Prospective

Psychoanalysis of the doctrine of acute pneumonia

It is difficult to predict how the founder of psychoanalysis, Sigmund Freud, would react to an attempt to link his theory and the method of treating mental disorders based on it [1], with such a purely physical disease as acute pneumonia (AP).

Research Article

Characterization of the immune response in neuroimmune disorders in children

Abstract

Background: A misguided auto-reactive injury is responsible for several types of central nervous system (CNS) conditions in pediatrics. We propose that, in some of these conditions, the adaptive immune system has a common cellular immune pathogenesis, driven...

Case Report

pVAD-assisted left main DK-Crush Bifurcation PCI Post-ViV TAVR

Abstract

We describe successful percutaneous coronary intervention (PCI) of significantly diseased ostial left main (LM) and distal LM bifurcation (Medina 1,1,1) in a patient with a reduced left ventricular ejection fraction and a recent valve-in-valve balloon-expand...

Review Article

Will the pill help defeat the coronavirus?

The onset of the pandemic has caused widespread concern about the rapid spread of the infection and serious concern about the lack of specific treatment for it.

Review Article

Evidence-based primary care approach to treating people with COVID-19 infection to prevent life-threatening complications: A review of the evidence for practical application in a clinical setting

Abstract

The NIH has published treatment guidelines for treating COVID-19 patients in the hospital. However, as of this writing, there are no established protocols for treating COVID-19 positive patients in primary care. Accordingly, this investigator has taken on th...

Research Article

Environmental influence on blood serum detection using ultraviolet 365

Summary

The major use of alternative light sources (ALS) in the evaluation of bloodstains has been primarily focused on detection of whole blood, with relatively little attention to visualization of blood serum. Serum may become separated from blood pools during clot...

Research Article

Economic disparities and suicides: The dynamic panel data analyses of 50 states in the United States

Abstract

The economic inequalities associated with suicide risks among 50 states in the United States were identified in this paper to form the dynamic panel data set from 1981 to 2016. The effects of growing income inequalities on suicides in the Unites States were ...

Case Report

Cerebral arterial air embolism with anterior spinal cord syndrome after CT-guided hook-wire localization of Lung mass and pulmonary nodule

Abstract

Systemic arterial air embolism (SAAE) is a rare but serious complication of CT-guided hook wire localization of pulmonary nodule usually with catastrophic and poor outcome. Hook wire needle localization is done pre-operatively by placing wire around or into ...

Review Article

An update on outpatient competence restoration outcomes: The Washington DC Model

Abstract

This study provides an update to a previous study exploring time to restoration of adjudicative competence within an Outpatient Competence Restoration Program (OCRP). Authors examined the probability of restoration for individuals referred for outpatient com...

Research Article

Incidence and risk factors of vancomycin-associated acute kidney injury in a single center: Retrospective study

Abstract

Background: There is enough evidence to suggest that vancomycin increases the risk of acute kidney injury (AKI) but the exact mechanism is not well understood. This study aims to understand the incidence of vancomycin-associated acute kidney injury (VA-AKI) ...

Review Article

Chronic fatigue syndrome and epigenetics: The case for hyperbaric oxygen therapy in biomarker identification

Abstract

Chronic fatigue syndrome (CFS) is a poorly-understood respiratory condition that affects millions of individuals. Hyperbaric oxygen therapy (HBOT) is a treatment option being considered to address CFS as it is suggested to combat fatigue and increase oxygena...

Research Article

Helping asthmatic children through bonding therapy

Abstract

Disruptions in Maternal-infant Bonding are shown to be the mediating variable between maternal distress and the subsequent expression of childhood asthma. When the mothers’ bonding is repaired, their children’s asthmatic symptoms diminish...

Case Report

COVID-19: A unique opportunity for population health to align with nursing schools to help vulnerable populations at risk of adverse outcomes

COVID-9 created a public health crisis shutting down many normal day-to-day activities and adversely affecting life, as we know it.

