12/29/2017
Short Communication

The effects of alcohol taxation and pricing policies on vodka sales in Russia

Razvodovsky YE

Background: The majority of aggregate econometric studies indicate that higher taxes and real prices on alcohol significantly reduce the alcohol consumption.

Objectives: To estimate the effects of recent alcohol taxation and pricing policies on vodk...

12/29/2017
Review Article

Nano-formulations for Ophthalmic Treatments

Mahima John and Rajesh N Gacche*

Ocular disorders encompass a multitude of diseases that are unique in their cause, therapy and degree of severity. Due to distinctive morphology of the eye, efficient ocular drug delivery has proven to be a difficult task. Current treatments of ophthalmological diseases include the usage of bo...

12/28/2017
Case Report

Brachial Plexus Schwannoma: Report of 4 cases with Intralesional Enucleation

Jennette SY Chan* and Josephine WY Ip

Brachial plexus tumours are rare. It comprises of only 5% of all tumours of upper limb [1]. The two most common brachial plexus region tumors are schwannomas and neurofibromas [2 4].Both are benign and arise from the nerve sheath. XiaotianJia et al., published a large case series of 143 patien...

12/29/2017
Editorial

Stemness of Mesenchymal Stem Cells

Tong Ming Liu*

Mesenchymal stem cells (MSCs) are multipotent adult stem cells that can
self-renew and differentiate into a variety of cell types including chondrocytes, osteocytes and adipocytes.MSCs reside in bone marrow, adipose tissues, cord blood, peripheral blood, placenta, Wharton’s jelly, fe...

12/29/2017
Research Article

Association between bh4/bh2 ratio and Albuminuria in Hypertensive Type -2 Diabetic patients

Jose Aviles-Herrera, Karla C Arana-Pazos, Leonardo Del Valle-Mondragon, Carolina Guerrero-García and Alberto Francisco Rubio-Guerra*

Endothelial dysfunction and inflammation play a key role in the pathophysiology of diabetic nephropathy; Tetrahydrobiopterin (BH4) is an essential cofactor for nitric oxide synthase, when BH4 is reduced to dihydrobiopterin (BH2), endothelial dysfunction is induced.

Pur...

12/29/2017
Research Article

Role of Accessory Right Inferior Hepatic Veins in evaluation of Liver Transplantation

Awais Ahmed, Abdu Hafeez Baig*, Mirza Akmal Sharif, Umair Ahmed and Raj Gururajan

Purpose: The purpose of the study is to access the prevalence of accessory right inferior hepatic veins and their relevant significance in liver transplantation.

Materials and Methods: A retrospective study was done in which the CT of 82 potential l...

12/29/2017
Research Article

Prospective Clinical Study to Find out Epidemiology of Xerophthalmia in Children in a Tertiary Care Centre in India

Deepak Mishra*, Megha Gulati, Prashant Bhushan, Nilesh Mohan and Bibhuti Sinha P

Objective: To study the epidemiology of xerophthalmia in children 2-6 years of age in North India.

Methods: A prospective clinical study was done at two tertiary care centers of North India between 2010 to 2016, Cases were selected from routine OPD ...

12/27/2017
Short Communication

Maternal thyroid dysfunction and neonatal cardiac disorders

Ahmed RG*

The normal levels of thyroid hormones (THs; thyroxine, T4 & 3,5,3′-triiodo-Lthyronine, T3) are necessary for the normal development [1-48], particularly the fetal and neonatal cardiac growth and development [49].The actions of THs are facilitated genomically by thyroid receptors (TRs, α and...

12/27/2017
Mini Review

Neuro-ophthalmological emergency disorders: A general view

Burak Turgut*, Feyza Calis Karanfil and Fatos Altun Turgut

Neuro-ophthalmological emergency disorders usually occur with symptoms of visual loss, diplopia, ocular motility impairment and anisocoria. In this mini-review, we aim to take look the common neuro-ophthalmological emergency disorders. The delayed diagnosis of the neuro-ophthalmological emerge...

