Research Article

Galenic hospital laboratory during COVID-19 emergency: A practical experience in an advanced country

<h2>Abstract</h2> <p>In the actual COVID-19 emergency, as pandemic disease, in many countries at the same time there was the rapid need to use preventive and therapeutic measures to control the diffusion of infection.</p> <p>In PC AREA (Italy north) in the period ...

Research Article

Percutaneous abdomino-pelvic abscess drainage in complicated Crohn’s disease

<h2>Abstract</h2> <p>Purpose: Percutaneous abscess drainage (PAD) is the first-line approach for abscess in Crohn&rsquo;s disease (CD) since it procrastinates or avoids surgery especially in postoperative abscesses [within 30 days post-operative (p.o.)]. We retrospectively e...

Case Report

A mild form of Familial Mediterranean Fever associated with a polymorphisms C.NT 1588,-69G>

<p>Familial Mediterranean fever (FMF) is an autosomal recessive autoinflammatory disease caused by mutation(s) in the Mediterranean fever (MEFV, pyrinmarenostrin) gene [1,2].</p>

Case Report

Epiphora as a sign of unexpected underlying squamous cell carcinoma within sinonasal inverted papilloma

<p>Sinonasal inverted papilloma (SIP) is a benign tumor which originates from the sinonasal Schneiderian mucosa and accounts for 0.5% to 4% of all nasal and sinus neoplasm [1]. Pathologically, SIP epithelium inverts into submucosal stroma, which is different from other types of nasal papilloma...

Opinion

Management of gestational diabetes during ‘COVID19 time’

<h2>Abstract</h2> <p>The measures put in place by many governments around the world to fight the spread of COVID-19 have drastically reduced visits to diabetes centres. To keep providing people with diabetes the professional support they need and reduce the inconvenience caused ...

Case Report

Chronic subdural haematoma associated with arachnoid cyst of the middle fossa in a soccer player: Case report and review of the literature

<h2>Abstract</h2> <p><strong>Introduction:</strong> Arachnoid cyst (AC) is a congenital, benign, extra-axial lesion often found incidentally on intracranial imaging and makes up almost 1% of all intracranial masses. It arises from the splitting of arachnoid membranes...

Review Article

Evolutive immunologic and toxicologic approach in some neuroinflammatory and degenerative disease like SM, DA, PD: Imaging and Brain Wasting System clearance efficacy

<h2>Abstract</h2> <p>In order to better understand some neurologic degenerative process is fundamental to use also an evolutionary approach of vertebrates and especially in mammalians. Aim of this work is to verify if an objective measure of brain wasting system can help in this...

Research Article

In vitro antimicrobial activity of a black currant oil based shampoo versus a chlorhexidine 4% shampoo on bacteria strains isolated from canine pyoderma: A comparative study

<h2>Summary</h2> <p>Over the last few years, antimicrobial shampoo therapy has been increasingly used to treat skin infections in order to reduce systemic use of antibiotics. This study was aimed to compare the in vitro bactericidal effect of a black currant oil based shampoo (S...

Research Article

Persistent hydronephrosis after pyeloplasty: Is it a true obstruction? The role of endourology

<h2>Abstract</h2> <p><strong>Introduction:</strong> Anderson-Hynes pyeloplasty remains the gold standard in the treatment of ureteropelvic junction obstruction. The diagnostic criteria for defining the failure of pyeloplasty are not well-defined or even arbitrary. Li...

Case Report

CT perfusion-guided endovascular treatment of symptomatic cerebral vasospasm in a patient with perimesencephalic non-aneurysmal subarachnoid hemorrhage

<p>Symptomatic vasospasm represents an uncommon complication of perimesencephalic nonaneurysmal subarachnoid hemorrhage (SAH) which is a benign form of SAH without any recognizable source of bleeding accounting for about 15% of non-traumatic SAH [1,2].</p>

Review Article

Primary prevention of SCD with ICD in the elderly

<p>Implantable cardioverter defibrillators (ICDs) are electronic devices that can prevent sudden cardiac death (SCD) caused by arrhythmic events in patients.</p>

Opinion

Hypothesis about pathogenic action of Sars-COV-2

<h2>Abstract</h2> <p>The Hypothesis born on a simple clinical data noted by some Chinese Reserchers during the starting point of epidemic began in the dicember of the 2019, for the novel member of human coronavirus, officially named as SARS‐CoV‐2 (severe acute respiratory sy...

