10/26/2018
Case Report

Preventing Peri-implantitis with a proper Cementation Protocol and with the consideration of alternatives to Cement-Retained Implant Restorations

Tony Daher*, Robert G Mokbel and Vahik P Meserkhani

Abstract

Successful implant restoration is depending on an adequate surgical and prosthetic protocol. In the last few years an increase in Peri-Implantitis has been attributed, in part, to the excess cement left around the implant collar and threads, leading in many cases to bone loss...

10/29/2018
Review Article

Endogenous sensitizer of beta-adrenergic receptors (ESBAR) and its analogs (review)

Victor Tsirkin*, Alexander Nozdrachev, Elena Sizova, Tatyana Polezhaeva, Svetlana Khlybova, Marina Morozova, Andrew Trukhin, Julia Korotaeva and Grigory Khodyrev

Abstract

The results of the 20 years studies of the presence in blood serum and other body fluids of endogenous modulators of adrenergic and M-cholinergic impact as a component of humoral link of autonomic nervous system. The article is devoted to the endogenous sensitizer of beta-adr...

10/23/2018
Research Article

Assessing the Neurocognitive function effects of ketamine in Cardiac Surgical patients

Demet Dogan Erol*

Abstract

Background: Despite remarkable progress in surgical,cardiopulmonary bypass (CPB) and anesthetic tecniques, neurocognitive damage still remains an important cause of postoperative morbidity in cardiac surgery. The aetiology of neurocognitive damage is likely t...

10/02/2018
Review Article

Urine Leak Following Kidney Transplantation: An Evidence-based Management Plan

Shafiq A Chughtai, Ajay Sharma and Ahmed Halawa*

Abstract

Care of kidney transplant recipient remains complex and long-term graft survival is not seen in every transplant recipient. Due to reduced supply and increased demand of human organs, more transplants are carried out using marginal grafts on emergency lists. Transplant recipi...

10/29/2018
Review Article

Current anesthesıa for Cesarean Sectıon

Demet Dogan Erol* and Ismail Aytac

Abstract

The choice of anesthesia for cesarean section should depend on the urgency of the procedure, in addition to the condition of the mother and fetus. It is widely accepted that regional anesthesia for cesarean section is preferable to general anesthesia. Regional techniques have...

10/31/2018
Research Article

Clinico-epidemiological characteristics and survival outcome of patients with hypertensive crisis at Kassala Hospital, Eastern Sudan

TajEldin M Abdallah*, Abdalazeem A Ibrahem, Ezeldein A Ali, Elbashir G Ahmed and AbdelAziem A Ali

Abstract

Introduction: Hypertensive crisis (HC) is recognized consequence of inadequate blood pressure (BP) control. A hypertensive crisis is further divided into hypertensive emergency (HT-E) and hypertensive urgency (HT-U).

Method: Using a...

10/27/2018
Short Communication

Ontario wait time strategy to solve long waiting problem

Satyajit Patra*

Short Communication

The Ontario government has been battling with the issue of extensive wait times in hospitals for several years. Although there are many complex reasons that stem off of the issues of wait times, such as available in patient beds and bed blockers (patients who stay ...

10/26/2018
Review Article

A Review on filaricidal activity of phytochemical extracts against filariasis and the Parasites Genomic Diversity

AM Gumel* and MM Dogara

Abstract

Filariasis is one of the Neglected Tropical Diseases (NTDs) known to be of serious public health importance and pose devastating socio-economic burden especially among the poor people in tropical and subtropical countries of the world. The parasite is responsible for lymphati...

10/30/2018
Review Article

Gravitation - Flat Power Field

Orlov SA

Abstract

A new principle of origin and the nature of the action of gravity forces are proposed. Forces of universal attraction have plane-symmetrical directions. On this basis, it becomes possible to reconsider certain regularities in natural science. The new principle of gravitation ...

10/30/2018
Review Article

Application of the Pyphagor’s Theorem for Correction of Ki and Ka constants of enzyme inhibition and activation

VI Krupyanko* and PV Krupyanko

Abstract

The analysis of dependence of the length projection of Li vectors of biparametrical inhibited and activated (La) enzymatic reactions from the length projection of vectors of monoparametrical inhibited and activated enzymatic reactions on the basic σ0 plane in three-dime...

