Editorial

Uterine Fibroid Embolization in time of Covid-19

<p>The coronavirus pandemic has caused major changes in society around the world, especially in healthcare systems. Patients with various medical ailments and conditions who were scheduled to undergo elective treatments before the pandemic arrived, wonder now if they still should follow throug...

Research Article

DSM algorithm to determine the decentralized bases of the SAMU natal through the use of simulation

<h2>Abstract</h2> <p>The growth of the urban population exerts considerable pressure on municipalities&rsquo; public managers to focus their attention on providing emergency medical care that meets the growing demand for emergency pre-hospital medical care. It is estimated t...

Research Article

3D software reconstruction for planning robotic assisted radical nephrectomy with level III caval thrombus

<p>Inferior vena cava (IVC) involvement by intraluminal extension of tumor is infrequent, occuring in 4% to 10% of patients with renal cell carcinoma (RCC) [1-5]. Based on the cephalic extension of the thrombus, Mayo [6] described a classification of inferior vena cava thrombi in 4 categories,...

Research Article

Electrocoagulation with greased lidocaine gel 2% as hemostatic maneuver after minimally invasive partial nephrectomy: Experimental and preliminary clinical results

<h2>Abstract</h2> <p><strong>Methods:</strong> Experimental phase: Performed a partial nephrectomy off clamp in pig model followed by cauterization of lidocaine gel 2% with different power (control, 30W, 50W and 100W) in the kidney resection bed to evaluate efficacy ...

Research Article

Minimally invasive gracilis muscle transposition: Initial report

<p>Rectourethral fistula (RUF) is a divesting complication after prostate cancer treatment. The RUF incidence after radical prostatectomy is about 0.5% to 2%, [1,2]. Radiotherapy, criotherapy and high intensity focused ultrasound are other more severe causes [3,4].</p>

Short Communication

Vitamin D produce antibodies in pandemic response to gripal viruses? A critical analysis

<h2>Abstract</h2> <p>In the evolutionary journey of humanity, it is possible to verify an analysis of pandemics with high occurrences. This study aims to conduct a critical analysis of the role of Vitamin D as an endogenous vaccine in the main viruses present in humanity over th...

Research Article

Evaluation of Uranium in Organs of Residents from an Uranium-Rich Region using Teeth as Bioindicators

<h2>Abstract</h2> <p>The Uranium extraction and processing plant of INB (Brazilian Nuclear Industries) is in Caetit&eacute;, a city located in a region hosting the largest Uranium reserve of the country. The degree of Uranium contamination in the Caetit&eacute; populatio...

Research Article

Anal cytology in immunocompetent patients with high-grade intraepithelial neoplasia (CIN II and CIN III)

<h2>Abstract</h2> <p><strong>Introduction:</strong> Anal cancer is directly related to the presence of high-grade HPV. Immunocompromised patients have defined conducts, something which is not observed in immunocompetent patients.</p> <p><strong>O...

Research Article

Medicinal plant extract associated with bacterial cellulose membrane: Antibacterial activity and physicochemical properties

<h2>Abstract</h2> <p>Burns injuries induce a state of immunodepression that predisposes to a bacterial infectious complication that leads to several comorbid diseases and high mortality rate. Previous studies about anti-inflammatory, antimicrobial and antioxidant properties of A...

Clinical Image

Cytomegalovirus infection in native kidney biopsy

<h2>Text</h2> <p>A 61-year-old Brazilian black woman consulted with a nephrologist due to proteinuria identified on a routine urine test. She has a personal history of thymoma resection five years ago, followed by multiple episodes of pulmonary infections including mycobacterios...

Research Article

Dry eye syndrome: Therapeutic challenges and future trends

<h2>Abstract</h2> <p><strong>Introduction:</strong> Intense Pulsed Light (IPL) is the therapeutic tool implemented in the treatment of dry eye, characterized by the emission of waves of 500-1200nm in the region of the upper and lower eyelids. Dry eye is a recurring c...

Research Article

The Renin-Angiotensin System: Alamandine is reduced in patients with Idiopathic Pulmonary Fibrosis

<h2>Abstract</h2> <p>Idiopathic Pulmonary Fibrosis (IPF) is a chronic and progressive disease without treatment that leads to death. Therefore, to control its progression to pulmonary hypertension is still a challenge. Moreover, there is no study that has investigated the Renin-...

