Research Article

Radiofrequency vs. scalpel incision for upper blepharoplasty: A clinicopathologic and photo comparison

<h2>Abstract</h2> <p><strong>Objective:</strong> The aim of this study is to compare scar appearance and the histopathological aspects of inflammatory response induced by the use of radiofrequency [RF] incision and a cold-blade scalpel incision in upper blepharoplast...

Clinical Image

Cytomegalovirus infection in native kidney biopsy

<h2>Text</h2> <p>A 61-year-old Brazilian black woman consulted with a nephrologist due to proteinuria identified on a routine urine test. She has a personal history of thymoma resection five years ago, followed by multiple episodes of pulmonary infections including mycobacterios...

Research Article

Dry eye syndrome: Therapeutic challenges and future trends

<h2>Abstract</h2> <p><strong>Introduction:</strong> Intense Pulsed Light (IPL) is the therapeutic tool implemented in the treatment of dry eye, characterized by the emission of waves of 500-1200nm in the region of the upper and lower eyelids. Dry eye is a recurring c...

Research Article

The Renin-Angiotensin System: Alamandine is reduced in patients with Idiopathic Pulmonary Fibrosis

<p>Idiopathic Pulmonary Fibrosis (IPF) is a chronic and progressive disease without treatment that leads to death. Therefore, to control its progression to pulmonary hypertension is still a challenge. Moreover, there is no study that has investigated the Renin-Angiotensin System in patients wi...

Research Article

Correlation between the presence of maternal gestational or pre-gestational pathologies and hearing impairment in the puerperal period

<h2>Abstract</h2> <p><strong>Objective:</strong> To evaluate whether the occurrence of maternal pathologies, mainly Diabetes Mellitus and Hypertensive Syndromes in the gestational or pre-gestational period may be related to hearing impairment in postpartum women.<...

Research Article

Only low intensity of aerobic exercise improves respiratory compliance in pulmonary hypertensive rats

Objective: To investigate in an animal model of Pulmonary Hypertension (PH) by monocrotaline whether a lower exercise intensity, which has lower potential to provoke dyspnea symptoms, could prevent the increase the right ventricle pressure and the decrease in respiratory compl...

Research Article

Correlation of plasma protein from MDS, young and elderly patients by SDS-page

Summary: Myelodysplastic Syndrome (MDS) is a heterogeneous group of clonal hematopoietic malignancies characterized by progressive cytopenias, ineffective hematopoiesis, bone marrow hypercellularity and transformation to acute myeloid leukemia (AML).
Objectives: Identi...

Research Article

Renal function effects of FDS, a saponin isolated from Filicium decipiens seeds: Biochemical and Histopathological studies

Physicochemical and pharmacological studies indicated that Filicium decipiens seeds contained various specialized metabolites, including saponins. The aim of this work is to reveal the nephrotoxicity of FDS, a saponin isolated from Filicium decipiens seeds on male Wistar rats histopathological...

Research Article

Tamsulosin and Dementia in old age: Is there any relationship?

Tamsulosin is used to treat Benign Prostatic Hyperplasia (BPH), prescribed annually to about 12.6 million patients worldwide. It is an alpha-adrenergic antagonist that reduces the tone of the prostate smooth muscle involved in the pathophysiology of BPH. By acting on alpha 1A receptors, predom...

Research Article

Prevalence of disabling hearing loss in the elderly

<h2>Abstract</h2> <p><strong>Introduction:</strong> Disabling hearing loss refers to hearing thresholds superior than 40 dB in the better ear in the adults. The main cause of hearing loss in the elderly is the age-related hearing loss, also called presbycusis. This t...

Research Article

Evaluating cortical bone porosity using Hr-Pqct

This work aims to evaluate cortical porosity through a high-resolution peripheral quantitative micro-tomography in a group of 47 patients. All patients, in vivo, were subjected to the medical care protocol of the University Hospital Clementino Fraga, 020-213. Patients were women aged from 37 t...