12/26/2017
Research Article

Synthesis, Radioiodination and Biological distribution of 5-(5-(tributylstannyl) benzofuran-2-yl) pyridin-2-amine as an amyloid imaging agent

Atteyat A Labib* and Mohsen B Challan

In this work an efficient method developed for the synthesis of 125I-benzofuran-2-yl) pyridin-2-amine (125IBPA), followed by radioiodination with 125I by using Chloramine-T at pH 8. The reaction proceeds within 10 min at room temperature (20-25°C). The radiochemical yield determined by Thin-L...

12/26/2017
Short Communication

Brain response in some systemic immune condition-Toxicological aspects

Luisetto M*

From biomedical literature “autism disorder are involved in young patient, that we have abnormalities (Imaging, histology) in some brain areas, and a comples symptomatology. Genetic and environment can produce some unbalances in brain grow and immunitary situation is involved. Apoptotic sign...

12/27/2017
Case Report

Failure to Autopsy: The Otto Warmbier Case

Steven A Koehler* and Victor W Weedn

Coroner and medical examiner offices are charged with the medicolegal investigation of deaths to determine the cause and manner of death. We describe the recent high-profile case of Otto Warmbier, who tragically died shortly after his return in a coma from North Korea and in which the coroner ...

12/18/2017
Case Report

Hepato-Pulmonary syndrome and Porto-Pulmonary Hypertension: Rare combination cause of Hypoxemia in patient with end-stage renal failure on Hemodialysis and hepatitis C Induced Decompensated Cirrhosis

Awad Magbri*, Mariam El-Magbri and Eussera El-Magbri

The case is that of 83 year-old African American man with hypertension, hepatitis C induced decompensated cirrhosis with ascites, end-stage renal disease (ESRD) on hemodialysis, fluid overload with peripheral edema and chronic hypotension. The patient was referred to the dialysis access cente...

12/20/2017
Case Report

Catamenial pneumothorax: Presentation of an uncommon Pathology

Rui Haddad*, Caterin Arevalo and David Nigri

The catamenial pneumothorax is defined as the accumulation of air in the pleural cavity that appears in women infrequently and spontaneously with various clinical presentations. Actually, it is considered as an extremely rare entity with few cases described in the literature, that is the reaso...

12/14/2017
Case Report

Giant Lipoma Anterior Neck: A case report

Gowri Sankar M, Manu CB* and Arun Alexander

Abstract

Lipoma is a benign mesenchymal tumor with a thirteen percent incidence in head and neck region. Posterior triangle is the most common location while anterior neck lipoma is a rare one. Giant lipomas >10cm have been reported in different parts of the body but rarely in the ...

12/22/2017
Review Article

The Role of Omega-3 Essential Fatty Acids in Dry Eye Disease

William J Faulkner*

One of every four visits to eye care professionals is for dry eye disease which affects an estimated 7-34% of Americans [1].Knowledge regarding etiology and treatments has advanced exponentially in the last 20 years. As recently as 1997, in the mega textbook Cornea, it was stated “The mechan...

12/21/2017
Thesis

Short term effect of Intravenous Intermittent Iron Infusion versus Bolus Iron Infusion on Iron parameters in Hemodialysis patients

Iman Ibrahim Sarhan, Hussein Sayed Hussein, Islam Omar Elshazly* and Mahmoud Salah Hassan

Intravenous iron is used in combination with erythropoi esis-stimulating agents to treat the anemia of hemodialysis patients, however, there is variety in the dose and the frequency. So we compare bolus intravenous iron administration protocol vs an intermittent intravenous iron infusion proto...

12/08/2017
Case Report

It is not invisible! A case report of 2 patients with scalp Lichen Planopilaris mimicking Androgenic Alopecia

Sorbellini Elisabetta, Pinto Daniela, Marzani Barbara and Fabio Rinaldi*

Lichen Planopilaris is known as the form of Lichen Planus typical of the scalp. It is classified as a lymphatic disease and is characterized by chronic inflammation which leads to cicatricial alopecia. Its causes are not yet well characterized but its etiology seems to strongly correlates with...