Research Article

Correlation between the presence of maternal gestational or pre-gestational pathologies and hearing impairment in the puerperal period

<h2>Abstract</h2> <p><strong>Objective:</strong> To evaluate whether the occurrence of maternal pathologies, mainly Diabetes Mellitus and Hypertensive Syndromes in the gestational or pre-gestational period may be related to hearing impairment in postpartum women.<...

Research Article

Only low intensity of aerobic exercise improves respiratory compliance in pulmonary hypertensive rats

<h2>Abstract</h2> <p><strong>Objective:</strong> To investigate in an animal model of Pulmonary Hypertension (PH) by monocrotaline whether a lower exercise intensity, which has lower potential to provoke dyspnea symptoms, could prevent the increase the right ventricl...

Research Article

Correlation of plasma protein from MDS, young and elderly patients by SDS-page

<h2>Abstract</h2> <p><strong>Summary: </strong>Myelodysplastic Syndrome (MDS) is a heterogeneous group of clonal hematopoietic malignancies characterized by progressive cytopenias, ineffective hematopoiesis, bone marrow hypercellularity and transformation to acute my...

Research Article

Renal function effects of FDS, a saponin isolated from Filicium decipiens seeds: Biochemical and Histopathological studies

<h2>Abstract</h2> <p>Physicochemical and pharmacological studies indicated that Filicium decipiens seeds contained various specialized metabolites, including saponins. The aim of this work is to reveal the nephrotoxicity of FDS, a saponin isolated from Filicium decipiens seeds o...

Research Article

Tamsulosin and Dementia in old age: Is there any relationship?

<h2>Abstract</h2> <p>Tamsulosin is used to treat Benign Prostatic Hyperplasia (BPH), prescribed annually to about 12.6 million patients worldwide. It is an alpha-adrenergic antagonist that reduces the tone of the prostate smooth muscle involved in the pathophysiology of BPH. By ...

Research Article

Prevalence of disabling hearing loss in the elderly

<h2>Abstract</h2> <p><strong>Introduction:</strong> Disabling hearing loss refers to hearing thresholds superior than 40 dB in the better ear in the adults. The main cause of hearing loss in the elderly is the age-related hearing loss, also called presbycusis. This t...

Research Article

Evaluating cortical bone porosity using Hr-Pqct

<h2>Abstract</h2> <p>This work aims to evaluate cortical porosity through a high-resolution peripheral quantitative micro-tomography in a group of 47 patients. All patients, in vivo, were subjected to the medical care protocol of the University Hospital Clementino Fraga, 020-213...

Case Report

A case report of an Erdheim-Chester patient focused on pain management

<h2>Summary</h2> <p><strong>Introduction: </strong>Erdheim-Chester disease (ECD) is a rare and diffi cult-to-treat non-Langerhans cell histiocytosis characterized by the excessive production and accumulation of histiocytes. This study reports a case of ECD, emphasizi...

Research Article

Wound architectural analysis of 1.8mm microincision cataract surgery using spectral domain OCT

<h2>Abstract</h2> <p><strong>Purpose:</strong> Analyze Microincision Cataract surgery wound using Fourier-Domain optical coherence tomography.</p> <p><strong>Setting: </strong>Medical School of Medicine, Catholic University of Brasilia, Bra...

Research Article

Epidemiological Prevalence of Tuberculosis in the State of Maranhão between 2014 and 2016

<h2>Abstract</h2> <p><strong>Introduction:</strong> Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis (Bacillus of Koch), and presents chronic evolution affecting the lungs frequently.</p> <p><strong>Objectives:</stron...

Research Article

Is there improvement in renal function in patients undergoing bariatric surgery?

<h2>Abstract</h2> <p><strong>Introduction</strong>: Obesity may cause progressive chronic kidney disease. Weight loss in the postoperative follow-up of bariatric surgery may improve renal function in these patients. Thus, the purpose of this study was to give insight...

Research Article

Effectiveness of dexamethasone and hyaluronidase + valerate of bethasone associated with prepucial massage in the treatment of child phimosis

<h2>Abstract</h2> <p><strong>Introduction</strong>: The phimosis condition is characterized by the inability to retract the foreskin on the glans, making it impossible to expose them. Surgical treatment, although effective, has been questioned by the risk to which th...

Case Report

Benzine as fire source in operation room

<h2>Abstract</h2> <p>Provide a safety anesthesia to patient is only possible with the knowledge of material surrounding the operation room. Benzine is highly flammable substance and can produce several injures without the necessary care. This case describes a small fire caused b...