Research Article

Neuroanatomical profile of hemineglect in patient’s body image modification

<h2>Abstract</h2> <p><strong>Background:</strong> NSU is generally caused by right cerebral hemisphere lesions with a preeminent localization on the frontoparietal lobe.</p> <p><strong>Aim:</strong> To assess the correlation between the typ...

Research Article

Using correlative microscopy for studying and treatment of Mycoplasma infections of the ophtalmic mucosa

<h2>Abstract</h2> <p><strong>Purpose:</strong> We have studied in 18-month 21 patients showing kerato-conjunctivitis and/or dermato-blefaritis, where we will find a constant presence of mycoplasma in SEM optical cytology samples. The 21 patients were divided as follo...

Case Report

Symptomatic cluster-like headache in Normal-Pressure Hydrocephalus (NPH) and possible arteritis: Case report and an overview of the literature on secondary cluster-like headaches

<h2>Background</h2> <p>Cluster headache (CH) is a primary headache belonging to the group of trigeminal-autonomic cephalalgias, characterized by short attacks of very severe headache, always involving the same side of the head, more frequently localized to the periorbital and te...

Short Communication

Raw materials criticalities in material selection & design

<h2>Abstract</h2> <p>Circular Economy, Sustainability, Design for Environment are some of the keywords that identify new formidable challenges to be faced in the next years. Raw materials have a dominant role in reaching that goal. Green energy, electric vehicles, communication,...

Research Article

Benign Paroxysmal Positional Vertigo (BPPV) and microvasculitis: A comparative study between nasal cytology and pathology

<h2>Abstract</h2> <p><strong>Purpose:</strong> Benign paroxysmal positional vertigo (BPPV) is the most frequent peripheral vertigo syndrome in otoneurological clinical practice and is characterized by short and paroxysmal objective vertigo crises caused by changes in...

Case Report

Scraping cytology and scanning electron microscopy in diagnosis and therapy of corneal ulcer by mycobacterium infection

<p><strong>Purpose:</strong> This work is aimed at demonstrating that scraping cytology and scanning electron microscopy can successfully assist in the diagnosis of nontuberculous mycobacteria infection. For this purpose, we report the use of both these techniques in the diagnosis ...

Research Article

Gaucher’s disease and liver involvement: A review and our experience

<h2>Abstract</h2> <p><strong>Background:</strong> This article reviews current knowledge of Gaucher&rsquo;s disease (GD) and liver involvement and reports our experience: how many patients with chronic liver disease of unknown origin could be affected by Gaucher&...

Research Article

Innovative results in the treatment of inespecific anusitis-proctitis with the use of bergamot gel (Benebeo gel)®

<h2>Introduction</h2> <p>Inflammation is a complex biological reaction induced by the alteration of tissue homeostasis, which occurs in response to the presence of a biological, chemical or physical agent in the body [1]. The acute inflammatory response is composed of an elabora...

Case Report

Automatic heartbeat monitoring system

The proliferation and popularity of open source hardware and software, such as Arduino and Raspberry PI, together with IoT and Embedded System, has brought the health industry to rapid evolution, creating portable and low-cost medical devices for monitoring vital signals. Electrocardiographic ...

Research Article

The association between hypoxia, chronic ischemia and alters prostate structure and progress of chronic prostatic disease

<h2>Abstract</h2> <p>Chronic prostatitis today show high level of relapses and recurrent pathological events even if using the best pharmacological therapy. A better understanding of physiopathological effect of ischemic hypoxic condition (pelvic, prostate tissue) and the lympha...

Review Article

Advances in the use of GABAergic interneurons for the treatment of epilepsy

<h2>Abstract</h2> <p>Forebrain GABAergic neurons, the main inhibitory type of neuron in the cortex and hippocampus, represent a highly heterogeneous cell population that has been implicated in the predisposition to epilepsy and the onset of seizure. Earlier attempts to restore i...

Review Article

Essential thrombocythemia: Biology, clinical features, thrombotic risk, therapeutic options and outcome

<h2>Abstract</h2> <p>Essential Thrombocythemia (ET) is currently classified as a Philadelphia negative myeloproliferative neoplasm (MPN) together with polycythemia vera (PV) and primary myelofibrosis (PMF); the latter can be further divided in pre-fibrotic primary myelofibrosis ...

Research Article

The turing machine theory for some spinal cord and brain condition, A toxicological - antidotic depurative approach

<h2>Abstract</h2> <p>Aim of this work is to produce a general theory related an new depurative strategy to be devalued for reduce or delay some spinal cord and brain degenerative and inflammatory chronic disease or acute traumatic condition. It is used and informatics approach i...

