are limited rehabilitative measures ...

12/17/2019
Clinical Image

A rare case of abdominal pain and hematuria from retroaortic left renal vein

Perez J* and Pozo D

Clinical Image

A 62-year-old female with a history of arterial hypertension, attended the emergency department due to pain in the left flank. On physical examination no showed signs of peritoneal irritation. Urinalysis was indicated, that reported microscopic hematuria and negative ab...

12/30/2019
Research Article

Potential of Pleurotus sajor-caju compost for controlling Meloidogyne incognita and improve nutritional status of tomato plants

Doaa M Mostafa, Sherin FA Awd Allah* and Eman FA Awad-Allah

Abstract

The potential of spent compost of oyster mushroom, Pleurotus sajor-caju cultivated on rice (MCR) or wheat straws (MCW) was evaluated against the root-knot nematode, Meloidogyne incognita on tomato plants under field conditions during two successive seasons (2016 and 2017). Th...

12/30/2019
Research Article

Evaluation of the effect of coronary artery bypass grafting on the right ventricular function using speckle tracking echocardiography

Mahmoud Shawky Abdelmoneum, Neama Ali Elmeligy, Elsayed Abdelkhalek Eldarky and Mohamad Mahmoud Mohamad*

Abstract

Purpose: This was a prospective study conducted at Benha University hospital and National Heart Institute on one hundred patients undwent coronary artery bypass grafting (CABG) to evaluate the effect of CABG on the right ventricular (RV) function using speckl...

12/30/2019
Case Report

Parry-Romberg syndrome: A case report of non-invasive treatment

Anahita Dehghani Soltani, Azita Tehranchi, Shiva Safari, Zahra Tehrani and Samin Ghaffari*

Abstract

Parry-Romberg syndrome is an uncommon condition, self-limiting with slow progressive hemifacial atrophy. This syndrome can lead to several progressive congenital and developmental deformities. It can cause severe facial asymmetry and subsequently lead to esthetic and psycholo...

12/27/2019
Research Article

Nutritional analysis of Sphenostylis Stenocarpa seeds partially included with soya bean meal in Heterobranchus Bidorsalis fingerling diet

Oluwaseyi Yanmife Mogaji*, Lenient Mercy Onivie Ibiyo and Felicia Oluwatoyin Joshua

Abstract

Five experimental feeding trials were conducted to investigate the performance of Heterobranchus bidorsalis fingerlings to graded levels (0, 25, 50,75 and 100%) of Sphenostylis stenocarpa seed meal diets. Complete randomized design with triplicate groups of fingerlings was us...

12/27/2019
Research Article

Beginnings of bariatric and metabolic surgery in Spain

Aniceto Baltasar*

Overview

Bariatric Surgery (BS) from the Greek bari = weight and iatrein = cure) treats obesity and began in Spain in 1973. Its greatest development occurs after the founding of SECO (Spanish Society of Obesity Surgery) in 1997. The purpose of this work is to reflect the changes that ...

12/24/2019
Research Article

The effect of a European-based exercise program upon the health-related physical fitness of individuals with intellectual disabilities: The alive and kicking perspective

Skordilis Emmanouil*, Greenlees Iain, Chrysagis Nikolaos, Grammatopoulou Eirini, Arriaga Andres, Vaquero Fernandez Almudena, Gaillard Joel, Skordilis Antonios, Dias Joao, Papadopoulou Vassiliki and Serras Dionysios

Abstract

The present study examined the effect of the European-Based ‘Alive and Kicking’ exercise program on the health-related physical fitness of individuals with (Experimental Group: EG) and without (Control Group: CG) (Intellectual Disability: ID). The Self-Determinati...

12/24/2019
Research Article

Pregnancy and childbirth in women aged 40 and over at befelatanana maternity, Madagascar

Rakotomalala Nivoarimelina Zoly*, Rakotozanany Besaina, Razafindraibe Andriatompoina Felanarivo, Ramarokoto Malalafinaritra Patrick Marco, Rafamatanantsoa Jean Florent, Kapche Wato Edith and Randriambololona Domoina Malala Aurelia

Abstract

Objective: Pregnancy after age 40 remains a concern as it exposes to particular obstetrical complications. Our study aims to determine the risks of complications related to pregnancy and childbirth of women aged 40 and over.

