Research Article

Impact of mandibular advancement device in quantitative electroencephalogram and sleep quality in mild to severe obstructive sleep apnea

<p>Sleep related breathing disorders (SRBD) are among seven well-established major categories of sleep disorders defined in the third edition of The International Classification of Sleep Disorders (ICSD-3), and Obstructive Sleep Apnea (OSA) is the most common SRBD [1,2].</p>

Research Article

Silent cerebrovascular disease in hypertensive adults is frequent and age-dependent

<h2>Abstract</h2> <p><strong>Background:</strong> Cerebral small vessel disease and extracranial atherosclerotic carotid disease are manifestations of silent cerebrovascular disease (CVD). Information on these two pathologies in hypertensive population with low cardi...

Research Article

Educational strategy to increase knowledge and risk perception about sexually transmitted infection in polytechnic students

<h2><strong>Summary</strong></h2> <p><strong>Introduction:</strong> The incidence of STI-HIV/AIDS is on the rise, making adolescents a vulnerable group at risk.</p> <p><strong>Objective:</strong> To increase the knowledge and pe...

Research Article

Clinical relevance linked to echocardiography diagnosis in Bland, White and Garland syndrome

<h2>Abstract</h2> <p><strong>Introduction:</strong> Bland, White and Garland syndrome is a coronary anomaly with high mortality without treatment. Its clinical presentation is varied which makes epidemiological documentation difficult. Echocardiography is a useful no...

Clinical Image

A rare case of abdominal pain and hematuria from retroaortic left renal vein

<h2>Clinical Image</h2> <p>A 62-year-old female with a history of arterial hypertension, attended the emergency department due to pain in the left flank. On physical examination no showed signs of peritoneal irritation. Urinalysis was indicated, that reported microscopic hematur...

Mini Review

Could metabolic risk factors contribute to the development of cervical cancer?

<h2>Abstract</h2> <p>The role of human papillomavirus infection as etiological factor for cervical squamous intraepithelial lesions and cervical cancer is well established. However, the presence of this virus is not sufficient condition for developing of cervical cancer. Current...

Research Article

Theoretical study on binding interactions of laccase-enzyme from Ganoderma weberianum with multiples ligand substrates with environmental impact

<h2>Abstract</h2> <p>Laccase catalyzes oxidation of lignin and aromatic compound with similar structure to this one. Their low substrate specificity results on degradation of similar phenolic compounds. In this context, Molecular Docking was performed with different ligands sugg...

Research Article

Design and validation of an Index to predict the development of Hypertensive Cardiopathy

<h2>Abstract</h2> <p><strong>Introduction:</strong> The high morbidity and mortality by hypertensive cardiopathy demand the construction and validation of tools to stratify the risk of developing this condition.</p> <p><strong>Objective:</stro...

Research Article

Non-hemodynamic factors associated to the risk of developing hypertensive cardiopathy

<h2>Abstract</h2> <p><strong>Introduction</strong>: Hypertensive cardiopathy is the target organ lesion caused by arterial hypertension (HTN) that exhibits the highest morbidity and mortality rates. Although the importance of hemodynamic overload exerted by HTN on th...

Letter to the Editor

The Daring of Biosimilars

<h2>Letter to Editor</h2> <p>The so-called &ldquo;biotechnological revolution&rdquo; is changing the structure of the Pharmacopoeia [1]. The space of biological products, previously limited to blood products and vaccines, grew from the introduction of first recombinant t...