10/29/2018
Research Article

Preclinical studies for a cationic liposome formulation containing Il-2 Intended for the treatment of Human Tumors

Maria Teresa Corona-Ortega*, Arturo Valle-Mendiola, Leonor Aguilar-Santelises, Araceli Garcia del Valle, Rosalva Rangel-Corona and Benny Weiss-Steider

Abstract

Human cervical cancer tumours expressing the IL-2 receptor (IL-2R) were induced in the peritoneal cavity of nude mice. The tumours were significantly reduced by the i.p. administration of either free IL-2 or liposomes containing this growth factor. No toxicity was observed in...

10/27/2018
Opinion

COPD and low plasma vitamin D levels: Correlation or causality?

Luca Gallelli*, Erika Cione, Stefania Zampogna and Gino Scalone

Opinion

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death and its prevalence and incidence is also related to smoking behavior [1]. COPD is still a chronic inflammatory and progressive disease caused by multifactorial agents including environmental pollu...

10/26/2018
Short Communication

Synthesis and Biological Evaluation of Fluorescein-Tagged 1-Methyl-o-carborane for Boron Neutron Capture Therapy

Lucas A Kuzmanic, Lauren E Zuidema, Jason A Misurelli, Kazuko Uno, Sherine F Elsawa*, Masao Takagaki* and Narayan S Hosmane*

Abstract

Fluorescein was conjugated with 1-methyl-o-carborane and the resulting bioconjugate was biologically evaluated through microscopic and flow cytometric studies in pancreatic cancer and squamous cell carcinoma cell lines. The uniform distribution of this bioconjugate, as well as ...

10/31/2018
Mini Review

Advances in research of the structural gene characteristics of the aflatoxin biosynthetic gene cluster

Qi-Zhang Li and Zhu-Mei He*

Abstract

Aflatoxins, produced by Aspergillus spp., are strongly toxic and carcinogenic fungal secondary metabolites. Aflatoxin biosynthesis is a complex process and involves at least 30 genes clustered within an approximately 75 kB gene cluster.In this paper, we reviewed curr...

10/24/2018
Research Article

Factors affecting physical activity of recuperating alcoholics in Asumbi- Homabay rehabiliation center, Kenya

Lucy Amanya Mutuli*, Peter Bukhala and Gordon Nguka

Abstract

Background: Alcoholism is a widespread problem in Kenya and is associated with severe impacts on health and quality of life of the individual. Physical activity is an affordable and sustainable adjunct treatment option for recuperating alcoholics; however its...

10/23/2018
Case Report

Septic arthritis of left shoulder in pregnancy following minor hand injury

Neelam Agrawal, Rhoughton Clemmey and Shamma Al-Inizi*

Septic arthritis of the shoulder joint is rare and might affect around 3% of the general population [1]. A delay in diagnosis may increase morbidity and lead to bone and cartilage destruction [2]. Septic arthritis is an unusual complication of pregnancy and can progress to permanent arthropathy a...

10/19/2018
Review Article

Does Veterinary Science have a future in Australia?

Maxwell JAL

Introduction

Although the veterinary art has been practiced since antiquity, the modern era began in the 18th century with the establishment of the discipline of “Veterinary Science” at universities. In the 19th century, veterinary education began in Australia with Kendall...

10/16/2018
Review Article

Finite-time thermodynamics: Realizability domains of thermodynamic systems and P. Salamon’s problem of efficiency corresponding to maximum power output of the system

Tsirlin AM, Sukin IA

Abstract

The paper analyses performance boundaries of systems converting the heat energy into the mechanical or separation work. Authors approach this problem from the view-point of the finite-time thermodynamics. Using thermodynamic balance equations, authors provide the algorithm fo...

10/17/2018
Case Report

Actinomycosis of the appendix

Lucas Wheatley*, Michael Lonne, James Bennnet and Bhavik Patel

Case Report

A 40 year old woman presented to the emergency department with acute on chronic abdominal pain in her right iliac fossa. On history her pain had been present for over 6 months and had previously been investigated with ultrasound, CT and a diagnostic laparoscopy several mon...

10/17/2018
Case Report

Intra-abdominal testicular tumour--A case report

Sardar Rezaul Islam*, Shafiqur Rahman, Shahalam Sarkar and Debabrata Paul

A 35-year-old man presented with swelling in the lower abdomen for 2 months. He was found to have left undescended testis. An ultrasound scan showed a solid floating pelvic mass. His chest x-ray and tumour markers for testicular cancer were normal. Exploratory laparotomy revealed the left intr...

