Research Article

Aripiprazole-induced seizures in children with autism spectrum disorder and epilepsy

<h2>Abstract</h2> <p><strong>Purpose:</strong> Children with autism spectrum disorder are at an increased risk for developing seizures, which can be triggered by classical antipsychotics. Aripiprazole is an atypical antipsychotic that has a safer drug profile. The ob...

Review Article

Natural killer cells in patients with hematologic malignancies, solid tumors and in recipients of hematopoietic stem cell transplantation

<h2>Abstract</h2> <p>Natural killer cells represent the first line of defense against infections and tumors and can be derived from various sources including: bone marrow, peripheral blood, specific types of human stem cells, and certain cell lines. The functions of natural kill...

Research Article

Age Estimation Reports: Where do we stand?

<h2>Abstract</h2> <p>Age estimations process is not standardized worldwide. However, there is a wide agreement about the most suitable methods currently available. Up until now, the procedure of creating expert reports and to implement quality assurance in age estimation are var...

Editorial

The rising role of natural killer cells in patients with malignant hematological disorders and in recipients of hematopoietic stem cell transplantation

<h2>Introduction</h2> <p>Natural killer (NK) cells, the third population of lymphoid cells, comprise 5%-25% of peripheral blood (PB) lymphocytes and represent the first line of defense against infections and tumors [1-7]. They can be derived from: bone marrow, PB, cryopreserved ...

Review Article

Biologic therapy in severe asthma: An update

<h2>Abstract</h2> <p>Asthma is a chronic inflammatory disease of the airways characterized by airway inflammation, bronchial hyperresponsiveness, reversible airflow obstruction and recurrent symptoms. Patients often present with coughing, wheezing, dyspnea, and chest tightness, ...

Case Report

Severe Infantile Transaldolase deficiency: A case report

<h2>Abstract</h2> <p>Transaldolase TALDO deficiency is a rare autosomal recessive disorder of the pentose phosphate pathway. It has variable presentations with poor outcome when present early in life. We present a young Saudi infant with a fatal early presentation of TALD defici...

Research Article

The beneficial effects of varicella zoster virus

<h2>Abstract</h2> <p>Varicella zoster virus behaves differently from other herpes viruses as it differs from them in many aspects. Recently, there has been growing evidence on the beneficial effects of the virus in immune compromised hosts and these effects are translated into p...

Review Article

Idiopathic post-operative biliary duct system dilatation; potential etiology and management

<h2>Summary</h2> <p>What is called &ldquo;idiopathic biliary duct system dilatation&rdquo; or better to name it &ldquo;un-explained biliary dilatation&rdquo; is mostly following surgical procedures related to upper gastrointestinal and hepato-bilio-pancreatic sys...

Editorial

Varicella zoster virus: The potentially useful virus

<h2>Editorial</h2> <p>Varicella zoster virus (VZV), a double-stranded DNA virus, is a highly contagious human neurotropic virus that belongs to the alpha group of herpes viruses [1-4]. Primary VZV infection (chickenpox) occurs in childhood then the virus becomes latent in the ne...

Research Article

Alternate day outpatient hemodialysis schedule is the appropriate practical alternative schedule to improve patients’ outcomes

<h2>Introduction</h2> <p>The rise in all-cause and cardiovascular mortality and hospitalization rates among the hemodialysis (HD) patients after the long weekly inter-dialysis interval is very impressive. In fact, there is an additional long-term morbidity risk besides this acut...

Case Report

Reversal of pure red cell aplasia by varicella zoster virus infection

<h2>Abstract</h2> <p><strong>Background:</strong> Pure red cell aplasia is characterized by anemia, reticulocytopenia and diminished bone marrow erythroid precursors. It has multifactorial etiology and consequently several therapeutic interventions.</p> <...

