Review Article

A retrospective review of the factors that negatively influenced the eradication of polio in South-South, Nigeria

Abstract

Background: The endemic nature of poliomyelitis in Nigeria was a source of concern to many given the global efforts aimed at eradicating the scourge. In this study, the factors that influenced the eradication of this malady in South-South Nigeria (Akwa Ibom ...

Research Article

Comparative efficacy of inspiratory, expiratory and combined respiratory muscle training on the pulmonary functions and chest expansion in acute stroke survivors

Abstract

Background: Respiratory muscle strength can be reduced in patients diagnosed with stroke, which reasonably justifies the use of respiratory muscle training in this population. This study determines the comparative efficacy of inspiratory, expiratory, and com...

Research Article

Open heart surgery in Nigerian children the need for international and regional collaboration: The Bayelsa and Enugu experience

Abstract

Background: Children with congenital heart diseases (CHD) often require palliative or definitive surgical heart interventions to restore cardiopulmonary function. Lack of early cardiac intervention contributes to large numbers of potentially preventable deat...

Case Report

Menstruating primary umbilicus cutaneous endometriosis: A case report and review of literature

Abstract

Primary umbilical cutaneous endometriosis is a rare umbilical endometrioma that affects women who are within the reproductive age group. It may be associated with infertility and severe dysmenorrhea and can be difficult to diagnosed in an asymptomatic patien...

Research Article

Determinants of health seeking behaviour of women with obstetric fistula in south- south and south east, Nigeria: A review of the impact of availability and quality of health care services through a cross-sectional study

Abstract

Background: Obstetric fistula is a condition that results from obstructed labour, which occurs when the baby cannot pass through the mother’s birth canal because it either does not come head first or is too large for her pelvis. Prompt medical inte...

Review Article

Sildenafil citrate in healthy and diseased hearts

Abstract

Sildenafil citrate is one of the frontline drugs used to manage erectile dysfunction (ED). Chemically, it is described as 1-[[3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H –pyrazolo [4,3-d]pyrimidin-5-yl)-4 ethoxyphenyl] sulfonyl]-4-methylpipe...

Research Article

Impact of amitriptyline on learning and memory

Summary

Background/aim: Amitriptyline belongs to class of known as tricycline antidepresant (TCA) that is being used to treat anxiety and depressive states. It may help improve mood and feelings of well-being, relieve anxiety and tension, help to improve sleep and in...

Research Article

Radionuclide contents in yam samples and health risks assessment in Oguta oil producing locality Imo State Nigeria

Abstract

Oguta LGA is surrounded by 44 oil wells located around different communities. Preliminary investigations indicated that crude wastes were not properly managed and oil spillage occurred regularly in the LGA. Therefore, assessment of both radionuclide contents...

Research Article

Comparative Osteometric study of some selected bones of local domestic turkey and guinea fowl

Abstract

The research was conducted in the Gross section of Veterinary Anatomy laboratory with the aim of preparation and comparing some skeleton bones of local domestic turkey and guinea fowl. Samples were purchased, sacrifice, feather and excess flesh were removed ...

Review Article

Explicating the presentations of Acanthamoeba keratitis with special concern in the COVID-19 pandemic ambient

Abstract

This article presents an overview of information regarding Acanthamoeba keratitis per epidemiology, host-pathogen interactions, clinical manifestations, risk factors, environmental implications, diagnosis, treatment and management as well as COVID-19 charact...

Research Article

The clinicopathological correlates of Cystoisosporiasis in immunocompetent, immunocompromised and HIV-infected/AIDS patients, but neglected in SARS-CoV-2/COVID-19 patients?

Abstract

Cystoisosporiasis (formerly isosporiasis) is caused by Cystoisospora belli (erstwhile named Isospora belli) is encountered globally, particularly in tropical and subtropical regions. Cystoisosporiasis is a human intestinal disease whose etiology is the paras...

Letter to the Editor

Seasonal change and COVID-19: Will the harmattan season lead to an increase in COVID-19 cases in Nigeria?

Abstract

The harmattan season, which is a period characterized by low temperature, dry air and increased air pollution leads to widespread airborne disease and exacerbation of pre-existing conditions, should be recognized as a period of potential risk of high COVID-1...