10/17/2018
Research Article

Trypanosoma dionisii as an experimental model to study anti-Trypanosoma cruzi drugs: A comparative analysis with benznidazole, posaconazole and amiodarone

Barrias ES, Borges TR and De Souza W*

Abstract

Chagas disease is a public health problem in Latin America and its treatment is based on the use of benznidazole or nifurtimox compounds. Both present problems such as resistance, inefficiency in chronic infection and cytotoxic effects. New compounds such as posaconazole and ...

10/17/2018
Case Report

Challenges in the diagnosis and management of severe Pneumocystis jirovecii pneumonia in a non-HIVinfected patient - A case report

Mark Taubert, Lorenz Weidhase, Sirak Petros and Henrik Rueffert*

Abstract

A 64-year-old woman was referred to our hospital due to progressive dypnoea for the past week, combined with fever and type 1 respiratory failure. White blood cell count and procalcitonin level were normal. The Chest X-ray showed bilateral disseminated pulmonary infiltrates. ...

10/15/2018
Case Report

Novel Complication of Nusinersen Treatment: Hyponatremia

Yasemin Coban*

Abstract

There are variations in therapeutic regimens of different liver diseases. The accurate diagnosis ensNusinersen treatment is a novel therapy for spinal muscular atrophy (SMA) type 1; consequently, the adverse reactions of the therapy, have not been well known, yet. The present...

10/15/2018
Opinion

Effectiveness of the lifestyle modifications in prevention and control of sexually transmitted diseases (STDs): Focus on Islamic lifestyle

Mohammad Rabbani Khorasgani*

Text

The advancement of human researches and scientific activities in the field of diseases prevention and treatment, has not diminished the importance of sexually transmitted diseases (STDs). Despite the continuous efforts for prevention and control of them, many peoples suffers from...

10/12/2018
Case Report

Novel Non-invasive Management of Chronic Groin Pain from Fibrosed Contracted Inguinal Ligament

A Lokeshwar Raaju and N Ragunanthan*

Abstract

A 34-year-old male patient presented with the complaint of chronic pain in the left groin following left side testicular vein ligation for varicocele. Ilio-inguinal neurectomy and cremaster muscle division was done in another hospital for the pain but with no relief of pain. ...

10/11/2018
Case Report

Endocrine abnormalities in two siblings with Rothmund Thomson Syndrome

Nagehan Aslan* and Ozgur Pirgon

Abstract

Rothmund-Thomson syndrome is a rare autosomal recessive disorder characterized by poikiloderma (skin atrophy, telangiectasia, hyper- and hypopigmentation), congenital skeletal abnormalities, short stature, premature aging, and increased risk of malignant disease. Two siblings...

10/10/2018
Research Article

Effects of Balanites Aegyptiaca (del) Seed Cake on Growth and Carcass Performance of Growing Rabbit

Ogori AF, Makinde JO, Ogori J

Abstract

A study on growth and carcass performance was conducted to evaluate the effect of Balanites aegyptiaca seed cake meal (BASCM) as a substitute for groundnut cake in the diet of growing rabbit. Five experimental diets were formulated representing the following treatments: T1, T...

10/12/2018
Research Article

Percentage of Positive Biopsy Cores Predicts Presence of a Dominant Lesion on MRI in Patients with Intermediate Risk Prostate Cancer

Jason M Slater, William W Millard, Samuel M Randolph, Thomas J Kelly and David A Bush*

Abstract

Background: Biopsy findings of percentage of positive biopsy cores, percentage of cancer volume, and maximum involvement of biopsy cores have been shown to have prognostic value and correlate with magnetic resonance imaging (MRI) findings of extracapsular ext...

10/23/2018
Editorial

Knowledge or Money: Which One is More Important?

Narayan S Hosmane*

Editorial

When I asked the students in my general Chemistry class whether grade is more important than knowledge, a majority of them opted for grades over knowledge and this answer did not surprise me a bit as the smart phones are available for them to think while their brains are cor...

10/23/2018
Research Article

Final solution in femoroacetabular impingement - Threaded cups in hip revision surgery 2002-2012

Stepan Magersky*

Abstract

Purpose: Here, we report the complications of endoprosthesis with threaded cups according to our application in cases of complicated acetabulum (hip revisions and femoroacetabular impingement (FAI)).

Methods: A total of 504 patients...

10/17/2018
Research Article

An observational study of the occurrence of anxiety, depression and self-reported quality of life 2 years after myocardial infarction

Catrin Henriksson, Mona-Lisa Wernroth and Christina Christersson

Abstract

Background: Patients with myocardial infarction (MI) often experience anxiety, depression and poor quality of life (QoL) compared with a normative population. Mood disturbances and QoL have been extensively investigated, but only a few studies have examined t...