Case Report

A case report of an Erdheim-Chester patient focused on pain management

Introduction: Erdheim-Chester disease (ECD) is a rare and diffi cult-to-treat non-Langerhans cell histiocytosis characterized by the excessive production and accumulation of histiocytes. This study reports a case of ECD, emphasizing both its diagnosis, assessment and treatment...

Research Article

Wound architectural analysis of 1.8mm microincision cataract surgery using spectral domain OCT

Purpose: Analyze Microincision Cataract surgery wound using Fourier-Domain optical coherence tomography.

Setting: Medical School of Medicine, Catholic University of Brasilia, Brasília, Brazil.

Design: Prospective c...

Research Article

Epidemiological Prevalence of Tuberculosis in the State of Maranhão between 2014 and 2016

Introduction: Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis (Bacillus of Koch), and presents chronic evolution affecting the lungs frequently.

Objectives: Analyse, in the state of Maranhão, the epidemiological pre...

Research Article

Is there improvement in renal function in patients undergoing bariatric surgery?

Introduction: Obesity may cause progressive chronic kidney disease. Weight loss in the postoperative follow-up of bariatric surgery may improve renal function in these patients. Thus, the purpose of this study was to give insight on the subject using a sensible biomarker.

Research Article

Effectiveness of dexamethasone and hyaluronidase + valerate of bethasone associated with prepucial massage in the treatment of child phimosis

Introduction: The phimosis condition is characterized by the inability to retract the foreskin on the glans, making it impossible to expose them. Surgical treatment, although effective, has been questioned by the risk to which the patient is exposed. Therefore, we have opted f...

Case Report

Benzine as fire source in operation room

Provide a safety anesthesia to patient is only possible with the knowledge of material surrounding the operation room. Benzine is highly flammable substance and can produce several injures without the necessary care. This case describes a small fire caused by the presence of benzine in the sur...

Procedure

Thirteen steps for office hysteroscopy with minimal discomfort

<h2>Abstract</h2> <p>The Office hysteroscopy (OH) is a important procedure to make diagnosis and sometimes, treatment, of intrauterine pathology, without getting the patient to Operating Room. Its advantages are very well known: less costs, fast diagnosis, see and treat and seve...

Case Report

Brachial pseudoaneurysm associated with median nerve injury as a complication of peripherally inserted central catheter: A case report

Introduction: Peripherally inserted central venous catheters (PICCs) have been increasingly used as an alternative to conventional central venous catheters for long-term administration of chemotherapy, antibiotics, parenteral nutrition, and hydration in patients with difficult...

Research Article

Evaluation of cold response in Ilex paraguariensis

Ilex paraguariensis, also known as ‘Yerba mate’, occurs naturally in Argentina, Brazil and Paraguay and is also grown in these countries with different intensities. Leaves and branches of this plant are used in the preparation of a stimulant beverage that beside social imp...

Opinion

Zoonotic potential of Giardia lamblia and control of giardiasis

Giardia is the most common pathogenic intestinal flagellate protozoan in the world. The most studied species is Giardia lamblia (syn. Giardia intestinalis, Giardia duodenalis) that infects mammals, including humans.About the other seven species the scientific literature is very scarce and litt...

Review Article

Review of Stereotactic and Neuronavigation Brain Biopsy Methods in the Dog

Objective: To perform a review of brain biopsies in the canine species and determine if it is possible to compare the stereotactic and neuronavigation results.

Method: A search was performed in NCBI’s PubMed database for stereotactic or neuron...

Research Article

Trypanosoma dionisii as an experimental model to study anti-Trypanosoma cruzi drugs: A comparative analysis with benznidazole, posaconazole and amiodarone

Chagas disease is a public health problem in Latin America and its treatment is based on the use of benznidazole or nifurtimox compounds. Both present problems such as resistance, inefficiency in chronic infection and cytotoxic effects. New compounds such as posaconazole and amiodarone have be...