Study design:

12/23/2019
Case Report

Orgasmic coitus triggered stillbirth via placental abruption: A case report

Márta Zsoldos, Márton Vezér, Henriette Pusztafalvi, Bianka Pencz, Dora Hargitai and Attila Pajor*

Summary

Sexual activity during healthy pregnancy is safe. There are little data on how coital activity affects outcome of the high-risk pregnancies. Hereby we report a case demonstrating that orgasmic coitus triggered placental abruption resulting in preterm stillbirth.

A 38...

12/31/2019
Research Article

Synthesis of Carbon Nano Fiber from Organic Waste and Activation of its Surface Area

Brijesh Gaud, Amrita Singh, Sandesh Jaybhaye and Himanshu Narayan*

Abstract

Carbon Nano fibers (CNFs) have recently attracted a lot of attention due to their widespread range of technological applications attributed to their unique physical and chemical properties, such as, small size, high strength, high adsorption linked with their large specific s...

12/18/2019
Mini Review

Could metabolic risk factors contribute to the development of cervical cancer?

Maydelín Frontela-Noda*, Eduardo Cabrera-Rode, Maite Hernández-Menéndez and Raquel Duran-Bornot

Abstract

The role of human papillomavirus infection as etiological factor for cervical squamous intraepithelial lesions and cervical cancer is well established. However, the presence of this virus is not sufficient condition for developing of cervical cancer. Currently, the contributi...

12/23/2019
Research Article

Snake envenomation during pregnancy

Denisse Martínez and Newton G Osborne*

Abstract

Background: We report our experience with management and treatment of pregnant women who were admitted at our institution for snake envenomation.

Methods: We reviewed the charts and recorded the management, treatment, and outcome of...

12/19/2019
Research Article

Theoretical study on binding interactions of laccase-enzyme from Ganoderma weberianum with multiples ligand substrates with environmental impact

Yosberto Cárdenas-Moreno*, Luis Ariel Espinosa, Julio Cesar Vieyto, Michael González-Durruthy, Alberto del Monte-Martinez, Gilda Guerra-Rivera and Maria Isabel Sánchez López

Abstract

Laccase catalyzes oxidation of lignin and aromatic compound with similar structure to this one. Their low substrate specificity results on degradation of similar phenolic compounds. In this context, Molecular Docking was performed with different ligands suggesting potential b...

12/18/2019
Review Article

A review on the occurrence of opportunistic infections after applications of stem cell techniques

Hasan Hosainzadegan*, Parviz Vahedi and Mortaza Hosainzadegan

Abstract

In recent years, stem cells technology have been used widely in basic and clinical science researches LIPUS (low-intensity pulsed ultrasound) is another technique commonly used in conjunction with stem cells that can have complications after applications. One of the important...

12/17/2019
Research Article

Comparative effect of calcium supplementation on the incidence of pre-eclampsia and eclampsia among primigravid women

Assontsa Kafack Carole*, Essiben Felix, Tumasang Florence, Meka Esther Juliette, Tongo Sedrick Fofack and Mbu Robinson Enow

Abstract

Background: Pre-eclampsia is a frequent and serious pregnancy complication contributing for the increasing maternal morbi-mortality rates. This study was designed to evaluate the effect of calcium supplementation during pregnancy, on the incidence of pre-ecla...

12/17/2019
Clinical Image

Cytomegalovirus infection in native kidney biopsy

Raquel M Moreira, Géssica SB Barbosa*, Cristiane B Dias, Luis Yu, Viktoria Woronik and Lívia B Cavalcante

Text

A 61-year-old Brazilian black woman consulted with a nephrologist due to proteinuria identified on a routine urine test. She has a personal history of thymoma resection five years ago, followed by multiple episodes of pulmonary infections including mycobacteriosis, recurrent muco...