Short Communication

Not-motorized Implantable Cardiac Assistance (NICA): Hemodynamic concepts and clinical perspectives

<h2>Abstract</h2> <p>The considerable improvements in cardiac support systems technologies have not solved until now the problem of connecting the cardiac assistance devices (CAD) to external energy sources, which makes these Patients at risk of lethal infections and dependent o...

Research Article

Postural and Kynematic effect of a new custom-made foot insole called “Prodynamic” in a cohort of patients affected by extrapiramidal disease

<h2>Abstract</h2> <p><strong>Background</strong>: The use of a custom-made orthotic plantar device is referenced as a true sensor-motor facilitation tool for the control of the postural orthostatic and orthodynamic position in patients with Parkinson&rsquo;s dise...

Case Report

A successful case report in woman: A gender medicine?

<h2>Abstract</h2> <p><strong>Introduction: </strong>Abdominal hernia is a pathological condition resulting from abnormal protrusion of abdominal viscera. In particular, internal hernias (IH) represents about 0.2-0.9% of all cases with para- duodenal hernias while obt...

Research Article

Role of plants, environmental toxins and physical neurotoxicological factors in Amyotrophic lateral sclerosis, Alzheimer Disease and other Neurodegenerative Diseases

<h2>Abstract</h2> <p>Aim of this work is to verify the effect of some neurotoxins, physical factors and geography in presentation of some Relevant Neurological disorder like some form of ASL, PD, AD.</p> <p>The geographic diffusion of the ASL/PD in west pacific (G...

Case Report

Squamous cell carcinoma developed on neglected, mistreated and delayed diagnosed chronic venous leg ulcer

<h2>Abstract</h2> <p>Chronic venous leg ulcers (VLU), especially long-lasting non-healing ulcers, are among the risk factors for squamous cell carcinoma (SCC) with particularly aggressive behaviour. We present a case of a 71-year-old female patient with a relevant personal histo...

Research Article

Endogenus toxicology: Modern physio-pathological aspects and relationship with new therapeutic strategies. An integrative discipline incorporating concepts from different research discipline like Biochemistry, Pharmacology and Toxicology

<h2>Abstract</h2> <p>Many pathologic disease can be considered as related to an Endogenous toxicological moves and in time dependent way (kinetics and dynamic of the process). In this work starting from the analysis of relevant literature involved with different disease and rela...

Research Article

TRIA-MF protocol as an innovative tool in the comprehensive treatment and outcome evaluation of lower limb amputees before and after prosthesis use

<h2>Abstract</h2> <p><strong>Background:</strong> A structured multidisciplinary team is very important during every phase of the amputation process and a good communicative team guarantees a greater tranquility for the patient, thanks to more homogenous information,...

Research Article

Endogenous archeological sciences: Physiology, Neuroscience, Biochemistry, Immunology, Pharmacology, Oncology and Genetics as instrument for a new field of investigation? Modern global aspects for a new discipline

<h2>Abstract</h2> <p>In this work is analyzed scientific literature involved in human evolution to be used as an archeological Pathway to link different sciences in an overall new discipline.</p> <p>A rational classification of single evidence make possible to bet...

Research Article

Receptor pharmacology and other relevant factors in lower urinary tract pathology under a functional and toxicological approach: Instrument to better manage antimicrobials therapy

<h2>Abstract</h2> <p>In various patients conditions involved in lower urinary tract disease LUT (like overactive bladder, bladder neck sclerosis, dis &ndash;synergy (with our synenrgic contraction between bladder detrusor and bladder neck, BPH, recurrent cysytitis, interstit...

Research Article

Influence of an integrated rehabilitative treatment on the modification of body representation in patients affected by Unilateral Spatial Neglect

<h2>Abstract</h2> <p><strong>Background:</strong> In line with the so-called &ldquo;embodiment concept&rdquo;, human bodily experience is characterized by the immediate feeling that our body is localized in a certain position in space and that the self is loc...

Review Article

Neuroscience, Rehabilitation and New Technologies: Perspectives and critical points for a synergistic development

<h2>Forewords</h2> <p>The growth of Rehabilitation, in all of its field and mainly in neuro-rehabilitation applications and settings, is showing increasingly strong interaction with the growth of technology and its innovative applications.</p> <p>Nevertheless, is ...

Case Report

Hyperkalemia: An archenemy in emergency medicine. Description of two case reports

<h2>Abstract</h2> <p>Potassium is an important ion capable to maintain intra-extracellular electric gradient. Variations in the intra-extracellular ionic flow may alter cells functions, skeletal and smooth muscle contractility and electric activity of myocardial cells.</p>...

Opinion

COPD and low plasma vitamin D levels: Correlation or causality?

