Mini Review

Bleeding complications at the access sites during catheter directed thrombolysis for acute limb ischaemia: Mini review

Abstract

Acute and subacute ischemia of the lower limbs represents a major emergency with a high in-hospital mortality, complication, and leg amputation rates.

Treatment options for acute limb ischemia include systemic anticoagulation, followed ...

Review Article

Polyolefin nanocomposites based on metallocene catalysts

In recent years polyolefin nanocomposites are of great interest because of their high potential as materials with novel properties [1,2].

Research Article

Induction therapy with Erlotinib (E) and Gemcitabine/Platinum (GP) in stage III NSCLC

Abstract

Background: In 2004 we started a phase II trial in non-small lung cancer (NSCLC), stage III, with erlotinib followed by a combination with a platinum-based doublet in unselected patients to identify molecular subgroups benefitting from an EGFR targeting appr...

Research Article

Evidence of woven bone formation in carotid artery plaques

Abstract

Objective: Plaque morphology plays an important prognostic role in the occurrence of cerebrovascular events. Echolucent and heterogeneous plaques, in particular, carry an increased risk of subsequent stroke. Depending on the quality of the plaque echogenicit...

Letter to the Editor

COVID-19 and taking care and protection of patients with intellectual disabilities, need special care and equity

Since December 2019, entire world is facing problem of corona-virus pandemics and its impact on the people and their social life has been phenomenal.

Research Article

Establishment of a new reference line for 2D transperineal ultrasound in urogynecology

Abstract

Background: The purpose of this study was to establish a new, reliable and reproducible reference line for assessing bladder neck descent using 2-dimensional transperineal ultrasound. Therefore, we created a novel line, named Sym...

Case Report

COVID-19 associated hyperthyroidism due to destructive thyrotoxicosis in a young female patient

Abstract

SARS-CoV2 can induce multiple immunological and endocrinological changes. We report the case of a COVID-19 associated hyperthyroidism in a young female.

Per definition the patient – because of having given birth six weeks prev...

Review Article

COVID-19: The possible medical strategies

Abstract

In late 2019, a pandemic crisis started in Wuhan, China, swept the whole world. The disease is caused by the SARS-CoV-19 virus that belongs to the corona family of viruses. The virus mainly caused failure of respiration, and led to many deaths worldwide. The...

Research Article

Long-term results for post-interventional systemic heparinization following angioplasty of peripheral vessels

Abstract

Objective: The long-term outcome of percutaneous transluminal angioplasties is mainly determined by restenoses, either by progression of the underlying disease or by intimal hyperplasia. Pharmacological substances on the one hand...

Research Article

Influence of implantation access on complication rates in pacemaker implantation: An analysis of quality insurance data

Abstract

Purpose: According to older reports for implantation of pacemakers the access via vena cephalica (VC) is associated with less complications than the access via vena subclavia (VS), but the VS is still preferred. Valid data on hea...

Research Article

Glycosaminoglycans as Novel Targets for in vivo Contrast-Enhanced Magnetic Resonance Imaging of Atherosclerosis

Abstract

Atherosclerosis is an important promoter of cardiovascular disease potentiating myocardial infarction or stroke. Current demand in biomedical imaging necessitates noninvasive characterization of arterial changes responsible for transition of stable plaque in...

Research Article

Gender and side effects of group cognitive behavior psychotherapy

Abstract

Males and females are different in their interactional behavior, their way of suffering, and their way of expressing themselves. It is therefore supposed that they react differently in group settings. This includes the degree to which they experience burdens...

Case Report

Aortic dissection causing 2 myocardial infarctions

Abstract

A 56-year-old man was admitted to our hospital because of sudden onset of right-sided thoracic pain. The ECG showed inferior ST segment elevations. He has been treated with aspirin, clopidogrel, unfractionated heparin and tenecteplase, and his symptoms resol...

Case Report

Intracerebral Hemorrhage of Brainstem in triple pregnancy after in vitro fertilization by receiving Ovum Donation: A case report and review

Abstract

Deliveries prior to 28 weeks’ gestation (extreme preterm birth) pose a global health concern, according to the World Health Organization (WHO). Extreme preterm birth is associated with several complications in the newborn and management in neonatal...

Research Article

Biodegradation of gold and platinum implants in rats studied by electron microscopy

Abstract

Biodegradation of implanted gold in human tissue. TEM images reveal markedly biodegradation of implanted gold and re-crystallization of dissolved gold as nanoparticle of different size, shape and crystallinity. Highly crystalline icosahedral Au nanoparticle ...

