Research Article

Maximal stability limits in adolescents with Tourette syndrome

Abstract

We explored if adolescents with Gilles de la Tourette syndrome (GTS) had functional postural control impairments and how these deficits are linked to a disturbance in the processing and integration of sensory information. We evaluated the displacements of th...

Research Article

Antibiotic induced changes to mitochondria result in potential contributions to carcinogenesis, heart pathologies, other medical conditions and ecosystem risks

Abstract

With the discovery by Calghatgi (2013) that three common antibiotics (Abs) increased mitochondrial reactive oxygen (ROS) and lipid peroxide (LP) and depleted their natural absorbant glutathione led me to investigate further the potential impacts of these gen...

Review Article

A proposed mechanism to explain increases in intracranial pressure: The concept of cerebral artery wedge pressure

Abstract

We hypothesize that, with elevated cerebral spinal fluid (CSF) pressure, cerebral micro-vascular obstruction and congestion may occur despite (subdural) large-vein pressures being normal. Smaller veins emptying into these larger, dura-enveloped veins are not...

Research Article

Histological clonal change - A feature for dysplasia diagnosis

Abstract

Aims: Histological diagnostic criteria are used for the assessment of the degree of dysplasia and hence the risk of cancer progression for premalignant lesions. Clonal changes in the form of hyperorthokeratosis and hyperchromasia...

Research Article

Rehabilitation of proximal humerus fractures: An environmental scan of Canadian physiotherapy practice patterns

Abstract

Background: Proximal humerus fractures (PHFs) are common injuries particularly in older adults. Evidencebased protocols for PHF rehabilitation are lacking and physiotherapists use a variety of interventions.

Review Article

The advances and challenges of Gene Therapy for Duchenne Muscular Dystrophy

ABSTRACT

Since the discovery of the dystrophin gene (DMD gene) thirty years ago, several therapeutic approaches have been investigated to treat Duchenne muscular dystrophy (DMD). This includes cell therapy, exon jumping, exonic knockout, and the CinDel method. In thi...

Research Article

Translating an Evidence-Based Physical Activity Service From Context To Context: A Single Organizational Case Study

Abstract

Background: SCI Action Canada partnered with researchers to adapt an evidence-based leisure-time physical activity (LPTA) counselling service (Get-in-Motion (GIM). A satellite GIM service called Passez à l’ac...