Research Article

Pharmacological effects of Nephrolepis exaltata L. (fern) aqueous extract on an insect-based model (Nauphoeta cinerea)

In this work we used semi-isolated heart of the cockroach Nauphoeta cinerea for the investigation of the pharmacological effects of extracts (aqueous, 1:1, 1:2, 1:4 and 1:8) from Nephrolepis exaltata L. leaves, a popular ornamental fern considered to be safe.The use of insects in experimental ...

Research Article

Reaction of Psidium guineense and Psidium guajava genotypes to infection of Meloidogyne enterolobii

Psidium guajava (guava) is an important crop and economic resource in many tropical countries and Brazil stands out as one of its major commercial producers. The guava crop has been severely attacked by the plant parasitic nematode Meloidogyne enterolobii which has caused drastic reduction of ...

Research Article

Treating Blood Hypertension in a Brazilian Community: Moving from Reactive Homeostatic Model to Proactive Allostatic Healthcare

The responsiveness of hypertensive subjects to different types of physical exercises and length of intervention, has been investigated in samples of our dynamic cohort study (“Move for Health” program) based on spontaneous demand for healthy lifestyle with supervised exercises and ...

Case Report

Ultrasound conjugated with Laser Therapy in treatment of osteoarthritis: A case study

<h2>Abstract</h2> <p>Osteoarthritis of the hand is a chronic condition that involves hand joints, but receives less attention. Few studies have investigated the use of ultrasound therapy and laser therapy for the treatment of hand osteoarthritis.The objective was to evaluate the...

Case Report

Implications of entomological evidence during the investigation of five cases of violent death in Southern Brazil

In homicide cases, knowledge about time of death is important as it directs police investigation towards the discovery of authorship, including or excluding suspects of a crime, and determining nature of death. In Brazil, entomological evidence is still neglected by official forensic organizat...

Case Report

Catamenial pneumothorax: Presentation of an uncommon Pathology

The catamenial pneumothorax is defined as the accumulation of air in the pleural cavity that appears in women infrequently and spontaneously with various clinical presentations. Actually, it is considered as an extremely rare entity with few cases described in the literature, that is the reaso...

Research Article

The outcome of Acute Kidney Injury in patients with severe Malaria

Background: Acute kidney injury (AKI) is a frequent and serious clinical complication in patients with severe malaria. The purpose of this study was to assess the incidence of AKI in a large population of hospitalized patients with a primary admission diagnosis of malaria, and...

Mini Review

The use of Allergoids and Adjuvants in Allergen Immunotherapy

Allergen immunotherapy (AIT) is the unique curative treatment to help allergic patients to get over their allergies. With a personalized approach, AIT is the best example of precision medicine. After a century of intensive studies and innovative discoveries, allergists have in their han...

Research Article

Study of body composition, physiological variables in Grade III obese submitted to arm ergometer test

<h2>Abstract</h2> <p><strong>Introduction</strong>: Number of obese people is growing on a daily basis in Brazil, including morbid obese ones, but there is still a lack of studies with this subject. Due to this, the main goal of this study was to identify body profil...

Research Article

Effects of Vochysia haenkeana extract on the neuromuscular blockade induced by Bothrops jararaca venom on chick biventer cervicis preparation in vitro

Vochysia haenkeana extract (Vh-E) was assessed against the neuromuscular blockade induced by Bothrops jararaca venom on chick biventer cervicis (BC) preparation. Pre- and post-venom incubation treatments (Pre-vit and Post-vit) were analysed here. Contractures ACh (110 µM) and KCl (2...

Research Article

Behavioral factors of Abdominal Obesity and effects of lifestyle changes with Fiber Adequacy

<h2>ABSTRACT</h2> <p>The etiology of abdominal obesity is multifactorial and has environmental factors as its most expressive risk factors. This study cross-sectional analyzed the association of abdominal fatness with physical inactivity and food inadequacy of 1,557 subjects, bo...

Short Communication

The interaction between photonic technology and physical exercise: The action of low-level laser therapy

<h2>ABSTRACT</h2> <p><strong>Introduction</strong>: Obesity is a global-level epidemic. Together with this disease, called chronic subclinical inflammatory disease, many other diseases, known as comorbidities, arise.</p> <p><strong>Objective</...