Research Article

Readjustment of antithrombotic therapy in stroke-patients owing to transesophageal echocardiography findings

Objectives: Cardioembolic etiology is a frequent source of ischemic stroke. Echocardiogram is the mainstay of cardioembolic source detection with regard to plan secondary stroke management, however it remains unclear how often clinically actionable findings are ...

Research Article

Blockade of the distal sciatic nerve with the patient in the supine position using a newly developed position aid with integrated ultrasound probe holder

Abstract

Background: We have developed a femoral supporting pad with an integrated ultrasound probe holder and examined its practical usability on patients with lower limb surgery.

Objectives:

Review Article

Cardiomyopathies - The special entity of myocarditis and infl ammatory cardiomyopathy

Introduction

Cardiomyopathy is a heart muscle disease with structural and functional myocardial abnormalities in the absence of coronary artery disease, hypertension, valvular disease, and congenital heart disease. However, it has become clear that diverse etiologies...

Case Report

Autoimmune encephalitis associated with an ovarian teratoma in a 29-year old woman

Abstract

NMDA receptor encephalitis is a rare disease first described in 2007. Anti-NMDA receptor encephalitis affects mostly young women as neoplasms, mostly ovarian teratomas, are the underlying cause. The disease is caused by antibodies binding to extracellular ep...

Opinion

Psychosocial care is necessary in supporting refugees

Opinion

Between 2013 and 2016 the main tasks for the German public health care
departments were mainly related to medical support in terms of the management of outbreaks of infectious diseases, physical examinations of children and adults to exclude tube...

Research Article

“Iliosacral bridging” - A new alternative minimal invasive fixation of unstable pelvic ring fractures

Abstract

Introduction: Fractures of both the anterior and posterior pelvic ring are common injuries in polytrauma and the elderly that extend beyond those of simple low-impact trauma. While conventional X-rays predominantly show the ventr...

Case Report

Challenges in the diagnosis and management of severe Pneumocystis jirovecii pneumonia in a non-HIVinfected patient - A case report

Abstract

A 64-year-old woman was referred to our hospital due to progressive dypnoea for the past week, combined with fever and type 1 respiratory failure. White blood cell count and procalcitonin level were normal. The Chest X-ray showed bilateral disseminated pulmo...

Research Article

Electrocardiographic criteria in founder mutations related to Arrhythmogenic cardiomyopathy

Background

Founder mutations are rare causes in arrhythmogenic cardiomyopathy including TMEM43 und phospholamban mutations. The incidence is approximately 1%. P.S358L TMEM43 mutations cause aggressive, in most cases biventricular arrhythmogenic cardiomyopathy [1], wi...

Mini Review

A decade of targeted therapy for non-small cell lung cancer

Abstract

Chemotherapy is one of the main treatment options for cancer. However, chemotherapeutic agents usually suffer from poor pharmaceutical properties that restrict their use. Targeted therapy drugs have been developed to specifically target changes in c...

Case Report

Nicotinamide as a treatment option of Age-Related Macular Degeneration

Case Report

Age related macular degeneration is a severe disease of mainly elderly people and leads to central vision loss because of the degeneration of the retinal pigment epithelium [1]. Genetic and environmental factors are responsible for the accumulation of ext...

Review Article

Anxiety and depression as an effect of birth order or being an only child: Results of an internet survey in Poland and Germany

Abstract

Background: Various studies examined the effect of birth order. First born children show usually better cognitive performance than their later born siblings. Studies on emotional aspects yield heterogeneous results, sometimes in ...

Research Article

Magnetic Resonance Imaging Can Detect Symptomatic Patients with Facet Joint Pain. A Retrospective Analysis

ABSTRACT

Background: Low back pain has recently been reported as the leading cause for disability worldwide. The diagnostic value of imaging has been estimated low. Led by own positive experience, however, we hypothesized that MRI can det...

Letter to the Editor

Evaluation of ImageJ for Relative Bone Density Measurement and Clinical Application

ABSTRACT

The main method for evaluation of healing processes of the jaws in oral and maxillofacial surgery are radiological diagnostics. Quantitative description is possible by measuring the relative bone density, which puts the mean grey value of a certain area in r...

Research Article

New Approach for Analysing the Discrepancy of Pretherapeutic Tc-99m and Intra-therapeutic I-131 uptake in Scintigraphies of Thyroid Autonomies using a Parametric 3D Analysis Program

ABSTRACT

Introduction: Radioiodine therapy is a standard procedure in thyroid autonomy treatment. Discrepancies in the visual comparisons of the scintigraphies prepared for this purpose using Tc-99m-O4- and I-131 have been known for years...