Research Article

Association between obesity profile and non-alcoholic fatty liver by race/ethnicity

Abstract

NAFLD is characterized by accumulation of fat in the liver that can lead to health complications. Previous studies have found the obesity phenotype and its components to be risk factors for the development of NAFLD. This study aims to examine the relationshi...

Research Article

Parents’ perception of the school nurse’s role

Abstract

Background: School nurses possess an essential role in treating and helping children maintain health. However, the full scope of their role has not been identified by parents. Therefore, the purpose of this study was to explore parents’ perceptions o...

Case Report

Atlantoaxial subluxation in the pediatric patient: Case series and literature review

Abstract

Objective: Atlantoaxial subluxation (AAS) occurs when there is misalignment of the atlantoaxial joint. Several etiologies confer increased risk of AAS in children, including neck trauma, inflammation, infection, or inherent ligamentous laxity of the cervical...

Review Article

Packaging challenge for COVID-19 drug

At present Corona virus is the most burning topic across the world. At present there is no drug available to cure 100%. So many companies are trying to make it possible as soon as they can.

Case Report

Unusual presentation of Oxalate nephropathy causing Acute Kidney Injury: A case report

Abstract

Oxalate Nephropathy due to Hyperoxaluria and elevated serum oxalate level is a well-known cause for interstitial fibrosis, and ESRD. Conditions associated with high serum Oxalate, should be considered as a possible contributing factor for a patient&rsquo...

Research Article

Modification of the Renal Angina Index for identifying the need for renal replacement therapy in critically ill pediatric patients

Severe Acute Kidney Injury (AKI) is a common, serious problem affecting critically ill children that lacks effective treatment options. Currently, there are no treatment options for AKI other than supportive care. Continuous renal replacement therapy (CRRT) is employed to reduce Fluid Overl...

Case Report

COVID-19 related rhabdomyolysis

A novel coronavirus known as Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) with a high rate of human-to-human transmission has emerged, resulting in a worldwide public health crisis of catastrophic proportions. Common initial symptoms of Coronavirus Disease 2019 (COVID-19) in...

Review Article

Liver disease in the Era of Coronavirus Disease 19 (COVID-19) pandemic

Coronavirus infections have caused outbreaks in humans: SARS-COV ((Severe Acute Respiratory Syndrome) and MERS-CoV (Middle East Respiratory Syndrome) resulting in significant mortality and morbidity.

Research Article

Comparison of muscle activation of 3 different hip belt squat techniques

Abstract

The purpose of this study was to differentiate between muscular activity of three different types of belt squats (SquatMax-MD, Pit Shark and Monster Rhino) and the muscle activation of the rectus femoris, vastus medialis oblique, gluteus maximus, and gluteus...

Research Article

Universal testing for severe acute respiratory syndrome coronavirus 2 upon admission to three labor and delivery units in Santa Clara County, CA

Abstract

Objective: To determine the prevalence of patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in labor and delivery units in one of the epicentres of the West Coast.

Stud...

Review Article

The “Follow-up Factor” in management development

Leadership is not just for leaders anymore. Top companies are beginning to understand that sustaining peak performance requires a firm-wide commitment to developing leaders that is tightly aligned to organizational objectives — a commitment much easier to understand than to achiev...

Research Article

Targeted community outreach events to deliver healthcare to diverse rural populations

Abstract

Introduction: Rural populations often experience disparities in health and access to and quality of healthcare. Such disparities may differ among subpopulations. Community outreach events provide an opportunity for rural resident...

Review Article

Fibrinolytic therapy with tPA failed because it was based on a flawed concept

Abstract

Fibrinolytic therapy has become synonymous with tissue plasminogen activator (tPA) based on the belief that tPA alone was responsible for natural fibrinolysis. Although this assumption was belied from the outset by disappointing clinical results, it persiste...