Research Article

Effect of ginger flour supplementation on fermented millet flour ‘ibyer’ anti-diabetic and biochemical properties

Abstract

COVID-19 is a mucoso-respiratory highly contagious disease that has leaded to a tremendous globFermented millet flour (ibyer) is an indigenous non-alcoholic gruel made from cereals either (maize, sorghum and millet). It is prepared by cooking reconstituted c...

Research Article

Awareness level on the role of forensic DNA database in criminal investigation in Nigeria: A case study of Benin city

Summary

Pieces of evidence have continued to emerge, demonstrating the extensive efficiency and effectiveness of the DNA database in assisting criminal investigations around the world. Therefore, the present study aimed to determine the awareness level on the promine...

Research Article

A study of 12c +12c nuclear reaction using a new M3Y-type effective interaction

Abstract

This paper is a study of nuclear reactions involving 12C + 12C nuclei carried out with a heavy-ion nucleus-nucleus optical potential derived from a new M3Y-type effective interaction, called B3Y-Fetal, within the framework of optical model at the incident en...

Research Article

Determination of antibiotics susceptibility profile of Shigella species isolated from children with acute diarrhea

Abstract

Diarrheal diseases continue to be the major cause of morbidity and mortality among children under 5 years. This study aimed to isolate, identify and determining the prevalence, antimicrobial susceptibility profile of Shigella sp associated with acute diarrhe...

Rapid Communication

Utilization of midwives service scheme among women farmers in Southwestern Nigeria

Abstract

Maternal mortality accounts for most deaths in agrarian communities of Nigeria due to poor access to midwives services and inadequate Skilled Birth Attendants (SBAs). The Midwives Service Scheme (MSS) was established to engage more SBAs and advocate better u...

Research Article

Efficacy of transcranial direct current stimulation and over-ground walking task on functional mobility and quality of life of stroke survivors

Abstract

Introduction: High proportion of stroke survivors have impaired functional mobility and decrease in overall quality of life (QoL). Transcranial direct current stimulation (tDCS) (non-invasive brain stimulation) and over-ground walking task (OGWT) (functional...

Research Article

Identification and resolution of drug therapy problems among hypertensive patients receiving care in a Nigerian Hospital - A pilot study

Abstract

Background: An event involving drug therapy that actually or potentially interfers with the desired health outcomes is known as drug therapy problem.

Objective: The study aimed t...

Research Article

Knowledge, attitude and practice towards hypertension among patients receiving care in a Nigerian Hospital

Abstract

Background: Poor knowledge about hypertension can lead to poor attitude towards the disease which may directly affect patients self-care practices towards hypertension.
Objective: This study aimed to assess the knowl...

Research Article

Clinical profile and surgical outcomes of children presenting with teratology of Fallot

Abstract

Background: Tetralogy of Fallot (TOF) is a very common cyanotic congenital heart disease presenting early at birth with various degrees of cyanosis. If left uncorrected surgically, can lead to death.

Research Article

Measurement of background ionizing radiation in the federal university of technology owerri, Nigeria using calibrated digital geiger counter

Abstract

The measurement of the natural ionizing radiation in the Federal University of Technology Owerri, Nigeria was carried out using a well calibrated Digital Geiger Muller counter models GCA – 04w. Measurements were taken randomly in thirty (30) diff e...

Research Article

Assessment of cardiovascular and renal functions during treatment with Desmodium adscendens therapy

Abstract

Desmodium adscendens is a rain forest medicinal herb used in managing quite a number of medical conditions. Its efficacy in the treatment of several diseases has made it a first line herb for doctors, especially in managing all forms of spasm. It is however ...

Research Article

Quality Evaluation of Sorghum bicolor Stem Sheath Enriched with Spondias mombin Extract

Abstract

The nutritional compositions of sorghum stem sheath-Spondias mombin extract were evaluated. The enriched stem sheath extract were obtained by mixing sorghum stem sheath and Spondias mombin (iyeye) extract in varied proportions at 100:0; 0:100; 95:5; 90:10 an...