10/19/2018
Research Article

Analysis of static, dynamic, and pelvic stability in junior badminton players of South Asia

Manan Vora*, Digpal Ranawat, Apoorva Tiwari and Manit Arora

Summary

Badminton is a sport that requires a player to perform while being still, as well as in motion. Stability is the ability to maintain or control joint movement or joint position, in the static as well as dynamic state. Improvement in stability could help maintain body cont...

10/11/2018
Research Article

What is the Cost of Measuring a Blood Pressure?

Steven A Yarows*

Abstract

Rationale: Blood Pressure measurement has transitioned to the oscillometric method in most hospitals in the United States, however out-patient offices mainly use the auscultatory technique.

Objective: To determine time taken to meas...

10/11/2018
Opinion

Use of Rivaroxaban and Apixaban, Two Non-Vitamin K Antagonist Oral Anticoagulants (NOACs), in Renally Impaired Patients - the limits of our knowledge

Kenneth T Moore* and Maria Langas

Opinion

Patients with chronic kidney disease are at increased risk of thromboembolic complications and are therefore often managed with anticoagulation therapy [1]. While these patients are traditionally treated with Vitamin K antagonists (VKAs), the Non-Vitamin K antagonist oral anti...

10/13/2018
Clinical Image

A rare case of Diabetic Foot in male of middle age has been shown Diabetic foot

Sujit K Bhattacharya*

A rare case of Diabetic Foot in male of middle age has been shown.

Diabetes mellitus is a chronic disease due to complete absence of its hormone, Insulin, or has the hormone which is ineffective. This disease affects individuals of all ages and both sexes. When the disease affects i...

10/15/2018
Editorial

Endogenous Ligands of Toll Like Receptors: A Danger Signal to the Brain Memory at High Altitude

KP Mishra* and Shashi Bala Singh

Editorial

Sojourn to high altitude may affect various human systems if proper acclimatization not followed. If acclimatization failed, sojourners may suffer with high altitude sickness such as acute mountain sickness (AMS), high altitude pulmonary edema (HAPE) and high altitude cerebr...

10/05/2018
Research Article

Amyotropyc Lateral Sclerosis and Endogenous -Esogenous Toxicological Movens: New model to verify other Pharmacological Strategies

Mauro Luisetto*, Behzad Nili-Ahmadabadi, Nilesh M Meghani, Ghulam Rasool Mashori, Ram Kumar Sahu, Kausar Rehman Khan, Ahmed Yesvi Rafa, Luca Cabianca, Gamal Abdul Hamid and Farhan Ahmad Khan

Abstract

In 1874 J.M. Charcot was the first to describe ALS amyotrophic lateral sclerosis, a disease with an high non response therapy rate also to the actual therapy.

ALS is not clearly associate to only single etio-patogenetic movens but many process seem involved.

...

10/05/2018
Review Article

Vigour of CRISPR/Cas9 Gene Editing in Alzheimer’s Disease

Jes Paul*

Abstract

Ailment repairing regiments has turn out to be arduous, despite a plenty of understanding and knowledge acquired in the past relating to the molecular underpinnings of Alzheimer’s disease (AD. Umpteen clinical experiments targeting the fabrication and accumulation have ...

10/04/2018
Review Article

Validation of HPLC-UV method for determination of amoxicillin Trihydrate in capsule

Sendanyoye Marcel*, Uwambajineza Tito, Ineza Ines and Nahimana Jean Pierre

Abstract

The intention of the present work is to validate an easy, better and reasonable approach for estimation of amoxicillin trihydrate in tablet formulation by opposite segment(reverse phase) HPLC –UV with advanced conditions and parameters for habitual use in Rwanda well kn...

10/02/2018
Research Article

Bacillus amyloliquefaciens as a plant growth promoting bacteria with the interaction with of grass salt Distichlis palmeri (Vasey) under field conditions, in desert of Sonora, Mexico

Ruiz Alvarado Cristina, Jesus Borboa Flores, Victor Cardenas Salazar, Soto Ortiz Roberto, Lourdes Díaz Cervantes and Rueda Puente Edgar O*

Abstract

The halophyte Distichlis palmeri (Vasey) is a plant resource with high potential to be harvested in the coastal areas of northwestern Mexico; enlarge the knowledge and domestication for its incursion into the agricultural sector, plays an important role for arid areas with sa...