12/08/2017
Research Article

Lifestyle Diseases and the Hair Growth Cycle: A multidisciplinary approach using Nourkrin® with Marilex®, a proteoglycan replacement therapy, for anagen induction and maintenance

Thom E* and Thom EW

Multiple studies have investigated the relationship between androgenetic alopecia and cardiovascular disease, including studies that have identified elevated rates of cardiovascular disease in patients with vertex hair loss, vertex and frontal hair loss, early onset hair loss and rapidly progr...

12/07/2017
Research Article

Intraepidermal Injections of Autologous Epidermal Cell Suspension: A new promising approach to Dermatological Disorders. Preliminary Study

Elisa Borsani, Luigi Fabrizio Rodella, Elisabetta Sorbellini, Rita Rezzani, Daniela Pinto, Barbara Marzani, Giovanna Tabellini, Mariangela Rucco and Fabio Rinaldi*

Regenerative medicine is a modern approach of dermatological treatment, using Epidermal Cells of the interfollicular epidermis (ESCs) for their effect in skin regeneration in chronic ulcers and burns, melanoma, vitiligo, junctional epidermolysis bullosa.Intraepidermal injections of autologous ...

12/07/2017
Review Article

Role of polyamine metabolism in plant pathogen interactions

Magda Pal* and Tibor Janda

Polyamines are aliphatic amines found in all living cells, and they are necessary for several fundamental cell processes. Their protective role against various abiotic stress factors has been reported in different plant species,while the mechanism by which polyamines act during plant-microbe i...

12/06/2017
Research Article

Numerical Simulation of Thrombotic Occlusion in Tortuous Arterioles

Zhi-Gang Feng*, Miguel Cortina, Jennifer KW Chesnutt and Hai-Chao Han*

Tortuous microvessels alter blood flow and stimulate thrombosis but the physical mechanisms are poorly understood. Both tortuous microvessels and abnormally large platelets are seen in diabetic patients. Thus, the objective of this study was to determine the physical effects of arteriole tortu...

12/05/2017
Case Report

Addiction to self-strangulation: a case-report

Aurely Ameller*, Yann Le Strat, Marion Cadranel, Celine Portalier and Caroline Dubertret

Introduction: DSM-5 mentions autoerotic asphyxia in the paraphilic disorders section, as a specifier for the diagnostic of sexual masochism disorder. Strangulation activities have also been observed in the “choking game”. The term “strangulation activity” is considered...

12/05/2017
Case Report

Near Complete Response to 177Lu- PSMA-DKFZ-617 Therapy in a Patient with Metastatic Castration Resistant Prostate Cancer

Madhav Prasad Yadav, Sanjana Ballal and Chandrasekhar Bal*

Prostate specific membrane antigen, a type II transmembrane protein is an excellent target for the radionuclide therapy in advanced prostate cancer patients due to its high expression in the prostate cancer cells.We present the case of a 69-year old man with advanced metastatic castration resi...

12/12/2017
Research Article

Influence of Vitamin E on the Disposition Kinetics of Florfenicol after single and multiple oral administrations in Broiler Chickens

Fatma Ibrahim Abo El-Ela*, Hossny Awad El-Banna, Manal B El-Deen and Tohamy MA

Investigation the influences of vitamin (vit) E over a period of 5 days on the pharmacokinetics of florfenicol after single and multiple oral administrations in broiler chickens. Total of 12 broiler chickens had been taken single and multiple oral administrations of florfenicol (30 mg/kg) alon...

12/01/2017
Research Article

Quantification of the pressures generated during insertion of an epidural needle in labouring women of varying body mass indices

Wee MYK*, Isaacs RA, Vaughan N, Dubey VN and Parker B

Objective: The primary aim of this study was to measure pressure generated on a Tuohy needle during the epidural procedure in labouring women of varying body mass indices (BMI) with a view of utilising the data for the future development of a high fidelity epidural simulator. ...

12/28/2017
Mini Review

Lipid-induced cardiovascular diseases

Sumeet Manandhar, Sujin Ju, Dong-Hyun Choi and Heesang Song*

Cardiovascular diseases are the leading cause of death worldwide. There are many evidences that the dysfunctioning lipotoxicity is the one of major factors of cardiovascular diseases such as, atherosclerosis, hypertension, and coronary heart disease. Obesity and diabetes increase circulating l...