Procedure

Thirteen steps for office hysteroscopy with minimal discomfort

<h2>Abstract</h2> <p>The Office hysteroscopy (OH) is a important procedure to make diagnosis and sometimes, treatment, of intrauterine pathology, without getting the patient to Operating Room. Its advantages are very well known: less costs, fast diagnosis, see and treat and seve...

Case Report

Brachial pseudoaneurysm associated with median nerve injury as a complication of peripherally inserted central catheter: A case report

Introduction: Peripherally inserted central venous catheters (PICCs) have been increasingly used as an alternative to conventional central venous catheters for long-term administration of chemotherapy, antibiotics, parenteral nutrition, and hydration in patients with difficult...

Research Article

Evaluation of cold response in Ilex paraguariensis

<h2>Abstract</h2> <p><em>Ilex paraguariensis</em>, also known as &lsquo;Yerba mate&rsquo;, occurs naturally in Argentina, Brazil and Paraguay and is also grown in these countries with different intensities. Leaves and branches of this plant are used in the pr...

Opinion

Zoonotic potential of Giardia lamblia and control of giardiasis

<h2>Opinion</h2> <p>Giardia is the most common pathogenic intestinal flagellate protozoan in the world. The most studied species is Giardia lamblia (syn. Giardia intestinalis, Giardia duodenalis) that infects mammals, including humans.About the other seven species the scientific...

Review Article

Review of Stereotactic and Neuronavigation Brain Biopsy Methods in the Dog

<h2>Abstract</h2> <p><strong>Objective:</strong> To perform a review of brain biopsies in the canine species and determine if it is possible to compare the stereotactic and neuronavigation results.</p> <p><strong>Method:</strong> A search w...

Research Article

Trypanosoma dionisii as an experimental model to study anti-Trypanosoma cruzi drugs: A comparative analysis with benznidazole, posaconazole and amiodarone

<h2>Abstract</h2> <p>Chagas disease is a public health problem in Latin America and its treatment is based on the use of benznidazole or nifurtimox compounds. Both present problems such as resistance, inefficiency in chronic infection and cytotoxic effects. New compounds such as...

Research Article

Pharmacological effects of Nephrolepis exaltata L. (fern) aqueous extract on an insect-based model (Nauphoeta cinerea)

<h2>Abstract</h2> <p>In this work we used semi-isolated heart of the cockroach Nauphoeta cinerea for the investigation of the pharmacological effects of extracts (aqueous, 1:1, 1:2, 1:4 and 1:8) from Nephrolepis exaltata L. leaves, a popular ornamental fern considered to be safe...

Research Article

Reaction of Psidium guineense and Psidium guajava genotypes to infection of Meloidogyne enterolobii

<h2>Abstract</h2> <p>Psidium guajava (guava) is an important crop and economic resource in many tropical countries and Brazil stands out as one of its major commercial producers. The guava crop has been severely attacked by the plant parasitic nematode Meloidogyne enterolobii wh...

Research Article

Treating Blood Hypertension in a Brazilian Community: Moving from Reactive Homeostatic Model to Proactive Allostatic Healthcare

<h2>Abstract</h2> <p>The responsiveness of hypertensive subjects to different types of physical exercises and length of intervention, has been investigated in samples of our dynamic cohort study (&ldquo;Move for Health&rdquo; program) based on spontaneous demand for heal...

Case Report

Ultrasound conjugated with Laser Therapy in treatment of osteoarthritis: A case study

<h2>Abstract</h2> <p>Osteoarthritis of the hand is a chronic condition that involves hand joints, but receives less attention. Few studies have investigated the use of ultrasound therapy and laser therapy for the treatment of hand osteoarthritis.The objective was to evaluate the...

Case Report

Implications of entomological evidence during the investigation of five cases of violent death in Southern Brazil

<h2>Abstract</h2> <p>In homicide cases, knowledge about time of death is important as it directs police investigation towards the discovery of authorship, including or excluding suspects of a crime, and determining nature of death. In Brazil, entomological evidence is still negl...

Case Report

Catamenial pneumothorax: Presentation of an uncommon Pathology

The catamenial pneumothorax is defined as the accumulation of air in the pleural cavity that appears in women infrequently and spontaneously with various clinical presentations. Actually, it is considered as an extremely rare entity with few cases described in the literature, that is the reaso...

Research Article

The outcome of Acute Kidney Injury in patients with severe Malaria

<h2>Abstract</h2> <p><strong>Background</strong>: Acute kidney injury (AKI) is a frequent and serious clinical complication in patients with severe malaria. The purpose of this study was to assess the incidence of AKI in a large population of hospitalized patients wi...