Mini Review

Patients suffer when healthcare stocks rise

When a stock price rises or has a better P/E ratio, this is generally considered a measure of success. Is this true for health insurance stocks? Stock holders certainly are happy, but what about the purchasers of the carriers’ policies? Are patients smiling when the stock price go...

Review Article

Microbiome and Gastroesophageal Disease: Pathogenesis and Implications for Therapy

Abstract

There is growing evidence that gastroesophageal disease is influenced by the esophageal microbiome, and that commensal bacteria of the oropharynx, stomach, and colon are thought to have a role in modulatiing pathogenesis. These emerging hypotheses are based ...

Research Article

Trial of labor after cesarean outcomes with excessive gestational weight gain

Summary

The success of vaginal birth after cesarean section (VBAC) has been correlated with a variety of maternal characteristics such as age, ethnicity, and body mass index (BMI, calculated as weight in kilograms divided by height in meters squared). The patient&...

Research Article

Role of community health fairs in providing health services, improving health of rural residents

Abstract

Introduction: Obesity (BMI ≥ 30 kg m-2) is epidemic globally and is associated with increased risk for a wide range of physical and mental health comorbidities. This is a particular concern for rural residents who have a g...

Case Report

Case reports of observed significant improvement in patients with ARDS due to COVID-19 and maximum ventilatory support after inhalation of sodium bicarbonate

The emergence of COVID-19 worldwide in an unprecedented pandemic. COVID-19 has a significant mortality, mostly from acute lung injury. We reviewed the available literature from China and Europe in regard to the behavior of SARS-Cov2 and ability to adhere to the cell wall [1,2]. The evidence...

Review Article

Contemporary American stupidity

The American character is filled with contradictions and paradoxes [1], so it is understandable that, being susceptible to the imperfections, weakness and evils afflicting all peoples [2], it features its share and many types of injustices and stupidity.

Research Article

Neuroticism and BMI: The role of genetic tendency, behavior and environment on body weight

Abstract

Introduction: Recent research has explored the role that personality traits play in health and weight determination. This study extends current research by evaluating the extent to which behavior mediates the impact of neuroticis...

Research Article

A comparative study of solid waste management in the United States, Europe and Asia

Abstract

Managing municipal solid waste correctly is critical to the success of a society. Many regions and countries in the world are behind others in the context of solid waste management. In order to compare three such regions within this context, a meta-analysis ...

Research Article

Rural adolescent health: Issues, behaviors and self-reported awareness

Abstract

Purpose: The purpose of the study was to examine the health status of rural adolescents and young adults in the United States through a comprehensive review of detailed health information, behavior and health awareness. The dispa...

Opinion

PR and QT intervals short on the same electrocardiogram

In 2007, Professor Breijo-Márquez described an electrocardiographic pattern, consisting of the presence of a short PR interval (or PQ) together with a short QT interval in the same individual. It was published with the headline “Decrease in cardiac electrical systole&am...

Review Article

His bundle pacing in heart failure: A review of current literature

Abstract

Biventricular (BiV) pacing revolutionized the heart failure management in patients with sinus rhythm and left bundle branch block; however, left ventricular-lead placement is not always technically possible. Also, BiV pacing does not fully normalize ventricu...

Research Article

A quantum mechanical model for hole transport through DNA: predicting conditions for oscillatory/non-oscillatory behavior

Abstract

A quantum mechanical model that considers tunneling and inelastic scattering has been applied to explain the hole transfer reaction from a G (Guanine) base to a GGG base cluster through a barrier of Adenine bases, (A)n (n = 1-16). For &l...

Research Article

Sensitivity and Intertextile variance of amylase paper for saliva detection

Summary

Contemporary forensic science hinges on DNA analysis to link an individual to a crime scene. Sources of DNA include bodily fluids, including saliva. Amylase is a primary enzyme in human saliva and thus, if detected, indicates possible presence of human saliva...