12/12/2019
Research Article

Nematicidal effect of abamectin, boron, chitosan, hydrogen peroxide and Bacillus thuringiensis against citrus nematode on Valencia orange trees

MAM El-Saedy, Sandy E Hammad and Sherin FA Awd Allah*

Abstract

The nematicidal efficacy of abamectin, boron, chitosan, hydrogen peroxide, Bacillus thuringiensis and oxamyl 24% SL against citrus nematode, Tylenchulus semipenetrans were examined on Valencia orange trees under field condition for two successive seasons (2017 and 2018). The ...

12/12/2019
Research Article

Dry eye syndrome: Therapeutic challenges and future trends

Irami Araújo-Neto, Amália Cinhtia Meneses Rêgo and Irami Araújo-Filho*

Abstract

Introduction: Intense Pulsed Light (IPL) is the therapeutic tool implemented in the treatment of dry eye, characterized by the emission of waves of 500-1200nm in the region of the upper and lower eyelids. Dry eye is a recurring complaint in ophthalmology offi...

12/11/2019
Letter to the Editor

Evaluation in real life of the impact of photo-protection counseling in patients with actinic keratosis

Khaled Ezzedine, Sophie Seité and Charles Taïeb*

Dear Editor

Actinic keratosis (AK) are scaly lesions caused by chronic ultraviolet-induced damage to the epidermis which are a proxy for excessive sun-exposure [1] that may evolve into squamous cell carcinoma [2-7]. Therefore,&nbs...

12/05/2019
Case Report

Localized intrapulmonary desmoplastic mesothelioma: A case report

Meng Liu, Kaifu Wu and Yongming Tan*

Abstract

Introduction: Desmoplastic Malignant Mesothelioma (DMM) is a rare histological subtype of sarcomatoid malignant mesothelioma arising most frequently in the pleura or peritoneum and less frequently in the lung parenchyma.

Patient concerns:

12/06/2019
Letter to the Editor

Achievement of cure following allogeneic HSCT with Flu-Bu regimen in a patient with severe mycosis fungoides and Sezary Syndrome

Mahmut Yeral*

Letter to Editor

Experience with allogeneic hematopoietic stem cell transplantation (HSCT) in mycosis fungoides/Sezary syndrome (MF/SS) is limited to a small number of case reports and case series [1,2]. The advantage of allogeneic HSCT has been indicated in progressive dise...

12/09/2019
Research Article

A pilot study on treatment of infantile cystinosis with mesenchymal stem cells

Faysal Gok*, Cengiz Zeybek, Ayse Balat and Olcay Y Jones

Abstract

Infantile cystinosis is a lysosomal storage disease leading to end stage kidney disease at early ages. There is no effective treatment and patients require long term dialysis or kidney transplant for survival. We present our experience on three affected children who received ...

12/05/2019
Research Article

Aggressive hydration in early resuscitation phase does not provide mortality benefit in acute pancreatitis

Abu Omar Y*, Wang Y, Agrawal R, Randhawa T, Majeed M, Attar BM, Demetria MV and Simons-Linares CR

Abstract

Introduction: Fluid management is the cornerstone of treatment for acute pancreatitis (AP), but the proper rate and volume is still controversial. We aim to evaluate the role of aggressive hydration in AP patients.

Methods: We retro...

12/05/2019
Research Article

The motivational factors and adverse events experienced by healthy volunteers donating bone marrow for research

Mirella Ejiugwo, Georgina Shaw, Frank Barry, Janusz Krawczyk and Veronica McInerney*

Abstract

Background: With the advancement of cell therapy research, there is an increasing need for healthy volunteers (HV) to donate small volumes (30 ml) of human bone marrow (BM). The BM procedure required to procure small volumes is invasive, although short-lived ...

12/16/2019
Case Report

Aortic dissection causing 2 myocardial infarctions

Sebastian Szabo and Hans Martin Hoffmeister

Abstract

A 56-year-old man was admitted to our hospital because of sudden onset of right-sided thoracic pain. The ECG showed inferior ST segment elevations. He has been treated with aspirin, clopidogrel, unfractionated heparin and tenecteplase, and his symptoms resolved after 30 minut...