Mini Review

The use of Allergoids and Adjuvants in Allergen Immunotherapy

<h2>Abstract</h2> <p><small>Allergen immunotherapy (AIT) is the unique curative treatment to help allergic patients to get over their allergies. With a personalized approach, AIT is the best example of precision medicine. After a century of intensive studies and innovative...

Research Article

Study of body composition, physiological variables in Grade III obese submitted to arm ergometer test

<h2>Abstract</h2> <p><strong>Introduction</strong>: Number of obese people is growing on a daily basis in Brazil, including morbid obese ones, but there is still a lack of studies with this subject. Due to this, the main goal of this study was to identify body profil...

Research Article

Effects of Vochysia haenkeana extract on the neuromuscular blockade induced by Bothrops jararaca venom on chick biventer cervicis preparation in vitro

<h2>SUMMARY</h2> <p>Vochysia haenkeana extract (Vh-E) was assessed against the neuromuscular blockade induced by Bothrops jararaca venom on chick biventer cervicis (BC) preparation. Pre- and post-venom incubation treatments (Pre-vit and Post-vit) were analysed here.&nbsp;Con...

Research Article

Behavioral factors of Abdominal Obesity and effects of lifestyle changes with Fiber Adequacy

<h2>ABSTRACT</h2> <p>The etiology of abdominal obesity is multifactorial and has environmental factors as its most expressive risk factors. This study cross-sectional analyzed the association of abdominal fatness with physical inactivity and food inadequacy of 1,557 subjects, bo...

Short Communication

The interaction between photonic technology and physical exercise: The action of low-level laser therapy

<h2>ABSTRACT</h2> <p><strong>Introduction</strong>: Obesity is a global-level epidemic. Together with this disease, called chronic subclinical inflammatory disease, many other diseases, known as comorbidities, arise.</p> <p><strong>Objective</...

Case Report

Acute Tubulointerstitial Nephritis due to Phenytoin: Case Report

<h2>SUMMARY</h2> <p><strong>Introduction</strong>: Acute tubulointerstitial nephritis (ATIN) is an acute kidney injury (AKI) resulting from damage to the tubulointerstitial tissue due to infection, trauma, or use of medication. It is clinically non-specific.</p>...

Short Communication

Cardiac Autonomic Modulation in children and Preadolescents obese

<h2>ABSTRACT</h2> <p>Alterations in cardiac autonomic modulation of children and obese preadolescents have attracted the attention of researchers around the world. These alterations cause disorders in the cardiac autonomic control and can interfere in cardiac output and in the h...

Research Article

The lifestyle modification effectiveness in reducing Hypertension in a Brazilian Community: From the epigenetic basis of Ancestral Survival to the Contemporary Lifestyle and Public Health Initiatives

<h2>Abstract</h2> <p>High blood pressure (HBP) is a strong, independent and etiologically relevant risk factor for cardiovascular and therefore, the leading cause of preventable deaths worldwide. Hypertension has high medical and social costs. Due to its many associated complica...

Research Article

Effects of a short Cardiovascular Rehabilitation program in Hypertensive subjects: A Pilot Study

<h2>Abstract</h2> <p>Systemic arterial hypertension (SAH) is considered an important risk factor for the development of cardiovascular diseases. The aim of the present study was to verify the effects of a short cardiovascular rehabilitation program (CR) in hypertensive subjects....

Case Report

External Root Resorption associated with Impacted Third Molars: A Case Report

<h2>ABSTRACT</h2> <p>The indications for impacted third molar extraction include the prevention of dental reabsorption on the adjacent tooth. Resorption can be classified as physiological (when deciduous teeth are exfoliated) or pathological (when caused by injury or irritation ...

Short Communication

Insights for Antihypertensive pharmacotherapy from the“Calcium Paradox” due to Ca2+/camp Interaction

<h2>Abstract</h2> <p>Several experimental studies performed since 1975, using smooth muscles richly innervated by sympathetic nerves to exclude the autonomic influence of adjusting reflex (rodent vas deferens), showed that L-type voltage-activated Ca2+ channels (VACC) blockers c...

Case Report

Diagnosis and Treatment of Anterior Cracked Tooth: A Case Report

<h2>Abstract</h2> <p><strong>Background: </strong>A cracked tooth may be challenging for dentists because it may present with varied intensities, may be asymptomatic, and may still not be clinically visible. The transilumination method can facilitate diagnosis and en...