<h2>Opinion</h2> <p>Chronic obstructive pulmonary disease (COPD) is the third leading cause of death and its prevalence and incidence is also related to smoking behavior [1]. COPD is still a chronic inflammatory and progressive disease caused by multifactorial agents including e...

Research Article

Amyotropyc Lateral Sclerosis and Endogenous -Esogenous Toxicological Movens: New model to verify other Pharmacological Strategies

<h2>Abstract</h2> <p>In 1874 J.M. Charcot was the first to describe ALS amyotrophic lateral sclerosis, a disease with an high non response therapy rate also to the actual therapy.</p> <p>ALS is not clearly associate to only single etio-patogenetic movens but many ...

Case Report

Herpes simplex virus (HSV)-1 encephalitis can induce chronic anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis

<h2>Abstract</h2> <p>Herpes simplex virus (HSV)-1 encephalitis is the most common infectious cause of sporadic encephalitis. Despite treatment with acyclovir, HSV encephalitis is still associated with severe morbidity characterized by persistent neurological deficits.&nbsp;H...

Case Report

Incidental findings in traditional nuclear medicine practice

<h2>Abstract</h2> <p>The presence of an&nbsp;incidental finding, defined as an abnormality which is unrelated to the initial scanning indication, is widely increases due to the access to new devices and imaging modalities. This growing number of incidental findings can lead ...

Research Article

Mindset kinetics and some depression status: A new quantitative model under biochemical - toxicology approach?

<h2>Abstract</h2> <p><strong>Depression:</strong> According Pubmed Health: Depression is a state of low mood and aversion to activity that can affect a person&rsquo;s thoughts, behavior, feelings and sense of well-being (moderate or severe).</p> <p>...

Research Article

Similarity between Some Biological Systems, Organotropism and Metastatic Process: Active Role Played By Secondary Organ?

<h2>Abstract</h2> <p>According to literature, about 90% of death from cancer is related to metastasis. Metastatic process present many similarity to some other biological processes. Once we have examined some relevant biomedical literature, by understanding the real causes of me...

Research Article

Perceptive and Rehabilitative Muscle Recruitment Facilitation Secondary to the use of a Dynamic and Asymmetric Spine Brace in the treatment of Adolescent Idiopathic Scoliosis (AIS)

<h2>Abstract</h2> <p><strong>Background</strong>: Supporting our adolescent people in realizing his/her self ability to reorganize and to establish a cross-linked paraspinal muscle control can be considered the most effective approach for muscle rehabilitation in ado...

Research Article

Brain and immune system: KURU disease a toxicological process?

<h2>Abstract</h2> <p>Starting from observation of pathogenesis of KURU disease we try to investigate the immunologic role played by central nervous systems. A deeply knowledge in the transmission model of this pathology can be an imaging/diagnostic tool to Verify the progression...

Research Article

The Immunitary role in chronic prostatitis and growth factors as promoter of BPH

<h2>Abstract</h2> <p>In the actual medical therapy of BPH, we can see: antibiotics, alpha blockers, 5-ARI, fitotherapeutics/natural products (Serenoa repens) with different which display clinical activities and other molecules such as FANS (local or systemic dosage forms) cortis...

Research Article

Bergamot Polyphenolic Fraction supplementation improves metabolic balance, endothelial function and maximal oxygen uptake in athletes

<h2>Abstract</h2> <p><strong>Background:</strong> The study aimed to evaluate the effects of a 4-week Bergamot Polyphenolic Fraction (BPF Gold; Bergamet Sport) supplementation on serum nitric oxide (NO), asymmetric dimethyl-arginine (ADMA), Endopat indices of endothe...

Research Article

Vestibular-limbic relationships Brain mapping

<h2>Abstract</h2> <p>Vestibular disorders and anxiety are closely related, probably because they share some neuronal pathways. Ageing and patient comorbidities are important facilitating factors, and multiple vascular risk factors could contribute to the onset of a vestibular sy...

Review Article

New pharmacological strategies in some metabolic endocrine disorder under a toxicological approach

<h2>Abstract</h2> <p>In this review After Observing biomedical literature (starting from some heart disease) results that some pathological phenomena are deeply involved in some metabolic endocrine condition: Kinetics and gradients in metabolism, catabolism, time related, toxic ...

Case Report

May we feed cancer?

<h2>Abstract</h2> <p>The patient with an oncological disease presents a series of discomforts related to the psychological sphere such as depression, pain, sense of usefulness, anger, but also inconveniences related to food sphere. Neoplastic disease interferes with eating behav...