12/11/2019
Research Article

Co-extract mixture from Strophanthus hispidus (roots) and Aframomum meleguta (seeds) show phytochemical synergy in its anti-inflammatory activity

John Kenneth Mensah*, Amina Ibrahim and Yakubu Jibira

Abstract

Background: Combination of extracts from multiple plants are typically used in ethnomedicine to putatively offer more potent chemotherapeutic and chemopreventive effects than that of individual extracts from single plants. Aqueous extracts from two multipurpo...

12/10/2019
Research Article

To legalize cannabis in Ghana or not to legalize? Reviewing the pharmacological evidence

Kwesi Boadu Mensah* and Paa Kofi Tawiah Adu-Gyamfi

Summary

Background: Although illegal, Ghana has a long history of cannabis use. With changing perceptions, advocacy for legalization has increased globally. This study exams pharmacological evidence on the prospects and challenges of decriminalization and /or legaliza...

12/11/2019
Review Article

Risk factor of liver metastases in breast cancer

Akram Yazdani*

Abstract

Objective: The liver is the second most common site of distant metastases from breast cancer. We investigated the risk factor liver metastasis in patients with breast cancer.

Methods: We studied Age, Menopausal status, Histologic Ty...

12/10/2019
Review Article

Different optimization strategies for the optimal control of tumor growth

Sweilam NH, Tharwat AA and Abd El Moniem NK*

Abstract

In this article different numerical techniques for solving optimal control problems is introduced, the aim of this paper is to achieve the best accuracy for the Optimal Control Problem (OCP) which has the objective of minimizing the size of tumor cells by the end of the treat...

12/12/2019
Case Report

Embolic Septic Emboli with MRSA: A different source

Christian Castillo Latorre*, Mariela Rivera Agosto, Ilean Lamboy Hernandez, Mariana Mercader Perez, Dominic Sanchez Paredes, Marisol Santiago Irizarry, Jose Gutierrez Nuñez Onix, Cantres Fonseca, Alfonso Torres Palacios and William Rodriguez Cintron

Abstract

Septic Iliac vein thrombophlebitis with associated psoas abscess is a rare and severe entity, which diagnosis is challenging when no risk factor is clearly present. We are presenting a case of severe septic cavitary pulmonary emboli complicated with Acute Respiratory Distress...

12/09/2019
Case Report

Brainstem Death due to hypertension induced brain hemorrhage

Satyajit Patra* and Sreeraj Suresh

Introduction

Brain stem death is when a person has permanently lost the potential for consciousness and the capacity to breathe. When this happens, a machine called a ventilator keeps oxygen circulating through the person’s bloodstream - a person confirmed as being dead when the...

12/12/2019
Research Article

Postgraduate students’ perception of the educational environment of a wet lab training in Neurological Surgery Division, UCH, Ibadan

Malomo Adefolarin O*, Kafayat Bolaji Aminu, Adeolu Augustine A, Adeleye Amos O, Balogun James A, Badejo Oluwakemi A, Shokunbi Mathew T and Jegede Ayodele S

Summary

Objective: The importance of understanding the perceptions of medical students to their training environment cannot be overemphasized. The study evaluated the wet lab training organized for Senior Registrars in the Neurosurgery, Division of the University Coll...

12/05/2019
Research Article

Health care workers knowledge, attitude and practice towards hospital acquired infection prevention at Dessie referral hospital, Northeast Ethiopia

Hailemariam Gezie, Emebet Leta, Fikrte Admasu, Sisay Gedamu*, Abebe Dires and Debrnesh Goshiye

Abstract

Introduction: Contact of health care workers and patient at health facility lead to the transmission of pathogenic organisms to each other. Hospital acquired infection prevention is standardized guide lines contain multitude protocols needed to be implemented...