Research Article

In vitro and preventative field evaluations of potential biological control agents and synthetic fungicides for control of Clarireedia jacksonii sp. nov.

Abstract

Clarireedia jacksonii sp. nov. Formerly Sclerotinia homoeocarpa F.T. Bennett, the causal agent of dollar spot (DS), is the most destructive pathogen in turfgrass. Symptoms appear as circular patches 10-40 mm in diameter with small tan lesions surrounded by a...

Research Article

Low sensitivity of the careHPV™ Assay for detection of Oncogenic Human Papillomavirus in cervical samples from HIV-infected and HIV-uninfected Kenyan women

Abstract

Background: Human papillomavirus (HPV) infection causes cervical cancer (CC), a common malignancy among Kenyan women. New CC screening methods rely on oncogenic HPV (“high-risk”, or HR-HPV) detection, but most...

Case Report

Granulomatosis with polyangiitis (GPA) in a 76-year old woman presenting with pulmonary nodule and accelerating acute kidney injury

Abstract

Granulomatosis with polyangiitis (GPA), a form of ANCA-associated vasculitis (AAV), is a rare disease with an often-occult presentation. It is more common in 4th and 5th decades of life but can be seen in all ages.

This case report deta...

Research Article

Uterine precursor lesions in patients with incidental nodal lymphangioleiomyomatosis: A report of 4 cases

Abstract

Uterine sections from 6 patients with incidental nodal lymphangioleiomyomatosis (LAM) were examined for LAM lesions by screening these sections with cathepsin K immunohistochemistry (IHC) stains. The hysterectomy specimens were all concurrent with the lymph ...

Review Article

The Neppe-Close triadic dimensional vortical paradigm: An invited summary

Abstract

Physicists are generally trained in the Standard Model of Physics (SMP). This implies that they perceive and account for only 3 dimensions of space in a moment in time (3S-1t) (a 4-dimensional [4D] model). However, applying the SMP, more than fifty significa...

Research Article

Aggressive hydration in early resuscitation phase does not provide mortality benefit in acute pancreatitis

Abstract

Introduction: Fluid management is the cornerstone of treatment for acute pancreatitis (AP), but the proper rate and volume is still controversial. We aim to evaluate the role of aggressive hydration in AP patients.

&...

Case Report

Embolic Septic Emboli with MRSA: A different source

Abstract

Septic Iliac vein thrombophlebitis with associated psoas abscess is a rare and severe entity, which diagnosis is challenging when no risk factor is clearly present. We are presenting a case of severe septic cavitary pulmonary emboli complicated with Acute Re...

Case Report

Brainstem Death due to hypertension induced brain hemorrhage

Introduction

Brain stem death is when a person has permanently lost the potential for consciousness and the capacity to breathe. When this happens, a machine called a ventilator keeps oxygen circulating through the person’s bloodstream - a person confirmed ...

Research Article

Long-Term Impact of Coronary Artery Disease in Lung Transplantation

Background: Adoption of the Lung Allocation Score (LAS) has led to increased listing of older patients and those with idiopathic pulmonary fibrosis (IPF) for lung transplantation (LTX). Older patients and those with IPF have higher prevalence of coronary artery ...

Case Report

First trimester growth delay: An early marker of triploidy

Introduction

Triploidy is one the most common chromosomal abnormality in humans, complicating about 1% of all human pregnancies. Most affected conceptions undergo spontaneous abortion in the first trimester, making the prevalence of second trimester triploidy low. Vi...

Research Article

Evaluation of outcomes of 8-week therapy with ledipasvir/sofosbuvir or glecaprevir/pibrentasvir in veterans with hepatitis C infection

Summary

Hepatitis C Virus (HCV) infection is usually treated with direct acting antivirals (DAAs) for 12 weeks. In treatment naive patients with genotype (GT) 1 infection without cirrhosis and baseline viral load <6 million, 8 weeks of Ledipasvir/Sofosbuvir (L...