09/20/2017
Research Article

Rehabilitation of proximal humerus fractures: An environmental scan of Canadian physiotherapy practice patterns

Lowell L Kwan and Norma J MacIntyre*

Abstract

Background: Proximal humerus fractures (PHFs) are common injuries particularly in older adults. Evidencebased protocols for PHF rehabilitation are lacking and physiotherapists use a variety of interventions.

Purpose: To determine pr...

09/25/2017
Short Communication

Kummoona Chondro-Ossous Graft for Reconstruction of the Temporomandibular Joint in Children

Raja Kummoona*

Short Communication

There are a lot of controversy about the usage of graft for reconstruction of the TMJ, many researchers tried in the past different technique to be applied in the TMJ [1], for restoration of growth and all failed and some of these techniques may be used for one tri...

09/27/2017
Case Report

Gastric Mucosal Calcinosis

Vedat Goral*, Irem Ozover and Ilknur Turkmen

Abstract

Gastric mucosal calcinosis is a very rare pathology of the gastric mucosa. It may develop secondary to several diseases but may also be idiopathic in some cases. In this case, gastric mucosal calcinosis was diagnosed with endoscopic biopsy performed for a patient who presente...

09/27/2017
Review Article

Ra-223 dichloride management in a Nuclear Medicine Unit: experience of a referral institution

Giulia Anna Follacchio*, Viviana Frantellizzi, Francesco Monteleone, Giuseppe De Vincentis and Mauro Liberatore

Abstract

Ra-223 dichloride is a first-in-class alpha-emitting radiopharmaceutical recently introduced into clinical practice for treatment of men with Castration-Resistant Prostate Cancer (CRPC) and symptomatic bone metastases.Due to the proven benefit on Overall Survival and the favo...

09/28/2017
Mini Review

A decade of targeted therapy for non-small cell lung cancer

Khalid Abu Ajaj*

Abstract

Chemotherapy is one of the main treatment options for cancer. However, chemotherapeutic agents usually suffer from poor pharmaceutical properties that restrict their use. Targeted therapy drugs have been developed to specifically target changes in cancer cells that help ...

09/27/2017
Research Article

Fluticasone furoate/Vilanterol 92/22 μg once-a-day vs Beclomethasone dipropionate/Formoterol 100/6 μg b.i.d. in asthma patients: a 12-week pilot study

Claudio Terzano* and Francesca Oriolo

Abstract

Two of the most recent LABA/ICS combinations for treatment of persistent asthma are Fluticasone furoate/Vilanterol 92/22 μg (Ellipta) and Beclomethasone dipropionate/Formoterol 100/6 μg (Nexthaler).

Objective: To compare once-daily Fluticasone...

09/27/2017
Mini Review

Joint Functional Screening for Older Adults: Clinical Prevention of Accidental Fall

Balwant S Bains*

Abstract

As people get older, chronic diseases become an important reason of disability while a decline in physical functions is related to aging among the elders, which may lead to dependency and isolation of the older adults. Body asymmetry and imbalance body alignment can bring add...

09/27/2017
Research Article

Evaluation of genetic diversity in germplasm of paprika (Capsicum spp.) using random amplifi ed polymorphic DNA (RAPD) markers

Renganathan P, Ruiz-Alvarado C, Hernandez-Montiel LG, Prasath Duraisamy and Rueda-Puente EO*

Abstract

Capsicum spp. is one of the most important economical horticulture crops due to its high consumption either by fresh vegetable or dried spice. Molecular genetic markers offer a number of applications in the genetic improvement of crop plants, which plays an important...

09/26/2017
Case Report

CT signs of pressure induced expansion of paranasal sinus structures

Peter AR Clement* and Stijn Halewyck

Summary

Several articles have been written about hyper inflated sinus structures. Never before, however, a complete overview of all possible pressure induced variations of sinus anatomy have been published. The aim of this study was to make an inventory of the most common CT signs of ...

09/22/2017
Research Article

Unrecognized myocardial infarction in the elderly

Haakon H Eilertsen, Peer K Lilleng, Bjorn Maehle and Inge Morild*

Abstract

This study presents the frequency of old myocardial infarctions (OMI), and the frequency of unrecognized myocardial infarction (UMI) in elderly people in a forensic material. It was also examined if predisposing factors of UMI could be identified. Of special interest was also...

