Case Report

Single Trans apical access for double aortic and mitral valves-in-valves procedures with high risk of thrombus embolism

Background: Persistent left atrial thrombus remains a contra indication to transeptal valves in valves procedure. We aimed to perform a double valves in valves replacement through transapical access with cerebral angiography control during the procedure just after implantation...

Case Report

Eosinophilic otitis media and eosinophilic asthma: Shared pathophysiology and response to anti-IL5

Asthma is a highly prevalent airway disease with multiple phenotypes [1,2]. Adult-onset eosinophilic asthma is a severe asthma subtype associated with more frequent and severe exacerbations, the development of persistent airflow limitation and a poorer quality of life. This type of asthma is m...

Editorial

CRISPR genome editing: A general view

CRISPR technology has presented a path forward for genomic engineering and gene modification. The framework for the use of CRISPR technology to manipulate the human genome is of great interest and the form of its development and application has excited the researchers and biotech communities a...