Research Article

Socio-demographic characteristics and other factors associated with depressive illness among medical students at the University of Port Harcourt

Abstract

Background: The burden of depression as a mental disorder has continued to increase and constituting an enormous public health concern among all age groups. A number of socio-demographic, and other factors including a stressful a...

Research Article

Risk evaluation and modeling of soils contaminated with Polycyclic Aromatic Hydrocarbons (PAHs) in parts of Bonny Island, Niger Delta, Nigeria

Abstract

Environmental impact of a recent oil spill incident in Bonny terminal using soil media was studied using a risk-based modeling approach. The establishment of the presence of contaminants of concern (CoC), evaluation/assessment, modeling spilled volume and as...

Mini Review

Role of T-Helper cells (CD4+ T Cells) in human immune system against some microbial infection: A mini review

Abstract

The human immune system consists of innate and adaptive immune responses which both provide protective immunity to microbial infection. The adaptive immune system consists of T and B cell which act as second line defense through production of neutralizing an...

Case Report

Pathological left ventricular hypertrophy and outflow tract obstruction in an infant of a diabetic mother: A case report

Abstract

Background: Infants of diabetic mothers (IDMs) are at increased risk of developing congenital anomalies including cardiac defects. Pathological left ventricular hypertrophy, asymmetrical septal hypertrophy and outflow tract obstr...

Research Article

Anatomical changes of the development of red Sokoto goat stomach

Abstract

This study is aimed at investigating the age related changes in postnatal development of red Sokoto goat stomach. In this study, a total of ten red Sokoto goat digestive tract samples were used and they were grouped into five (5) age categories (group A to E...

Research Article

Common reproductive problem associated with one humped camel (Camelus dromedarius) in West Africa

Abstract

The problems of reproduction in the camel are not extensively investigated as in the bovine, caprine and ovine species. There is need to elucidate the problem in detailed in order to overcome the problem of production and genetic multiplication. The informat...

Research Article

Analysis of factors influencing participation of farm households in watermelon production in some selected local government areas of Sokoto State, Nigeria

Abstract

The study analyzed the factors influencing participation of farm households’ in watermelon production in the study areas. Three local government areas out of Sokoto state were purposively selected. Questionnaire was used to collect data. Multistage...

Research Article

Demographic pattern of refractive anomalies in Niger Delta presbyopes - Implications for preventive eye care practice

Abstract

Background/Aim: In spite of global initiatives to provide sight for all by the year 2020, many middle-aged to elderly people in the Niger Delta still have significant visual impairment due to uncorrected refractive errors. The ai...

Research Article

Oral Clindamycin and Metronidazole in the treatment of bacterial vaginosis in pregnant black women: Comparison of efficacy and pregnancy outcome

Abstract

Bacterial vaginosis (BV) is associated with adverse pregnancy outcomes with various treatment options.

Objective: To compare the efficacy and effect on pregnancy outcome of Metronidazole and Clindamycin in w...

Research Article

Burden of hearing loss in Subsaharan Africa: Snapshot from an ENT clinic in Nigeria

Summary

Background: Disabling hearing loss is a prevalent public health issue, with significant impact on patients’ communication. The disability associated with hearing loss depends on the severity of the hearing loss. There ar...

Research Article

Nutritional analysis of Sphenostylis Stenocarpa seeds partially included with soya bean meal in Heterobranchus Bidorsalis fingerling diet

Abstract

Five experimental feeding trials were conducted to investigate the performance of Heterobranchus bidorsalis fingerlings to graded levels (0, 25, 50,75 and 100%) of Sphenostylis stenocarpa seed meal diets. Complete randomized design with triplicate groups of ...

Research Article

Postgraduate students’ perception of the educational environment of a wet lab training in Neurological Surgery Division, UCH, Ibadan

Summary

Objective: The importance of understanding the perceptions of medical students to their training environment cannot be overemphasized. The study evaluated the wet lab training organized for Senior Registrars in the Neurosurgery, D...

Research Article

Perceived causes and prevention of catheter-associated urinary tract infections among spinal cord injured patients

Summary

Catheter-associated urinary tract infection (CAUTI) is among the most common nosocomial infections especially in acute care settings. Its economic and unanticipated health implications make it burdensome for the healthcare providers and patients. The paper ex...