09/26/2017
Thesis

Retrosynthesis analysis; a way to design a retrosynthesis map for Pyridine and pyrimidine ring

Samar S Fatahala*

Abstract

Pyridine and pyrimidines are amongst the most important, well known heteroaromatic rings, owning to their bioactive importance. Herein, an idea about how to design the synthetic pathway for these rings using retrosynthesis analysis techniques.

09/26/2017
Research Article

Synthesis of some new Schiff bases of Pharmaceutical Interest

Ajay Kumar, Shweta Verma, Arun K Mishra and Sushil Kumar*

Abstract

A series of Schiff bases of diphenylamine derivatives have been synthesized and evaluated in vitro for their antibacterial activity against pathogenic both Gram-positive bacteria B. subtilis and Gram-negative bacteria E. coli using ciprofloxacin as standard drug at conc. of 5...

09/25/2017
Research Article

The master regulator gene PRDM2 controls C2C12 myoblasts proliferation and Differentiation switch and PRDM4 and PRDM10 expression

Di Zazzo Erika, Bartollino Silvia* and Moncharmont Bruno

Abstract

The Positive Regulatory Domain (PRDM) protein family gene is involved in a spectrum variety of biological processes, including proliferation, differentiation and apoptosis: its member seem to be transcriptional regulators highly cell type and tissue peculiar, towards histones...

09/20/2017
Case Report

Evolution of anaesthesia in transapical aortic valve implantation Running head: Anaesthesia and transcatheter valve

Marzia Cottini*, Lappa A, Donfrancesco S and Francesco Musumeci

Abstract

The Transcatheter Aortic Valve Implantation (TAVI) had emerged more and more in the last twenty years. According to the scientific literature, this is an approved, suitable and alternative therapeutic choice to conventional surgery for aortic valve disease in high risk patien...

09/25/2017
Research Article

Effects of Site Factors on the Clonal Growth of Phyllostachys bambusoides f. shouzhu Yi

Lijuan Chen, Xia Zhang, Cuibin Tang and Xiaohong Gan*

Abstract

In order to provide theoretical foundation for forestation of Phyllostachys bambusoides f. shouzhu Yi, the site factors, and the morphological character and biomass of standard bamboo were investigated in 16 sample spots of bamboo forest in Liangping county,...

09/25/2017
Review Article

Spiritual and religious Islamic perspectives of healing of posttraumatic stress disorder

Mevludin Hasanovic*, Izet Pajevic and Osman Sinanovic

Abstract

It is known today that psycho-trauma and PTSD cause different levels of mental and social dysfunction. Human spirituality and capacity to meet further life difficulties become severely damaged. There is wide accepted attitude today that in holistic approach in process of heal...

09/20/2017
Research Article

Intravitreal Ranibizumab/ Lucentis (IVTL) injections in Glaucoma patients-Intraocular Pressure (IOP) elevation and the use of Anterior Chamber Paracentesis (ACP)

EA Ansari* and H Huraira

Abstract

Purpose

• To assess the short term effects of intravitreal Lucentis (IVTL) on intraocular pressure in patients with ocular hypertension and glaucoma.

• To determine rate of anterior chamber paracentesis (ACP) requi...

09/20/2017
Research Article

Non-hemodynamic factors associated to the risk of developing hypertensive cardiopathy

Alexis Alvarez-Aliaga*, Julio Cesar Gonzalez-Aguilera, Liliana del Rosario Maceo-Gomez, Lic David del Llano Sosa, Raul Leyva-Castro and Rosa Ojeda-Vazquez

Abstract

Introduction: Hypertensive cardiopathy is the target organ lesion caused by arterial hypertension (HTN) that exhibits the highest morbidity and mortality rates. Although the importance of hemodynamic overload exerted by HTN on the onset of cardiopathy is well...

09/20/2017
Case Report

Kikuchi’s disease in a young Scandinavian woman

Sannia Mia Sveningsen Sjostedt*, Eva Hebbelstrup Rye Rasmussen, Anette Bygum and Line Kanstrup Springborg

Abstract

A 21 year-old woman presented with cervical lymphadenopathy and night sweats. Initially, lymphoma was suspected and one of the enlarged lymph nodes was excised in order to make a diagnosis. Histopathological examination revealed Kikuchi’s disease, which is usually a ben...

09/20/2017
Thesis

Impedance audiometry: Stapedial reflex eliciting conditions

Mojmir Lejska*

Summary

The work is an attempt to create a complete system of conditions which influence genesis, existence, and response characteristics of stapedial reflex in impedance audiometry. The author divides the conditions into the internal-reflex arc integrity, temporal acoustic summation,...