12/03/2019
Letter to the Editor

Effect evaluation of vitamin D level amongst patients with chronic hepatitis B

Freshteh Osmani*

Text

Vitamin D has immunomodulatory and antifibrotic properties, and therefore used for treatment of many of chronic liver disease [1]. Although there are many reports on the relationship between serum 25-hydroxyvitamin D3 levels and chronic liver diseases, but the relationship betwee...

12/16/2019
Case Report

Intracerebral Hemorrhage of Brainstem in triple pregnancy after in vitro fertilization by receiving Ovum Donation: A case report and review

Andreas Suhartoyo Winarno*, Lukas Schloesser, Frederic Dietzel, Percy Balan, Thomas Hoehn, Monika Hampl and Tanja Natascha Fehm

Abstract

Deliveries prior to 28 weeks’ gestation (extreme preterm birth) pose a global health concern, according to the World Health Organization (WHO). Extreme preterm birth is associated with several complications in the newborn and management in neonatal intensive care unit w...

12/11/2019
Research Article

The influence of opioid on the microstructural organization of the Wall OT the uterus of the white laboratory rat

Mateshuk-Vatseba LR, Ivankiv Ya T and Ivankiv TM*

Introduction

Drug addiction is one of the burning problems in the modern society. Annually there is a steady increase in the level of drug abuse. United Nations Office on Drugs and Crime publishes “World Drugs Report 2018”, where it was reported that about 275 million peop...

12/04/2019
Research Article

Bio-moleculear thermal oscillator and constant heat current source

R Panahinia* and S Behnia

Abstract

The demand for materials and devices that are capable of controlling heat flux has attracted many interests due to desire to attain new sources of energy and on-chip cooling. Excellent properties of DNA make it as an interesting nanomaterial in future technologies. In this pa...

12/09/2019
Review Article

Natural killer cells in patients with hematologic malignancies, solid tumors and in recipients of hematopoietic stem cell transplantation

Al-Anazi KA*, Al-Jasser AM and Al-Anazi WK

Abstract

Natural killer cells represent the first line of defense against infections and tumors and can be derived from various sources including: bone marrow, peripheral blood, specific types of human stem cells, and certain cell lines. The functions of natural killer cells are influ...

12/06/2019
Case Report

Scraping cytology and scanning electron microscopy in diagnosis and therapy of corneal ulcer by mycobacterium infection

Del Prete Salvatore, Marasco Daniela1, Del Prete Antonio, Meloni Marisa, Capaldi Roberto, Grumetto Lucia and Russo Giacomo*

Purpose: This work is aimed at demonstrating that scraping cytology and scanning electron microscopy can successfully assist in the diagnosis of nontuberculous mycobacteria infection. For this purpose, we report the use of both these techniques in the diagnosis of cornel ulcer in...

12/06/2019
Case Report

Meckel Gruber Syndrome: A rare and lethal anomaly

Zana Zegarac*, Zeljko Duic and Katarina Bojanic

Case Report

We wish to present our case of the rare Meckel-Gruber syndrome, diagnosed prenatally at 18 weeks’ gestation. Informed consent was obtained from both parents for publishing this case and including photos.

12/03/2019
Research Article

Previous antibiotic treatment as a risk factor for recurrent vulvovaginal candidiasis

Wen Yang#, You Nie#, Shujuan Wang, Hongwei Wang, Enfeng Zhao and Na Dou*

Abstract

The incidence of recurrent vulvovaginal candidiasis (RVVC) is extremely high. RVVC is likely to have a greater impact on patients. The aim of the study was to explore the risk factors of recurrent vulvovaginal candidiasis (RVVC) in the tropical coastal area. In this case-cont...

12/02/2019
Review Article

Microchimerism may be the cause of psychiatric disorders

Bulent Demirbek and Osman Demirhan*

Introduction

Microchimerism is a bidirectional exchange of fetal and maternal cells during pregnancy (Figure 1). Pregnancy is the most common and natural cause of chimerism, and bi-directional trafficking of hematopoietic cells occurs through the placenta. Therefore, we are all born a...