Research Article

Prevalence of congenital heart diseases among primary school children in the Niger Delta Region of Nigeria, West Africa

Abstract

Introduction: Congenital heart diseases (CHD) are leading causes of childhood morbidity and mortality especially in developing countries. Community-based studies are important in ascertaining the burden of the disease.

...

Review Article

Timing of cardiac surgery and other intervention among children with congenital heart disease: A review article

Abstract

Background: Early diagnosis and improved facilities are necessary for determining the optimal timing of surgery and other interventions in children with congenital heart diseases in Nigeria. This is because late presentation, lat...

Research Article

Comparison of selected lower limb biomechanical variables between university of ibadan sportsmen with and without patellofemoral pain syndrome

Abstract

Patellofemoral pain syndrome is common among athletes who participate in jumping, running and pivoting sports. The aim of this study was to compare selected lower limb biomechanical variables between University of Ibadan students (athletes) with and without ...

Research Article

Effect of Khaya Senegalensis Bark and Oil on Post-Harvest Fungal Agents of Groundnut Seeds Rot in Adamawa State, Nigeria

Abstract

Standardized method of seed treatment is of prime importance in the production of groundnut. The study was to carry out control trial using bark extract (aqueous and ethanol) and oil (seed) of mahogany (Khaya senegalensis) on seven (7) isolated fungi from tw...

Research Article

Causal agents of Post-harvest Rot of Pumpkin (Cucurbita pepo L.) and their control using Indigenous Practices in Hong, Adamawa State

Abstract

Pumpkins (Cucurbita pepo) are grown all around the world for a variety of reasons ranging from agricultural purposes to commercial and ornamental sales. The pathogens causing the rot of pumpkin in the world include fungi, bacteria, and viruses. The study was...

Case Report

Anasarca in a 35 year old man- A diagnostic dilemma

Anasarca is generalized swelling of the body following accumulation of fluid in the extracellular compartments. It may result from multiple aetiology mainly of renal, hepatic or cardiovascular origin. 

The aim of this case report is to highlight the challenges encountered in ma...

Research Article

Complications of Internal jugular catheters in haemodialysis patients at a kidney care center in Nigeria

Abstract

Internal jugular vein catheters (IJC) is recommended as the central venous access of choice in haemodialysis patients. However it is associated with complications of variable severity.

Objectives: To study t...

Research Article

Maternal mortality and factors affecting it, among pregnant women in Abeokuta South, Nigeria

Abstract

This observational study assessed the knowledge of pregnant women attending antenatal clinics at two selected hospitals in Abeokuta South, Nigeria on the causes and risk factors of maternal mortality, identified barriers to knowledge acquisition, and examine...

Research Article

Demographic survey and management outcome of Post-Neonatal Tetanus at the Ekiti state university teaching hospital, Ado Ekiti

Abstract

Background: Tetanus continues to threaten the survival of children in spite of it being a vaccine preventable disease. The objective of this study was to determine the prevalence of post-neonatal tetanus, review the vacc...

Review Article

Topical Management of chronic rhinosinusitis - A literature review

Introduction

Chronic rhinosinusitis (CRS) is an inflammatory condition involving nasal passages and the paranasal sinuses for 12 weeks or longer [1]. It can be subdivided into three types: CRS with nasal polyposis (CRS with NP), CRS without nasal polyposis (CRS witho...

Research Article

The pattern of blood pressure and renal function among children with Sickle Cell Anaemia presenting in a tertiary health institution in Nigeria

Abstract

Background: In sickle cell anemia (SCA), compromise of the renal vasculature due to sickled red cells has been recognized.

Objectives: To assess the renal function and blood pres...

Research Article

Challenges of haemodialysis: A single centre experience in South West Nigeria

Abstract

Background: Haemodialysis is the commonest method of Renal Replacement Therapy in Nigeria. Despite an advancement in the technicality and better understanding of haemodialysis, a number of complications are known to be associated...

Research Article

Lemongrass tea consumption and changes in Acid-Base Balance and Electrolyte homeostasis

Abstract

The consumption of dietary herbs and supplements may be associated with several physiological consequences including, but not limited to disturbances of acid-base homeostasis, minerals and electrolytes wasting, gastrointestinal disturbances as well as hemody...