09/20/2017
Mini Review

The use of Allergoids and Adjuvants in Allergen Immunotherapy

Celso Eduardo Olivier*

Abstract

Allergen immunotherapy (AIT) is the unique curative treatment to help allergic patients to get over their allergies. With a personalized approach, AIT is the best example of precision medicine. After a century of intensive studies and innovative discoveries, allergists...

09/22/2017
Clinical Image

Andy Gump deformity

Pirabu Sakthivel*, Chirom Amit Singh, and Suresh Chandra Sharma

Clinical Image

A 63 year old gentleman presented with ulcer over the lower alveolus for the past 4 months duration. The patient also had pain, loose lower central incisors and occasional bleeding from the ulcer while brushing. On examination an ulceroproliferative growth was seen invo...

09/22/2017
Research Article

How Bruguiera gymnorhizza seedlings respond to climate change induced salinity rise?

Prosenjit Pramanick, Subrata Trivedi, Sufia Zaman and Abhijit Mitra*

Abstract

A study was undertaken during August 2017 to evaluate the effect of salinity on chlorophyll a, chlorophyll b, total chlorophyll, and carotenoid and proline contents of hydroponically grown seedlings of Bruguiera gymnorhizza. The primary aim was to observe its tolerance to cha...

09/15/2017
Case Report

A new heart: portraying the physiologic anatomo-functional reconstruction in ischemic cardiomyopathy

Marco Cirillo*, Marco Campana, Anna Bressanelli and Giovanni Troise

Summary

Fiber-based model of the left ventricle is known since 1628 but the complex 3D structure of myocardial fibers has not taken into account in normalcy or in disease until the last decade. We here present the case of a 60-year-old female patient affected by ischemic cardiomyopath...

09/21/2017
Case Report

Nicotinamide as a treatment option of Age-Related Macular Degeneration

Yuchen Lin, Peter F. Zipfel and Christine Skerka*

Case Report

Age related macular degeneration is a severe disease of mainly elderly people and leads to central vision loss because of the degeneration of the retinal pigment epithelium [1]. Genetic and environmental factors are responsible for the accumulation of extracellular materia...

09/07/2017
Research Article

Arid3a regulates mesoderm differentiation in mouse embryonic stem cells

Melissa Popowski, Bum-kyu Lee, Cathy Rhee, Vishwanath R Iyer and Haley O Tucker*

Abstract

Research into regulation of the differentiation of stem cells is critical to understanding early developmental decisions and later development growth. The transcription factor ARID3A previously was shown to be critical for trophectoderm and hematopoetic development.Expression...

09/18/2017
Case Report

Preservation of Haemostasis with Anti-thrombotic Serotonin Antagonism

Mark IM Noble* and Angela J Drake-Holland

Abstract

An enquiry into the lack of attention awarded to serotonin antagonism in the treatment of arterial thrombosis revealed that the mode of action of serotonin and its platelet receptor antagonists was an action upon thrombus growth, and not, as with other anti-platelet drugs upo...

09/12/2017
Case Report

Cytomegalovirus pneumonia and Cryptogenic organizing pneumonia following pediatric stem cell transplantation for leukemia

Zuhre Kaya*, Tuba Sismanlar, Ayse Tana Aslan, Oznur Konus Boyunaga, Isıl Fidan Balcı, İdil Yenicesu and Ulker Kocak

Abstract

Background: Knowledge of pulmonary complications (PCs) in children after hematopoetic stem cell transplantation (allo-HSCT) is limited; most data are from adult studies.

Case: We describe a 8 year old girl with high risk acute myelo...

09/08/2017
Case Report

Sinking Skin Flap Syndrome

Liew BS*, Rosman AK and Adnan JS

Case Summary

A previously healthy 26-year-old gentleman, referred from a state hospital with history of alleged fall from 10 feet height at a construction site on the same day. Glasgow coma scale (GCS) at that hospital was E2 V2 M5. He was brought in to our Emergency Unit, Hospital Ku...

09/07/2017
Case Report

Unusual presentation of a bilateral basilar stroke: Bradycardia

Zidouh S*, Jidane S, Nabhani T, Chouaib N, Sirbou R, Belkouch A and Belyamani L

Abstract

We report a case of 79-year-old man who presented to our emergency department (ED) for lipothymia. The patient developed significant bradycardia with hypotension. His EKG objectified a slow atrial fibrillation .the patient rapidly installed a coma. A non-contrast CT brain sca...