Research Article

Perinuclear halo indicate Trichomonas vaginalis in Pap smear

<h2>Abstract</h2> <p>Trichomonas vaginalis could be seen in Pap smears where it is reported, but because main concerned is placed on malignant cells in Pap smears, not much effort is done to search for this parasite in smears. In this study, 100 cervical and vaginal specimens we...

Research Article

Best and effective practices of wound care and healing among patients with Diabetes Mellitus

<h2>Abstract</h2> <p><strong>Aim:</strong> With the continuing trend in the incidence of diabetic ulcer, the current researches on wound care and healing will bring best and effective practices on wound care and healing among patients suffering from diabetes mellitus...

Case Report

Lessons from the success and failures of peritoneal Dialysis-Related Brucella Peritonitis in the last 16 years: Case report and Literature review

<h2>Abstract</h2> <p>Brucellosis is a zoonotic infection that is endemic in some Mediterranean countries, North Africa and the Middle East. Brucella is a rare cause of peritonitis in Peritoneal Dialysis (PD) population and in non-dialysis patients alike. We report here a challen...

Research Article

Diagnostic accuracy of Magnetic Resonance Imaging to differentiate benign and Malignant Parotid Gland Tumors

<h2>Abstract</h2> <p><strong>Objective:</strong> To determine the diagnostic accuracy of Magnetic Resonance Imaging (MRI) to differentiate Benign and Malignant Parotid Gland Tumors taking histopathology as gold standard.</p> <p><strong>Place and ...

Case Report

Successful management of disseminated Fusarium infection in a patient with acute myeloid leukemia

<h2>Abstract</h2> <p><strong>Background</strong>: Invasive fungal infections cause significant morbidity and mortality in patients with hematologic malignancies and in recipients of hematopoietic stem cell transplantation.</p> <p><strong>Case<...

Research Article

Perinatal Morbidity and Mortality following repeat Cesarean section due to five or more previous Cesarean Section done in Tertiary centre in KSA

<h2>Abstract</h2> <p><strong>Objectives: </strong>To highlight and determine the maternal and neonatal outcome and associated risks for patients who have undergone their 6th and more caesarean sections.&nbsp;</p> <p><strong>Design: </stron...

Case Report

Biologic therapy-Related demyelinating peripheral neuropathy in a child with Juvenile Idiopathic Arthritis

<h2>Abstract</h2> <p>Demyelinating peripheral neuropathy has been described in association with tumor necrosis factor (TNF) inhibitors. It is rarely developed after treatment discontinuation. We present the case of a child with juvenile idiopathic arthritis who developed periphe...

Research Article

Maternal and fetal outcome of comparative study between old and adopted new value of screening of Gestational Diabetes Mellitus in tertiary centre in Saudi Arabia

<h2>Abstract</h2> <p><strong>Objectives:</strong> To check if there is any significant difference in the immediate outcome of pregnancy with diabetes using the new values of FBS &amp; 2hrs post prandial with 75g OGTT for 1 year (from 1st June 2013-31st May 2014) ...

Research Article

Screening of Gestational diabetes mellitus

<h2>Abstract</h2> <p>Gestational diabetes mellitus is becoming a very common medical disorder associated with pregnancy especially so in the Middle East and more so in Saudi Arabia, thus putting the women and fetuses at an increased risk of maternal and neonatal morbidity and mo...

Research Article

Radiological assessment of exposure doses and radon exhalation rates of building materials in Saudi Arabia

<h2>Abstract</h2> <p>In the present work, samples of building material are analyzed for their naturally occurring radioisotope activity such as uranium, radium, and radon. The radon emission rates, and the annual effective doses, &ldquo;AED&rdquo;, are also investigated....

Review Article

Promising Future in the Detection of Oral Cancer by Using Advance Screening Technology

<h2>Review</h2> <p>Oral cancer has a tendency to be detected at late stage which is detrimental to the patients because of its high mortality and morbidity rates (survival rate 15-50% [1]). The incidence of oral cancer worldwide is approximately 3% of all malignancies, thus crea...