Case Report

Acute Tubulointerstitial Nephritis due to Phenytoin: Case Report

Introduction: Acute tubulointerstitial nephritis (ATIN) is an acute kidney injury (AKI) resulting from damage to the tubulointerstitial tissue due to infection, trauma, or use of medication. It is clinically non-specific.

Case: A teenager with...

Short Communication

Cardiac Autonomic Modulation in children and Preadolescents obese

<h2>ABSTRACT</h2> <p>Alterations in cardiac autonomic modulation of children and obese preadolescents have attracted the attention of researchers around the world. These alterations cause disorders in the cardiac autonomic control and can interfere in cardiac output and in the h...

Research Article

The lifestyle modification effectiveness in reducing Hypertension in a Brazilian Community: From the epigenetic basis of Ancestral Survival to the Contemporary Lifestyle and Public Health Initiatives

High blood pressure (HBP) is a strong, independent and etiologically relevant risk factor for cardiovascular and therefore, the leading cause of preventable deaths worldwide. Hypertension has high medical and social costs. Due to its many associated complications, the use of medical services c...

Research Article

Effects of a short Cardiovascular Rehabilitation program in Hypertensive subjects: A Pilot Study

<h2>Abstract</h2> <p>Systemic arterial hypertension (SAH) is considered an important risk factor for the development of cardiovascular diseases. The aim of the present study was to verify the effects of a short cardiovascular rehabilitation program (CR) in hypertensive subjects....

Case Report

External Root Resorption associated with Impacted Third Molars: A Case Report

The indications for impacted third molar extraction include the prevention of dental reabsorption on the adjacent tooth. Resorption can be classified as physiological (when deciduous teeth are exfoliated) or pathological (when caused by injury or irritation to the periodontal ligament). Many c...

Short Communication

Insights for Antihypertensive pharmacotherapy from the“Calcium Paradox” due to Ca2+/camp Interaction

Several experimental studies performed since 1975, using smooth muscles richly innervated by sympathetic nerves to exclude the autonomic influence of adjusting reflex (rodent vas deferens), showed that L-type voltage-activated Ca2+ channels (VACC) blockers completely inhibited neuro...

Case Report

Diagnosis and Treatment of Anterior Cracked Tooth: A Case Report

Background: A cracked tooth may be challenging for dentists because it may present with varied intensities, may be asymptomatic, and may still not be clinically visible. The transilumination method can facilitate diagnosis and ensure appropriate treatment in such cases. The ai...

Mini Review

Novel Challenges for the Therapeutics of Depression: Pharmacological Modulation of Interaction between the Intracellular Signaling Pathways Mediated by Ca2+ and cAMP

Depression is a psychiatric disease resulting mainly by dysfunction of serotoninergic and monoaminergic neurotransmission in central nervous system (CNS). Due to the multifaceted nature of depression and our limited understanding on its etiology, depression is difficult to be treated with curr...

Case Report

Recurrent Peripheral Ameloblastoma of the Mandible: A Case Report

Ameloblastoma is the second most common odontogenic tumor being back only for the odontoma. An unusual case of recurrent peripheral ameloblastoma in the mandible from the site of previous occurrence, reducing oropharyngeal space due compression by lesion. Panoramic radiography not showed prese...

Research Article

Kinematics and Electromyographic Analysis of Gait with Different Footwear

Kinematic analysis and surface electromyography are tools being used as important methods to evaluate the human gait and to analyze different types of footwear aiming modifications and adaptations to the human locomotor system, especially of the feet. The aim of the present study was to analyz...

Short Communication

The “Calcium Paradox” Due To Ca2+/Camp Interaction: New Insights for the Neuroscience Field

In the cardiovascular field, tachycardia and increment of catecholamine plasma levels (sympathetic hyperactivity) have been reported by hypertensive patients that use L-type Ca2+ channel blockers (CCBs) since 70´s. Our discovery of the involvement of interaction between the intracellular...