09/15/2017
Case Report

Dieulafoy’s Lesion related massive Intraoperative Gastrointestinal Bleeding during single Anastomosis Gastric Bypass necessitating total Gastrectomy: A Case Report

Ashraf Imam, Khalayleh Harbi*, Miller Rafael, Khoury Deeb, Buyeviz Victor, Guy Pines and Sapojnikov Shimon

Abstract

Introduction: Immediate postoperative gastrointestinal bleeding following bariatric bypass surgery is a major complication, and usually results from staple line hemorrhage or conventional gastro-esophageal causes. Dieulafoy`s lesion is a rare cause of gastroi...

09/11/2017
Letter to the Editor

Exploring the Debate on Vaccines

D. John Doyle*

Letter to Editor

A thought-provoking debate in the popular literature concerning vaccination has blossomed in recent years [1-6]. While “traditionalists” support universal immunization against a variety of infectious diseases, many influential individuals hold that vaccina...

09/14/2017
Review Article

Anxiety and depression as an effect of birth order or being an only child: Results of an internet survey in Poland and Germany

Jochen Hardt*, Lisa Weyer, Malgorzata Dragan and Wilfried Laubach

Abstract

Background: Various studies examined the effect of birth order. First born children show usually better cognitive performance than their later born siblings. Studies on emotional aspects yield heterogeneous results, sometimes in favour of first born, sometime...

09/19/2017
Case Report

Frequency specific microcurrent resolves chronic pain and adhesions after ulnar transposition surgery

Jodie Adams* and Carolyn McMakin

Summary

Frequency specific microcurrent (FSM) has been used to treat myofascial pain syndrome [1,2] fibromyalgia associated with spine trauma [3], delayed onset muscle soreness [4], acute and chronic neuropathic pain [5] and chronic scarring in burn patients [6].In this case, its use ...

09/08/2017
Case Report

The efficacy of complex Decongestive Physiotherapy in patients with Bilateral Primary Lower Extremity Lymphedema and Untreatable multiple health conditions: A Case Report

Humeyra Kiloatar PT*

Abstract

Background: Primary lymphedema occurs as a result of genetic abnormalities of the lymph system. Currently, complex decongestive therapy is accepted as the standard treatment of the lymphedema. In this case presentation, we described the management of bilatera...

09/18/2017
Mini Review

Mechanism-related Teratogenic, Hormone Modulant and other Toxicological effects of Veterinary and agricultural surfactants

Andras Szekacs*

Summary

Veterinary and agricultural surfactants are supposed to be inert additives, yet these substances commonly exert biological side-effects, in given cases synergistic with those of the active ingredients of these preparations. This is explicitly seen in altered toxicity of veteri...

09/06/2017
Research Article

Investigation on Theileria lestoquardi infection among sheep and goats in Nyala, South Darfur State, Sudan

Osman TM, Ali AM*, Hussein MO, El Ghali A and Salih DA

Abstract

This study was conducted in Nyala, South Darfur State, Sudan during August-September 2015 to study the seroprevalence of ovine and caprine theileriosis and to identify the tick infesting sheep and goats. For this purpose, total of 150 samples (ticks, blood smear and sera) wer...

09/18/2017
Case Report

Osteogenic Accelerated OrthodonticsTM for treatment of a Skeletal Class II patient with moderate crowding

Armando Montesinos F and Marisol Perez Gasque B

Abstract

Introduction: A 17 years old male patient was treated at the University orthodontic department. He had the chief complaint of unaesthetic  appearance of his teeth, mostly for anterior crowding. The pretreatment records showed a Class II skeletal relation...

09/05/2017
Research Article

Anemia response to Methoxy Polyethylene Glycol-Epoetin Beta (Mircera) versus Epoetin Alfa (Eprex) in patients with chronic Kidney disease on Hemodialysis

Alaa K Dhayef*, Jawad K Manuti and Abdulwahab S Abutabiekh

Abstract

Objective: Anemia, a common complication of chronic kidney disease, usually develops because of erythropoietin deficiency. Maintaining target hemoglobin (Hb) with minimal variability is a challenge in hemodialysis (HD) patients. The aim of this study is to co...

09/05/2017
Research Article

Organic compositional analysis of propellant powders using monolithic material sorption extraction (MSSE)-a feasibility study

Ellen Goudsmits, George P Sharples and Jason W Birkett*

Abstract

The application of monolithic material sorption extraction, specifically MonoTrapTM, to the extraction of organic gunshot residue (OGSR) compounds from unburnt propellant powders is described. Four different MonoTraps were assessed for their capability to extract OGSR compoun...