Review Article

The continued relevance of Deep Brain Stimulation for chronic pain

Abstract

For the millions of patients experiencing chronic pain despite pharmacotherapy, deep brain stimulation (DBS) provides a beacon of hope. Over the past decade the field has shifted away from DBS towards other forms of neuromodulation, particularly spinal cord ...

Case Report

Preservation of Haemostasis with Anti-thrombotic Serotonin Antagonism

Abstract

An enquiry into the lack of attention awarded to serotonin antagonism in the treatment of arterial thrombosis revealed that the mode of action of serotonin and its platelet receptor antagonists was an action upon thrombus growth, and not, as with other anti-...

Review Article

The role of UK national ligament registry as additional source of evidence for anterior cruciate ligament reconstruction: Review of the literature and future Perspectives

Abstract

Background: There is paucity in studies reporting long-term results following anterior cruciate ligament (ACL) rupture. A UK national ligament registry (NLR) designed to collect demographic, clinical and outcome data on patients ...

Case Report

Otogenic lateral sinus Thrombosis: a rare complication of chronic Otitis media

Abstract

Since the advent of antibiotics, lateral sinus thrombosis is an infrequent complication of otitis media. Lateral sinus thrombosis may occur by thrombophlebitis or penetration by offending pathogens through the dura of middle and posterior cranial fossae. We ...

Short Communication

Characterisation of Delayed Onset of Muscle Soreness (DOMS) in the hand, wrist and forearm using a finger dynamometer: A pilot study

Abstract

Background: Experimentally-induced delayed-onset muscle soreness of large muscle groups is frequently used in as an injurious model of muscle pain. We wanted to develop an experimental model of DOMS to to mimic overuse injuries f...

Case Report

An Unusual Cause of Anterolateral Ankle Pain and Snapping

Introduction

Most patients with anterolateral ankle pain report some history of trauma as the precipitating event. In the majority of cases of anterolateral ankle pain with no history of trauma the cause is proliferative synovitis, especially in the area of the anter...

Case Report

The Risk-Adjusted Impact of Intraoperative Hemofi ltration on Real-World Outcomes of Patients Undergoing Cardiac Surgery

ABSTRACT

Objectives: The role of perioperative hemofiltration (HF) in adult patients with impaired renal function undergoing cardiac surgery is controversial. There are suggestions that it may be beneficial for high risk patients undergoi...

Case Report

Retrospective Analysis of Non-Contact ACL Injury Risk: A Case Series Review of Elite Female Athletes

Abstract

Background: Literature on ACL injury is limited when assessing for the presence and interaction of multiple risk factors simultaneously. Identifying risk factor interaction may increase the impact of prevention programmes to targ...